Satellite Altimetry-based Extension of global-scale in situ river discharge Measurements (SAEM) by P. Saemian, O. Elmi, M. Stroud, R. Riggs, B. M. Kitambo, F. Papa, G. H. Allen, M. J. Tourian

“…These water level time series are sourced from both existing Level-3 water level time series and newly generated ones within this study. …”
Get full text

Assessing the impact of diet formulation and age on targeted bacterial establishment in laboratory and mass-reared Mediterranean fruit fly using full-length 16S rRNA sequencing by Charles J. Mason, Rosalie C. Nelson, Mikinley Weaver, Tyler J. Simmonds, Scott M. Geib, Ikkei Shikano

“…In laboratory and mass-reared insects, gut microbiomes can differ in composition and function compared to wild conspecifics. For fruit flies, such as the Mediterranean fruit fly (medfly; Ceratitis capitata), these changes can influence male performance and behavior. …”
Get full text

Spatiotemporal Evolution Characteristics and Trade-offs/Synergies of Water Yield, Soil Conservation, and Carbon Storage Ecosystem Services in the Beiluo River Basin from 1970 to 20... by ZHANG Yujie, ZHANG Xiaoping, SUN Weinan, GENG Wenliang, AN Zefeng, CHEN Qingwei

“…［Objective］ This study aimed to investigate the spatiotemporal changes and trade-offs/synergies of ecosystem services within the Beiluo River basin to provide a scientific foundation for rational resource allocation and sustainable development. ［Methods］ Utilizing multi-source data and models, such as InVEST and CSLE, to quantitatively assess and analyze the spatiotemporal variations and trade-offs/synergies of three key ecosystem services-water yield, soil conservation, and carbon storage-across different periods. …”
Get full text

A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain by Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

“…Morgan P Lorio,1 Douglas P Beall,2 Thomas J Myers,3 Ramana K Naidu,4 W Porter McRoberts,5 Timothy T Davis,6 Emmanuel G Gage,7 Aaron K Calodney,8 Paul Verrills,9 Michael J De Palma,10 Kasra Amirdelfan,11 Jon E Block12 1Orlando College of Osteopathic Medicine, Winter Garden, FL, USA; 2Comprehensive Specialty Care, Edmond, OK, USA; 3Paradigm Health System, Slidell, LA, USA; 4MarinHealth Spine Institute, Larkspur, CA, USA; 5Holy Cross Medical Group, Fort Lauderdale, FL, USA; 6Source Healthcare, Santa Monica, CA, USA; 7Centurion Spine & Pain Centers, Waycross, GA, USA; 8Precision Spine Care, Tyler, TX, USA; 9MetroPain Group, Clayton, VIC, Australia; 10Virginia iSpine Physicians, Richmond, VA, USA; 11Boomerang Healthcare, Inc., Walnut Creek, CA, USA; 12Private Practice, San Francisco, CA, USACorrespondence: Jon E Block, Private Practice, 2210 Jackson Street, Ste. 401, San Francisco, CA, 94115, USA, Tel +1 415-775-7947, Email jb@drjonblock.comBackground: There is renewed interest in the intervertebral disc as a target for treatments aimed at ameliorating lumbar discogenic pain by restoring and preserving the natural structure and function of this component of the vertebral motion segment.Methods: Using a modified Delphi methodology involving a panel of 11 experts, we developed a simple, understandable clinical algorithm to serve as a foundation for objective decision making regarding the diagnosis and treatment of lumbar discogenic pain throughout the entire continuum of care. …”
Get full text

TGFβ1 Restores Energy Homeostasis of Human Trophoblast Cells Under Hyperglycemia In Vitro by Inducing PPARγ Expression, AMPK Activation, and HIF1α Degradation by Nihad Khiat, Julie Girouard, Emmanuelle Stella Kana Tsapi, Cathy Vaillancourt, Céline Van Themsche, Carlos Reyes-Moreno

“…Trophoblast cells predominantly utilize glucose as an energy source, metabolizing it through glycolysis in the cytoplasm and oxidative respiration in the mitochondria to produce ATP. …”
Get full text

Research on Pedestrians’ Visual Perception Characteristics Based on USGGS: A Case Study of the Six Inner-City Districts of Tianjin by Hanwen YANG, Shang’en TSOU, Yike HU

“…The core objective of the research is to propose strategies to optimize the greening structure of urban streets by analyzing the correlation between USGGS and visual perception of pedestrians, so as to enhance the quality of the visual environment of street pedestrians, improve the urban human settlement environment and promote the organic integration of the urban ecological and humanistic environments, thus providing a new way of thinking for urban planning and construction, and promoting the high-quality and sustainable development of urban street space.MethodsThe research selects the six inner-city districts of Tianjin City as the research area, utilizes Baidu street view image (SVI) as data source, and collect SVIs and their coordinates in the six districts in 2019 by calling Baidu API, with a total of 17,326 points selected and 13,281 valid samples obtained after screening. …”
Get full text

