Successful desensitization of donor-specific antibodies in a single cord blood transplant recipient by Mégane Tanguay, Sandra Cohen, Isabelle Ménard, Marie-Christine Meunier, Jean-Sébastien Delisle, Jean Roy, Olivier Veilleux, Imran Ahmad

“…Existing literature on HLA desensitization has primarily focused on haploidentical transplants, and there is a lack of experience regarding the optimal strategy in UCB transplantation.Methods: We report our successful desensitization strategy in a 42-year-old woman with acute lymphoblastic leukemia receiving a single UCB unit. …”
Get full text

Risk factors for mortality and implications on therapy for Stenotrophomonas maltophilia bacteraemia by Matthew Chung Yi Koh, Jinghao Nicholas Ngiam, Lionel Hon-Wai Lum, Nares Smitasin, Ka Lip Chew, David Michael Allen

“…Thus, we retrospectively examined the clinical presentation, microbiological characteristics, treatment options to identify risk factors for mortality. Methods: We performed a retrospective single-centre analysis of Stenotrophomonas maltophilia bacteraemia from 1 Jan 2012–30 Jun 2024. …”
Get full text

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection by Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran

“…Abstract Background Neurodegenerative diseases (NDs), including Alzheimer‘s disease, Parkinson‘s disease, and Huntington‘s disease, are complex and challenging due to their intricate pathophysiology and limited treatment options. Methods This review systematically sourced articles related to neurodegenerative diseases, neurodegeneration, quercetin, and clinical studies from primary medical databases, including Scopus, PubMed, and Web of Science. …”
Get full text

Enhanced Sliding Mode Control for Dual MPPT Systems Integrated with Three-Level T-Type PV Inverters by Farzaneh Bagheri, Jakson Bonaldo, Naki Guler, Marco Rivera, Patrick Wheeler, Rogerio Lima

“…The combination of these methods ensures faster and stable tracking under dynamic irradiance conditions. …”
Get full text

Antiparasitic and Antifungal Activities of Cetyl-Maritima, a New <i>N</i>-Cetyl-Modified Maritima Derivative by Ibrahim S. Al Nasr, Jingyi Ma, Tariq A. Khan, Waleed S. Koko, Imen Ben Abdelmalek, Rainer Schobert, Wendy van de Sande, Bernhard Biersack

“…Exemplarily, we synthetically optimized the fragrance 4-(4,8-dimethyl-3,7-nonadienyl)-pyridine, a.k.a. …”
Get full text

Interbrain synchronization in classroom during high-entropy music listening and meditation: a hyperscanning EEG study by Junling Gao, Hang Kin Leung, Kin Cheung (George) Lee, Chun Chi Poon, Gan Huang, Junhao Liao, Bonnie Wai Yan Wu, Thuan Quoc Thach, Rainbow Tin Hung Ho, Hin Hung Sik

“…IntroductionSocial interaction is a vital source of human development, yet neuroscientific research delineating its neural correlates in large groups is scarce. …”
Get full text

The therapeutic effect of antioxidant postbiotic cocktail in colitis mice: A promising approach to alleviate oxidative stress in two high-fat and normal-diet feeding mice by Niloofar Rezaie, Fahimeh Bagheri-Amiri, Shadi Aghamohammad, Shohreh Khatami, Malihe Talebi, Aria Sohrabi, Mohammad Reza Pourshafie, Mahdi Rohani

“…Therefore, in this study we aimed to assess the effectiveness of a novel postbiotic resulted from native probiotic Lactobacillus strains with robust antioxidant properties in ameliorating colitis in murine models fed with Normal-Diet or High Fat-Diet. Material and methods: Eighty-eight strains of Lactobacillus and Bifidobacterium sourced from human feces and milk were screened for antioxidant activity. …”
Get full text

Current Context of <i>Cannabis sativa</i> Cultivation and Parameters Influencing Its Development by Andreia Saragoça, Ana Cláudia Silva, Carla M. R. Varanda, Patrick Materatski, Alfonso Ortega, Ana Isabel Cordeiro, José Telo da Gama

“…This review covers key factors affecting <i>C. sativa</i> cultivation, including photoperiod, light spectrum, cultivation methods, environmental controls, and plant growth regulators. …”
Get full text

Varicose veins in the anterior accessory great saphenous vein system of the lower limb by V. I. Rusyn, F. M. Pavuk, M. I. Borsenko, N. M. Popovych, V. V. Rusyn

“…In order to improve the results of the treatment of patients with varicose veins and to prevent the recurrence of the disease, a quantitative analysis of the types of varicose veins in the anterior accessory great saphenous vein (GSV) system should be carried out according to the source of their reflux. Materials and methods. …”
Get full text

Strategi komunikasi Dinas Sosial Kabupaten Sleman dalam mengoptimalkan pelaksanaan program lanjut usia terlantar di Sendangmulyo by Nadia Zulva Pratiwi, Novianto Yudha Laksana

“…This study uses a descriptive qualitative approach. Data collection methods used are observation, structured interviews and documentation. …”
Get full text

Design and Evaluation of a Portable Pinhole SPECT System for ¹⁷⁷Lu Imaging: Monte Carlo Simulations and Experimental Study by Georgios Savvidis, Vasileios Eleftheriadis, Valentina Paneta, Eleftherios Fysikopoulos, Maria Georgiou, Efthimis Lamprou, Sofia Lagoumtzi, George Loudos, Paraskevi Katsakiori, George C. Kagadis, Panagiotis Papadimitroulas

“…The purpose of this study was to evaluate the technical parameters for developing a prototype portable gamma camera dedicated to ¹⁷⁷Lu imaging applications. <b>Methods</b>: The well-validated GATE Monte Carlo toolkit was used to study the characteristics of the system and evaluate its performance in terms of spatial resolution, sensitivity, and image quality. …”
Get full text

