Hypertension moderates the relationship between plasma beta-amyloid and cognitive impairment: a cross-sectional study in Xi’an, China by Ziyu Liu, Yaoli He, Simeng Cui, Liangjun Dang, Binyan Zhang, Jin Wang, Wenhui Lu, Kang Huo, Yu Jiang, Chen Chen, Ling Gao, Shan Wei, Yi Zhao, Ningwei Hu, Jingyi Wang, Hong Lv, Hong Lv, Qiumin Qu, Qiumin Qu, Suhang Shang

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Thrombolytic therapy for patients with acute ischemic stroke: systematic review and network meta-analysis of randomized trials by Li-Chao-Yue Sun, Wen-Shu Li, Wei Chen, Zhao Ren, Chun-Xing Li, Ze Jiang, Le Wang, De-Li Wang, Qing Xie

“…For safety outcomes, 0.25 mg/kg tenecteplase had lower incidences of symptomatic intracranial hemorrhage (OR 0.88, 95% CI: 0.35–1.8), death within 90 days (OR 0.91, 95% CI: 0.54–1.4), and serious adverse events (OR 1.0, 95% CI: 0.47–2.3) compared to alteplase, though differences were not statistically significant. Reteplase at 18 mg + 18 mg had higher incidences of death within 90 days (OR 1.2, 95% CI: 0.48–3) and serious adverse events (OR 1.4, 95% CI: 0.4–5.0) compared to alteplase, without significant differences. …”
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Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA19... by Liang Qi, Xiang Li, Jiayao Ni, Yali Du, Qing Gu, Baorui Liu, Jian He, Juan Du

“…We used short-term and long-term treatment efficacy as the prediction outcomes and performed statistical and machine learning-based feature selection and COX regression analysis to identify potentially predictive features. …”
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Examining Inclusive Tertiary Education Delivery through the National Open University of Nigeria's Community Study Centres by Musibau O. Oyebode

“…Using the survey method involving qualitative and quantitative approaches, the instruments of data collection included a set of Likert five scale questionnaire administered to 600 respondents and an interview guide conducted with 24 interviewees selected through snowball and purposive sampling techniques. Statistical records of enrolment, registration and graduation were also analysed for attrition rate. …”
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Comprehensive Evaluation of GPM-IMERG, CMORPH, and TMPA Precipitation Products with Gauged Rainfall over Mainland China by Guanghua Wei, Haishen Lü, Wade T. Crow, Yonghua Zhu, Jianqun Wang, Jianbin Su

“…Categorical verification techniques and statistical methods are used to quantify their performance. …”
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Novel type 2 diabetes prediction score based on traditional risk factors and circulating metabolites: model derivation and validation in two large cohort studiesResearch in context by Ruijie Xie, Christian Herder, Sha Sha, Lei Peng, Hermann Brenner, Ben Schöttker

“…External validation in the ESTHER cohort showed a comparable statistically significant C-index increase from 0.770 (0.750, 0.791) to 0.798 (0.779, 0.817) and a continuous NRI of 33.8% (26.4%, 41.2%). …”
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Pratiques de l’automédication à l’ère de la pandémie COVID-19 dans trois villes de l’Ouest algérien [Practices of self-medication in the COVID-19 pandemic era in three cities of We... by Derouicha Matmou, Asma Memou, Yassine Merad, Ayoub Bouzid, Sohaïb Abd-El-Koudous Bouzid, Aissa Brik, Mounia Sakouhi

“…The main endpoint was the evaluation of­self-medication practices. Data entry, statistical analysis and editing of results were perfor­med using SPSS software version 20. …”
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The value of 18F⁃FDG PET in the diagnosis and differential diagnosis of Parkinson's disease and multiple system atrophy with parkinsonism⁃predominant by DU Xiao‐xiao, DONG Wan‐hui, LI Yi, SUN Zhi‐hui, FAN Kang‐li, ZHANG Ying

