The role of partial splenic artery embolization in the management of refractory esophageal variceal bleeding due to portal vein thrombosis by Büşra Tetik Dinçer, Nafiye Urgancı, Aylin Hasanefendioğlu Bayrak, Özlem Durmaz, İlgin Özden

“…Medical treatment with a proton pump inhibitor and beta-blocker was initiated. The patient underwent endoscopic band ligation (EBL) three times over 9 months. …”
Get full text

Co-creating a person-centered creative engagement intervention for Parkinson's care by Blanca T. M. Spee, Blanca T. M. Spee, Blanca T. M. Spee, Thieme B. Stap, Thieme B. Stap, Marjoke Plijnaer, Gert Pasman, Sara Zeggio, Annelien Duits, Annelien Duits, Julia S. Crone, Suzanne Haeyen, Suzanne Haeyen, Matthew Pelowski, Matthew Pelowski, Bastiaan R. Bloem, Jan-Jurjen Koksma

“…., duration of the intervention and sessions), (ii) freedom in selection of creative media, (iii) environment as a creative playground, (iv) skills of creative therapists, (v) PD-specific considerations, (vi) financial considerations and logistics, and we list (vii) responsibilities of the Design Team.DiscussionThis study establishes an initial framework for a PD-specific creative arts therapy intervention designed as a creative engagement learning environment. …”
Get full text

Nutritional and General Awareness of Vitamin D Status among Adult Population in Sulaymaniyah Governorate, Kurdistan Region, Iraq: A Cross-Sectional Study by Reder Rafiq Mohammed Salih, Fadhluddin Nasruddin Shakor, Dalia Ardal Ali, Rafiq Mohammed Salih Rashid

“…Implementing nutrition education initiatives, encouraging healthy lifestyles, and supporting vitamin D examination should be included in Iraq's health care system. …”
Get full text

Preparation of Iron Oxide and Titania-Based Composite, Core-Shell Populated, Nanoparticulates Material by Two-Step LASER Ablation in Aqueous Media as Antimicrobial and Anticancer A... by Hasan H. Bahjat, Raid A. Ismail, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Mohsen Al-Omar, Salman A. A. Mohammed, Riaz A. Khan

“…The flow cytometry analyses confirmed the NPs’ cytotoxic impacts against the human lung cancer A549 cell lines through the initiation of apoptosis and promotion of the cell cycle arrest at the G1 phase of cell division. …”
Get full text

Characteristics and outcomes of women using emergency medical services for third-trimester pregnancy-related problems in India: a prospective observational study by Jennifer A Newberry, Corey B Bills, Elizabeth A Pirrotta, Matthew C Strehlow, G V Ramana Rao, Hyeyoun (Elise) Min, Ann E Evensen, Lawrence Leeman, S V Mahadevan

“…Women were primarily from rural or tribal areas (1550/1684 (92.0%)) and lower economic strata (1177/1684 (69.9%)). Time from initial call to hospital arrival was longer for rural/tribal compared with urban patients (66 min (IQR 51–84) vs 56 min (IQR 42–73), respectively, p<0.0001). …”
Get full text

PD-L1 and IFN-γ modulate Non-Small Cell Lung Cancer (NSCLC) cell plasticity associated to immune checkpoint inhibitor (ICI)-mediated hyperprogressive disease (HPD) by Stefania Angelicola, Francesca Giunchi, Francesca Ruzzi, Mariateresa Frascino, Mary Pitzalis, Laura Scalambra, Maria Sofia Semprini, Olga Maria Pittino, Chiara Cappello, Irene Siracusa, Ilaria Candida Chillico, Martina Di Noia, Cristian Turato, Silvia De Siervi, Francesco Lescai, Teresa Ciavattini, Giulia Lopatriello, Luca Bertoli, Hugo De Jonge, Luisa Iamele, Annalisa Altimari, Elisa Gruppioni, Andrea Ardizzoni, Marzia Rossato, Francesco Gelsomino, Pier-Luigi Lollini, Arianna Palladini