Study on Dust Hazard Levels and Dust Suppression Technologies in Cabins of Typical Mining Equipment in Large Open-Pit Coal Mines in China by Xiaoliang Jiao, Wei Zhou, Junpeng Zhu, Xinlu Zhao, Junlong Yan, Ruixin Wang, Yaning Li, Xiang Lu

“…Field measurements and statistical methods revealed temporal–spatial variation patterns of dust concentrations, quantifying occupational exposure risks and providing theoretical foundations for dust control. …”
Get full text

Adeno-Associated Virus-Engineered Umbilical Cord-Derived Mesenchymal Stromal Cells Overexpressing Human sFlt-1 for Anti-Angiogenesis by Ewa Yee-Wa Choy, Chee-Onn Leong, Soon-Keng Cheong, Khong-Lek Then, Kong-Yong Then

“…Umbilical cord-derived MSCs are an attractive cell source due to their easy accessibility and potential for genetic modification. …”
Get full text

Genotypic and Environmental Impacts on Vicine and Convicine Concentrations in Faba Beans by Pankaj Maharjan, Aaron C. Elkins, Jason Brand, Samuel C. Catt, Simone J. Rochfort, Joe F. Panozzo

“…High concentrations of vicine and convicine (v-c) in faba beans can trigger favism in susceptible humans, posing a significant barrier to the broader adoption of faba beans as a food source. While plant breeding and various post-harvest processing methods have been adopted to reduce v-c levels, there is limited understanding of how agronomic practices may assist in reducing v-c levels. …”
Get full text

Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv... by Farhad Sharifi Bagha, Jafar Haqiqat, Zahra Karimi Takanloo

“…Therefore, using 96 variables of seasonal time series data affecting the management quality index within the bank productivity approach which is one of the most important indicators of assessing the health of the banking system, and employing the factor-added empirical model (FAVAR), the effect of monetary policy via the exchange rate channel on the management quality index in the banking system was investigated during the period of 1378:1-1401:4</p> <p style="text-align: left;">In order to investigate the mechanism of the impact of monetary policy shocks via exchange rate channel on the variables affecting the health of the banking system, the two-stage method of principal components was used. Therefore, first, the following equation was estimated without considering the Yt vector, based on which the number of optimal factors was selected. …”
Get full text

Enhancing Voice Activity Detection for an Elderly-Centric Self-Learning Conversational Robot Partner in Noisy Environments by Subashkumar Rajanayagam, Max Andreas Ingrisch, Pascal Müller, Patrick Jahn, Stefan Twieg

“…In contrast, traditional lightweight rule-based VAD methods tend to yield higher recall but at the expense of precision. …”
Get full text

Associations between Life’s Essential Eight cardiovascular health metrics and cardiovascular mortality risk across frailty statuses: evidence from a UK Biobank cohort study by Lirong Chai, Kai Zhang, Yi Zhang, Weijing Wang, Dongfeng Zhang, Junning Fan

“…Therefore, we aimed to assess the association between LE8 and CVD mortality among individuals with different frailty status.MethodsData were sourced from the UK Biobank of 439,462 participants aged 37–73 years. …”
Get full text

Comparative efficacy and safety in low-intensity treatment for acute myeloid leukemia in older patients: a systematic review and network meta-analysis by Wenze Li, Sijing Kang, Yu Jiao, Pengjie Yue, Weilin Dong, Rui Ge, Ziyi Wang, Xiaojing Yan

“…Despite the increasing number of randomized clinical trials (RCTs) and cohort studies in this area, the optimal treatment approach remains unclear. Methods We sourced four databases, PubMed, Embase, Cochrane, and Web of Science, until July 07, 2024, to identify all Phase II/III randomized controlled trials (RCTs) and cohort studies evaluating low-intensity treatments for older AML patients. …”
Get full text

Comparison of different magnetic resonance cholangiography techniques in living liver donors including Gd-EOB-DTPA enhanced T1-weighted sequences. by Sonja Kinner, Verena Steinweg, Stefan Maderwald, Arnold Radtke, Georgios Sotiropoulos, Michael Forsting, Tobias Schroeder

“…Aim of this study was to compare T2-weighted (T2w) and Gd-EOB-DTPA enhanced T1-weighted (T1w) magnetic resonance cholangiography (MRC) techniques in the evaluation of PLLDs.<h4>Materials and methods</h4>30 PLLDs underwent MRC on a 1.5 T Magnetom Avanto (Siemens, Erlangen, Germany) using (A) 2D T2w HASTE (Half Fourier Acquisition Single Shot Turbo Spin Echo) fat saturated (fs) in axial plane, (B) 2D T2w HASTE fs thick slices in coronal plane, (C) free breathing 3D T2w TSE (turbo spin echo) RESTORE (high-resolution navigator corrected) plus (D) maximum intensity projections (MIPs), (E) T2w SPACE (sampling perfection with application optimized contrasts using different flip angle evolutions) plus (F) MIPs and (G) T2w TSE BLADE as well as Gd-EOB-DTPA T1w images without (G) and with (H) inversion recovery. …”
Get full text

Vision Transformer-Based Unhealthy Tree Crown Detection in Mixed Northeastern US Forests and Evaluation of Annotation Uncertainty by Durga Joshi, Chandi Witharana

“…By comparing the performance of traditional convolutional neural network (CNN) models (U-Net and DeepLabv3+) with a state-of-the-art Vision Transformer (SegFormer), we aimed to determine the optimal approach for detecting unhealthy tree crowns (UTC) using a publicly available data source. …”
Get full text