Effects of Bedaquiline on Antimicrobial Activity and Cytokine Secretion of Macrophages Infected with Multidrug-Resistant Mycobacterium tuberculosis Strains by Xia-Li Lyu, Ting-Ting Lin, Jing-Tao Gao, Hong-Yan Jia, Chuan-Zhi Zhu, Zi-Hui Li, Jing Dong, Qi Sun, Wei Shu, Sai-Sai Wang, Li-Ping Pan, Hai-Rong Huang, Zong-De Zhang, Qi Li

“…Normally distributed continuous data (mean ± standard deviation) were analyzed using t-test or F-test (SPSS 25.0, P<0.05 deemed statistically significant). Results. (1) 100% of Bdq-treated macrophages (all doses applied over 4–48 h) survived with 0% inhibition of proliferation observed. (2) Intracellular CFUs of Bdq-treated MDR-MTBs-infected macrophages decreased over 4–48 h of treatment, were lower than preadministration and control CFUs, decreased with increasing Bdq dose, and resembled H37Rv-infected group CFUs (48 h). (3) For MDR-MTBs-infected macrophages (various Bdq doses), IL-12/23 p40 levels resembled preadministration group levels and exceeded controls (4 h); TNF-α levels exceeded preadministration group levels (24 h/48 h) and controls (24 h); IL-12/23 p40 and TNF-α levels resembled H37Rv-infected group levels (4 h/8 h/24 h/48 h); IL-6 levels exceeded preadministration and H37Rv-infected group levels (24 h/48 h) and controls (24 h); IL-10 levels resembled preadministration and H37Rv-infected group levels (4 h/8 h/24 h/48 h) and were lower than controls (24 h/48 h); IL-12/23 p40 and IL-10 levels remained unchanged as intracellular CFUs changed, with IL-12/23 p40 levels exceeding controls (4 h) and IL-10 levels remaining lower than controls (24 h/48 h); TNF-α and IL-6 levels increased as intracellular CFUs decreased (24 h/48 h) and exceed controls (24 h). …”
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Three-dimensional omnidirectional characterization methods of rock anisotropic wave velocity and acoustic emission location optimization by Shengjun MIAO, Wenxuan YU, Mingchun LIANG, Pengjin YANG, Conghao LI, Zejing LIU

“…In the damage stage, the minimum wave velocity decreases due to rock damage and crack formation, whereas the maximum wave velocity remains unaffected. The statistical results indicate that the azimuth of the wave velocity ellipsoid for marble and siltstone is over 77% consistent with the crack azimuth. …”
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Disproportionate Distribution of HBV Genotypes A and D and the Recombinant Genotype D/E in the High and Low HBV Endemic Regions of Uganda: A Wake-Up Call for Regional Specific HBV... by Hussein Mukasa Kafeero, Dorothy Ndagire, Ponsiano Ocama, Charles Drago Kato, Eddie Wampande, Henry Kajumbula, David Kateete, Abdul Walusansa, Ali Kudamba, Kigozi Edgar, Fred Ashaba Katabazi, Maria Magdalene Namaganda, Jamilu E. Ssenku, Hakim Sendagire

“…A p<0.05 was considered statistically significant. Results. Majority of our study subjects were female (64.5%), youth (51.0%), and married (62.0%). …”
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A community-based study to assess the prevalence and predictors of stunting among under-five children in Sheger City, Oromia, Ethiopia by Firomsa Botorie, Bilisom Balcha Abera, Abera Botorie, Abera Botorie, Asonya Abera, Abebe Dukessa Dubiwak, Abebe Dukessa Dubiwak, Tesfaye Getachew Charkos, Godana Arero Dassie

“…A p-value of &lt;0.05 was considered statistically significant. The goodness-of-fit for the model was assessed using the Hosmer-Lemeshow test.ResultsThe prevalence of stunting was 18.9% (95% CI: 16, 22%) among under-five children in our study setting. …”
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The hidden crisis: double burden of malnutrition among refugee children in South Asia – a systematic review and meta-analysis from observational studies by Pooja Panchal, Mohd Usman, Tajung Longkumer, Reshma Susan Babu, Mahalaqua Nazil Khatib, Shariza Abdul Razak, Kavitha Menon

