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421
The association between family function and adolescents’ non-suicidal self-injury behaviors—is Chinese culture involved?
Published 2025-08-01“…In the Chinese cultural context, where family structure and attitudes toward sexuality are unique, the link between family function and adolescent NSSI remains underexplored.MethodsThis cross-sectional study recruited 157 adolescent psychiatric patients (aged 13–18) from both outpatient and inpatient settings. …”
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422
The YoungFitT project: Study protocol for a randomized mixed-methods trial of physical exercise and mind-body interventions, with or without virtual reality, in university students...
Published 2025-01-01“…<h4>Discussion</h4>The proposed interventions are expected to produce differential effects on psychological well-being and cognitive function. …”
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423
Plastic but not progressive changes in cognitive function and hippocampal volume in an adolescent with bipolar disorder: a case report
Published 2025-01-01“…Initially, the individual exhibited impaired general cognitive function, as indicated by an IQ score of 80 on the Standard Raven’s Progressive Matrices test, and demonstrated slightly reduced bilateral hippocampal volume compared to the normative reference, as determined through quantitative structural magnetic resonance imaging (qsMRI). …”
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424
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A prospective study of cognitive impairment in Parkinson’s disease: clinical, neuropsychological, and neuroimaging correlates
Published 2025-06-01“…Conclusions: Cognitive impairment in PD is associated with advanced age, longer disease duration, metabolic factors, and structural brain changes. These findings suggest the potential for a predictive model to identify early cognitive decline in PD, enabling timely intervention and improved patient outcomes.…”
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426
Non-Invasive Diagnosis and Monitoring of Diabetic Nephropathy: Assessment of Renal Function and Fibrosis by Diffusion Kurtosis Imaging
Published 2025-07-01“…Among the DKI indicators, MK had the highest AUC (0.922, 95% CI: 0.843– 1.000).Conclusion: The noninvasive monitoring of DN was feasible with DKI, and MK could indicate the renal function and fibrosis of DN patients. Changes in MK may also serve as a biomarker to assess treatment response (eg, microstructural improvement) after therapeutic interventions (eg, drug therapy for diabetic nephropathy, anti-fibrotic therapy).Plain Language Summary: Diabetic nephropathy (DN) is a serious kidney complication of diabetes and the leading cause of end-stage renal disease. …”
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427
A diverse set of solubilized natural fibers drives structure-dependent metabolism and modulation of the human gut microbiota
Published 2025-05-01“…We performed a comprehensive structural characterization and functional evaluation of a unique and highly diverse set of new, highly soluble fibers with varied monosaccharide compositions, glycosidic linkages, and polymer lengths. …”
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428
Do executive functions and processing speed mediate the relationship between socioeconomic status and educational achievement? Analysis of an observational birth cohort study
Published 2024-12-01“…Children’s executive functions (including working memory and inhibition) and processing speed abilities may underlie these inequalities, however, the previous literature regarding this is limited. …”
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429
Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two DNA strands
Published 2025-03-01“…This comprehensive structural and functional study lays a foundation for rational enzyme redesign and potential applications in biotechnology.…”
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430
Development of a Structured Cooking Program for Clients at the Senior Care Centres: A Mix-Method Feasibility Study
Published 2025-02-01“…Participants demonstrated improvements in physical functions and community mobility immediately after the intervention and at a one-month follow-up. …”
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431
Effectiveness of a brief behavioural intervention on psychological distress among women with a history of gender-based violence in urban Kenya: A randomised clinical trial.
Published 2017-08-01“…No adverse events were attributable to the interventions or the trial. Limitations of the study include no long-term follow-up, reliance on self-report rather than structured interview data, and lack of an attention control condition.…”
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432
Martial Arts and ADHD: A Narrative Review of Cognitive, Behavioral, and Epigenetic Effects
Published 2025-05-01“…The findings indicate that martial arts interventions were associated with improvements in attention, working memory, and inhibitory control, particularly in structured disciplines such as judo and taekwondo. …”
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433
Curcumin Combined with Aerobic Exercise Improved Liver Function in Rats with Non-alcoholic Fatty Liver Disease
Published 2025-05-01“…Conclusion: Curcumin and/or aerobic exercise intervention could improve liver structure and function in NAFLD rats by moderately enhancing cellular autophagy through the regulation of the AMPK/mTOR signaling pathway. …”
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434
A quasi-experimental investigation of scapular stabilization exercises on muscle coordination and functional recovery in scapular dyskinesia
Published 2025-08-01“…Results: Post-intervention analysis showed significant improvements in scapular position and functional performance, with a statistically significant reduction in SPADI scores (p < 0.001). …”
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435
Mitochondrial Quality Control in Health and Disease
Published 2025-08-01“…Mitochondrial quality control (MQC) encompasses a coordinated network of mitochondrial biogenesis, dynamics (fusion and fission), and selective autophagy (mitophagy), which together sustain mitochondrial structure and function. Under physiological conditions, MQC ensures the removal of dysfunctional mitochondria, restricts excessive reactive oxygen species production, and modulates apoptosis, thereby supporting the high energy demands of organs such as the heart and brain. …”
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436
SS-31 Targets NOS2 to Enhance Osteogenic Differentiation in Aged BMSCs by Restoring Mitochondrial Function
Published 2025-12-01“…Additionally, SS-31 reduced NOS2 expression by 50%, highlighting its therapeutic potential in age-related bone loss. SS-31 intervention not only normalizes mitochondrial structure and function, reducing ROS levels and enhancing oxygen consumption rates, but also targets the NOS2 gene, a potential drug target, which upon knockdown, leads to a substantial upregulation of osteogenic markers and an improvement in mitochondrial function. …”
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437
Functional limitations and coping mechanisms of women aged 60 years and older with self-reported hand osteoarthritis
Published 2014-11-01“…Background: Hand osteoarthritis (HOA) is common in older women who seem to cope with the associated limitations in hand function. The importance of identifying coping mechanisms within a local context might have implications for intervention, especially with the introduction of National Health Insurance. …”
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438
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Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels
Published 2025-01-01“…Studies have shown that APOE ɛ4 mediates the modulation of intrinsic functional brain networks in cognitively normal individuals and significantly disrupts the whole-brain topological structure in AD patients. …”
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440