CardioGenAI: a machine learning-based framework for re-engineering drugs for reduced hERG liability by Gregory W. Kyro, Matthew T. Martin, Eric D. Watt, Victor S. Batista

“…It is therefore of tremendous interest to develop advanced methods for identifying hERG-active compounds in the early stages of drug development, as well as for proposing redesigned compounds with reduced hERG liability and preserved primary pharmacology. …”
Get full text

TSMixer- and Transfer Learning-Based Highly Reliable Prediction with Short-Term Time Series Data in Small-Scale Solar Power Generation Systems by Younjeong Lee, Jongpil Jeong

Get full text

Analysis on ignition characteristics and stability of large length-diameter tube with high-low pressure chamber: Experimental and two-phase flow method research by Shenshen Cheng, Ruyi Tao, Xinggan Lu, Xiaoting Cui, Shao Xue

Get full text

Evaluating and enhancing the service capacity of secondary public hospitals in urban China: a multi-method empirical analysis based on Guangzhou (2019–2023) by Baoling Wu, Baoling Wu, Wenbo Wu, Xi Wang, Weizhang Huang, Zhenni Luo, Jifeng Li

“…This study aims to systematically evaluate the evolution and spatial dynamics of service capacity among secondary general public hospitals in Guangzhou, offering empirical evidence to support capacity improvement and policy optimization.MethodsA composite evaluation framework was constructed across three dimensions: medical quality, operational efficiency, and sustainability. …”
Get full text

OPTIMIZING LONG TEXT CLASSIFICATION PERFORMANCE THROUGH KEYWORD-BASED SENTENCE SELECTION: A CASE STUDY ON ONLINE NEWS CLASSIFICATION FOR INDONESIAN GDP GROWTH-RATE DETECTION by Dinda Pusparahmi Sholawatunnisa, Lya Hulliyyatus Suadaa

Get full text

Do optimal prognostic thresholds in continuous physiological variables really exist? Analysis of origin of apparent thresholds, with systematic review for peak oxygen consumption,... by Alberto Giannoni, Resham Baruah, Tora Leong, Michaela B Rehman, Luigi Emilio Pastormerlo, Frank E Harrell, Andrew J S Coats, Darrel P Francis

“…<h4>Methods</h4>First, we examined studies testing pVO2, EF or BNP prognostic thresholds. …”
Get full text

Comparative analysis of phytochemicals and antioxidant activities in seeds and sprouts of different varieties of radish (Raphanus sativus L.): TOPSIS-entropy weight method by Caihui Guo, Yi Zhu

“…The ultimate goal was to identify the optimal radish variety with these beneficial properties through the TOPSIS-entropy weight method. …”
Get full text

Study of mechanical and physical properties of pineapple leaf fiber and coffee husk filler reinforced polymer composite using response surface method by Kinisa Wareso Abesho, Moera Gutu Jiru, Hirpa G. Lemu, Mohammed Abdulkedir Alfeki

“…This study fabricates composite samples using the hand layup method, and the Response Surface Methodology is used to optimize the experimental design. …”
Get full text

How to realize large-scale outdoor thermal comfort studies? A systematic review based on OTC characterization, methods and research trends by Yuan Li, Yuan Li, Yuan Li, Wenyi Fei, Wenyi Fei, Mengsheng Yang, Mengsheng Yang, Yingfeng Wang, Yingfeng Wang, Yanan Du, Yanan Du, Yaomei Wang, Yaomei Wang

“…However, previous OTC studies have been dominated by empirical case studies of regional sample points and have lacked systematic large-scale exploration within a certain region.MethodsThis study used the preferred reporting items for systematic reviews and meta-analyses (PRISMA) method and bibliometric tools to statisticians the sources, keywords, content and highly cited papers of OTC studies.ResultsBased on the quantitative results, this study sorts and organizes OTC research from characterization, methods, and research trends, and summarizes the following results: (1) Universal thermal climate index (UTCI) is relatively suitable for large-scale OTC research; (2) The combination of subjectivity and objectivity with the application of Artificial Intelligence (AI) is the current cutting-edge research method of OTC; (3) Local climate zone (LCZ) classification system has a potential to be used in future large-scale OTC research has application potential.DiscussionBased on the collated results of previous studies, this study proposes a framework for large-scale OTC study to provide necessary theoretical support and practical guidance for future urban planning and construction, which will help optimize the urban environment and improve the thermal comfort and quality of life of residents.…”
Get full text

