Large-scale data mining of four billion human antibody variable regions reveals convergence between therapeutic and natural antibodies that constrains search space for biologics dr... by Pawel Dudzic, Dawid Chomicz, Jarosław Kończak, Tadeusz Satława, Bartosz Janusz, Sonia Wrobel, Tomasz Gawłowski, Igor Jaszczyszyn, Weronika Bielska, Samuel Demharter, Roberto Spreafico, Lukas Schulte, Kyle Martin, Stephen R. Comeau, Konrad Krawczyk

“…Thus, the subspace of shared (‘public’) CDR-H3s shows utility for serving as a starting point for therapeutic antibody design.…”
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Case report: Diagnosis of impaired consciousness in a cancer patient using immune checkpoint inhibitors by Daniel Cathalifaud, Daniel Cathalifaud, Cristóbal Basáez, Tatiana Yáñez, Tatiana Yáñez

“…We present the case of a patient diagnosed with pleural mesothelioma that started combined palliative immunotherapy two months before admission. …”
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On Some Tendencies in Defense Policy of Germany by N. K. Meden

“…Officially it is deemed, that the reform of the Bundeswehr which started in 2011, so far has turned into an amorphous process of renewal (Neuausrichtung), intended to improve the military organization. …”
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Enhanced image processing and storage for defect evaluation in BIM of inspected steel bridges by Dogan Karluklu, Cecilia Rinaldi, Marianna Crognale, Lucia Figuli, Vincenzo Gattulli

“…The authors table a procedure that can be followed, starting with storing defect images and ending with defect visualization in the BIM environment, and present a discussion on the advantages and limits of the process by examining concepts such as automated data collection by drones, machine vision-based damage identification by color detection technique, BIM and Industry Foundation Classes standardisation applied to inspection data.…”
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A randomized double-blind active-controlled clinical trial on the efficacy of topical basil (Ocimum basilicum) oil in knee osteoarthritis by Alireza Askari, Fatemeh Sadat Hasheminasab, Fatemeh Sadat Hasheminasab, Omid Sadeghpour, Mohammad Mehdi Naghizadehd, Seyed Ali Ravansalar, Aida Iraji, Mohammad Hashem Hashempur

“…Various measurements were taken at the beginning of the study, 2, and 4 weeks after starting the intervention, including the 8-m walk test, knee pain (based on visual analog scale), flexion angle of the knee joint, analgesic consumption, and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire.ResultsNo significant differences were observed between the basil oil and diclofenac gel groups in any of the measured outcomes. …”
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A new kinetic model for biogas production from co-digestion by batch mode by D. Pham Van, M.G. Hoang, S.T. Pham Phu, T. Fujiwara

“…However, the model has failed to describe the starting point of the process, and no-sense of lag phase constant has been pointed out. …”
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An Overview of Pavement Degradation Prediction Models by Amir Shtayat, Sara Moridpour, Berthold Best, Shahriar Rumi

“…Moreover, many researchers have focused on pavement condition evaluation tools, starting with data collection, followed by processing, analyzing, and ultimately reaching practical conclusions regarding pavement condition. …”
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Preparation of Saccharomycopsis fibuligera Fuqu and Its Application in the Production of Xiaoqu Baijiu by LIU Xiao, HUANG Zhiguo, WEI Chunhui, REN Zhiqiang, XIE Jun, DENG Jie

“…In order to increase the content of ethyl acetate in Xiaoqu Baijiu, a strain of Saccharomycopsis fibuligera M1 with strong ester-producing capacity isolated from Daqu was used as the starting strain for preparing Fuqu (M1-Fuqu), which was subsequently used for the brewing of Xiaoqu Baijiu. …”
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A different story of modern economic science by Oreste Bazzichi, Fabio Reali

“… This paper wants to demonstrate a scenario where it is evident that the medieval society, starting from the monasticism of St. Benedict (famous motto of «ora et labora») and continuing with the Franciscan School, conserves many elements and ideas of intellectual interest that have a reverberation still valid for today, especially concerning the relationship of man with the economy. …”
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Theoretical frameworks for constructing a model for analysis of Islamic discourse on YouTube: one view from Serbia by Predrag Pavlićević

