Comparing The Viral Load of Severe Acute Respiratory Syndrome Coronavirus 2 in Different Human Specimens by Ali Hattem Hussain

“…The sputum was positive up to 23 days in a daily manner since start of symptoms except for the days 19, 21, and 23 that were negative for the virus. …”
Get full text

Complementary feeding and the early origins of obesity risk: a study protocol by Daniel D Reidpath, Ireneous N Soyiri, Naleena Devi Muniandy, Pascale A Allotey

“…The assessment will occur around the time complementary feeding is expected to start (7 Months) and again at 12 months. A 24-hour diet recall and a 2-day food diary will be used to assess the food intake. …”
Get full text

The assembly factor Reh1 is released from the ribosome during its initial round of translation by Sharmishtha Musalgaonkar, James N. Yelland, Ruta Chitale, Shilpa Rao, Hakan Ozadam, David W. Taylor, Can Cenik, Arlen W. Johnson

“…Using selective ribosome profiling, we found that Reh1-bound ribosomes populate open reading frames near start codons. Reh1-bound ribosomes are also strongly enriched for initiator tRNA, indicating they are associated with early elongation. …”
Get full text

4d N $$ \mathcal{N} $$ = 1 from 6d D-type N $$ \mathcal{N} $$ = (1, 0) by Jin Chen, Babak Haghighat, Shuwei Liu, Marcus Sperling

“…Our approach is two-fold. We start by compactifying the 6d SCFT on a Riemann surface and compute the central charges of the resulting 4d theory by integrating the 6d anomaly polynomial over the Riemann surface. …”
Get full text

A global open-source dataset of monthly irrigated and rainfed cropped areas (MIRCA-OS) for the 21st century by Endalkachew Abebe Kebede, Kevin Ong’are Oluoch, Stefan Siebert, Piyush Mehta, Sarah Hartman, Jonas Jägermeyr, Deepak Ray, Tariq Ali, Kate A. Brauman, Qinyu Deng, Wei Xie, Kyle Frankel Davis

“…Here we construct a new data library of subnational crop-specific irrigated and rainfed harvested area statistics and combine it with global gridded land cover products to develop a global gridded (5-arcminute) irrigated and rainfed cropped area (MIRCA-OS) dataset for the years 2000 to 2015 for 23 crop classes. …”
Get full text

Importance of the 5’ untranslated region for recombinant enzyme production in isolated Bacillus subtilis 007 by Jana Senger, Adriana Schulz, Ines Seitl, Martin Heider, Lutz Fischer

“…Modifications on the PaprE core promoter region or the spacer, the sequence between the Shine-Dalgarno sequence and the start codon, did not improve β-galactosidase production. …”
Get full text

Step-by-step causal analysis of EHRs to ground decision-making. by Matthieu Doutreligne, Tristan Struja, Judith Abecassis, Claire Morgand, Leo Anthony Celi, Gaël Varoquaux

“…The first step is study design, using the target trial concept and the PICOT framework: Population (patients with sepsis), Intervention (combination of crystalloids and albumin for fluid resuscitation), Control (crystalloids only), Outcome (28-day mortality), Time (intervention start within 24h of admission). We show that too large treatment-initiation times induce immortal time bias. …”
Get full text

Scopus Indexing Delays of Articles Published in Major Pharmacy Practice Journals by Samuel Adeosun

“…Objective: The goal of this study was to determine the indexing delays in Scopus following online publication, to provide evidence-based recommendations for when data collection in Scopus should start after the end of the period-of-interest. …”
Get full text

Application of Shear-Wave Elastography in the Evaluation of Hamstring Stiffness in Young Basketball Athletes by Paige Cummings, Nathan D. Schilaty, Takashi Nagai, Luca Rigamonti, Ryo Ueno, Nathaniel A. Bates

“… # Methods Six-hundred forty-two lower extremities from 321 high school and collegiate basketball athletes (177 F: 139 M) were examined for hamstring stiffness prior to the start of their competitive basketball season. Teams were cluster assigned to either the control or intervention (TNMT) group. …”
Get full text

Discovery of Metal-poor and Distant Pre–Main Sequence Candidates in WLM with JWST by Venu M. Kalari, Ricardo Salinas, Morten Andersen, Guido De Marchi, Monica Rubio, Jorick S. Vink, Hans Zinnecker

Get full text

Management of volume load for patients undergoing hemodialysis via WeChat and home monitoring in China: a protocol for a cluster-randomized trial by Xiaocui Wang, Bonan Yan, Shipeng Zhang, Yuanke Zhou, Qinxiu Zhang, Xueying Li

“…Data will be collected during the baseline period, one, two, and three months after the intervention starts, and three months after the intervention ends to evaluate the effectiveness of this intervention measure. …”
Get full text

