ECONOMIC AND LEGAL PREREQUISITES FOR THE FUNCTIONING OF STARTUPS IN MODERN SOCIETY: ISSUES OF INTERNATIONAL AND NATIONAL LEGAL REGIMES by Viktor Makovii, Rashad Mamedov, Illia Klochko

“…Its primary objective is to ensure the most optimal and effective utilisation of available and accessible resources, which are inherently limited in the modern context. …”
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Efficacy and safety of oxaliplatin-based chemotherapy as first-line treatment in elderly patients with metastatic colorectal cancer: a meta-analysis by Shaoqing Fan, Zeming Zhao, Haiqian Wang, Handong Wang, Wenbo Niu

“…Subgroup analyses explored heterogeneity sources, including chemotherapy combinations (e.g., bevacizumab, panitumumab).ResultsSeven RCTs (1,839 patients) met inclusion criteria. …”
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Midazolam infusions for therapeutic management of pediatric refractory status epilepticus: a systematic review by K. Taneille Johnson, Ammar AlZadjali, Dawoud Al Nasseri, Jessie Cunningham, Kazuhiro Shoya, Cecil D. Hahn, Cecil D. Hahn, Cecil D. Hahn, John Basmaji, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon

“…ObjectiveWe aim to determine the optimal dosing of midazolam continuous intravenous infusions for the treatment of pediatric refractory status epilepticus (RSE).Data sourcesWe searched Medline ALL, Embase, Embase Classic, Cochrane CENTRAL, and Web of Science in March 2023 and again in February 2024.Study selectionRandomized and non-randomized studies involving pediatric patients who received continuous midazolam for the treatment of RSE were eligible. …”
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An eHealth Intervention to Improve Quality of Life, Socioemotional, and Health-Related Measures Among Older Adults With Multiple Chronic Conditions: Randomized Controlled Trial by David H Gustafson Sr, Marie-Louise Mares, Darcie Johnston, Olivia J Vjorn, John J Curtin, Gina Landucci, Klaren Pe-Romashko, David H Gustafson Jr, Dhavan V Shah

“…Tested moderators were sex, scheduled health care use, and number of chronic conditions. Data sources were surveys at baseline and 6 and 12 months comprising validated scales, and continuously collected ElderTree usage. …”
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Effects of virtual reality-based interventions on cognitive function, emotional state, and quality of life in patients with mild cognitive impairment: a meta-analysis by Xiaohan Li, Yuting Zhang, Lifeng Tang, Lifeng Tang, Lin Ye, Min Tang

“…To investigate potential sources of heterogeneity, subgroup analyses and meta-regression were conducted. …”
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Potential evaluation and development utilization technology of geothermal resources in the Jining Coalfield by Qipeng SHI, Jianguo FAN, Fengfeng SHI, Xuesen WANG, Huiming ZHENG, Jia MENG, Shuailiang SONG

“…Under the guidance of China’s “carbon peaking and carbon neutrality” goals, efforts are underway to optimize and adjust the national energy structure. …”
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Program Report—Transplant Manitoba Adult Kidney Program Cutting Costs, Not Corners: Value of Quality Improvement Initiatives by Christie Rampersad, Aaron Trachtenberg, James Shaw, Nancy Dodd, Krista Maxwell, Martin Karpinski, Chris Wiebe, Peter Nickerson, Julie Ho

“…Methods: To quantify the potential cost savings, we employed a 3-pronged approach. …”
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High-throughput screening of monoclonal antibodies against carbapenemases using a multiplex protein microarray platform by Sascha D. Braun, Sascha D. Braun, Martin Reinicke, Martin Reinicke, Celia Diezel, Celia Diezel, Elke Müller, Elke Müller, Katrin Frankenfeld, Thomas Schumacher, Hugo Arends, Stefan Monecke, Stefan Monecke, Ralf Ehricht, Ralf Ehricht, Ralf Ehricht

“…However, the development of such assays is often hindered by the time-consuming process of identifying high-affinity antibody pairs.MethodsTo accelerate this process, we evaluated a protein microarray platform as a high-throughput screening tool to identify optimal monoclonal antibody (mAb) pairs targeting the most clinically relevant carbapenemases. …”
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Substantiation of Principles and Effectiveness of Advanced Complex Differentiated Treatment of Circulatory System Organs Affections in Patients With Liver Cirrhosis by Farmaha M., Abrahamovych M., Svintsitskyi A., Abrahamovych O.

“…To compare the treatment effectiveness of patients with cirrhotic cardiomyopathy and arterial hypotension, they were divided in a randomized way into two groups: experimental, treated with the help of our modified method, and control one, treated with the standard method. …”
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The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation by Guoli Huai, Yong Wang, Jiaxiang Du, Zhenhui Cheng, Yuxuan Xie, Jia Zhou, Hongmei Tang, Yanyan Jiang, Xiangyang Xing, Shaoping Deng, Dengke Pan, Dengke Pan, Dengke Pan

“…IntroductionGenetically edited pigs, modified using CRISPR-Cas9 technology, hold promise as potential sources for xenotransplantation. However, the optimal combination of genetic modifications and their expression levels for initial clinical trials remains unclear. …”
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A Feasibility Study for Clinical Implementation of hypo fractionated SBRT Program at a Clinic in an LMIC Using Locally Designed Lung Phantom by Abigail N.M. Quaye, MPhil, Eric C.D.K. Addison, PhD, Ernest Osei, PhD, Afua A. Yorke, PhD

