High-throughput screening of monoclonal antibodies against carbapenemases using a multiplex protein microarray platform by Sascha D. Braun, Sascha D. Braun, Martin Reinicke, Martin Reinicke, Celia Diezel, Celia Diezel, Elke Müller, Elke Müller, Katrin Frankenfeld, Thomas Schumacher, Hugo Arends, Stefan Monecke, Stefan Monecke, Ralf Ehricht, Ralf Ehricht, Ralf Ehricht

“…However, the development of such assays is often hindered by the time-consuming process of identifying high-affinity antibody pairs.MethodsTo accelerate this process, we evaluated a protein microarray platform as a high-throughput screening tool to identify optimal monoclonal antibody (mAb) pairs targeting the most clinically relevant carbapenemases. …”
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The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation by Guoli Huai, Yong Wang, Jiaxiang Du, Zhenhui Cheng, Yuxuan Xie, Jia Zhou, Hongmei Tang, Yanyan Jiang, Xiangyang Xing, Shaoping Deng, Dengke Pan, Dengke Pan, Dengke Pan

“…IntroductionGenetically edited pigs, modified using CRISPR-Cas9 technology, hold promise as potential sources for xenotransplantation. However, the optimal combination of genetic modifications and their expression levels for initial clinical trials remains unclear. …”
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A Feasibility Study for Clinical Implementation of hypo fractionated SBRT Program at a Clinic in an LMIC Using Locally Designed Lung Phantom by Abigail N.M. Quaye, MPhil, Eric C.D.K. Addison, PhD, Ernest Osei, PhD, Afua A. Yorke, PhD

“…The goal is to alleviate the burden on patients and health care providers, particularly in the context of limited resources. Methods and Materials: A lung phantom was designed from locally sourced materials consisting of wood slabs to mimic the lung, a perspex tank filled with water for tissue equivalence, and a 3-cm diameter acrylic ball to simulate the tumor. …”
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Effects of taurine on growth performance, body composition and physiological responses of western white shrimp, Litopenaeus vannamei broodstock by Vahid Morshedi, Mahmoud Nafisi Bahabadi, Mansour Torfi Mozanzadeh, Amin Oujifard, Naser Agh, Khalegh Maneii, Ahmad Qasemi, Nehzat Bakhshi, Hadi Ebrahimi, Rezvan Tamadoni, Shirin Hamedi, Reza Bagherpour, Fatemeh Solimani

“…In aquaculture, the balance of nutrients in the diet of aquatic animals guarantees optimal growth and health improvement. Taurine (Tau = 2-aminoethanesulfonic acid) is an amino sulfonic acid, which has been proven to be conditionally essential for some aquatic animals when these animals are fed with diets containing high plant protein levels, due to taurine deficiency in plant-based protein sources. …”
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Pregnancy outcomes following surgical repair of female genital fistula in UgandaAJOG Global Reports at a Glance by Abner P. Korn, MD, Justus K. Barageine, PhD, Hadija Nalubwama, MPH, Jaffer Okiring, PhD, Florence Nalubega, MMed, Shane Ian Asiimwe, MMed, Alphonsus Matovu, MMed, Alison M. El Ayadi, ScD

“…We compared outcomes to two external data sources: a meta-analysis and propensity-score matched Ugandan women of reproductive-age. …”
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Advances in Minimally Invasive Treatments for Prostate Cancer: A review of the Role of Ultrasound Therapy and Laser therapy by Corneliu-Dan Blendea, Mohammad Tazim Khan, Marius Stoian, Teodor Claudiu Ion Gligore, Ștefan Cuculici, Ion Lucian Stanciu, Mirela Gabriela-Irina Protosevici, Marius Iordache, Anca Buliman, Carmen Costea-Firan, Ioana Simona Cazacu, Liviu-Constantin Iordache, Doroteea Teoibaș-Șerban

“…Findings from 29 peer-reviewed articles were extracted, focusing on treatment efficacy, safety profiles, and comparative analyses against conventional methods. In addition to the 29 studies identified through the systematic PubMed search, supplementary references were incorporated to provide essential contextual background, support methodological frameworks, and enrich the discussion of emerging technologies and clinical implications. …”
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Establishment of jujube anther culture and plant regeneration system by GUO Kaiwen, XU Chongchong, HU Yaning, HUANG Jian