Submillimeter and Mid-infrared Variability of Young Stellar Objects in the M17 H II Region by Zhiwei Chen, Doug Johnstone, Carlos Contreras Peña, Jeong-Eun Lee, Sheng-Yuan Liu, Gregory Herczeg, Steve Mairs, Geumsook Park, Kee-Tae Kim, Mi-Ryang Kim, Keping Qiu, Yao-Te Wang, Xu Zhang, Megan Reiter, The JCMT Transient Team

“…This mid-IR fractional variability as a function of evolutionary stage result is similar to what has previously been found for YSO variability within the Gould Belt and the intermediate-mass star formation region M17 SWex, though overall less variability is detected in M17 in submillimeter and mid-IR. …”
Get full text

Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…Transition probabilities pertaining to low-dose ICS were adjusted by relative risks for asthma control and exacerbations for alternative treatments, derived from a NMA. Health state utilities were identified from literature sources. …”
Get full text

Pancreatic β-cells package double C2-like domain beta protein into extracellular vesicles via tandem C2 domains by Diana Esparza, Carinna Lima, Sarah Abuelreich, Ima Ghaeli, Jinhee Hwang, Eunjin Oh, Ayelet Lenz, Angel Gu, Nan Jiang, Fouad Kandeel, Debbie C. Thurmond, Tijana Jovanovic-Talisman

“…Moreover, in rat clonal β-cells, we probed domains required for DOC2B sorting into EVs.MethodUsing Single Extracellular VEsicle Nanoscopy, we quantified EVs derived from clonal β-cells (human EndoC-βH1, rat INS-1 832/13, and mouse MIN6); two other cell types known to regulate glucose homeostasis and functionally utilize DOC2B (skeletal muscle rat myotube L6-GLUT4myc and human neuronal-like SH-SY5Y cells); and human islets sourced from individuals with no diabetes (ND). …”
Get full text

Research Progress on the Impact of Nighttime Outdoor Environments on Residents’ Health by Chongxian CHEN, Xinrui XIONG, Guangsi LIN, Jingyi LIU

“…Additionally, nighttime recreational activities function as a vital medium for interaction between individuals and their environment, with the realization of health benefits depending on the combined influence of multiple environmental factors. …”
Get full text

Integrated single-cell analysis reveals the regulatory network of disulfidptosis-related lncRNAs in bladder cancer: constructing a prognostic model and predicting treatment respons... by Jiafu Xiao, Jiafu Xiao, Jiafu Xiao, Wuhao Liu, Wuhao Liu, Wuhao Liu, Jianxin Gong, Jianxin Gong, Jianxin Gong, Weifeng Lai, Weifeng Lai, Weifeng Lai, Neng Luo, Neng Luo, Neng Luo, Yingfan He, Junrong Zou, Junrong Zou, Zhihua He, Zhihua He, Zhihua He

“…This study aims to investigate disulfidptosis-related lncRNAs (DRLs) as potential prognostic markers for BLCA patients.MethodsUtilizing single-cell sequencing data, RNA sequencing data, and corresponding clinical information sourced from the GEO and TCGA databases, this study conducted cell annotation and intercellular communication analyses to identify differentially expressed disulfide death-related genes (DRGs). …”
Get full text

Examining the cultuling of Iranians’ concerns for others: From apathy to metapathy by Reza Pishghadam, Shima Ebrahimi

“…These utterances were collected from written texts across various sources. Subsequently, the expressions related to concern were carefully analyzed utilizing the conceptual model of cultuling analysis (CLA). …”
Get full text

Architecture and the Time of Space by Deborah Hauptman

“…As Foucault suggested, one of the great problems that arose in the 1950s was that of the political status of science and the ideological functions that it could serve. Another rebuke can be seen as the challenge to the primacy of truth as an adequation of subject to thing. …”
Get full text

Presenting a Quantum Leadership Model to Establish Organizational Civilization in the Iranian Higher Education System by reza heydari, hamidreza rezaeekelidbari, musa chaman zamin

“…The results of this study showed that by implementing the model obtained in this study, we can witness positive consequences in terms of implementing quantum leadership in order to establish organizational civilization in the country's higher education Extended abstract Introduction Creating new knowledge has long been one of the main functions of universities, and the greatest effort of the academic community is to promote knowledge and strengthen intellectual capital by utilizing existing informational, intellectual, and human resources; therefore, universities must identify, extract, and utilize these resources using new and appropriate leadership and management methods. …”
Get full text

