Single-cell and spatial atlas of glioblastoma heterogeneity: characterizing the PCLAF+ subtype and YEATS4’s oncogenic role by Siqi Ma, Yuwei Sun, Shaowei Zheng, Yilong Fu, Liangyu Wang, Dun Liu, Henan Jiao, Xuqiang Zhu, Xueyuan Li, Dongming Yan, Di Chen, Zi Ye

“…Therefore, multi-dimensional therapeutic strategies targeting GBM-specific molecular features, its intrinsic properties, and microenvironmental regulatory networks were considered to potentially provide new breakthroughs for overcoming treatment resistance in GBM.MethodsWe analyzed single-cell RNA sequencing (scRNA-seq) data processed with the Seurat package to accurately identify cell types. Spatial transcriptomics integrated Multimodal Intersection Analysis, TransferData, and Robust Cell Type Decomposition techniques to characterize the spatial distribution patterns of key cell subtypes. …”
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Spatial and Seasonal Variation and the Driving Mechanism of the Thermal Effects of Urban Park Green Spaces in Zhengzhou, China by Yuan Feng, Kaihua Zhang, Ang Li, Yangyang Zhang, Kun Wang, Nan Guo, Ho Yi Wan, Xiaoyang Tan, Nalin Dong, Xin Xu, Ruizhen He, Bing Wang, Long Fan, Shidong Ge, Peihao Song

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A feature fusion network with spatial-temporal-enhanced strategy for the motor imagery of force intensity variation by Ankai Ying, Ankai Ying, Ankai Ying, Jinwang Lv, Jinwang Lv, Jinwang Lv, Junchen Huang, Junchen Huang, Junchen Huang, Tian Wang, Peixin Si, Peixin Si, Jiyu Zhang, Guokun Zuo, Guokun Zuo, Guokun Zuo, Guokun Zuo, Jialin Xu, Jialin Xu, Jialin Xu, Jialin Xu

“…This model combines a multi-scale spatial-temporal convolution module with a spatial-temporal-enhanced strategy, a convolutional auto-encoder for information reconstruction, and a long short-term memory with self-attention, enabling the comprehensive extraction and fusion of EEG features across fine-grained time-frequency variations and dynamic spatial-temporal patterns.ResultsThe proposed FN-SSIR achieved a classification accuracy of 86.7% ± 6.6% on our force variation MI dataset, and 78.4% ± 13.0% on the BCI Competition IV 2a dataset.DiscussionThese findings highlight the potential of this paradigm and algorithm for advancing MI-BCI systems in rehabilitation training based on dynamic force interactions.…”
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High-resolution 3D spatial distribution of complex microbial colonies revealed by mass spectrometry imaging by Yuting Shen, Yisu Wang, Jianing Wang, Peisi Xie, Chengyi Xie, Yanyan Chen, Niaz Banaei, Kangning Ren, Zongwei Cai

“…Additionally, we investigated metabolite spatiotemporal dynamics in multiple colonies, observing changes over time and distinct patterns in single versus merged colonies. These findings shed light on the repel-merge process for multi-colony formation. …”
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White matter hyperintensity tissue property spatial variations as a function of cognitive status in Parkinson’s disease by Mariyemuguli Reheman, Sagar Buch, Naying He, Pei Huang, Qiurong Yu, Xinhui Wang, Yu Liu, Youmin Zhang, Zhijia Jin, Yan Li, Peng Liu, Shengdi Chen, E. Mark Haacke, Fuhua Yan

“…Conclusion: Over and above volume differences, the spatial distribution and tissue property variations of WMH were closely linked to cognitive impairment in PD patients, with distinct patterns across different cognitive stages.…”
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Evaluation proceeds model middling kriging in distribution spatial land use city (Case study: city Kerman) by Ali Asghsr Abdollahi, moslem ghasemi

“…Analysis probative spatial data method for checking patterns spatial accidental and accidental is distribution variables spatial and correlation spatial from more usage and more important tools Analysis for is the research in the case spatial data. …”
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Water quality and spatial dynamics: A GIS-enhanced multi-scale study of Guangdong's port and shipping service industry by Yubao Wang, Rong Chen, Jing Su, Anyang Weng, Yibo Jiang

“…Using ArcGIS 10.8, spatial metrics are calculated at scales from 2 to 30 km to identify clustering and distribution patterns. …”
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Propagation of optical spatial solitons in nematic liquid crystals with quadruple power law of nonlinearity appears in fluid mechanics by Yousaf Muhammad Zain, Abbas Muhammad, Lupas Alina Alb, Abdullah Farah Aini, Iqbal Muhammad Kashif, Alharthi Muteb R., Hamed Yasser S.