“…The ROC curve was drew for the differential diagnostic efficacy of 18F⁃FDG PET through the six brain regions with statistical difference and P = 0.000 between the 2 groups, the result showed that the AUC of cerebellum (Z = 3.595, P = 0.000; Z = 2.942, P = 0.003; Z = 2.942, P = 0.003; Z = 3.519, P = 0.000), pons (Z = 3.363, P = 0.001; Z = 3.237, P = 0.000; Z = 2.376, P = 0.018; Z = 3.012, P = 0.003) and the combination of the six brain regions (Z = 4.354, P = 0.000; Z = 4.242, P = 0.000; Z = 3.711, P = 0.000; Z = 4.233, P = 0.000) were bigger than the AUC of precuneus, superior parietal, inferior parietal and lateral occipital; the AUC of the combination of the six brain regions was bigger than pons (Z = 1.986, P = 0.047). …”
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Ultrafast dynamic contrast-enhanced breast MRI with quantitative perfusion parameters in differentiating breast cancer: a study focusing on triple-negative and HER2 positive breast... by Guo Haodong, Zhu Jianguo, Dmytro Pylypenko, Dou Weiqiang, Su Sheng, Xu Jie, Li Haige

“…TNBC versus non-TNBC revealed statistical variations in quantitative parameters (Ktrans: 1.03 min-1 vs. 0.15 min-1, kep: 0.61 min-1 vs. 0.19 min-1, vp: 0.18 vs. 0.01, all P < 0.05). …”
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Application effect of Zhulianhua Gargle in oral care of inpatients with hyperthermia syndrome (竹连花含漱液在实热证住院患者口腔护理中的应用效果) by HAO Tiantian (郝天天), WEI Jinrong (魏金荣), ZHANG Lingyan (张玲燕), QIU Shuang (邱爽), ZHAO Wei (赵伟), GENG Tong (耿桐)

“…After 2 weeks of intervention, patients in the observation group achieved better outcomes in oral pH value (6. 23±0. 52), oral function score (8. 71±4. 05), halitosis value score (1. 29±0. 61) and oral comfort rate of the observation group(100. 00%), and he difference between the two groups was statistically significant (P＜0. 05). Conclusion Zhulianhua Gargle has a good effect on improving the oral syndrome of hyperthermia, improving oral pH value, oral function, making oral freshness and improving oral comfort. …”
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New proposal for a multimodal imaging approach for the subclinical detection of hydroxychloroquine-induced retinal toxicity in patients with systemic lupus erythematosus by Ricard Cervera, Alfredo Adan, Gerard Espinosa, Jose Rios, Olga Araujo, José Hernández-Rodríguez, Laura Pelegrín, Ricardo P Casaroli-Marano, Halbert Hernández-Negrín, Marc Figueras-Roca, Vanesa Budi, Montse Morató

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COVID-19 in discharged patients with diabetes and chronic kidney disease: one-year follow-up and evaluation by Enrong Ran, Enrong Ran, Yutong Zou, Chuanyi Zhao, Kai Liu, Jiamin Yuan, Wenjie Yang, Lijun Zhao, Qing Yang, Jia Yang, Xuegui Ju, Linli Cai, Yanlin Lang, Xingyuan Li, Ke Liu, Fang Liu, Fang Liu

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Food insecurity and the risk of HIV acquisition: findings from population-based surveys in six sub-Saharan African countries (2016–2017) by Danielle Barradas, Nicholus Mutenda, Hetal Patel, Avi J Hakim, Lloyd Mulenga, Sally Findley, Andrea Low, George Rutherford, Sarah Ayton, Elizabeth Gummerson, Amee Schwitters, Rogerio Bonifacio, Mekleet Teferi, James Juma, Claudia Ahpoe, Choice Ginindza, Samuel Biraro, Karam Sachathep, Ahmed Saadani Hassani, Willford Kirungi, Keisha Jackson, Leah Goeke, Neena Philips, Jennifer Ward, Steven Hong

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A retrospective analysis of outcomes and complications of living- and deceased-donor split-liver transplantation in Johannesburg, South Africa by R Crawford, J Loveland, P Gaylard, J Fabian, K Kinandu, B Bobat, A Mahomed, D Parbhoo, M Beretta, S Berkenfeld, S Rambarran, F van der Schyff, L Brannigan, B Strobele

