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201
Structural insights into terminal arabinosylation of mycobacterial cell wall arabinan
Published 2025-04-01“…A critical factor in Mtb’s pathogenicity is its intricate cell envelope, which acts as a formidable barrier against immune defences and pharmacological interventions. Central to this envelope are arabinogalactan (AG) and lipoarabinomannan (LAM), two complex polysaccharides containing arabinan domains essential for maintaining cell wall structure and function. …”
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202
User-Driven Development of a Digital Behavioral Intervention for Chronic Pain: Multimethod Multiphase Study
Published 2025-07-01“…For many, pain significantly impairs quality of life and everyday functioning. Behavioral interventions have shown utility, but access remains limited. …”
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203
Structural insights into Beclin 1 interactions with it's regulators for autophagy modulation
Published 2025-01-01“…Since the network can only be traced through structural data, such insights are essential. However, identifying the critical structural and conformational determinants facilitating signalling cascades remains a major challenge for protein-protein interactions (PPIs) based therapeutic interventions. …”
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204
Occupational Therapy Interventions and Their Impact on Work Performance and Activities of Daily Living in Persons with Multiple Sclerosis
Published 2024-12-01“…Occupational therapy (OT) plays an important role in managing MS by providing interventions designed to improve functional performance, promote independence, and enhance overall well-being. …”
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205
Mitigating riparian buffer zone degradation through policy interventions and learnings from best practices
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206
A Systematic Review of Hospital-to-School Reintegration Interventions for Children and Youth with Acquired Brain Injury.
Published 2015-01-01“…We selected articles for inclusion that report on studies involving: a clinical population with ABI; sample had an average age of 20 years or younger; an intentional structured intervention affecting hospital-to-school transitions or related components; an experimental design; and a statistically evaluated health outcome. …”
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207
Structural insights and biological activities of flavonoids: Implications for novel applications
Published 2025-01-01“…Notably, the physicochemical properties and functionalities of flavonoids are structurally dependent. …”
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208
Nutritional interventions in muscle hypertrophy research: a scientometric analysis within the context of resistance training (1992–2025)
Published 2025-08-01“…Results The results indicate that: (1) the combination of protein supplementation and resistance training represents the most prominent intervention strategy; (2) a stable tripartite research model has emerged, centering on the interaction among training, nutrition, and structural adaptation; (3) the thematic focus has gradually shifted from molecular mechanisms toward practical applications, emphasizing issues such as aging and functional improvement; and (4) notable research gaps remain, particularly the underrepresentation of women and Asian populations, insufficient attention to recovery, metabolism, and periodized nutrition, and the lack of a systematic framework for individualized interventions. …”
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209
High-resistance inspiratory muscle strength training: a promising strategy for improving vascular health in chronic kidney disease
Published 2025-04-01“…Impaired vascular health in CKD is characterized by both functional and structural alterations to the vasculature including hypertension, arterial stiffness, vascular endothelial dysfunction, and autonomic dysfunction. …”
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210
Noninvasive Strategies to Promote Functional Recovery after Stroke
Published 2013-01-01“…In the last few years, brain stimulation, mirror therapy, action observation, or mental practice with motor imagery has emerged as interesting options as add-on interventions to standard physical therapies. The neural bases for poststroke recovery rely on the concept of plasticity, namely, the ability of central nervous system cells to modify their structure and function in response to external stimuli. …”
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211
Research progress in retinal structural alterations in patients with mental disorders
Published 2025-02-01“…Given the overlapping pathophysiological mechanisms between neurodegenerative diseases and mental disorders, studying the structural and functional changes in the inner layers of the retina has emerged as a new direction in mental health research. …”
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212
THE CONCEPT OF A COMPREHENSIVE PROGNOSTIC MODEL OF THE EFFECTIVENESS OF IMPLEMENTATION OF MINIMALLY INVASIVE INTERVENTIONS IN THE TREATMENT OF CARIOUS PATHOLOGY
Published 2021-06-01“… The research presents a prognostic model of the effectiveness of minimally invasive interventions in the dental patients’ treatment of carious pathology, which was developed to reduce the impact of iatrogenic interventions, increase the results of biological, biomechanical and financial feasibility of treatment. …”
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213
Extracorporeal Circulatory Factors and Cerebral Functions in Operated Patients
Published 2009-04-01“…Acute global brain ischemia (AGBI), as a consequence of negative EC factors, was shown to have impact on cerebral, specifically, higher psychic functions. There was a heterogeneous susceptibility of cerebral structures to AGBI, particularly the structures of the left hemisphere and cerebellum. …”
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214
Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation
Published 2025-01-01“… Functional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle. …”
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215
Distribution of hand function by age in individuals with Rett syndrome
Published 2023-09-01“…Method We conducted a longitudinal study of 946 girls and young women with typical RTT seen between 2006 and 2021 in the US Natural History Study (NHS) featuring a structured clinical evaluation to assess the level of hand function skills. …”
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216
Functional outcome of surgical management of Bimalleolar ankle fractures
Published 2025-01-01“…Background: Bimalleolar fractures of the ankle are complex injuries that involve both bone and ligamentous structures, affecting joint stability and function. …”
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217
Impact of Lifestyle Intervention on HDL-Induced eNOS Activation and Cholesterol Efflux Capacity in Obese Adolescent
Published 2016-01-01“…A correlation between change in eNOS-Ser1177 phosphorylation or RCT and change in endothelial function was noted. Conclusion. A structured lifestyle intervention program improves antiatherosclerotic HDL functions, thereby positively influencing endothelial function.…”
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218
Evolving perspectives on aortic stenosis: the increasing importance of evaluating the right ventricle before aortic valve intervention
Published 2025-01-01“…However, progressive pressure overload in AS can initiate a cascade of extra-valvular myocardial remodeling that could also precipitate maladaptive alterations in the structure and function of the right ventricle (RV). …”
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219
Physiological and morphological impact of physical activity and nutritional interventions to offset disuse-induced skeletal muscle atrophy
Published 2025-04-01“…Skeletal muscle tissue acts as a functional unit for physical movements, energy metabolism, thermogenesis, and metabolic homeostasis. …”
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220
Physical activity interventions to improve cognition in first-episode psychosis: What we know so far
Published 2024-01-01“…They all analyzed the effect of structured physical activity interventions on the cognitive functioning of patients with FEP. …”
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