“…The gray literature was manually searched from the reputed organizations focusing on refugee children and was narratively analyzed for malnutrition statistics. Furthermore, the corroboration of primary research articles and gray literature was conducted for comprehensive understanding.ResultsThe review included 10 full-text research articles, all with cross-sectional study design and 11 gray literatures. …”
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Efek Pemberian Vitamin C Terhadap Aktifitas Katalase Hati Tikus Galur Wistar yang Terpapar Ion Pb by Elmatris Sy, Husnil Kadri, Eti Yerizel

“…Administration of vitamin C were exposed to Pb ion statistically by one-way ANOVA test there was no significant effect ( p = 0.143 or p &gt; 0.05 ) . …”
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The Effect of Dynamic Service Innovation Capabilities on Firm Performance: The Moderating Role of Perceived Environmental Dynamism and the Mediating Role of Service Innovation and... by Rasoul Nosratpanah, Samad Barani, Aref Ashrafzadeh, Gholamhosein Atashi

“…Therefore, this research aims to investigate the impact of dynamic service innovation capabilities on firm performance by explaining the moderating role of perceived environmental dynamics and the mediating role of service innovation and competitive advantage.MethodologyThe research employs an applied purpose and a descriptive-correlational nature. The statistical population for this research comprises hotel managers. …”
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Duration of External Neck Stabilisation (DENS) following odontoid fracture in older or frail adults: protocol for a randomised controlled trial of collar versus no collar by John Norrie, Julie Woodfield, David J Lowe, Paul M Brennan, Catriona Keerie, Julia Lawton, Matthew J Reed, Andrew Stoddart, Julia Boyd, Helen Eborall, Gina Cranswick, James Tomlinson, Polly L Black, Sadaquate Khan, Patrick Statham, Ellie Edlmann, Phillip Correia Copley, Angela Niven, Susan Deborah Shenkin

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Designing a Model for Demand Side Management in Electricity Sector Based on Collaborative Governance by Gholamreza kazemian, Mohammadreza Raecy, Reza Vaezi, Vajollah Ghorbanizadeh

“…The sample comprised 198 individuals, determined as statistically significant according to the Cochran formula, with participants chosen via simple random sampling. …”
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Diagnostic Accuracy of Non-Invasive Diagnostic Tests for Nonalcoholic Fatty Liver Disease: A Systematic Review and Network Meta-Analysis by Sun Y, Hu D, Yu M, Liang SB, Zheng Y, Wang X, Tong G

“…The participants included patients with suspected or confirmed NAFLD, irrespective of age, sex, ethnicity. Statistical analysis was conducted using R 4.0.3 for Bayesian NMA and STATA 17.0 for pairwise meta-analysis. …”
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Association between Corneal Stiffness Parameter at the First Applanation and Keratoconus Severity by Kaili Yang, Liyan Xu, Qi Fan, Shengwei Ren

“…SP-A1 was found to be statistically positively associated with intraocular pressure (IOP), biomechanical corrected IOP (bIOP), time from the initiation of air puff until the first applanation (A1T), corneal velocity at the second applanation (A2V), and negatively associated with deformation amplitude (DA), peak distance (PD), corneal velocity at the first applanation (A1V), time from the initiation of air puff until the second applanation (A2T), and DA Ratio Max [2 mm] both in normal and keratoconus eyes (all P<0.05). …”
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Comparing the Institution-based Supervision and Tele-based Supervision for Task-oriented Exercises on Upper Limb Motor Performance and Functional Ability among Stroke Patients: A R... by Neha, Subhasish Chatterjee

“…An Independent t-test or Mann-Whitney U-test will be applied based on normality to compare the changes in mean values of the outcome measures between Group A and Group B at baseline, the 4th week, and the 8th week of intervention. The level of statistical significance will be set at alpha=0.05.…”
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Associations of health literacy with metabolic status and quality of life among comunity patients with type 2 diabetes in Shanghai by YANG Liping, SONG Haihong, SHEN Jue, GAO Jinli, ZHANG Zhiping, QIAN Liuyu, GONG Huan

