Fractal Characteristics of Pore Structure of Longmaxi Shales with Different Burial Depths in Southern Sichuan and Its Geological Significance by Manping Yang, Yanyan Pan, Hongye Feng, Qiang Yan, Yanjun Lu, Wanxin Wang, Yu Qi, Hongjian Zhu

“…Burial depth can significantly impact the pore structure characteristics of shale. …”
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Deciphering the mechanisms of long non-coding RNAs in ferroptosis: insights into its clinical significance in cancer progression and immunology by Shengming Ou, Xiaoya Nie, Xiangyu Qiu, Xin Jin, Geyan Wu, Rongxin Zhang, Jinrong Zhu

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Recent advances in the regulatory and non-coding RNA biology of osteogenic differentiation: biological functions and significance for bone healing by Samaris Aranguren, Hisae Cole, Lauren Jeannette Dargan, Madison Sarlo, Sumin Choi, Isha Satapathy, Jaira Ferreira de Vasconcellos

“…We focused on circular RNAs, small nucleolar RNAs and PIWI-interacting RNAs and comprehensively summarized their biological functions as well as discussed their significance for bone healing and tissue regeneration.…”
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Improving Growth and Productivity of Oleiferous Brassicas under Changing Environment: Significance of Nitrogen and Sulphur Nutrition, and Underlying Mechanisms by Naser A. Anjum, Sarvajeet S. Gill, Shahid Umar, Iqbal Ahmad, Armando C. Duarte, Eduarda Pereira

“…The current paper updates readers on the significance of N and S for the improvement of plant growth, development, and productivity in detail. …”
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Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation. by Kevin N Couper, Tom Barnes, Julius C R Hafalla, Valery Combes, Bernhard Ryffel, Thomas Secher, Georges E Grau, Eleanor M Riley, J Brian de Souza

“…In vitro, these MPs induced significantly higher levels of macrophage activation than intact infected red blood cells. …”
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Comprehensive Analysis of microRNA Methylation Profiles and Determination of Their Functional Significance in Colorectal Cancer: A Study Protocol by Nurul Syakima Ab Mutalib, Imilia Ismail, Muhammad Redha Abdullah Zawawi, Nadiah Abu, Siti Aishah Sulaiman, Loh Teng-Hern Tan, Learn-Han Lee

“…In CRC, microRNAs, a type of short non-coding RNA, are found to be deregulated and can significantly influence its onset and progression. However, previous microRNA research primarily focused on expression levels to ascertain their biological significance, leaving the microRNA methylation landscapes in CRC patients largely unexplored. …”
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The Alteration and Clinical Significance of Th22/Th17/Th1 Cells in Patients with Chronic Myeloid Leukemia by Ping Chen, Min Wang, Daqi Li, Yan Jia, Na He, Wei Li, Daoxin Ma, Chunyan Ji

“…In addition, there existed a significantly positive relationship between Th22 and Th17 cells in PB or BM. …”
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Noninvasive diagnosis model for predicting significant liver inflammation in patients with chronic hepatitis B in the immune-tolerant phase by Shanshan Chen, Lu Huang, Yili Chu, Jiangshan Lian, Hui Shao, Tingting Wang, Xuehan Zou, Haijun Huang

“…The nomogram can accurately identify significant liver inflammation in immune-tolerant phase CHB patients and facilitate the early initiation of antiviral therapy, thereby reducing the need for clinical liver biopsies.…”
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People with symptoms of depression and those at significant risk of suicide show differences in their personality profile and sense of meaning in life by Kacper Deska, Grzegorz Mirocha, Bartłomiej Bąk, Anna Mirgos-Wierzchowska, Marcin Kosmalski, Monika Różycka-Kosmalska, Tadeusz Pietras

“…Additionally, 80 participants (28.9%) were assessed to be at significant risk of suicide according to the SBQ-R scale. …”
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Do our students learn to treat patients? A necessary approach due to the social significance of a problem by Luis Alberto Corona Martínez