“…In this study, three jujube varieties, Dongzao, Junzao and Qiyuexian, were used as materials. By optimizing the ratios of plant growth regulators, carbon sources, and cultivation conditions, an efficient anther culture regeneration system was established. …”
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Toward a Domain-Overarching Metadata Schema for Making Health Research Studies FAIR (Findable, Accessible, Interoperable, and Reusable): Development of the NFDI4Health Metadata Sch... by Haitham Abaza, Aliaksandra Shutsko, Sophie A I Klopfenstein, Carina N Vorisek, Carsten Oliver Schmidt, Claudia Brünings-Kuppe, Vera Clemens, Johannes Darms, Sabine Hanß, Timm Intemann, Franziska Jannasch, Elisa Kasbohm, Birte Lindstädt, Matthias Löbe, Katharina Nimptsch, Ute Nöthlings, Marisabel Gonzalez Ocanto, Tracy Bonsu Osei, Ines Perrar, Manuela Peters, Tobias Pischon, Ulrich Sax, Matthias B Schulze, Florian Schwarz, Carolina Schwedhelm, Sylvia Thun, Dagmar Waltemath, Hannes Wünsche, Atinkut A Zeleke, Wolfgang Müller, Martin Golebiewski

“…This study describes the development, structure, and implementation of this MDS designed to improve the FAIRness of metadata from clinical, epidemiological, and public health research while maintaining compatibility with metadata models of other resources to ease interoperability. MethodsBased on the models of DataCite, ClinicalTrials.gov, and other data models and international standards, the first MDS version was developed by the NFDI4Health Task Force COVID-19. …”
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Emission Characteristics of Concrete Mixer Trucks Under Real-world Operating Conditions by Xinbo SHI, Yao CHEN, Jin LI, Peixuan LI, Zihang ZHOU, Bin WANG, Xue CHEN

“…Therefore, conducting emission studies based on real-world conditions is essential for analyzing emission variations under different operating scenarios and for effectively controlling emissions from mobile sources.Methods This study selected concrete mixer trucks with high activity levels and representative operating areas in Chengdu to investigate the real emission characteristics of these vehicles during actual task processes. …”
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Genetic Diversity and Relationship Analysis of Different Local and International Cultivars and some Strawberry Clones (Fragaria× ananassa Duch) by Masume Abedi, Mehdi Hadadinejad, Kamran Ghasemi, Ghafar Kiani

“…Consequently, this study was conducted to investigate genetic diversity and identify relationships between domestic and imported strawberry genotypes and clones. Methods: The present study was carried out in Mazandaran Province, Sari City, from November 2020 to June 2021. …”
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CONSORT 2025声明：随机试验报告指南更新版 CONSORT 2025 Statement: Updated Guideline for Reporting Randomised Trials by 译者：李辉1，2，谢雪微1，3 (Translator: LI Hui1,2, XIE Xuewei1,3 )

“…Here, we present the updated CONSORT 2025 statement, which aims to account for recent methodological advancements and feedback from end users. Methods We conducted a scoping review of the literature and developed a project-specific database of empirical and theoretical evidence related to CONSORT to generate a list of potential changes to the checklist. …”
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Early detection to improve outcome in people with undiagnosed psoriatic arthritis: the PROMPT research programme including RCT by Neil McHugh, Laura Bojke, Mel Brooke Turfrey, Rachel Charlton, Myka Ransom, Laura C Coates, Howard Collier, Claire Davies, Emma Dures, Philip Helliwell, Jana James, Anya Lissina, Vishnu B Madhok, Alison L Nightingale, Jonathan Packham, Catherine Smith, Eldon Spackman, Cerys Tassinari, William Tillett, Sarah T Brown

“…BN models may be a useful method to identify clusters of symptoms that predict PsA with reasonable accuracy. …”
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Explaining the Comprehensive Human-To-Human Marketig System in the Health Tourism Industry by Ali Pourang, Meysam Shirkhodaie, Mahmood Yahyazadeh far, Mohsen Alizadeh San, Masoomeh Tavangar

“…Sampling was carried out theoretically using the snowball method, and the sample size was determined based on theoretical saturation logic. …”
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Political Order and Nomadic Life in Iran: From the Afsharid Period to the End of the Qajar Dynasty by Shahram Gholami, Siavash Gholipour

“…The central question guiding this inquiry was: What impact did the political system have on the nomadic way of life? Materials & Methods This research employed a descriptive-analytical approach, focusing on the period from the rise of the Afsharid dynasty to the end of the Qajar dynasty. …”
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Regulatory effects of laser irradiation on greenhouse-grown strawberry productivity by LEI Kangqi, YANG Han, CHENG Feng, LEI Yumeng, LI Jianwei, QI Yetong, LI Zhitao, QI Xingjiang

“…Supplementing with artificial light sources like Light Emitting Diode (LED) is an effective strategy to address low-light conditions. …”
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Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