Environmental Disinfection Based on Mobile Intelligent Networking Highly Efficient Ultraviolet Light Machines by Chun-Yen Chung, Wen-Tsai Sung, Lin-Chi Wang, Lailatus Siami, John Paul Santos

“…In addition to manually controlling the sterilizer, a Wi-Fi or Narrowband (NB)-IoT-enabled remote control was provided to start the disinfection process. In order to prevent ultraviolet light from harming the human body, sensors were employed self-acting to detect the presence of people and turn off the ultraviolet light when people were detected in the area. …”
Get full text

A Refined Astrometric Approach Based on the Precision Premium and its Application to the Jupiter’s Satellite Himalia by Z. J. Zheng, Q. Y. Peng, F. R. Lin, D. Li

Get full text

Dexamethasone in Treatment of Comorbid SARS-CoV-2 Patients Aged over 50 Years with Lung Injury over 50 % by O. Yu. Zolnikova, R. V. Maslennikov, V. T. Ivashkin, N. L. Dzhakhaya, O. Yu. Kiseleva, N. D. Potskhverashvili, S. A. Shorokhova

“…Dexamethasone therapy 4–12 mg/day in SARS-CoV-2 patients aged 50+ years with grade 3–4 CT changes receiving LMWH from start of hospitalisation significantly improved CT scores and reduced mortality.…”
Get full text

Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology Assessment Programme by Stephen J Walters, Daniel Hind, Richard M Jacques, Steven A Julious, Joanne Rothwell, Oscar Bortolami, Laura Flight, Inês Bonacho dos Anjos Henriques-Cadby, Christopher Knox, Ben Nadin, Michael Surtees

“…Many trials fail to reach their planned sample size within the envisaged trial timescale and trial funding envelope.Objectives To review the consent, recruitment and retention rates for single and multicentre randomised control trials funded and published by the UK's National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme.Data sources and study selection HTA reports of individually randomised single or multicentre RCTs published from the start of 2004 to the end of April 2016 were reviewed.Data extraction Information was extracted, relating to the trial characteristics, sample size, recruitment and retention by two independent reviewers.Main outcome measures Target sample size and whether it was achieved; recruitment rates (number of participants recruited per centre per month) and retention rates (randomised participants retained and assessed with valid primary outcome data).Results This review identified 151 individually RCTs from 787 NIHR HTA reports. …”
Get full text

Analysis of fermentation characteristics in fermented grains across seven rounds of sauce-flavored Baijiu: Microbial communities structure, physicochemical parameters, volatile and... by Xiaomin Liu, Yingchun Mu, Xiangxiang Lv, Nuo Chen, Lei Chen, Tangzheng Wen, Wei Su

“…This study aimed to elucidate the fermentation characteristics in fermented grains at the start (EP) and at the end (OP) of pit fermentation across seven rounds of SFB. …”
Get full text

Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies. by Peter R McIlroy, Le Thanh Mai Pham, Thomas Sheffield, Maxwell A Stefan, Christine E Thatcher, James Jaryenneh, Jennifer L Schwedler, Anupama Sinha, Christopher A Sumner, Iris K A Jones, Stephen Won, Ryan C Bruneau, Dina R Weilhammer, Zhuoming Liu, Sean Whelan, Oscar A Negrete, Kenneth L Sale, Brooke Harmon

“…In this study, we used a combination of high throughput screening and machine learning (ML) models to identify HCAbs with potent efficacy against SARS-CoV-2 viral variants of interest (VOIs) and concern (VOCs). To start, we screened our highly diverse Nb phage display library against several pre-Omicron VOI and VOC receptor binding domains (RBDs) to identify panels of cross-reactive HCAbs. …”
Get full text

SYMBOLIC ANALYSIS OF CLASSICAL NEURAL NETWORKS FOR DEEP LEARNING by Vladimir Milićević, Igor Franc, Maja Lutovac Banduka, Nemanja Zdravković, Nikola Dimitrijević

“…In this paper, we propose, as a proof of concept, to start the system design by drawing a single neuron. …”
Get full text

Partitioning the phenotypic and genetic variances of reaction norms by de Villemereuil, Pierre, Chevin, Luis-Miguel

“…Here, we propose a partitioning of phenotypic variance across genotypes and environments that jointly address these challenges. We start by distinguishing the components of phenotypic variance arising from the average reaction norm across genotypes, genetic variation in reaction norms (with additive and non-additive components), and a residual that cannot be predicted from the genotype and the environment. …”
Get full text

Digital twin of a large-aspect-ratio Rayleigh–Bénard experiment: role of thermal boundary conditions, measurement errors and uncertainties by Philipp P. Vieweg, Theo Käufer, Christian Cierpka, Jörg Schumacher

“…This study traces these discrepancies back to their origins. We start by generating a digital twin of one standard experimental set-up. …”
Get full text