Is the Existing Measles Vaccination Schedule in the Russian Federation Effective? by O. V. Tsvirkun, A. G. Gerasimova, N. V. Turaeva, N. T. Tikhonova, A. A. Melnikova, A. A. Vatolina

“…The aim of this study is to assess the importance of measles in the epidemic process of children under the age of 1 year during the elimination of infection, the effectiveness of the current measles vaccination regimen.Materials and methods. The measles incidence in children under 1 year of age was analyzed in absolute and relative terms for the period from 2010 to 2024. …”
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High-throughput screening of monoclonal antibodies against carbapenemases using a multiplex protein microarray platform by Sascha D. Braun, Sascha D. Braun, Martin Reinicke, Martin Reinicke, Celia Diezel, Celia Diezel, Elke Müller, Elke Müller, Katrin Frankenfeld, Thomas Schumacher, Hugo Arends, Stefan Monecke, Stefan Monecke, Ralf Ehricht, Ralf Ehricht, Ralf Ehricht

“…However, the development of such assays is often hindered by the time-consuming process of identifying high-affinity antibody pairs.MethodsTo accelerate this process, we evaluated a protein microarray platform as a high-throughput screening tool to identify optimal monoclonal antibody (mAb) pairs targeting the most clinically relevant carbapenemases. …”
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Performance and Cost-Effectiveness of Computed Tomography Lung Cancer Screening Scenarios in a Population-Based Setting: A Microsimulation Modeling Analysis in Ontario, Canada. by Kevin Ten Haaf, Martin C Tammemägi, Susan J Bondy, Carlijn M van der Aalst, Sumei Gu, S Elizabeth McGregor, Garth Nicholas, Harry J de Koning, Lawrence F Paszat

“…Therefore, the objective of this study was to estimate the cost-effectiveness of lung cancer screening in a population-based setting in Ontario, Canada, and evaluate the effects of screening eligibility criteria.<h4>Methods and findings</h4>This study used microsimulation modeling informed by various data sources, including the Ontario Health Insurance Plan (OHIP), Ontario Cancer Registry, smoking behavior surveys, and the NLST. …”
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Efficacy and safety of oxaliplatin-based chemotherapy as first-line treatment in elderly patients with metastatic colorectal cancer: a meta-analysis by Shaoqing Fan, Zeming Zhao, Haiqian Wang, Handong Wang, Wenbo Niu

“…Subgroup analyses explored heterogeneity sources, including chemotherapy combinations (e.g., bevacizumab, panitumumab).ResultsSeven RCTs (1,839 patients) met inclusion criteria. …”
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Midazolam infusions for therapeutic management of pediatric refractory status epilepticus: a systematic review by K. Taneille Johnson, Ammar AlZadjali, Dawoud Al Nasseri, Jessie Cunningham, Kazuhiro Shoya, Cecil D. Hahn, Cecil D. Hahn, Cecil D. Hahn, John Basmaji, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon

“…ObjectiveWe aim to determine the optimal dosing of midazolam continuous intravenous infusions for the treatment of pediatric refractory status epilepticus (RSE).Data sourcesWe searched Medline ALL, Embase, Embase Classic, Cochrane CENTRAL, and Web of Science in March 2023 and again in February 2024.Study selectionRandomized and non-randomized studies involving pediatric patients who received continuous midazolam for the treatment of RSE were eligible. …”
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An eHealth Intervention to Improve Quality of Life, Socioemotional, and Health-Related Measures Among Older Adults With Multiple Chronic Conditions: Randomized Controlled Trial by David H Gustafson Sr, Marie-Louise Mares, Darcie Johnston, Olivia J Vjorn, John J Curtin, Gina Landucci, Klaren Pe-Romashko, David H Gustafson Jr, Dhavan V Shah

“…Tested moderators were sex, scheduled health care use, and number of chronic conditions. Data sources were surveys at baseline and 6 and 12 months comprising validated scales, and continuously collected ElderTree usage. …”
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Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT by Neil McHugh, Laura Bojke, Mel Brooke Turfrey, Rachel Charlton, Myka Ransom, Laura C Coates, Howard Collier, Claire Davies, Emma Dures, Philip Helliwell, Jana James, Anya Lissina, Vishnu B Madhok, Alison L Nightingale, Jonathan Packham, Catherine Smith, Eldon Spackman, Cerys Tassinari, William Tillett, Sarah T Brown

“…BN models may be a useful method to identify clusters of symptoms that predict PsA with reasonable accuracy. …”
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Political Order and Nomadic Life in Iran: From the Afsharid Period to the End of the Qajar Dynasty by Shahram Gholami, Siavash Gholipour

“…Additionally, nomadic practices often misaligned with the optimal productivity of water and soil resources. …”
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The Ecosystem Services Assessment of Wetlands based on the Classification of Hydrological-ecological Structures and Functions (Case study: Shadegan Wetland) by leila Rahimi, Bahram Malekmohammadi, Ahmad reza Yavari

“…Selecting Shadegan International Wetland as a case study in this research, the ecosystem services approach have been applied to ecological conditions assessment of the wetland based on biophysical structures, processes, functions and ecosystem services in a hydrological-ecological framework, which provides a valuable tool for optimal allocation of wetland resources and their effective management, as well as adopting rational and sustainable policies. 2-Materials and Methods The proposed framework can be considered as a hierarchical approach based on the characteristics of biophysical structure, functions and ecosystem services. …”
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The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation by Guoli Huai, Yong Wang, Jiaxiang Du, Zhenhui Cheng, Yuxuan Xie, Jia Zhou, Hongmei Tang, Yanyan Jiang, Xiangyang Xing, Shaoping Deng, Dengke Pan, Dengke Pan, Dengke Pan