Reproductive, maternal, newborn, child and adolescent health services in humanitarian and fragile settings: A mixed methods study of midwives' and women's experiences. by T Dey, M G Shah, A Baba, N Mugo, T Thommesen, V Vivilaki, M Boniol, N Alam, M Dibley, D Okoro, P Tenhoope-Bender, T Triantafyllou, E V Langlois

“…Guided by an expert committee, a concurrent mixed methods approach was applied, using secondary analysis of primary quantitative and qualitative data sources. …”
Get full text

A rapid review of adolescent engagement in massive open online courses (MOOCS) in health and education: Content, engagement strategies and evaluation methods by Putu Novi Arfirsta Dharmayani, Allyson R. Todd, Jennifer Dam, Josephine Y. Chau, Sara Wardak, Katrina E. Champion, Seema Mihrshahi, Stephanie R. Partridge

“…Facilitators of MOOC engagement included personal interest and a sense of achievement, whereas barriers included using technical language, lack of visual and graphic content, and lack of interaction. Evaluation methods predominantly used multiple sources, with self-reported surveys being the most common. …”
Get full text

Real-Time Evaluation of Ground Insulation Degradation and Fault Warning Method Under Multiple Operating Conditions for Train Traction Drive System by Zhenglin Cheng, Kan Liu, Xueming Li, Shaolong Xu, Zhiwen Chen, Fengbing Jiang

“…Combined with on-site fault case data, a decision tree method is used to establish a classification model between the feature index set and typical grounding fault sources under different operating conditions, which is then converted into a fault diagnosis rule library. …”
Get full text

The impact of the technical decisions made in the operation of energy systems in Tashkent city by Y. N. Zvonareva, R. V. Akhmetova, K. I. Tursunov, I. R. Shorohov

“…Development and testing at a real facility of an integrated approach to the modernization of heat supply systems, taking into account the introduction of modern energy-saving technologies to reduce costs and optimize the processes of generation and consumption of thermal energy.METHODS. …”
Get full text

Fast Catalog Matching for Improved Posteriors via Constrained Clustering by Jacob Feitelberg, Tamás Budavári, Amitabh Basu

“…Our new approach uses constrained clustering, specifically COP-KMeans, to provide near-optimal solutions in a fraction of the time of previous methods. …”
Get full text

Multi-Stress Accelerated Degradation Testing Reliability Assessment of LED Lamp Beads Considering Generalized Coupling by Yinglong Dong, Zhen Zhou, Kaixin Liu, Xu Yang

Get full text

Construction of an Ecological Security Structure in Fuzhou City of Jiangxi Provicne Based on an MCR Model by Chen Qun, Liu Pinghui, Zhu Chuanmin

“…[Methods] Fuzhou City of Jiangxi Provicne was used as a research area. …”
Get full text

Siamese Graph Convolutional Split-Attention Network with NLP based Social Sentimental Data for enhanced stock price predictions by Jayaraman Kumarappan, Elakkiya Rajasekar, Subramaniyaswamy Vairavasundaram, Ketan Kotecha, Ambarish Kulkarni

“…Two data sources feed the model: specifically, NIFTY-50 Stock Market and real-time Twitter sentiment. …”
Get full text

Research on Pose Error Modeling and Compensation of Posture Adjustment Mechanism Based on WOA-RBF Neural Network by Hongyu Shen, Honggen Zhou, Yiyang Jin, Lei Li, Bo Deng, Jiawei Xu

“…Therefore, a compensation method based on the whale optimization algorithm optimized radial basis function neural network is proposed. …”
Get full text

Dark Ship Detection via Optical and SAR Collaboration: An Improved Multi-Feature Association Method Between Remote Sensing Images and AIS Data by Fan Li, Kun Yu, Chao Yuan, Yichen Tian, Guang Yang, Kai Yin, Youguang Li

“…Subsequently, an advanced JVC global optimization algorithm is employed to ensure high-precision association in dense scenes. …”
Get full text

An interpretable framework for risk management in TBM excavation using expert elicitation integrated with fuzzy set theory by Kibeom Kwon, Minkyu Kang, Young Jin Shin, Byoungcheol Ahn, Hangseok Choi

“…This study proposes an interpretable risk management method that effectively addresses these uncertainties and concurrent sources. …”
Get full text