Research Progress on the Mechanism of Acupuncture Treatment of Ischemic Stroke Based on the Space Construction of Nerve-vascular Unit by LI Mengxing, WNAG Yu, LI Zhen, LIU Fang, SHI Kejian

“…It is mainly discussed on acupuncture research from the structural function of NVU to the spatial structure changes in IS, with neurons as the one-dimensional target, neurons, brain microvascular endothelial cells (BMEC) as the two-dimensional target, and with neurons, BMEC and glial cells as the multi-dimensional target.ResultsMost of the previous studies on acupuncture treatment of IS only stayed at a single level of neuron or angiogenesis regulation, and rarely involved the research on the overall NVU and the interaction among its components. …”
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The characteristics of anhedonia in depression: a review from a clinically oriented perspective by Congchong Wu, Qingli Mu, Weijia Gao, Shaojia Lu

“…At the biological level, MDD patients with anhedonia seem to present higher levels of inflammatory factors, abnormal metabolic function and hypermetabolism of BDNF. In brain imaging studies, there are some structural and/ or functional changes in multiple brain regions of subcortical and cortical areas, as well as the limbic system in MDD patients with anhedonia. …”
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The oily nucleus– role of phospholipids in genome biology: membrane-directed roles and signaling in the nucleoplasm by Zobia Umair, Zahid Nawaz, Sumaiya Hasnain, Wolfgang Fischle

“…Nonetheless, in recent years, the impact of nuclear phospholipids on the structure and function of the genome has been found to be more multifaceted and complex. …”
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Rethinking Osteoarthritis Management: Synergistic Effects of Chronoexercise, Circadian Rhythm, and Chondroprotective Agents by Eloy del Río

“…Conventional management approaches often rely on fragmented and poorly coordinated pharmacological and non-pharmacological interventions that are inconsistently applied throughout the disease course. …”
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Membraneless organelles in health and disease: exploring the molecular basis, physiological roles and pathological implications by Yangxin Li, Yuzhe Liu, Xi-Yong Yu, Yan Xu, Xiangbin Pan, Yi Sun, Yanli Wang, Yao-Hua Song, Zhenya Shen

“…Abstract Once considered unconventional cellular structures, membraneless organelles (MLOs), cellular substructures involved in biological processes or pathways under physiological conditions, have emerged as central players in cellular dynamics and function. …”
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Funding the future: safeguarding pediatric health equity through CMS and CHIP by Carlie N. Myers, Meera Rao, Rishiraj Bandi, Sebastian Densley, Daniella Diaz, Michelle Knecht, Lea Sacca

“…Interventions reviewed include Functional Family Therapy (FFT) for adjudicated youth, a hospital-led asthma management initiative in Ohio, community-based care engagement strategies in disorganized Chicago neighborhoods, and a national policy analysis of CHIP's effectiveness. …”
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The Application of Diaphragm Ultrasound in Chronic Obstructive Pulmonary Disease: A Narrative Review by Heng Mu, Qunxia Zhang

“…Thus, it serves to provide valuable insights for clinical monitoring of diaphragm function in COPD patients, facilitating early clinical intervention and aiding in the recovery of diaphragm function.…”
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Short-chain polyphosphates induce tau fibrillation and neurotoxicity in human iPSC-derived retinal neurons by Lorenzo Barolo, Lorenza Mautone, Ylenia Gigante, Silvia Ghirga, Francesco Mura, Maria Vittoria Farina, Stefano Tacconi, Luciana Dini, Giancarlo Ruocco, Alberto Boffi, Edoardo Milanetti, Silvia Di Angelantonio, Paola Baiocco

“…Abstract The onset of Alzheimer’s Disease and Frontotemporal Dementia is closely associated with the aggregation of tau, a multifunctional protein essential for neuronal stability and function. Given the role of tau aggregation in neurodegeneration, understanding the mechanisms behind its fibril formation is crucial for developing therapeutic interventions to halt or reverse disease progression. …”
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Portugal’s Wattle and Daub Constructive Legacy by Kátia Soares, Isabel Torres, Ana Velosa