“…Sustainability fosters innovation, requiring changes in traditional production and consumption methods. Successful cities have demonstrated how technology aids sustainability. …”
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Search for Neutrino Doublets and Triplets Using 11.4 yr of IceCube Data by R. Abbasi, M. Ackermann, J. Adams, S. K. Agarwalla, J. A. Aguilar, M. Ahlers, J.M. Alameddine, N. M. Amin, K. Andeen, C. Argüelles, Y. Ashida, S. Athanasiadou, S. N. Axani, R. Babu, X. Bai, A. Balagopal V., M. Baricevic, S. W. Barwick, S. Bash, V. Basu, R. Bay, J. J. Beatty, J. Becker Tjus, J. Beise, C. Bellenghi, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, E. Blaufuss, L. Bloom, S. Blot, F. Bontempo, J. Y. Book Motzkin, C. Boscolo Meneguolo, S. Böser, O. Botner, J. Böttcher, J. Braun, B. Brinson, Z. Brisson-Tsavoussis, J. Brostean-Kaiser, L. Brusa, R. T. Burley, D. Butterfield, M. A. Campana, I. Caracas, K. Carloni, J. Carpio, S. Chattopadhyay, N. Chau, Z. Chen, D. Chirkin, S. Choi, B. A. Clark, A. Coleman, P. Coleman, G. H. Collin, A. Connolly, J. M. Conrad, R. Corley, D. F. Cowen, C. De Clercq, J. J. DeLaunay, D. Delgado, S. Deng, A. Desai, P. Desiati, K. D. de Vries, G. de Wasseige, T. DeYoung, A. Diaz, J. C. Díaz-Vélez, P. Dierichs, M. Dittmer, A. Domi, L. Draper, H. Dujmovic, D. Durnford, K. Dutta, M. A. DuVernois, T. Ehrhardt, L. Eidenschink, A. Eimer, P. Eller, E. Ellinger, S. El Mentawi, D. Elsässer, R. Engel, H. Erpenbeck, W. Esmail, J. Evans, P. A. Evenson, K. L. Fan, K. Fang, K. Farrag, A. R. Fazely, A. Fedynitch, N. Feigl, S. Fiedlschuster, C. Finley, L. Fischer, D. Fox, A. Franckowiak, S. Fukami, P. Fürst, J. Gallagher, E. Ganster, A. Garcia, M. Garcia, G. Garg, E. Genton, L. Gerhardt, A. Ghadimi, C. Girard-Carillo, C. Glaser, T. Glüsenkamp, J. G. Gonzalez, S. Goswami, A. Granados, D. Grant, S. J. Gray, S. Griffin, S. Griswold, K. M. Groth, D. Guevel, C. Günther, P. Gutjahr, C. Ha, C. Haack, A. Hallgren, L. Halve, F. Halzen, L. Hamacher, H. Hamdaoui, M. Ha Minh, M. Handt, K. Hanson, J. Hardin, A. A. Harnisch, P. Hatch, A. Haungs, J. Häussler, K. Helbing, J. Hellrung, J. Hermannsgabner, L. Heuermann, N. Heyer, S. Hickford, A. Hidvegi, C. Hill, G. C. Hill, R. Hmaid, K. D. Hoffman, S. Hori, K. Hoshina, M. Hostert, W. Hou, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, K. Hymon, A. Ishihara, W. Iwakiri, M. Jacquart, S. Jain, O. Janik, M. Jansson, M. Jeong, M. Jin, B. J. P. Jones, N. Kamp, D. Kang, W. Kang, X. Kang, A. Kappes, D. Kappesser, L. Kardum, T. Karg, M. Karl, A. Karle, A. Katil, U. Katz, M. Kauer, J. L. Kelley, M. Khanal, A. Khatee Zathul, A. Kheirandish, J. Kiryluk, S. R. Klein, Y. Kobayashi, A. Kochocki, R. Koirala, H. Kolanoski, T. Kontrimas, L. Köpke, C. Kopper, D. J. Koskinen, P. Koundal, M. Kowalski, T. Kozynets, N. Krieger, J. Krishnamoorthi, T. Krishnan, K. Kruiswijk, E. Krupczak, A. Kumar, E. Kun, N. Kurahashi, N. Lad, C. Lagunas Gualda, M. Lamoureux, M. J. Larson, F. Lauber, J. P. Lazar, K. Leonard DeHolton, A. Leszczyńska, J. Liao, M. Lincetto, Y. T. Liu, M. Liubarska, C. Love, L. Lu, F. Lucarelli, W. Luszczak, Y. Lyu, J. Madsen, E. Magnus, K. B. M. Mahn, Y. Makino, E. Manao, S. Mancina, A. Mand, W. Marie Sainte, I. C. Mariş, S. Marka, Z. Marka, M. Marsee, I. Martinez-Soler, R. Maruyama, F. Mayhew, F. McNally, J. V. Mead, K. Meagher, S. Mechbal, A. Medina, M. Meier, Y. Merckx, L. Merten, J. Mitchell, T. Montaruli, R. W. Moore, Y. Morii, R. Morse, M. Moulai, T. Mukherjee, R. Naab, M. Nakos, U. Naumann, J. Necker, A. Negi, L. Neste, M. Neumann, H. Niederhausen, M. U. Nisa, K. Noda, A. Noell, A. Novikov, A. Obertacke Pollmann, V. O’Dell, A. Olivas, R. Orsoe, J. Osborn, E. O’Sullivan, V. Palusova, H. Pandya, N. Park, G. K. Parker, V. Parrish, E. N. Paudel, L. Paul, C. Pérez de los Heros, T. Pernice, J. Peterson, A. Pizzuto, M. Plum, A. Pontén, Y. Popovych, M. Prado Rodriguez, B. Pries, R. Procter-Murphy, G. T. Przybylski, L. Pyras, C. Raab, J. Rack-Helleis, N. Rad, M. Ravn, K. Rawlins, Z. Rechav, A. Rehman, E. Resconi, S. Reusch, W. Rhode, B. Riedel, A. Rifaie, E. J. Roberts, S. Robertson, S. Rodan, M. Rongen, A. Rosted, C. Rott, T. Ruhe, L. Ruohan, D. Ryckbosch, I. Safa, J. Saffer, D. Salazar-Gallegos, P. Sampathkumar, A. Sandrock, M. Santander, S. Sarkar, S. Sarkar, J. Savelberg, P. Savina, P. Schaile, M. Schaufel, H. Schieler, S. Schindler, L. Schlickmann, B. Schlüter, F. Schlüter, N. Schmeisser, T. Schmidt, J. Schneider, F. G. Schröder, L. Schumacher, S. Schwirn, S. Sclafani, D. Seckel, L. Seen, M. Seikh, M. Seo, S. Seunarine, P. Sevle Myhr, R. Shah, S. Shefali, N. Shimizu, M. Silva, B. Skrzypek, B. Smithers, R. Snihur, J. Soedingrekso, A. Søgaard, D. Soldin, P. Soldin, G. Sommani, C. Spannfellner, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, T. Stezelberger, T. Stürwald, T. Stuttard, G. W. Sullivan, I. Taboada, S. Ter-Antonyan, A. Terliuk, M. Thiesmeyer, W. G. Thompson, J. Thwaites, S. Tilav, K. Tollefson, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, M. A. Unland Elorrieta, A. K. Upadhyay, K. Upshaw, A. Vaidyanathan, N. Valtonen-Mattila, J. Vandenbroucke, N. van Eijndhoven, D. Vannerom, J. van Santen, J. Vara, F. Varsi, J. Veitch-Michaelis, M. Venugopal, M. Vereecken, S. Vergara Carrasco, S. Verpoest, D. Veske, A. Vijai, C. Walck, A. Wang, C. Weaver, P. Weigel, A. Weindl, J. Weldert, A. Y. Wen, C. Wendt, J. Werthebach, M. Weyrauch, N. Whitehorn, C. H. Wiebusch, D. R. Williams, L. Witthaus, M. Wolf, G. Wrede, X. W. Xu, J. P. Yanez, E. Yildizci, S. Yoshida, R. Young, F. Yu, S. Yu, T. Yuan, A. Zegarelli, S. Zhang, Z. Zhang, P. Zhelnin, P. Zilberman, M. Zimmerman, IceCube Collaboration

