A Framework for the AI-based visualization and analysis of massive amounts of 4D tomography data for end users of beamlines by Steffen Kieß, Thomas Lang, Tomas Sauer, Andreas Michael Stock, Andrey Chernov, Yipeng Sun, Andreas K. Maier, Tomáš Faragó, Alexey Ershov, Gabriel Lefloch, Guilherme Silva, Tilo Baumbach, Simon Zabler, Astrid Hölzing, Kilian Dremel, Ali Riza Durmaz, Akhil Thomas, Ingo Manke, Nikolay Kardjilov, Tobias Arlt, Tak Ming Wong, Regine Willumeit-römer, Julian Moosmann, Berit Zeller-Plumhoff, Dieter Froning, Sven Simon

Get full text

Effects of Different Types of Cognitive Training on Cognitive Function, Brain Structure, and Driving Safety in Senior Daily Drivers: A Pilot Study by Takayuki Nozawa, Yasuyuki Taki, Akitake Kanno, Yoritaka Akimoto, Mizuki Ihara, Ryoichi Yokoyama, Yuka Kotozaki, Rui Nouchi, Atsushi Sekiguchi, Hikaru Takeuchi, Carlos Makoto Miyauchi, Takeshi Ogawa, Takakuni Goto, Takashi Sunda, Toshiyuki Shimizu, Eiji Tozuka, Satoru Hirose, Tatsuyoshi Nanbu, Ryuta Kawashima

“…For cognitive function, only Group V showed significant improvements in processing speed and working memory. For driving safety, Group V showed significant improvements both in the driving aptitude test and in the on-road evaluations. …”
Get full text

Implementing a closed loop clinical decision support system for sustainable preoperative care by José Luis Gracia Martínez, Bernadette Pfang, Miguel Ángel Morales Coca, Cristina Caramés Sánchez, Marta del Olmo Rodríguez, Marco Antonio Villegas García, Jorge Short Apellaniz, Javier Arcos Campillo, Juan Antonio Álvaro de la Parra, Florencia Manzano Lorefice, Luis Enrique Muñoz Alameda

“…Interrupted time series analysis was performed to evaluate changes in rates of preoperative testing after CDSS implementation, which took place from September 2019 to December 2019. …”
Get full text

Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

“…The machine learning analysis of the TIME had better accuracy than the human count evaluations (AUC of human count, CD8-positive lymphocyte: 0.681, FoxP3-positive lymphocytes: 0.626, PD-L1 score: 0.567).Conclusions The spatial analysis of the TIME using machine learning predicted the immunotherapy efficacy in patients with SCLC, thus supporting its role as an immunotherapy biomarker.…”
Get full text

Deep learning-based histopathological assessment of tubulo-interstitial injury in chronic kidney diseases by Nonoka Suzuki, Kaname Kojima, Silvia Malvica, Kenshi Yamasaki, Yoichiro Chikamatsu, Yuji Oe, Tasuku Nagasawa, Ekyu Kondo, Satoru Sanada, Setsuya Aiba, Hiroshi Sato, Mariko Miyazaki, Sadayoshi Ito, Mitsuhiro Sato, Tetsuhiro Tanaka, Kengo Kinoshita, Yoshihide Asano, Avi Z. Rosenberg, Koji Okamoto, Kosuke Shido

“…Notably, the DLRS-derived fibrosis score has a higher correlation with the estimated glomerular filtration rate (eGFR) at biopsy than scores from nephrologists’ evaluations. …”
Get full text

Surrounding Gastric Mucosa Findings Facilitate Diagnosis of Gastric Neoplasm as Gastric Adenoma or Early Gastric Cancer by Tadashi Miike, Shojiro Yamamoto, Yoshifumi Miyata, Tomoya Hirata, Yuko Noda, Takaho Noda, Sho Suzuki, Sachiko Takeda, Shuichiro Natsuda, Mai Sakaguchi, Kosuke Maemura, Kanna Hashimoto, Takumi Yamaji, Hiroo Abe, Hisayoshi Iwakiri, Yoshihiro Tahara, Satoru Hasuike, Kenji Nagata, Akira Kitanaka, Kazuya Shimoda

