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Structural characterization and protective effects of polysaccharides isolated from Berberis dasystachya M. fruits on H2O2-induced oxidative damage in RINm5F pancreatic β-cells
Published 2025-08-01“…Our previous research demonstrated the hypoglycemic and antioxidant properties of crude polysaccharides from Berberis dasystachya M. (BDP), but the structural characteristics and underlying mechanisms were unclear. …”
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502
Effect of Baduanjin exercise in a blended online-offline model on cognitive function and peripheral blood BDNF levels in older adults
Published 2025-06-01“…Cognitive function and peripheral blood BDNF levels were assessed prior to and following the 12-week intervention.Results(1) After 12-week intervention, BG exhibited significant improvements in MoCA (P < 0.01), and MoCA of BG was significantly higher than CG (P < 0.05). (2) After 12-week intervention, BG exhibited significant improvements in DST-F (P < 0.05), DST-B (P < 0.05), VFT (P < 0.01), Stroop-A (P < 0.05), and Stroop-RT (P < 0.05). …”
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503
Pain, Function, and Elastosonographic Assessment After Shockwave Therapy in Non-Calcific Supraspinatus Tendinopathy: A Retrospective Observational Study
Published 2025-01-01“…<b>Conclusions:</b> ESWT significantly reduces tendon thickness and enhances elasticity, correlating with improvements in pain and functional scores. SWE proved to be a reliable method for monitoring structural and clinical changes in SNCCT. …”
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504
Structure-guided screening identified bioactive phytoconstituents Hernandonine and Anolobine as potential inhibitors of dual specificity protein kinase CLK1
Published 2025-04-01“…Therefore, there is an urgent need for novel therapeutic interventions that offer improved effectiveness with fewer side effects. …”
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Gaming-Based Tele-Exercise Program to Improve Physical Function in Frail Older Adults: Feasibility Randomized Controlled Trial
Published 2024-11-01“…In the CogXergaming group, 15 (83%) completed the intervention, with 3 (16%) dropping out in the first week. …”
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508
Ginseng and its functional components in non-alcoholic fatty liver disease: therapeutic effects and multi-target pharmacological mechanisms
Published 2025-04-01“…Studies have shown that ginseng and its functional components have the ability to regulate lipid metabolism disorders, inflammation, oxidative stress, endoplasmic reticulum stress, insulin resistance, disruption of intestinal flora structure, cell death and senescence. …”
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509
Deciphering the secret codes in N7‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases
Published 2025-02-01“…As a pivotal m7G regulator, methyltransferase‐like 1 (METTL1) is responsible for methyl group transfer during the progression of m7G modification and contributes to the structure and functional regulation of RNA. Accumulating evidence in recent years has revealed that METTL1 plays key roles in various diseases depending on its m7G RNA methyltransferase activity. …”
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510
Effect of Muscle Strength on Functionality after Shoulder Tendon Transfer in Brachial Plexus Birth Injury: Is There a Relationship between Them?
Published 2024-09-01“…Comprehensive assessment methods are necessary to understand structural problems and to plan appropriate interventions in children with BPBI. …”
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Association of workplace support for health with occupational health literacy and illness avoidance: moderated mediation by functioning through a salutogenic lens
Published 2025-08-01“…Data were analysed with Hayes’ Process Model through structural equation modelling. Results WSH had a positive effect on functioning (β = 0.29; p < 0.001) and illness avoidance (β = 0.25; p < 0.001) in the whole sample. …”
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513
Feasibility, safety and preliminary effect of exercise prehabilitation in patients with esophageal cancer undergoing surgery: an open-label, randomized, parallel-group pilot and fe...
Published 2025-08-01“…However, evidence on structured exercise prehabilitation, specifically for functional recovery after esophagectomy, remains limited. …”
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514
Green volunteerism among higher education institution students in Malaysia: Insights from the Volunteer Functions Inventory and the Norm Activation Model
Published 2025-01-01“…This study addresses the limited research on the combined application of the Volunteer Functions Inventory (VFI) and the Norm Activation Model (NAM) to explain green volunteering intentions, particularly among youth in Southeast Asia. …”
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515
Life satisfaction in emerging adulthood: a longitudinal study of social support, resilience, and gender differences
Published 2025-07-01“…Psychological resilience was found to partially account for this association (indirect effect: β = 0.25, p < 0.001), suggesting that resilience may function as a linking factor between social support and subsequent wellbeing. …”
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516
Frozen Shoulder - Evaluating the Effectiveness of Physical Therapy against Other Interventions Like Corticosteroid Injections, Non-steroidal Anti-inflammatory Drugs (NSAIDs), and S...
Published 2025-03-01“…Physical therapy remains a cornerstone of treatment, particularly in the frozen and thawing stages, and is most effective when combined with other interventions. While corticosteroid injections demonstrate significant short-term benefits in pain relief and functional improvement, their efficacy diminishes over time unless supported by a structured rehabilitation program. …”
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Keeping Active with Texting after Stroke (KATS): a single-arm feasibility and acceptability study of a behavioural intervention to promote community-based physical activity after s...
Published 2025-02-01“…Semistructured interviews explored intervention acceptability. Preintervention and postintervention measures provided preliminary information on step count, functional independence, mental well-being, self-efficacy and quality of life.Results 18 men and 13 women were recruited; three withdrew before intervention commencement. …”
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518
Co-Creation to Increase Cross-Functional Collaboration in Police Investigations of Online Child Sexual Abuse: A Qualitative Study Protocol
Published 2025-04-01“…The project aims to: (1) identify challenges and potentials for cross-functional teamwork in online CSA investigations; (2) co-design a team-based intervention to address identified needs; and (3) evaluate the intervention’s impact on efficiency and organizational outcomes. …”
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519
Rethinking the distinction between job burnout and depression: the mediating role of stress among healthcare professionals in Ecuador
Published 2025-06-01“…Measurement invariance across gender was supported, although males and females exhibited different symptom patterns: Men reported more cognitive-affective symptoms, while women endorsed more somatic and concentration-motor features.ConclusionThese findings support the interpretation of job burnout as a potential work-related manifestation of depression, with psychological stress functioning as a transdiagnostic mechanism. From a public health perspective, interventions should target not only individual-level symptoms but also systemic occupational stressors that shape mental health outcomes among healthcare professionals.…”
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Role of physical activity in enhancing physical quality of life for stroke prevention
Published 2025-08-01“…Discussion: the findings aligned with existing literature indicating that structured physical activity reduces stroke risk and enhances physical well-being. the results also confirmed that these benefits are partly explained by improvements in cardiovascular function. …”
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