“…Novel solutions, such as the periodic pattern, kink and anti-kink patterns, N-pattern, W-pattern, anti-Z-pattern, M-pattern, V-pattern, complexion pattern and anti-bell pattern, or dark soliton solutions of nematic LCs, have been constructed by means of modified extended Fan subequation technique through granting suitable values for the parameters. …”
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Ecological resilience of three major urban agglomerations in China from the “environment–society” coupling perspective by Huiping Wang, Qi Ge

“…Three major urban agglomerations in China are considered to construct a framework for measuring ecological resilience from the perspective of the “environment–society” coupling; the spatial and temporal characteristics of ecological resilience are clarified, and the spatial associations of ecological resilience within urban agglomerations are deconstructed. …”
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A Marginal Maximum Likelihood Approach for Hierarchical Simultaneous Autoregressive Models with Missing Data by Anjana Wijayawardhana, David Gunawan, Thomas Suesse

“…This complexity applies when the spatial weight matrix is constructed based on a local neighbourhood structure. …”
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Reading Tabriz Municipality Building Based on Foucault’s Theory of Power by Noushin Ghorbani, Sahar Toufan, Habib Shah Hosseini, Nima Vali Zadeh, Hassan Sattari Sarbangholi

“…The features mentioned above could play a significant role in visual and physical control of the interiors of a building, as well as creating a spatial discipline. The results pointed to a pattern that can be used in the design of public buildings by city managers.…”
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Location factors and agglomeration economies in the hotel industry: the case of Spain by Andrea Valenzuela-Ortiz, Jorge Chica-Olmo, José-Alberto Castañeda

“…Social implications – The results of this study can help city planners in influencing the distribution of hotels to fit desired patterns and improve an area's spatial beauty. Originality/value – The paper provides insights into how investment, structural characteristics, reputation and location affect hotel revenue.…”
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Spatial and temporal variation in the occurrence of bottlenose dolphins in the Chesapeake Bay, USA, using citizen science sighting data. by Lauren Kelly Rodriguez, Amber D Fandel, Benjamin R Colbert, Jamie C Testa, Helen Bailey

“…Although widely studied, little is known about their occurrence patterns in the highly urbanized estuary of the Chesapeake Bay, USA. …”
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Spatial coupling mechanisms of food security and regional economies: empirical examination of core-periphery dynamics in Jiangsu Province (2001–2024) by Yongqing Ben, Yongqing Ben, Yu'e Zhang, Jinhai Xu

“…This study investigates the spatiotemporal dynamics of grain production and its spatial interaction with economic development in Jiangsu Province, China—an economically advanced region exemplifying this tension.MethodsWe integrate the Gini coefficient, concentration index, standard deviational ellipse, spatial exploratory analysis (global/local Moran's I), and a Spatial Durbin Model (SDM) to quantify spatial differentiation patterns and spillover effects.Results(1) Pronounced spatial polarization emerged: Northern Jiangsu consolidated as a High-High grain production cluster, while Southern Jiangsu evolved into a Low-Low cluster. …”
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Monitoring the dynamics of coastal wetlands ecosystems in Brittany (France) using LANDSAT time series and machine learning by Adrien Le Guillou, Simona Niculescu

“…The results revealed contrasting spatial patterns. The Audierne Bay has experienced significant urban expansion, with a 24% increase upstream, as well as coastal erosion reaching 1.63 m/year locally, with a retreat of approximately 50 m in the most affected areas during the period 1990–2020. …”
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Quantifying the Spatiotemporal Variations of Soil Nitrogen Fixation or Absorption from Soybean, Cotton, and Maize Planted Fields to Support Sustainable Agriculture Practices by José Bofana, Raul Domingos Mussane, Rosalina Armando Tamele, Ana Cristina Costa, Barreta Savanguane, Ivans Popinsky, António F. Matusse

“…The Inverse Distance Weighted (IDW) method was used for mapping the spatial total soil nitrogen distribution. The results revealed distinct total soil nitrogen credit and debit patterns. …”
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Formulating sustainable planning for Goulan Yao Village based on the integration of cultural landscape gene theory and spatial analysis by Mengen Gu, Yajing Wang, Yang Wu, Yue Dai, Wei Fan

“…This study centers on Goulan Yao Village in Jiangyong County, China, applying cultural landscape gene theory combined with GIS spatial analysis. A gene information chain map and a village-specific classification and coding system were established to analyze spatial distribution and organizational patterns. …”
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Two-Step Phase-Shifting Algorithm Based on the Quadratic Spatial Filtering of Interferograms by Xianxin Han, Linna Xie, Yi Wang, Jiaosheng Li, Liyun Zhong, Xiaoxu Lu

“…Second, there is no requirement about the fringe density of interference pattern, reflecting the phase shift estimation can be realized even if the fringes density is sparse. …”
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The temporal and spatial evolution law of seepage parameters in the filter based on the CFD-DEM coupled flow-solid approach by Song Jingyu, Dang Faning, Gao Jun, Zhu Wuwei, Yao Yi

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An exploration of the research framework for the coupling of farmland and rural residential land use transition under the perspective of spatial production by LI Jingjing, FENG Yingbin, GU Lei, LI Yue

“…Overall, the research framework of “feature identification - pattern judgment - mechanism response” for the coupling of farmland and rural residential land use transition from the perspective of spatial production was formed. …”
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