Psychoneuroimmunoendocrinological and neuroanatomical basis of suicidal behavior: potential therapeutic strategies with a focus on transcranial magnetic stimulation (TMS) by Hesed Virto-Farfan, Gustavo E. Tafet

“…Dysfunctions in these circuits contribute to heightened impulsivity, impaired decision-making, and emotional dysregulation in individuals with suicidal behavior. Structural and functional abnormalities in the DLPFC, coupled with altered neurotransmitter systems and inflammatory markers, have been consistently linked to suicidality. …”
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Complexities in diagnosis and treatment of medullary thyroid cancer. Clinical observation by E. V. Frolova, N. N. Naumova, E. V. Salautin, E. A. Volodina

“…To date, the number of referrals from patients with minimal structural and functional changes in the thyroid gland is small, which indicates that the disease is often diagnosed at a later date. …”
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The cys-loop ligand-gated ion channel gene superfamily of the Colorado potato beetle, Leptinotarsa decemlineata by Dongxu Chen, David J. Hawthorne

“…Alternative splicing and RNA editing conserved in insect species were also identified in expected subunits, potentially contributing to structural and functional diversity of the receptor. …”
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Conservation’s green illusion: Nitrogen thresholds as critical determinants of extinction risk in specialist herbivores by Saroj Shrestha

“…Sub-threshold habitats can function as ecological traps, silently undermining translocation, reproduction, and survival even in structurally intact forests. …”
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Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South... by Angelique Hölzemer, Christina F Thobakgale, Camilo A Jimenez Cruz, Wilfredo F Garcia-Beltran, Jonathan M Carlson, Nienke H van Teijlingen, Jaclyn K Mann, Manjeetha Jaggernath, Seung-gu Kang, Christian Körner, Amy W Chung, Jamie L Schafer, David T Evans, Galit Alter, Bruce D Walker, Philip J Goulder, Mary Carrington, Pia Hartmann, Thomas Pertel, Ruhong Zhou, Thumbi Ndung'u, Marcus Altfeld

“…Better understanding of the mechanisms by which HIV-1 evades NK-cell-mediated immune pressure and the functional validation of a structural modeling approach will facilitate the development of novel targeted immune interventions to harness the antiviral activities of NK cells.…”
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A multi-graph convolutional network method for Alzheimer’s disease diagnosis based on multi-frequency EEG data with dual-mode connectivity by Qingjie Xu, Qingjie Xu, Libing An, Haiqiang Yang, Haiqiang Yang, Keum-Shik Hong, Keum-Shik Hong

“…This method integrates both functional and structural connectivity to more thoroughly capture the relationships among brain regions. …”
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Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances by Qiu Jiang, Jie Liu, Shan Huang, Xuan-Yue Wang, Xiaowei Chen, Guang-Hui Liu, Keqiang Ye, Weihong Song, Colin L. Masters, Jun Wang, Yan-Jiang Wang

“…Thus, we aim to elucidate the role of ageing in neurodegenerative diseases from the perspective of a complex system, in which the brain is the core and peripheral organs and tissues form a holistic network to support brain functions. During ageing, the progressive deterioration of the structure and function of the entire body hampers its active and adaptive responses to various stimuli, thereby rendering individuals more vulnerable to neurodegenerative diseases. …”
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Issues of Interpretation and Application of the Notion of “International Legal Legitimation” by A. M. Korzhenyak

“…On the basis of integrative (multidimensional) approach to scientific legal research, taking into account such principles of scientific cognition as theoretical novelty and scientific relevance, the study was guided, in particular, by hermeneutic, formal-legal, formallogical, structural-functional and systematic methods, as well as methods of analysis and synthesis, legal modelling, legal construction and strategic planning.RESEARCH RESULTS. …”
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The Mediating Role of Self-Efficacy in the Relationship Between Locus of Control and Resilience in Primary School Students by Asimenia Papoulidi, Katerina Maniadaki

“…The results indicated that locus of control and self-efficacy function as significant predictors for all dimensions of resilience, while demographic characteristics such as gender and grade only predict some dimensions of resilience. …”
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Connecting the Dots: Linking Centrality Measures to Peer Perceptions in Elementary School Friendship Networks by Prochnow Tyler, Keightley Samuel, Patterson Megan S., Lease Michele

“…This study highlights the complex interplay between structural positions in social networks and peer perceptions of social functioning. …”
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The regulatory variant rs1950834 confers the risk of depressive disorder by reducing LRFN5 expression by Di Luan, Yifan Li, Aini Zhang, Qingqing Bai, Te Zhao, Xi Chen, Xinglun Dang, Junyang Wang, Shaolei Jiang, Yun Sun, Yingjie Zhu, Yan Kong, Xiong-Jian Luo, Zhijun Zhang