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Significance of changes in levels of neutrophil extracellular traps during development of silicosis in mice by Lu HAN, Ruru CHEN, Yulu XIONG, Ziye GUO, Hailan HE, Xiaohui HAO, Heliang LIU, Lingli GUO

“…Compared with the control group (7.434±0.258) ng·mL−1, the ex-DNA levels in BALF of mice in the 2 d [(35.110±6.331) ng·mL−1], the 7 d [(39.491±6.948) ng·mL−1], and the 28 d [(23.360±4.809) ng·mL−1] model groups were increased (P<0.05), and the increase of ex-DNA in the 2 d and the 7 d model groups were statistically significant (P<0.05). In comparison with the control group, the protein level of CitH3 was significantly increased in the lung tissues of mice in the 7 d model group (P<0.05). …”
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Exploration of rituximab treatment strategies for membranous nephropathy adapted to the Chinese healthcare environment by Xiaolong Wang, Xueying Cao, Jie Wu, Shuang Liang, Jian Yang, Hong Wang

“…Among these patients, 59.5% (75/126) received RTX combined with GCs and/or IMS. Statistical results revealed that the combined use of GCs and/or the IMS had no significant effect on renal remission (P = 0.439), but it accelerated the process of renal remission (P = 0.010). …”
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Perbedaan Rerata Kadar Profil Lipid pada Preeklampsia dengan Kehamilan Normal pada Etnik Minangkabau by Helen Evelina Siringoringo, Yusrawati ., Eva Chundrayetti Chundrayetti

“…The data analyzed statistically by independent t-test. The result of this study showed mean level of total cholesterol in preeclamsia and normal pregnancy were 270.19±68.955 mg/dL and 247.56±44.415 mg/dL with p-value 0.158. …”
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The Combined Effect of Garlic (Allium sativum) and Turmeric (Curcuma longa) Extracts to Reduce the Adverse Effects of Aflatoxin B1 in Rats by Hadi Sarir, Saeedeh Zakerian, masood didarkhah

“…In examining the ALP factor, there was a statistically significant difference between the treatments of garlic or turmeric extract and the combination of these two extracts. …”
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Observation on the curative effect of umbilicus application therapy combined with Cucurbit moxibustion in the treatment of spleen deficiency syndrome of type 2 diabetes mellitus (敷... by GAO Junluan (高俊娈), XUE li (薛丽), ZHANG Gengliang (张庚良), HAO Min (郝民), MAO Hui (毛慧), SHEN Yanru (沈彦如)

“…Results There were statistically significant differences in spleen deficiency symptom score, fasting blood glucose (FBG) and 2-hour postprandial blood glucose (2hPBG) before and after treatment (P<0. 05). …”
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Renal dysfunction contributes to deteriorated survival outcomes in patients with upper and lower gastrointestinal bleeding: insights from a cohort study of 1160 cases by Orsolya Anna Simon, Levente Frim, Nelli Farkas, Zoltán Sipos, Nóra Vörhendi, Eszter Boros, Dániel Pálinkás, Brigitta Teutsch, Patrícia Kalló, Vivien Vass, Andrea Szentesi, Roland Hágendorn, Péter Hegyi, Bálint Erőss, Imre Szabó

“…Numerous primary (in-hospital mortality, discharge, need for endoscopic intervention, in-hospital rebleeding, length of hospitalisation, need for emergency surgery, need for endoscopic examination and need for intensive care unit) and secondary (detection of Helicobacter pylori (H. pylori), recognition of cancer as the source of bleeding, need for any kind of transfusion or clotting factor, anticoagulation therapy) outcomes were observed. Descriptive statistical tools were used to summarize our data. Among others, estimated glomerular filtration rate (eGFR) (ml/min/1.73 m2) was used as continuous variable, mean, standard deviation, median, interquartile range and minimum/maximum values were calculated. …”
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