Assessing developability early in the discovery process for novel biologics by Monica L. Fernández-Quintero, Anne Ljungars, Franz Waibl, Victor Greiff, Jan Terje Andersen, Torleif T. Gjølberg, Timothy P. Jenkins, Bjørn Gunnar Voldborg, Lise Marie Grav, Sandeep Kumar, Guy Georges, Hubert Kettenberger, Klaus R. Liedl, Peter M. Tessier, John McCafferty, Andreas H. Laustsen

“…We furthermore present in silico, in vitro, and in vivo methods and techniques that can be exploited at different stages of the discovery process to identify molecules with liabilities and thereby facilitate the selection of the most optimal drug leads. …”
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A Review of Oscillators in Hydrokinetic Energy Harnessing Through Vortex-Induced Vibrations by Deping Cao, Jie He, Hanqi Zeng, Yijia Zhu, Sean Zixuan Chan, Mark Ravinpal Williams, Ivan Zhi Liang Khor, Omkar Venkata Yalla, Mohammed R. Sunny, Ritwik Ghoshal, Anirban Bhattacharyya, Swapnadip De Chowdhury, Zaibin Lin, Cheng Siong Chin, Hao Chen

“…The review provides insights into the geometric configurations, material properties, and advanced computational methods that are pivotal in this optimisation process. …”
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Influence of low-intensity artificial light on the fatty acid profile of the biotechnologically important culinary mushroom Pleurotus eryngii in vitro by Oksana Mykchaylova, Aleksander Besarab, Anatoliy Negriyko, Margarita Lomberg, Natalia Poyedinok

“…This study aimed to compare and evaluate the fatty acid profile and fat quality indices of lipids from the mycelial mass of Pleurotus eryngii under various light-emitting diode (LED) and laser light irradiation regimes. Methods To determine the effect of artificial light on the biosynthetic activity of P. eryngii, an artificial lighting system based on LED matrices with wavelengths of 470 nm (blue), 530 nm (green), and 650 nm (red), as well as an argon gas laser as a coherent visible light source at 488 nm, was used. …”
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Regional disparities and influencing factors of health production efficiency: evidence from China by Hongwei Li, Ruixin Wang, Hongliang Wang

“…This paper evaluates health production efficiency in China, analyzes regional disparities, and explores influencing factors. Methods After constructing an evaluation index system for residents' health production efficiency, this study employs the undesired output-SBM super-efficiency model to measure health production efficiency. …”
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Enhancing patient education on the role of tibial osteotomy in the management of knee osteoarthritis using a customized ChatGPT: a readability and quality assessment by Stephen Fahy, Stephan Oehme, Danko Dan Milinkovic, Benjamin Bartek

“…This study assessed whether a customised ChatGPT could be utilized to improve readability and source accuracy in patient education on Knee OA and tibial osteotomy.MethodsCommonly asked questions about HTO were gathered using Google's “People Also Asked” feature and formatted to an 8th-grade reading level. …”
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A systematic review on the relationship between marine pollution and human health in small island developing states by Alisha Morsella, Carolina Castagna, Rosaria Messina, Nicolò Scarsi, Walter Ricciardi, Chiara Cadeddu

“…Methods: This review follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. …”
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An Opposition-Based Great Wall Construction Metaheuristic Algorithm With Gaussian Mutation for Feature Selection by Farouq Zitouni, Abdulaziz S. Almazyad, Guojiang Xiong, Ali Wagdy Mohamed, Saad Harous

“…Its complexity arises from the vast search space, necessitating the application of metaheuristic methods to efficiently identify optimal feature subsets. …”
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IMPLEMENTASI APLIKASI TAPROSE TEMANKU HUMAS KOMINFO KABUPATEN TIBAN by Early Azza Bening Brillianti, Pratiwi Wahyu Widiarti

“…This study used descriptive method with a qualitative approach. In determining the informants, researcher uses purposive sampling techniques. …”
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Isolation and identification of an alginate lyase-producing marine bacterium strain and its enzymological characteristics by TANG Haiqing, OU Changrong, ZHENG Xiaodong

“…The enzymological characteristics of alginate lyase from the strain QZ-4 were determined by ultraviolet (UV) method, including the optimal temperature, pH, thermal and pH stability, metal ions and ethylene diamine tetraacetic acid (EDTA) tolerance, etc.The results showed that the strain QZ-4 was a Gram-negative rod bacterium. …”
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DeepSARFlood: Rapid and automated SAR-based flood inundation mapping using vision transformer-based deep ensembles with uncertainty estimates by Nirdesh Kumar Sharma, Manabendra Saharia