µID-TIMS: spatially resolved high-precision U–Pb zircon geochronology by S. Markovic, J.-F. Wotzlaw, D. Szymanowski, J. Reuteler, P. Zeng, C. Chelle-Michou

“…The accuracy and precision of <span class="inline-formula">µ</span>ID-TIMS dates for zircon of any given age depend, as for non-microsampled zircon, on the available mass of U and radiogenic Pb – both a function of sample size. Our accompanying open-source code can aid researchers in estimating the necessary microsample size needed to obtain accurate dates at precision sufficient to resolve the processes under study. …”
Get full text

Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
Get full text

iMeta Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health by Yao Wang, Huiyu Hou, Hao Luo, Jiani Xun, Chuang Ma, Haifei Yang, Defeng Bai, Salsabeel Yousuf, Hujie Lyu, Tianyuan Zhang, Xiulin Wan, Xiaofang Yao, Tengfei Ma, Yuanping Zhou, Zhihao Zhu, Meiyin Zeng, Sanqi An, Qing Bai, Yao Bai, Guodong Cao, Tingting Cao, Yongkai Cao, Chihmin Chang, Lijia Chang, Bo Chen, Dai Chen, Dijun Chen, Hanqing Chen, Jiali Chen, Jinfeng Chen, Wei‐Hua Chen, Xinhai Chen, Yue Chen, Zhangran Chen, Cheng Cheng, Quan Cheng, Xi‐Jian Dai, Chaowen Deng, Feilong Deng, Jingwen Deng, Chang‐Sheng Dong, Lei Dong, Lianhui Duan, Yi Duan, Qingjie Fan, Chao Fang, Tingyu Fang, Wensheng Fang, Zhencheng Fang, Min Fu, Minjie Fu, Cong Gao, Hao Gao, Weiwei Gao, Xinrui Gao, Yi‐Zhou Gao, Yan Geng, Wenping Gong, Shaohua Gu, Xia Gu, Zhengquan Gu, Jian‐Wei Guo, Junjie Guo, Qiuyan Guo, Xiang Guo, Xiaoqian Guo, Dongfei Han, Ziyi Han, Yanan Hao, Jiale He, Jianquan He, Jianyu He, Ruolin He, Guosen Hou, Bin Hu, Haibo Hu, Yi Hu, Yongfei Hu, Yucan Hu, Guanyin Huang, Haiyun Huang, Jiaomei Huang, Shenghui Huang, Baolei Jia, Xingxing Jian, Chao Jiang, Kun Jiang, Lanyan Jiang, Shuaiming Jiang, Jian‐Yu Jiao, Hao Jin, Jiajia Jin, Siyuan Kong, Xinxing Lai, Yuxin Leng, Bang Li, Bing Li, Fang Li, Hao Li, Huanjie Li, Jing Li, Kai Li, Lanqi Li, Leyuan Li, Minghan Li, Pengsong Li, Wei Li, Wei Li, Xianyu Li, Li Xuemeng, Yafei Li, Yuantao Li, Zhi Li, Liqin Liang, Rong Liang, Zhuobin Liang, Qingya Liu, Dejian Liu, Huiheng Liu, Jinchao Liu, Li Liu, Lihui Liu, Moyang Liu, Ran Liu, Shuai Liu, Tianyang Liu, Wei Liu, Wenjuan Liu, Xiaomin Liu, Yang Liu, Yichen Liu, Yina Liu, Yuan Liu, Zhe Liu, Zhipeng Liu, Zhiquan Liu, Chunhao Long, Yun Long, Changying Lu, Chao Lu, Cheng Lu, Qi Lu, Yaning Luan, Peng Luo, Sheng Luo, Ning Ma, Xiao‐Ya Ma, Yan Ma, Wenjun Mao, Yuanfa Meng, Yan Ni, Yawen Ni, Kang Ning, Dongze Niu, Kai Peng, Zhengwu Peng, Xubo Qian, Zhiguang Qiu, Hui Qu, Zepeng Qu, Yan Ren, Zhigang Ren, Youming Shen, Lin Shi, Linlin Shi, Wenxuan Shi, Yongpeng Shi, Tianyuan Song, Xiaohui Song, Xiaoming Song, Xiaowei Song, Qi Su, Yufan Su, Lifang Sun, Qiang Sun, Tiefeng Sun, Yunke Sun, Hua Tang, Wenjing Tang, Tao Yu, Simon Tian, Shuo Wang, Bowen Wang, Cheng Wang, Wang Jin, Leli Wang, Liangliang Wang, Lixiao Wang, Mingbang Wang, Ming‐Ke Wang, Pingyi Wang, Shaolin Wang, Shaopu Wang, Xinxia Wang, Xueqiang Wang, Mi Wei, Yan Wei, Yanxia Wei, Yongjun Wei, Chaoliang Wen, Xin Wen, Linkun Wu, Shengru Wu, Yuting Wu, Shuting Xia, Xiaodong Xia, Yu Xia, Xionggen Xiang, Chuanxing Xiao, Weihua Xiao, Yingping Xiao, Ruohan Xie, Rui Xing, Hui Xu, Wei Xu, Zhimin Xu, Hongliang Xue, Chao Yan, Qiu‐Long Yan, Shaofei Yan, Xiuchuan Yan, Mengli Yang, Yufan Yang, Zhipeng Yang, Ziyuan Yang, Guixiang Yao, Yanlai Yao, Xianfu Yi, Chong Yin, Mingliang Yin, Shicheng Yu, Ying Yu, Yongyao Yu, Fusong Yuan, Shao‐Lun Zhai, Bo Zhang, Chen Zhang, Fang Zhang, Feng‐Li Zhang, Hengguo Zhang, Jinping Zhang, Junya Zhang, Kun Zhang, Li Zhang, Lin Zhang, Lingxuan Zhang, Meng Zhang, Qian Zhang, Runan Zhang, Tongtong Zhang, Tongxue Zhang, Weipeng Zhang, Yong Zhang, Yuchao Zhang, Yujun Zhang, Zeng Zhang, Zhengxiao Zhang, Zhi‐Feng Zhang, Boxi Zhao, Yanyan Zhao, Yibing Zhao, Ziwei Zhao, Diwei Zheng, Ying Zheng, Wenqiang Zhi, Jixin Zhong, Xiangjian Zhong, Wei Zhou, Xin Zhou, Zhemin Zhou, Zhichao Zhou, Congmin Zhu, Feiying Zhu, Xiaodie Zhu, Yutian Zou, Hongling Zhou, Lei Lei, Yanliang Bi, Hubing Shi, Hui‐Zeng Sun, Shuangxia Jin, Wenkai Ren, Lei Dai, Xin Wang, Canhui Lan, Hongwei Liu, Shuang‐Jiang Liu, Yulong Yin, Chun‐Lin Shi, Ren‐You Gan, Fangqing Zhao, Jun Yu, Tong Chen, Xin Hong, Hua Yang, Bangzhou Zhang, Shifu Chen, Xiaodong Li, Yunyun Gao, Yong‐Xin Liu