“…We report a search for high-energy astrophysical neutrino multiplets, detections of multiple neutrino clusters in the same direction within 30 days, based on an analysis of 11.4 yr of IceCube data. A new search method optimized for transient neutrino emission with a monthly timescale is employed, providing a higher sensitivity to neutrino fluxes. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Collect NHS costs involved in delivering the new pathway and compare with cost of standard pathway calculated from NHS and other sources. Objectives 1 and 2: development of statistical models and diagnostic accuracy Methods Men presenting to their GP with LUTS were recruited prospectively from GP practices in Bristol, Newcastle upon Tyne and Wales. …”
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A systematic review of reinforcement learning-based control for microgrids: trends, challenges, and emerging algorithms by A. V. Waghmare, V. P. Singh, T. Varshney, P. Sanjeevikumar

“…Summary and critical assessment of main findings and contributions in this field are tabulated through methodical categorization of selected articles. Emerging algorithms for microgrid control are also discussed thoroughly. …”
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Study on the evolution mechanism of adiabatic shear bands during the deformation of medium carbon bainitic steel acted upon by high strain rates by Songbo Zhou, Feng Hu, Rui Ke, Hua Zheng, Yingying Wang, Houkui Xiang, Kaiming Wu

“…The microstructure evolution and formation mechanism of adiabatic shear bands of bainitic steel during high strain rate deformation are methodically examined via a split Hopkinson pressure bar. …”
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