“…IntroductionGenetically edited pigs, modified using CRISPR-Cas9 technology, hold promise as potential sources for xenotransplantation. However, the optimal combination of genetic modifications and their expression levels for initial clinical trials remains unclear. …”
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A Feasibility Study for Clinical Implementation of hypo fractionated SBRT Program at a Clinic in an LMIC Using Locally Designed Lung Phantom by Abigail N.M. Quaye, MPhil, Eric C.D.K. Addison, PhD, Ernest Osei, PhD, Afua A. Yorke, PhD

“…The goal is to alleviate the burden on patients and health care providers, particularly in the context of limited resources. Methods and Materials: A lung phantom was designed from locally sourced materials consisting of wood slabs to mimic the lung, a perspex tank filled with water for tissue equivalence, and a 3-cm diameter acrylic ball to simulate the tumor. …”
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Effects of taurine on growth performance, body composition and physiological responses of western white shrimp, Litopenaeus vannamei broodstock by Vahid Morshedi, Mahmoud Nafisi Bahabadi, Mansour Torfi Mozanzadeh, Amin Oujifard, Naser Agh, Khalegh Maneii, Ahmad Qasemi, Nehzat Bakhshi, Hadi Ebrahimi, Rezvan Tamadoni, Shirin Hamedi, Reza Bagherpour, Fatemeh Solimani

“…In aquaculture, the balance of nutrients in the diet of aquatic animals guarantees optimal growth and health improvement. Taurine (Tau = 2-aminoethanesulfonic acid) is an amino sulfonic acid, which has been proven to be conditionally essential for some aquatic animals when these animals are fed with diets containing high plant protein levels, due to taurine deficiency in plant-based protein sources. …”
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Pregnancy outcomes following surgical repair of female genital fistula in UgandaAJOG Global Reports at a Glance by Abner P. Korn, MD, Justus K. Barageine, PhD, Hadija Nalubwama, MPH, Jaffer Okiring, PhD, Florence Nalubega, MMed, Shane Ian Asiimwe, MMed, Alphonsus Matovu, MMed, Alison M. El Ayadi, ScD

“…We compared outcomes to two external data sources: a meta-analysis and propensity-score matched Ugandan women of reproductive-age. …”
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Advances in Minimally Invasive Treatments for Prostate Cancer: A review of the Role of Ultrasound Therapy and Laser therapy by Corneliu-Dan Blendea, Mohammad Tazim Khan, Marius Stoian, Teodor Claudiu Ion Gligore, Ștefan Cuculici, Ion Lucian Stanciu, Mirela Gabriela-Irina Protosevici, Marius Iordache, Anca Buliman, Carmen Costea-Firan, Ioana Simona Cazacu, Liviu-Constantin Iordache, Doroteea Teoibaș-Șerban

“…While promising for both primary and salvage settings, ongoing research and technological refinements are crucial to optimize their efficacy and expand their clinical utility. …”
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Toward a Domain-Overarching Metadata Schema for Making Health Research Studies FAIR (Findable, Accessible, Interoperable, and Reusable): Development of the NFDI4Health Metadata Sch... by Haitham Abaza, Aliaksandra Shutsko, Sophie A I Klopfenstein, Carina N Vorisek, Carsten Oliver Schmidt, Claudia Brünings-Kuppe, Vera Clemens, Johannes Darms, Sabine Hanß, Timm Intemann, Franziska Jannasch, Elisa Kasbohm, Birte Lindstädt, Matthias Löbe, Katharina Nimptsch, Ute Nöthlings, Marisabel Gonzalez Ocanto, Tracy Bonsu Osei, Ines Perrar, Manuela Peters, Tobias Pischon, Ulrich Sax, Matthias B Schulze, Florian Schwarz, Carolina Schwedhelm, Sylvia Thun, Dagmar Waltemath, Hannes Wünsche, Atinkut A Zeleke, Wolfgang Müller, Martin Golebiewski

“…The National Research Data Infrastructure for Personal Health Data (NFDI4Health) seeks to optimize data sharing among the clinical, epidemiological, and public health research communities while preserving privacy and ethical regulations. …”
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Genetic Diversity and Relationship Analysis of Different Local and International Cultivars and some Strawberry Clones (Fragaria× ananassa Duch) by Masume Abedi, Mehdi Hadadinejad, Kamran Ghasemi, Ghafar Kiani

“…Transplants of imported cultivars were sourced from the Kurdistan Agricultural and Natural Resources Research Center. …”
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CONSORT 2025声明：随机试验报告指南更新版 CONSORT 2025 Statement: Updated Guideline for Reporting Randomised Trials by 译者：李辉1，2，谢雪微1，3 (Translator: LI Hui1,2, XIE Xuewei1,3 )

“…However, there is overwhelming evidence that the quality of reporting is not optimal. The CONSORT statement was designed to improve the quality of reporting and provides a minimum set of items to be included in a report of a randomised trial. …”
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Regulatory effects of laser irradiation on greenhouse-grown strawberry productivity by LEI Kangqi, YANG Han, CHENG Feng, LEI Yumeng, LI Jianwei, QI Yetong, LI Zhitao, QI Xingjiang

“…Supplementing with artificial light sources like Light Emitting Diode (LED) is an effective strategy to address low-light conditions. …”
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Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

“…Sustainability fosters innovation, requiring changes in traditional production and consumption methods. Successful cities have demonstrated how technology aids sustainability. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Collect NHS costs involved in delivering the new pathway and compare with cost of standard pathway calculated from NHS and other sources. Objectives 1 and 2: development of statistical models and diagnostic accuracy Methods Men presenting to their GP with LUTS were recruited prospectively from GP practices in Bristol, Newcastle upon Tyne and Wales. …”
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