Get full text

An Examination and Critique of Bottom-Up Causation in the Interpretation of Free Will, Focusing on the Non-Reductionist Approach by Tayybhe Gholami, Zahra khazaei

“…The problem with this type of physicalism is that it negates the potentials and functions attributed to the soul. In contrast, non-reductionist physicalism does not adhere to such a notion; instead, it seeks to prove that all potentials are dependent on the body in relation to the world, culture, environment, and God.Non-reductionists believe that a serious challenge faced by reductionists is how to understand free will and moral responsibility. …”
Get full text

Comparing the Effectiveness of Self-Compassion and Mindfulness Therapies on Affection Control of Poor Parenting Adolescents by Zahra EffatDoost Sani, Mohammad Reza Zarbakhsh Bahri, Alireza Homayuni

“…Epsilon modification was applied, and Greenhouse Geisser statistics was utilized to test the examinees’ inner effects.Table 2 The Results repeated measure analysis of variance on Experimental and Control Groups in Pre, Post and follow up with Greenhouse - Geisser Scale  Source of ChangesSum of SquaresdfMean SquaresFpEta SquareStatistical PowerAffection ControlInner GroupsIntervention Levels4233.411.5327602.9964.540.0010.531Intervention Levels × Group1407.223.064599.3310.570.0010.170.99Within groupsGroup17394.0887.21427.679.280.0010.240.97The results indicated that the self-compassion and mindfulness treatments were effective with 0.24 effect (p= 0.001) on affection control of adolescences, which were significantly different from the control group. …”
Get full text

Urodynamics tests for the diagnosis and management of male bladder outlet obstruction: long-term follow-up of the UPSTREAM non-inferiority RCT by Madeleine Clout, Amanda L Lewis, Madeleine Cochrane, Grace J Young, Paul Abrams, Peter S Blair, Christopher Chapple, Gordon T Taylor, Sian Noble, Tom Steuart-Feilding, Jodi Taylor, J Athene Lane, Marcus J Drake

“…There was also no difference in other lower urinary tract symptoms, sexual function or quality of life. Routine data were received for 98% of men. …”
Get full text