“…The goal is to alleviate the burden on patients and health care providers, particularly in the context of limited resources. Methods and Materials: A lung phantom was designed from locally sourced materials consisting of wood slabs to mimic the lung, a perspex tank filled with water for tissue equivalence, and a 3-cm diameter acrylic ball to simulate the tumor. …”
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Effects of taurine on growth performance, body composition and physiological responses of western white shrimp, Litopenaeus vannamei broodstock by Vahid Morshedi, Mahmoud Nafisi Bahabadi, Mansour Torfi Mozanzadeh, Amin Oujifard, Naser Agh, Khalegh Maneii, Ahmad Qasemi, Nehzat Bakhshi, Hadi Ebrahimi, Rezvan Tamadoni, Shirin Hamedi, Reza Bagherpour, Fatemeh Solimani

“…In aquaculture, the balance of nutrients in the diet of aquatic animals guarantees optimal growth and health improvement. Taurine (Tau = 2-aminoethanesulfonic acid) is an amino sulfonic acid, which has been proven to be conditionally essential for some aquatic animals when these animals are fed with diets containing high plant protein levels, due to taurine deficiency in plant-based protein sources. …”
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Pregnancy outcomes following surgical repair of female genital fistula in UgandaAJOG Global Reports at a Glance by Abner P. Korn, MD, Justus K. Barageine, PhD, Hadija Nalubwama, MPH, Jaffer Okiring, PhD, Florence Nalubega, MMed, Shane Ian Asiimwe, MMed, Alphonsus Matovu, MMed, Alison M. El Ayadi, ScD

“…We compared outcomes to two external data sources: a meta-analysis and propensity-score matched Ugandan women of reproductive-age. …”
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Advances in Minimally Invasive Treatments for Prostate Cancer: A review of the Role of Ultrasound Therapy and Laser therapy by Corneliu-Dan Blendea, Mohammad Tazim Khan, Marius Stoian, Teodor Claudiu Ion Gligore, Ștefan Cuculici, Ion Lucian Stanciu, Mirela Gabriela-Irina Protosevici, Marius Iordache, Anca Buliman, Carmen Costea-Firan, Ioana Simona Cazacu, Liviu-Constantin Iordache, Doroteea Teoibaș-Șerban

“…While promising for both primary and salvage settings, ongoing research and technological refinements are crucial to optimize their efficacy and expand their clinical utility. …”
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Genetic diversity analysis and core collection construction of Phyllanthus emblica based on SSR markers by WANG Jianchao, ZHANG Xiaoyan, ZHANG Lijie, LI Tao, XIE Lixue

“…The core collection of P. emblica was constructed using the optimal scheme of Jaccard genetic distance, class average method, and priority sampling strategy. …”
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Establishment of jujube anther culture and plant regeneration system by GUO Kaiwen, XU Chongchong, HU Yaning, HUANG Jian

“…In this study, three jujube varieties, Dongzao, Junzao and Qiyuexian, were used as materials. By optimizing the ratios of plant growth regulators, carbon sources, and cultivation conditions, an efficient anther culture regeneration system was established. …”
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Emission Characteristics of Concrete Mixer Trucks Under Real-world Operating Conditions by Xinbo SHI, Yao CHEN, Jin LI, Peixuan LI, Zihang ZHOU, Bin WANG, Xue CHEN

“…Therefore, conducting emission studies based on real-world conditions is essential for analyzing emission variations under different operating scenarios and for effectively controlling emissions from mobile sources.Methods This study selected concrete mixer trucks with high activity levels and representative operating areas in Chengdu to investigate the real emission characteristics of these vehicles during actual task processes. …”
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Toward a Domain-Overarching Metadata Schema for Making Health Research Studies FAIR (Findable, Accessible, Interoperable, and Reusable): Development of the NFDI4Health Metadata Sch... by Haitham Abaza, Aliaksandra Shutsko, Sophie A I Klopfenstein, Carina N Vorisek, Carsten Oliver Schmidt, Claudia Brünings-Kuppe, Vera Clemens, Johannes Darms, Sabine Hanß, Timm Intemann, Franziska Jannasch, Elisa Kasbohm, Birte Lindstädt, Matthias Löbe, Katharina Nimptsch, Ute Nöthlings, Marisabel Gonzalez Ocanto, Tracy Bonsu Osei, Ines Perrar, Manuela Peters, Tobias Pischon, Ulrich Sax, Matthias B Schulze, Florian Schwarz, Carolina Schwedhelm, Sylvia Thun, Dagmar Waltemath, Hannes Wünsche, Atinkut A Zeleke, Wolfgang Müller, Martin Golebiewski

“…The National Research Data Infrastructure for Personal Health Data (NFDI4Health) seeks to optimize data sharing among the clinical, epidemiological, and public health research communities while preserving privacy and ethical regulations. …”
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Development and validation of an interpretable multi-task model to predict outcomes in patients with rhabdomyolysis: a multicenter retrospective cohort studyResearch in context by Chunli Liu, Jie Shi, Fengjuan Wang, Duo Li, Yu Luo, Bofan Yang, Yunlong Zhao, Li Zhang, Dingwei Yang, Heng Jin, Jie Song, Xiaoqin Guo, Haojun Fan, Qi Lv

“…Methods: We conducted a retrospective study using three data sources: the eICU Collaborative Research Database (eICU-CRD), the Medical Information Mart for Intensive Care IV (MIMIC-IV), and electronic medical records from four tertiary hospitals in China. …”
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Advances in studies and applications of thick diamond films prepared by microwave plasma chemical vapor deposition by Fucheng LIU, Guanjie MA, Jiangtao HUANG, Zongyan ZHANG, Peigang HAN, Bin HE

“…Compared to other chemical vapor deposition (CVD) methods, the microwave plasma chemical vapor deposition (MPCVD) method is recognized as the best technology for depositing high-quality diamond films. …”
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