“…The starting point of this paper an assumption that videos on the YouTube Internet portal relating to Islam produce intolerant and radical discourse that may be a factor of radicalization through their contents, the ways of the shaping of the content, and by their presentation modes. …”
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Serum sodium to chloride ratio and mortality on continuous ambulatory peritoneal dialysis: a multicenter retrospective study by Jiayin You, Sijie Gu, Ning Su, Xiaoran Feng, Fenfen Peng, Qingdong Xu, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Na Tian, Xianfeng Wu, Niansong Wang

“…Initial levels of Na/Cl at the start of PD were negatively correlated with all‐cause mortality and cardiovascular mortality in PD patients.…”
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ANTIBIOTIC LOCK THERAPY FOR PORT CATHETER-RELATED INFECTIONS OF CHILDREN WITH ACUTE LEUKEMIA by Burçin Kurtipek, Ayça Koca Yozgat, Saliha Kanık Yüksek, Dilek Kaçar, Turan Bayhan, Dilek Gürlek Gökçebay, Aslınur Özkaya Parlak, Neşe Yaralı

“…Antibiotic lock therapy was started in 56 patients with bacterial growth in the port catheter. …”
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American Strategy of "Sufficient Presence" in the Middle East by I. V. Ryzhov, M. Yu. Borodina, T. V. Baranova

“…Trump came to power it started developing a new US Middle East policy, based on the regional threat assessment, such as the unstable political situation in a number of regional countries, radical regimes, terrorism, especially ISIS. …”
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Algorithm of Development for Stabilization of Socio-Ecological Situation in Karakalpakstan by Alisher Abdullaev

“…It is established that the Republic has several problems, the solution of which should be started shortly. Considerable attention is paid to the setting of tasks and using for this purpose methods of system analysis of socio-ecological factors. …”
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Protective and anti-inflammatory effects of caffeic acid phenethyl ester on arsenic-induced vasculitis in vivo by Yasser Kofiah, Eman A.A. Abdallah, Mohamed F. El-Refaei

“…Group III was intoxicated with AsIII at 10 mg/kg b.wt for 6 consecutive days, while Group IV was intoxicated with AsIII for 6 consecutive days and treated daily with 3 mg/kg b.wt of CAPE intraperitoneally starting from day 1 of intoxication up to 14 days. …”
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The pioneers of Vietnam’s epidemiological transition: an ethnographic study of pregnant women’s experiences of gestational diabetes by Tine M. Gammeltoft, Thi Ai Nguyen, Thi Kim Dung Vu, Ngoc-Anh Thi Dang, Thi Minh Phuong Nguyen, Van Tien Nguyen, Ib C. Bygbjerg

“…We conducted in-depth ethnographic interviews with 21 women with GDM, visiting them in their homes. Our theoretical starting point was phenomenological anthropology, and the data were analysed using a thematic analysis approach. …”
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Engagement in a web-based intervention for individuals who committed sexual offenses against children: observational study by Sonja Schröder, Safiye Tozdan, Peer Briken, Jürgen L. Müller, Peter Fromberger

“…However, the effectiveness of interventions is often limited by the fact that individuals do not start or complete them. Using data from an intermediate analysis of the randomized placebo-controlled clinical trial to evaluate the effectiveness of @myTabu, the current study investigated engagement with a web-based intervention for 113 individuals convicted of child sexual abuse and/or for child sexual exploitation material. …”
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Acceptability and Future Considerations for Telegenetic Counseling After the COVID Pandemic: Interviews with Genetic Counselors, Clinicians, and Patients by Meghan C. Martinez MPH, Nina Szwerinski MS, Su-Ying Liang PhD, Sharon Chan MPH, Monique de Bruin MD, Cheryl D. Stults PhD

“…While telegenetic counseling has increased substantially since the start of the COVID-19 pandemic, previous studies reported concerns around building rapport, nonverbal communication, and the patient-counselor relationship. …”
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Maze runners: monkeys show restricted Arabic numeral summation during computerized two-arm maze performance by Elizabeth L. Haseltine, Michael J. Beran

“…However, some biases occurred that were suboptimal: the largest single numeral and the delay of reward (by placing numerals farther into an arm from the start location) sometimes interfered with the monkeys’ abilities to optimize. …”
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A Case of Histoplasma capsulatum Causing Granulomatous Liver Disease and Addisonian Crisis by P Wong, S Houston, B Power, E Lalor, VG Bain

“…Screening serologies were positive for histoplasmosis, and he was started on itraconazole treatment. He returned to hospital the same night with coffee-ground emesis and in Addisonian crisis requiring parenteral steroids and intensive care unit support. …”
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