Get full text

RETRACTION Suyato, S., Setyawan, H., Sukarti, S. E. E., Shidiq, A. A. P., Darmawan, A., HB, G., Zulbahri, Z., Eken, Özgür, Pavlovic, R., Latino, F., & Tafuri, F. (2024).  La integración de los valores sociales en la educación física y el deporte para la formación del carácter de los alumnos adolescentes: una revisión sistemática (The integration of social values in physical education and sport to develop teenage students’ character: a systematic review). ... by RETOS RETOS

“…La integración de los valores sociales en la educación física y el deporte para la formación del carácter de los alumnos adolescentes: una revisión sistemática (The integration of social values in physical education and sport to develop teenage students’ character: a systematic review). …”
Get full text

Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E mutated colorectal cancer—results from the FIRE‐4.5 study by Susanne Klein‐Scory, Alexander Baraniskin, Wolff Schmiegel, Thomas Mika, Roland Schroers, Swantje Held, Kathrin Heinrich, David Tougeron, Dominik P. Modest, Ingo Schwaner, Jan Eucker, Rudolf Pihusch, Martina Stauch, Florian Kaiser, Christoph Kahl, Meinolf Karthaus, Christian Müller, Christof Burkart, Sebastian Stintzing, Volker Heinemann

“…The BRAF V600E variants in ctDNA were analyzable in 66 patients at start of the therapy, at baseline. No BRAF V600E mutations were detected in 26% (17/66) of patients and was associated with a significantly longer progression‐free survival (PFS: 13.2 vs 6.5 months; HR 0.47; P = 0.014) and overall survival (OS: 36.8 vs 13.2 months; HR 0.35; P = 0.02) as compared to ctDNA mutant patients. …”
Get full text

The COVID‐19 pandemic‐induced behavioral restrictions and their impact on child and adolescent psychiatric units—Infection control or freedom by Masahide Usami, Yoshinori Sasaki, Mayuna Ichikawa, Miki Matsudo, Mutsumi Ohashi, Yui Higashino, Yusuke Kono, Haruna Matsudo, Yuki Nomura, Minjae Ma, Yuuki Sakoh, Maiko Odaka, Kotoe Itagaki, Keita Yamamoto, Momoka Takahashi, Yuta Yoshimura, Saori Inoue, Masahiro Ishida, Kumi Inazaki, Yuki Hakoshima, Yuki Mizumoto

Get full text

Challenges of Engaging Primary Care Providers in Specialized Telementoring Education About Sickle Cell Disease for Sickle Cell Specialists: Results from the Sickle Cell Disease Tra... by Lisa M. Shook, DHPE, MA, MCHES, Bailey House, MPH, Christina Bennett Farrell, MPH, Rosalyn Stewart, MD, Sophie Lanzkron, MD, MHS, Allison A. King, MD, MPH, PhD, Taniya Varughese, MSOT, J.J. Strouse, MD, PhD, Marsha Treadwell, PhD, Julie Kanter, MD

Get full text

Neoadjuvant Chemoradiotherapy Upregulates the Immunogenicity of Cold to Hot Tumors in Esophageal Cancer Patients by Yushi Nagaki, MD, PhD, Satoru Motoyama, MD, PhD, Yusuke Sato, MD, PhD, Akiyuki Wakita, MD, PhD, Hiromu Fujita, MD, PhD, Kohei Kemuriyama, MD, Ryohei Sasamori, MD, Shu Nozaki, MD, Kyoko Nomura, MD, PhD, Yoshihiro Minamiya, MD, PhD

Get full text

Development of quality indicators for hand osteoarthritis care – Results from an European consensus study by Daniel H. Bordvik, Yeliz Prior, Rachael Bamford, Francis Berenbaum, Mathilda Björk, Thalita Blanck, Barbara Slatkowsky Christensen, Krysia Dziedzic, John Edwards, Nazemin Gilanliogullari, Carol Graham, Ida K. Haugen, Margreet Kloppenburg, Hellen Laheij, Marco J.P.F. Ritt, Tanja Stamm, Anne Therese Tveter, Nina Østerås, Ingvild Kjeken