“…Two primary cell cultures were established from samples of a NSCLC patient, before ICI initiation (“baseline”, NSCLC-B) and during HPD (“hyperprogression”, NSCLC-H). …”
Get full text

Electrocardiographic signs of cardiac ischemia at rest and during exercise in patients with COPD traveling to 3,100 m: data from a randomized trial of acetazolamide by Marla Christen, Marla Christen, Aline Buergin, Aline Buergin, Maamed Mademilov, Maamed Mademilov, Laura Mayer, Laura Mayer, Simon R. Schneider, Simon R. Schneider, Mona Lichtblau, Mona Lichtblau, Talant M. Sooronbaev, Talant M. Sooronbaev, Silvia Ulrich, Silvia Ulrich, Konrad E. Bloch, Konrad E. Bloch, Michael Furian, Michael Furian

“…We assessed electrocardiogram (ECG)-derived signs of cardiac ischemia and the effects of preventive acetazolamide therapy in COPD patients traveling to high altitudes.MethodsPatients with COPD [Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) grades 2–3] and a predicted forced expiratory volume in 1 s (FEV1) of 66 ± 11% (mean ± SD), aged 57 ± 8 years, and living <1,000 m were included in this analysis of secondary outcomes from a randomized placebo-controlled double-blind trial (www.clinicaltrials.gov, NCT03156231). …”
Get full text

Mechanism of Tai Chi Chuan in Improving Knee Osteoarthritis from the Perspective of Sports Biomechanics by LIU Longcheng, ZHANG Feng, GAO Pengyi, ZHAO Tianlin, WANG Honghao, LI LIU Yinuo, WANG Jiaying, ZHU Xiangyu

“…The changes in biomechanical parameters are the initial factors and pathological basis of KOA. This study explores the mechanical effects of Tai Chi Chuan on the knee joint of patients with KOA based on sports biomechanics and analyzes the potential mechanism of Tai Chi Chuan in improving KOA, in order to provide a theoretical basis for Tai Chi Chuan intervention in KOA. …”
Get full text

Evaluating the World Health Organization’s Hearts Model for Hypertension and Diabetes Management: A Pilot Implementation Study in Guatemala by Irmgardt Alicia Wellmann, Luis Fernando Ayala, Taryn M. Valley, Vilma Irazola, Mark D. Huffman, Michele Heisler, Peter Rohloff, Rocío Donis, Eduardo Palacios, Manuel Ramírez-Zea, David Flood

“…Background: The World Health Organization HEARTS Technical Package is a widely implemented global initiative to improve the primary care management of cardiovascular disease risk factors. …”
Get full text

Developing a business model focused on the planning sustainability of forest sector enterprises by Ihor Soloviy, Orest Kiyko, Vasyl Lavnyy, Igor Bukhanevych, Oksana Pelyukh, Mykhailo Ilkiv, Taras Chelepis, Dmytro Savka, Andriy Lutsenco

“…Similar to the environmental layer of the business model framework, the social layer of the framework extends the initial (economic) business model by examining the organization's interaction with society through the lens of stakeholders. …”
Get full text

High-Fat Mouse Model to Explore the Relationship between Abnormal Lipid Metabolism and Enolase in Pancreatic Cancer by Lin Qin, Kai Sun, Li Shi, Yushan Xu, Rongping Zhang

“…We confirmed that the serum triglyceride level of pancreatic cancer patients at initial diagnosis is overtopping nonpancreatic cancer patients, and the neuron-specific enolase level of patients with pancreatic carcinoma is better than nonpancreatic carcinoma sufferers. …”
Get full text

Treating chronic kidney disease in Danish primary care: results from the observational ATLAS study by Morten Lindhardt, Søren Tang Knudsen, Thomas Saxild, Morten Charles, Rikke Borg

“…Most PCPs identified CKD using eGFR < 60 mL/min/1.73 m2 (62%) or UACR > 30 mg/g (58%) and 62% reported initiating treatment to retard kidney function decline. …”
Get full text