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Clinical significance of serum cystatin C‐to‐creatinine ratio as a surrogate marker for incident osteoporotic fracture predictions by Ichiro Yoshii, Naoya Sawada, Tatsumi Chijiwa

“…We statistically evaluated the significance of serum cystatin C‐to‐creatinine ratio (CysC/Cr) as a surrogate marker for incident major osteoporotic fractures (MOF) prediction. …”
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Author Correction: Secondhand smoking increased the possibility of hypertension with a significant time and frequency dose-response relationship by Suixia Cao, Jingchun Liu, Yating Huo, Huimeng Liu, Yutong Wang, Binyan Zhang, Kun Xu, Peiying Yang, Lingxia Zeng, Shaonong Dang, Hong Yan, Baibing Mi

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Pulsed Electric Field Induces Significant Changes in the Metabolome of <i>Fusarium</i> Species and Decreases Their Viability and Toxigenicity by Adam Behner, Jana Palicova, Anna-Hirt Tobolkova, Nela Prusova, Milena Stranska

“…As we found out, both fungal viability and the ability to produce mycotoxins significantly decreased after the PEF treatment for all of the species tested. …”
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The significance of matrix remodeling associated 7 (MXRA7) in pathogenesis or management of renal diseases deserves more investigations by Yiqiang Wang

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Prognostic significance of the logistic regression model for assessing the risk of recurrence in patients with prostate cancer after radical prostatectomy by S. A. Reva, A. V. Arnautov, O. A. Klitsenko, S. B. Petrov

“…The study’s objective is to investigate the influence of risk factors for recurrence of prostate cancer (PCa) after radical surgical treatment on the unfavourable course of recurrence of the disease with the formation of a set of the most significant factors of a model that reflects the likelihood of relapse.Materials and methods. …”
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The significance of Jesus' utterance in relation to the Johannine Son of Man: a speech act analysis of John 9:35 by H. Ito

“…In order to accomplish that, this article will examine the significance of Jesus’ utterance in John 9:35, which contains some difficulty in interpreting the meaning of the title Son of Man. …”
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Composition and Distribution Characteristics and Geochemical Significance of n-Alkanes in Core Sediments in the Northern Part of the South Yellow Sea by Jinxian He, Shengyin Zhang, Xiaoli Zhang, Yu Qian, Haijun He, Hongchen Wu

“…The South Yellow Sea is an important carbon sink and a significant research area of carbon cycle. After studying the composition and distribution of n-alkanes in a 250 cm long sediment core in the northern part of South Yellow Sea, it can be found that all n-alkanes of sediment samples in this research are distributed in three types, that is, double peak groups, predominance of long-chain n-alkanes, and predominance of short-chain n-alkanes. …”
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Il-6 and MSH3 in colorectal carcinoma: Expression, relationship, and prognostic significance in 171 colorectal carcinoma cases by Elif Kolay Bayram, Betul Ogut, Mehmet Arda Inan, Ayse Dursun

“…MSH3 staining was significantly reduced in the patient group with high TILs (P = 0.035). …”
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Gamma-Glutamyl Transpeptidase-to-Platelet Ratio Predicts Significant Liver Fibrosis of Chronic Hepatitis B Patients in China by Tianyi Ren, Huan Wang, Ruihong Wu, Junqi Niu

“…The area under the receiver operating characteristic curves (AUROC) of GPR for fibrosis (0.77 versus 0.70, P=0.03), significant fibrosis (0.70 versus 0.63, P=0.02), and extensive fibrosis (0.71 versus 0.64, P=0.02) were significantly higher than those of APRI. …”
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Analysis of significantly associated regions and candidate genes for dwarf stem trait in Brassica napus based on BSA-sequencing by ZHAO Weiguo, TA Na, WANG Hao, YANG Zelin

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