“…Design: We used the OA-QI v.2. set as a starting point and adapted it to reflect hand OA care. …”
Get full text

Potential implications of thyroid autoantibodies in children, adolescents, and young adults with thyroid nodules in Japan: The Fukushima Health Management Survey by Rina Tazaki, Yurie Kobashi, Nana Nakahata, Mahiro Asano, Norikazu Abe, Haruka Ejiri, Ayako Sato, Natsuki Nagamine, Chisato Takahashi, Yukie Yamaya, Manabu Iwadate, Takashi Matsuzuka, Satoshi Suzuki, Tetsuya Ohira, Satoru Suzuki, Fumihiko Furuya, Hiroki Shimura, Shinichi Suzuki, Susumu Yokoya, Shunichi Yamashita, Hitoshi Ohto, Seiji Yasumura

“…After stratification of the data for body mass index (BMI) and the bilateral width and thickness of the area (BWTAR) as indicators of thyroid volume for age, sex, body surface area (BSA), and sex-adjusted standard deviation score (SDS), trend analyses were performed. A logistic regression analysis was performed using tab-positivity as an objective variable. …”
Get full text

Prevalence of thyroid diffuse goiter and its association with body mass index and the presence of cysts and nodules in children and adolescents: the Fukushima Health Management Sur... by Nana Nakahata, Mahiro Asano, Norikazu Abe, Haruka Ejiri, Hisashi Ota, Satoshi Suzuki, Ayako Sato, Rina Tazaki, Natsuki Nagamine, Chisato Takahashi, Yukie Yamaya, Manabu Iwadate, Takashi Matsuzuka, Tetsuya Ohira, Seiji Yasumura, Satoru Suzuki, Fumihiko Furuya, Hiroki Shimura, Shinichi Suzuki, Susumu Yokoya, Hitoshi Ohto, Kenji Kamiya

“…Logistic regression analyses were conducted to calculate the odds ratios of the standard deviation score of body mass index (BMI-SDS), the SDS of bilateral width multiplied thickness area (BWTAR-SDS) as a provisional determination of thyroid volume, and the presence of nodules or cysts for positive diffuse goiter compared with negative diffuse goiter after correction for sex and age. …”
Get full text

Energetic and genomic potential for hydrogenotrophic, formatotrophic, and acetoclastic methanogenesis in surface-expressed serpentinized fluids of the Samail Ophiolite by Alta E. G. Howells, Alta E. G. Howells, Lilja M. Quinn, Lilja M. Quinn, Miguel G. Silva, Miguel G. Silva, Kylie Akiyama, Kylie Akiyama, Lucas M. Fifer, Lucas M. Fifer, Grayson Boyer, Srishti Kashyap, Kirt Robinson, Kirt Robinson, Jared Broddrick, Everett L. Shock, Tori M. Hoehler

“…Serpentinization, the reaction of water with ultramafic rock, produces reduced, hyperalkaline, and H2-rich fluids that support a variety of hydrogenotrophic microbial metabolisms. Previous work indicates the occurrence of methanogenesis in fluids from the actively serpentinizing Samail Ophiolite in the Sultanate of Oman. …”
Get full text

Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma by Anahita Fathi Kazerooni, Adam Kraya, Komal S. Rathi, Meen Chul Kim, Arastoo Vossough, Nastaran Khalili, Ariana M. Familiar, Deep Gandhi, Neda Khalili, Varun Kesherwani, Debanjan Haldar, Hannah Anderson, Run Jin, Aria Mahtabfar, Sina Bagheri, Yiran Guo, Qi Li, Xiaoyan Huang, Yuankun Zhu, Alex Sickler, Matthew R. Lueder, Saksham Phul, Mateusz Koptyra, Phillip B. Storm, Jeffrey B. Ware, Yuanquan Song, Christos Davatzikos, Jessica B. Foster, Sabine Mueller, Michael J. Fisher, Adam C. Resnick, Ali Nabavizadeh

Get full text