“…Similarly, significant differences were found in FPG achievement rates across different age groups, annual household incomes, disease durations, and family histories (P<0.05). No statistically significant differences were noted in TG and HDL-C achievement rates across all variables (P>0.05). …”
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Trends in certifications of overall vision impairment and that due to diabetic retinopathy/maculopathy in England and Wales, 2009/2010 to 2019/2020: a retrospective database analys... by Catey Bunce, Gwyn Samuel Williams, David Owens, Wen Xing, Rhianon Reynolds, Antra Zekite, Declan Flanagan, RL Thomas, Rebecca John

“…This rate subsequently increased to 51.8 per 100 000 by 2019/2020; however, this was not statistically significant (p=0.087). Individuals in Wales had a 9% higher certification rate compared with those in England (1.09 (95% CI 1.07, 1.10)). …”
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Uncovering women's healthcare access challenges in low- and middle-income countries using mixed effects modelling approach: Insights for achieving the Sustainable Development Goals... by Bewuketu Terefe, Belayneh Shetie Workneh, Gebreeyesus Abera Zeleke, Enyew Getaneh Mekonen, Alebachew Ferede Zegeye, Agazhe Aemro, Berhan Tekeba, Tadesse Tarik Tamir, Mulugeta Wassie, Mohammed Seid Ali

“…The Adjusted Odds Ratio (AOR) with a 95% Confidence Interval (CI) and a P value < 0.05 was reported to indicate statistical significance and the degree of association in the final model.…”
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Efficacy and Safety of Ultrasound-Guided Radiofrequency Treatment for Chronic Pain in Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis by Yuzhao Huang, Qiufang Deng, Liuqing Yang, Jiahui Ma, Ziyang Wang, Dong Huang, Ling Luo, Haocheng Zhou

“…Heterogeneity was assessed by I2 statistic and the potential sources of heterogeneity by subgroup and metaregression analyses, respectively. …”
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Molecular Data Confirm the Occurrence of the Allochthonous <i>Gambusia holbrooki</i> (Pisces: Poeciliidae) in Sicily and the Maltese Archipelago by Luca Vecchioni, Mirko Liuzzo, Arnold Sciberras, Jeffrey Sciberras, Justin Formosa, Alan Deidun, Gabriele Giacalone, Vincenzo Arizza, Marco Arculeo, Federico Marrone, Francesco Paolo Faraone

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Inflammatory Markers and Severity in COVID-19 Patients with Clostridioides Difficile Co-Infection: A Retrospective Analysis Including Subgroups with Diabetes, Cancer, and Elderly by Teodor Cerbulescu, Flavia Ignuta, Uma Shailendri Rayudu, Maliha Afra, Ovidiu Rosca, Adrian Vlad, Stana Loredana

“…Subgroup analyses included diabetes, elderly (≥65 years), and cancer patients. Statistical comparisons employed <i>t</i>-tests, chi-square tests, and logistic regression models. …”
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La répartition des chimpanzés à Sebitoli (Parc National de Kibale, Ouganda): influence des facteurs naturels et anthropiques by Sarah Bortolamiol, Marianne Cohen, Milena Palibrk, Sabrina Krief

“…It also resulted in statistical curves that describe the weight of each variable in the construction of the chimpanzee’s probability model.We determine the core area of the chimpanzees’s community (around 20 km2 with a more frequented area of 4.5 km2). …”
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Effectiveness of Different Intervention Modes in Lifestyle Intervention for the Prevention of Type 2 Diabetes and the Reversion to Normoglycemia in Adults With Prediabetes: Systema... by Yachen Wang, Xin Chai, Yueqing Wang, Xuejun Yin, Xinying Huang, Qiuhong Gong, Juan Zhang, Ruitai Shao, Guangwei Li

“…The overall intervention effect was synthesized using a random-effects model. The I² statistic was used to assess heterogeneity across the RCTs. …”
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