Cytotoxicity of L-asparaginase from eucaryotic Cladosporium species against breast and colon cancer in vitro by Dina Johar, Hamido M. Hefny, Moselhy S. Mansy, Amal A. I. Mekawey, Mohammed S. Abdulrahman, Samy Zaky

“…Submerged fermentation was employed to optimize enzyme production. The enzyme activity was quantified using the Nesslerization method, and its cytotoxicity against colon and breast cancer cell lines was assessed using the (MTT) assay. …”
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Effect of Periodic Fluctuations of Cutting Mode Parameters on the Temperature of the Front Face of a Turning Tool by E. V. Fominov, V. E. Gvindjiliya, A. A. Marchenko, C. G. Shuchev

“…However, few works consider uncontrolled periodic disturbances, whose sources are spindle units and the supporting system of the machine. …”
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Targeted proteomics for absolute quantification of glucose transporter 1 in mammalian brain cells using liquid chromatography-mass spectrometry by Yash Mehta, Dhavalkumar Patel, Iqra Pervaiz, Ulrich Bickel, Abraham Jacob Al-Ahmad

“…Taken together, we have developed and optimized a proteomic method for the absolute quantification of GLUT1 in mammalian cells, which allows an alternative method for protein quantification independent of the antibody-based ones.…”
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The Attitudes Toward Polypharmacy and Willingness to Deprescribe Among Patients with Multimorbidity in Rural Areas of Shandong Province in China: A Cross-Sectional Study by Liu X, Zhao Y, Da T, Zhang S, Wang H, Li H

“…This necessitates medication optimization through deprescribing. Understanding patients’ decision-making preferences regarding medication cessation is crucial for mitigating medication-related risks. …”
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Analysis of Temperature Characteristics of Electrolytic-Plasma Discharge in Jet Processing of a Metal Anode by A. I. Popov, V. I. Novikov, D. N. Ivanov, I. A. Kozyrskiy

“…The lack of comprehensive studies of the temperature characteristics of jet EPD limits the optimization of processes. The research objective is to determine the distribution of temperatures and heat flows in the system “jet electrolytic cathode — metal anode” under various processing conditions.Materials and Methods. …”
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Medical and Social Peculiarities of the Health Condition of Pupils of Lviv and Lviv Region by Nyankovskyy S., Iatsula M., Senkevich O., Pasichnuk I., Kulik I.

“…The results of numerous studies show that the source of the differences in adult health should be sought in their childhood. …”
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Designing a Model for Implementing Digital Banking Policy Based on Using Big Data in Iranian Banking Industry by Rahmatollah Gholipour Souteh, Hamed Esmaeili Rad

“…The research emphasizes the pivotal role of big data technology, which has received limited attention but has a significant impact on achieving the goals and ensuring the optimal implementation of digital banking. Methods This research falls within the realm of qualitative and postmodern studies, adopting an inductive approach. …”
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Accelerating EdDSA Signature Verification with Faster Scalar Size Halving by Muhammad ElSheikh, İrem Keskinkurt Paksoy, Murat Cenk, M. Anwar Hasan

“…For the first time ever, EEA generated half-size scalars are used for verification of individual Ed25519 signatures yielding timing results that outperform ed25519-donna, a highly optimized open source implementation, by 16.12%. We also propose a new randomization method applied with half-size scalars to batch verification of Ed25519 signatures for which we report speed-ups compared to the well-known Bernstein et al. method for batch sizes larger than six, specifically, our method achieves 11.60% improvement for batch size 64. …”
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Toxic risk assessment of selected metals in infant formula milk commercially available in Lebanon: A novel approach based on feeding parameters versus toxicity by Pierre J. Obeid, Bilal El Khoury, John Hanna El-Nakat

“…Infant formula milk (IFM) is increasingly utilized as a substitute for natural breastfeeding despite the fact that breast milk has been always recognized as the optimal nourishment method. While IFMs are fortified with essential nutrients that are crucial for proper growth, they can also harbor non-essential toxic metal contaminants from various sources during the production process. …”
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Research on Urban Rainfall Runoff Pollution Prediction Model Based on Feature Fusion by Junping Yao, Tianle Sun

“…The pollution concentration of runoff was obtained by the exponential function method. The experimental results show that the predicted values of discharge and pollution concentration are well fitted with the actual values, indicating that the proposed method has high accuracy and feasibility. …”
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Isolation and Comprehensive Analysis of Cochlear Tissue‐Derived Small Extracellular Vesicles by Pei Jiang, Xiangyu Ma, Xinlin Wang, Jingyuan Huang, Yintao Wang, Jingru Ai, Hairong Xiao, Mingchen Dai, Yanqin Lin, Buwei Shao, Xujun Tang, Wei Tong, Zixuan Ye, Renjie Chai, Shasha Zhang