“…The commitment to technical and scientific innovation for appropriate interventions in buildings with wattle and daub walls requires a comprehensive and authentic approach to pre-existing structures. …”
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A modern view on the mechanisms of diabetic cardiomyopathy development and the its modification options by A. G. Sorokina, Ya. A. Orlova

“…The article is an analytical review of clinical studies  of structural  and  functional cardiac changes in patients with diabetes. …”
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Neuroimaging and Emotional Development in the Pediatric Population: Understanding the Link Between the Brain, Emotions, and Behavior by Giuseppe Marano, Maria Benedetta Anesini, Miriam Milintenda, Mariateresa Acanfora, Claudia Calderoni, Francesca Bardi, Francesco Maria Lisci, Caterina Brisi, Gianandrea Traversi, Osvaldo Mazza, Roberto Pola, Gabriele Sani, Eleonora Gaetani, Marianna Mazza

“…This narrative scoping review synthesizes current pediatric neuroimaging evidence, filling a gap in the literature by integrating structural, functional, and emerging modalities, to provide clear translational pathways for clinical and behavioral observations. …”
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Ultrastructural mitral valve abnormalities in infective endocarditis by R. A. Mukhamadiyarov, A. G. Kutikhin

“…We examined 9 mitral valves extracted during surgical interventions due to structural malfunction in patients with infective endocarditis (IE). …”
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Virtual and Augmented Reality for Chronic Musculoskeletal Rehabilitation: A Systematic Review and Exploratory Meta-Analysis by Theodora Plavoukou, Pantelis Staktopoulos, Georgios Papagiannis, Dimitrios Stasinopoulos, George Georgoudis

“…<b>Objective:</b> To systematically evaluate the effectiveness of VR, AR, and exergaming interventions in improving pain, function, balance, and psychological outcomes among adults with CMDs. …”
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Mesoscale connectivity of the human hippocampus and fimbria revealed by ex vivo diffusion MRI by Madeline McCrea, Navya Reddy, Kathryn Ghobrial, Ryan Ahearn, Ryan Krafty, T. Kevin Hitchens, Jorge Martinez-Gonzalez, Michel Modo

“…Elucidating the detailed structural connectivity of the hippocampus is crucial to develop better diagnostic markers of neurological and psychiatric conditions, as well as to devise novel surgical interventions.…”
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Perceived social support on objective measured sedentary behavior of stroke patients: the mediating role of exercise self-efficacy by Jianing Wei, Fanjiayi Yang, Xiaofang Dong

“…IntroductionAs stroke patients may have impaired motor function, there may have increased sedentary behavior. …”
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Stem-Cell Niches in Health and Disease: Microenvironmental Determinants of Regeneration and Pathology by Boris Yushkov, Valerii Chereshnev, Elena Korneva, Victoria Yushkova, Alexey Sarapultsev

“…Emphasis is placed on how aging, inflammation, fibrosis, and metabolic stress disrupt niche function, converting supportive environments into autonomous drivers of pathology. …”
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Molecular Dynamics of Apolipoprotein Genotypes APOE4 and SNARE Family Proteins and Their Impact on Alzheimer’s Disease by Yuqing Wang, Xuefeng Liu, Pengtao Zheng, Qing Xie, Chenxiang Wang, Chaoyang Pang

“…This work highlights the perturbations in synaptic function mediated by APOE4, which may offer novel insights into the molecular underpinnings of AD. …”
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Social support and adolescent mental health in Kenya: a parallel mediation analysis of perceived control and gratitude by Ming Zhao, Heng Miao, Li-Li Zhu, Xiao-Han Zhang, Li-Wei Zang

“…These psychological resources function as parallel pathways linking social connections to well-being. …”
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The importance of good adherence to methotrexate in the treatment of rheumatoid arthritis by Ćeranić Jelena, Kisić-Tepavčević Darija, Ristić Gorica

“…Methotrexate affects the function of almost all cell types involved in inflammation (neutrophils, monocytes, Tand B-cells, endothelial cells, and fibroblast-like synovium). …”
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A serial mediation model of physical exercise and loneliness: the role of frailty and depression by Song Gu, Shiling Liu

“…Physical exercise has been widely recognized as an effective intervention to improve both the physical and mental health of older adults. …”
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