“…These findings reveal that the functional risk single nucleotide polymorphism rs1950834 at 14q21.1 regulates LRFN5 expression and function in NAc, providing a novel perspective for molecular diagnosis and targeted interventions of MDD.…”
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Harnessing exercise to combat chronic diseases: the role of Drp1-Mediated mitochondrial fission by Yingxin Sun, Junchen He, Junchen He, Lei Bao, Xiaoming Shi, Jinghong Wang, Qingwen Li

“…This, in turn, enhances mitochondrial function and cellular metabolism. This review synthesizes the current understanding of Drp1 structure and activation mechanisms, and analyzes the effects of exercise interventions on Drp1-mediated mitochondrial fission in different disease models to improve common chronic conditions. …”
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Left ventricular flow dynamics by cardiac imaging techniques in heart failure patients: state of the art by Donato Mele, Lorenzo Serio, Riccardo Beccari, Antonella Cecchetto, Stefano Nistri, Gianni Pedrizzetti

“…Abstract Background The evaluation of left ventricular (LV) flow dynamics is a novel approach to assessing LV function that goes beyond traditional metrics. This approach has been applied to patients with heart failure (HF), providing valuable insights that are discussed in this review, with the aim of enhancing our understanding of LV function in the context of the HF syndrome. …”
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The use of bone autoplasty for false joints of the humerus diaphysis by K. I. Khorak, P. G. Kogan, D. G. Parfeev, A. I. Avdeev, A. M. Morozov, M. E. Piskareva

“…Over the last decades, clinical practice has changed many approaches to the tactics and choice of therapeutic means to restore bone integrity, as well as to restore the supporting and motor functions of the traumatized limb. Analysis of the data obtained from the literature has shown that the best results in the treatment of false joints of the humerus diaphysis were demonstrated by the techniques combining the use of bone autoplasty and additional metal structures.…”
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Diet-Induced Proteomic and Metabolomic Signatures in Chronic Kidney Disease: A Precision Nutrition Approach by Sandra Cabała, Agnieszka Herosimczyk

“…Additionally, several studies explore specific metabolites found in biological fluids and renal tissue in response to protein-rich foods, assessing their potential roles in a progressive loss of kidney function. Emerging evidence also suggests that dietary interventions targeting the gut microbiota may help alleviate inflammation, oxidative stress, and toxin accumulation in chronic kidney disease. …”
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Association of body mass index and sexual dysfunction among married women in Makkah City, Saudi Arabia by Lujain Safwan Filfilan, Nesrin Kamal Abd El-Fatah

“…Participants completed a structured questionnaire assessing sociodemographics, medical history, reproductive health, and sexual function using the validated Arabic Female Sexual Function Index (ArFSFI). …”
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Exosome Therapy in Stress Urinary Incontinence: A Comprehensive Literature Review by Manouchehr Nasrollahzadeh Saravi, Mahdi Mohseni, Iman Menbari Oskouie, Jafar Razavi, Ernesto Delgado Cidranes, Masoumeh Majidi Zolbin

“…Exosome therapy has the potential to enhance tissue regeneration, restore urethral function, and repair nerve and muscle damage, thereby reducing symptom burden and improving patients’ quality of life. …”
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METAB‐HTX: prospective, longitudinal cohort study evaluating cardiac and systemic metabolism after heart transplantation by Amin Polzin, Daniel Scheiber, Fabian Voss, Jean Haurand, Elric Zweck, Daniel Oehler, Oliver Maier, Mareike Cramer, Maximilian Spieker, Constanze Moos, Ursala Tokhi, David Naguib, Philipp Mourikis, Marcel Benkhoff, Robert Wagner, Michael Roden, Heinz‐Peter Schultheiss, Sascha Dietrich, Hug Aubin, Udo Boeken, Artur Lichtenberg, Malte Kelm

“…Kidney and liver function and structural alterations will be evaluated. …”
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Protocol for a multisite randomised trial of Hand–Arm Bimanual Intensive Training Including Lower Extremity training for children with bilateral cerebral palsy: HABIT-ILE Australia... by Roslyn N Boyd, Leanne Sakzewski, Mark Chatfield, Yannick Bleyenheuft, Iona Novak, Catherine Elliott, Sarah Reedman, Cathy Morgan, Kerstin Pannek, Jurgen Fripp, Prue Golland, David Rowell, Robert Stuart Ware

“…Primary outcomes will be the Gross Motor Function Measure and ABILHAND-Kids. Secondary outcomes will be brain structural integrity, walking endurance, bimanual hand performance, self-care, mobility, performance and satisfaction with individualised goals, and QOL. …”
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Monitoring cognitive resilience in military personnel in extreme operational environments: The role of smart technologies and nutritional strategies-A scoping review protocol. by Rodica Siminiuc, Dinu Turcanu

“…<h4>Materials and methods</h4>This scoping review follows the JBI methodology, with a structured study selection and data synthesis process. …”
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