“…Currently, studies on the role of sEVs in the cochlea have relied on studying sEVs from in vitro sources. This study evaluates three cochlear tissue digestion and cochlear tissue‐derived sEV (CDsEV) isolation methods, and first proposes that the optimal approach for isolating CDsEVs using collagenase D and DNase І combined with sucrose density gradient centrifugation. …”
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Cystic Artery Bleeding: Imaging Insights and Systematic Review of Endovascular Management by Francesco Tiralongo, Davide Giuseppe Castiglione, Rosita Comune, Stefano Palmucci, Chandra Bortolotto, Fiore De Simone, Filomena Pezzullo, Giovanni Ferrandino, Giacomo Sica, Paolo Ricci, Mariano Scaglione, Antonio Basile, Stefania Tamburrini

“…Conclusions: The findings reinforce the importance of early diagnosis and tailored intervention strategies to optimize outcomes in CAB management.…”
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Direct Disk Diffusion Testing and Antimicrobial Stewardship for Gram-Negative Bacteremia in the Context of High Multidrug Resistance by Wantin Sribenjalux, Pawarit Kulwongroj, Waewta Kuwatjanakul, Lumyai Wonglakorn, Kanuengnit Srisak, Natapong Manomaiwong, Atibordee Meesing

“…In contrast, receiving optimal therapy within 72 h was associated with reduced mortality. …”
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Constrained total least squares localization using angle of arrival and time difference of arrival measurements in the presence of synchronization clock bias and sensor position er... by Ruirui Liu, Ding Wang, Jiexin Yin, Ying Wu

“…Subsequently, a set of pseudo-linear equations are constructed, based on which the constrained total least squares optimization model has been formulated for target localization and the Newton iteration is applied to obtain the source position and clock bias simultaneously. …”
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Peasantry and State Policy in the Field of Alcohol Sales in Russia at the Beginning of the 20th Century by I. A. Shevchenko

“…The article is devoted to the problem of finding optimal mechanisms for the struggle for national sobriety in Russia at the beginning of the 20th century. …”
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ANN-Based Design of a Hybrid Renewable Energy System for Hybrid Electric Vehicle Applications by Babu Jarapala Ramesh, Murty M.V.D.S. Krishna, Rajashekar Deva, Susheela N.

“…This article examines energy management strategies for hybrid power systems, leveraging an Artificial Neural Network (ANN) to optimize power flow based on real-time needs. The ANN controller ensures maximum power point tracking (MPPT) from renewable sources like photovoltaics (PV), wind turbines (WTs), and fuel cells (FCs), utilizing DC-DC converters. …”
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Development and Validation of a Suite of E-Probes for Electronic Diagnostic Nucleic Acid Analysis (EDNA) for 20 Graft-Transmissible Pathogens of Citrus Using MiFi and Blind Ring Te... by D. M. Nascimento, S. Bodaghi, H. Wang, M. R. Ribeiro-Junior, R. Campos, T. Dang, F. Osman, J. Habiger, A. S. Espindola, G. Vidalakis, K. F. Cardwell

“…These e-probes were optimized using the MiFi bioinformatics platform for specificity, sensitivity, and detection limits through both in silico and in planta testing. …”
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Isolation and identification of strawberry anthracnose and fungicide screening in Henan province by SUN Wenbin, ZHANG Jingjing, SONG Yanhong, ZHAO Xia, LI Gang, ZHOU Houcheng, LIU Lifeng

“…The primary biological characteristics of these isolates were examined with an emphasis on how various environmental factors, such as temperature, pH levels, carbon sources, and nitrogen sources, influenced mycelial growth. …”
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Strategi Transliterasi pada Serat Ngelmu Bumi Asia untuk Mengoptimalkan Kemahiran Membaca Aksara Jawa by Wening Pawestri, Elis Suryani Nani Sumarlina, Ahmad Undang Darsa, Bani Sudardi

“…Therefore, a study was conducted on grade X students of SMK Kita Bojonegoro to optimize Javanese script reading skills. The study was conducted using sources from ancient manuscripts and utilizing learning media to achieve optimal results. …”
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FEN-MRMGCN: A Frontend-Enhanced Network Based on Multi-Relational Modeling GCN for Bus Arrival Time Prediction by Ting Qiu, Chan-Tong Lam, Bowie Liu, Benjamin K. Ng, Xiaochen Yuan, Sio Kei Im

“…Accurate bus arrival time prediction is crucial for enhancing passenger experience and optimizing smart city transit systems. Existing methods, typically based on single-route, sparse stop data, struggle with the complex spatiotemporal interactions present in dense stop areas and multi-route networks, resulting in lower prediction accuracy. …”
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