“…However, SAR data remains underutilized due to less availability of training data, and reliance on labor-intensive manual or semi-automated change detection methods. This study introduces a novel end-to-end methodology for generating SAR-based flood inundation maps, by training deep learning models on weak flood labels generated from concurrent optical imagery. …”
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Rapid Analysis of Heavy Metal Element Adsorption by SCG Based on LIBS Technology by Xie Hairui, You Libing, Fang Xiaodong, Li Leyi, Ding Haokai, Zhou Zhengqi, Zhang Guanyang, Zhang Dongjian

“…However, most elemental analysis methods have complex pretreatment procedures and are time-consuming, making real-time analysis difficult to achieve. …”
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Enhancing DeepLabv3+ Convolutional Neural Network Model for Precise Apple Orchard Identification Using GF-6 Remote Sensing Images and PIE-Engine Cloud Platform by Guining Gao, Zhihan Chen, Yicheng Wei, Xicun Zhu, Xinyang Yu

“…The innovation of this research lies in combining image annotation and object-oriented methods during training, improving annotation efficiency and accuracy. …”
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Frequency-Aware Diffusion Model for Multi-Modal MRI Image Synthesis by Mingfeng Jiang, Peihang Jia, Xin Huang, Zihan Yuan, Dongsheng Ruan, Feng Liu, Ling Xia

“…While recent advances in diffusion models (DMs) show potential for high-quality image translation, existing methods still struggle to preserve fine structural details and ensure accurate image synthesis in medical imaging. …”
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EGFR and K-ras Mutation Analysis in Non-Small Cell Lung Cancer: Comparison of Paraffin Embedded versus Frozen Specimens by Mariëlle I. Gallegos Ruiz, Karijn Floor, Frank Rijmen, Katrien Grünberg, José A Rodriguez, Giuseppe Giaccone

“…Although frozen tumor tissue would probably be the optimal source for analysis, the most common source of tumor material is fixed and paraffin embedded (FPE) archival specimens. …”
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Child feces disposal practices in rural Orissa: a cross sectional study. by Fiona Majorin, Matthew C Freeman, Sharmani Barnard, Parimita Routray, Sophie Boisson, Thomas Clasen

“…While large-scale programs in some countries have increased latrine coverage, they sometimes fail to ensure optimal latrine use, including the safe disposal of child feces, a significant source of exposure to fecal pathogens. …”
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Arsenic, Cadmium, Lead, and Aluminium Concentrations in Human Milk at Early Stages of Lactation by Hai-Hsuan Chao, Chih-Hung Guo, Chung-Bin Huang, Pei-Chung Chen, Hsiu-Chuan Li, Der-Yun Hsiung, Yu-Kung Chou

“…Human milk is considered to be the best nutrition for all infants because it provides the optimal source of nutritional, immunological, developmental, psychological, economic, practical, and environmental benefits in both the short and long terms. …”
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Alactic base excess is not a sensitive or specific diagnostic tool for outcome in horses with colic by Corinne E. Crosby, Annette O’Connor, Amelia S. Munsterman

“…IntroductionColic is a significant source of morbidity and mortality in horses, and no single biomarker can distinguish surgical from medical colic or predict mortality. …”
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Effect of Capsular Tension Ring on Refractive and Morphological Outcomes in Pseudoexfoliative Eyes by Cunha B, Gil P, Rodrigues Alves N, Hipólito-Fernandes D, Maduro V, Feijão J, Alves N

“…Postoperative refractive PE was calculated using an optimized A-constant and the Kane formula.Results: A total of 25 eyes were included in each group. …”
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A longitudinal investigation of gut microbiota dynamics in laying hens from birth to egg-laying stages by Seojin Choi, Eun Bae Kim

“…Methods A total of 100 Hy-Line Brown laying hens were reared under controlled conditions, and feces and ileal contents were collected at three post-laying stages (151, 302, and 422 days). …”
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Evaluation of cholera surveillance system, Kumasi Metropolis, Ashanti Region, Ghana, 2020 by Belinda Nsiah Opoku, Ebenezer Kofi Mensah, Joseph Asamoah Frimpong, Delia Akosua Bandoh, Gyesi Razak Issahaku, Ernest Kenu

“…We evaluated the cholera surveillance system in Ghana’s second most populated city – Kumasi metropolis, to determine whether the system is meeting its objectives, and assessed its attributes and usefulness. Methods: We reviewed 2015-2019 cholera surveillance data sourced from health facilities and the health directorate of the Kumasi Metropolis. …”
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