Assessments of prostate cancer cell functions highlight differences between a pan‐PI3K/mTOR inhibitor, gedatolisib, and single‐node inhibitors of the PI3K/AKT/mTOR pathway by Adrish Sen, Salmaan Khan, Stefano Rossetti, Aaron Broege, Ian MacNeil, Ann DeLaForest, Jhomary Molden, Laura Davis, Charles Iversrud, Megan Seibel, Ross Kopher, Stephen Schulz, Lance Laing

“…Loss of the PI3K regulator PTEN is frequent during prostate cancer (PC) initiation, progression, and therapeutic resistance. …”
Get full text

A Rare Case of Mosaic 3pter and 5pter Deletion-Duplication with Autism Spectrum Disorder and Dyskinesia by Luna Bajracharya, Meena Lall, Sunita Bijarnia-Mahay, Praveen Kumar, Imran Mushtaq, Pushpa Saviour, Preeti Paliwal, Anju Joshi, Shruti Agarwal, Praveen Suman

“…Occupational, sensory integration, and behavior modification therapy were initiated for his autistic features, and anticholinergic trihexiphenidyl was prescribed for hyperkinetic movements. …”
Get full text

Mme de Graffigny and the Archduchess: Indirect Correspondence between the Court and 'le monde' by Kelsey Rubin-Detlev

“…By pretending to discuss between themselves Maria Elisabeth’s reputation and that of other ladies, Copineau and Graffigny sought to initiate Maria Elisabeth into eighteenth-century sociability and accordingly to teach the archduchess to manage her vivacious wit, to suppress her habit of criticising others and, in essence, to learn how to behave properly in society. …”
Get full text

The adolescent experience of hereditary angioedema: a qualitative study of disease burden and treatment experience by Lynne Broderick, April Foster, Laura Tesler Waldman, Laura Bordone, Aaron Yarlas

“…Impacts on emotional and social functioning were particularly noteworthy, as participants reported having to miss or skip social events, and sometimes withdrawing socially. Since initiating prophylaxis, participants reported the frequency, severity, and duration of attacks had been reduced and their HAE-related impacts had been minimized. …”
Get full text

Changing of taste organ in Persian sturgeon (Acipenser persicus, Borodin, 1897) during early development by Mohammadamin Zarini, Soheil Eagderi, Bagher Mojazi Amiri, Mahta Arabshahi

“…Introduction: In the first stage of the aquaculture program of a species, it is necessary to know the stages of its initial development. In artificial reproduction programs and after the fertilization stage, an important issue is the feeding of the larvae after the absorption of the yolk sac, because the greatest loss of fish occurs during the absorption of the yolk sac and the stage of transition from endogenous feeding to exogenous feeding. …”
Get full text

The effect of different feed on the spawning performance of mud crab Scylla serrata broodstock by Bethsy J. Pattiasina, Endang Jamal, Agapery Y. Pattinasarany

“…Mud crab of Scylla serrata with initial weight of 500.7±103.4 g, preferably under developed gonads were maintained in a fiber tank measuring length of 2.48 m, width 1.26 m, and a height of 60 cm which is partition sealed into 30×40×60 cm3 to put one crab. …”
Get full text

The prevalence of hand pathology in regional orthopaedic hospitals in KwaZulu-Natal: A cross-sectional study by S Thabit, M O'Connor, W Parker, T Mashishi, K Moodley, A Peer, K Matanzima, A J de Villiers, O Adewusi, R Aboobaker, A Rocher

“…Identifying where the greatest need is can direct patient awareness initiatives, medical training and appropriate allocation of resources. …”
Get full text

Timely access to specialist outpatient care: can applying systems thinking unblock our waiting lists? by Sue McAvoy, Agnes Toth-Peter, Ninad Jagdish, Bao Hoang Nguyen, Allison Arnott, Lisa Nissen

“…Waitlists, which record the number of patients waiting for an initial consultation (new appointment), are an indicator of a health system under strain. …”
Get full text