Impact of alcohol drinking and tobacco smoking on the drug-resistance of newly diagnosed tuberculosis: a retrospective cohort study in Shandong, China, during 2004–2020 by Yi-Fan Li, Yao Liu, Qi Fu, Wan-mei Song, Jin-yue Liu, Qian-yun Zhang, Ting-ting Xu, Shi-jin Li, Qi-qi An, Si-qi Liu, Huai-chen Li, Ning Ning Tao, Xue-han Zhu, Chun-bao Yu, Jihua Dong

“…However, there were no significant differences between G1 and G0, G2 and G0 in all drug-resistant subtypes. …”
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Determinants of 5-year survival in patients with advanced NSCLC with PD-L1≥50% treated with first-line pembrolizumab outside of clinical trials: results from the Pembro-real 5Y glo... by Mieke Van Hemelrijck, Salvatore Grisanti, Avinash Aujayeb, Martin Forster, Giannis Mountzios, Andrea Napolitano, Bruno Vincenzi, Joachim G J V Aerts, Marina Garassino, Valter Torri, Solange Peters, Alex Friedlaender, Alfredo Addeo, Giuseppe Lo Russo, Roberto Ferrara, Diego Signorelli, Alessandro Russo, So Yeon Kim, Jarushka Naidoo, Scott Gettinger, Heather Wakelee, Martin Sebastian, Mark Awad, Abdul Rafeh Naqash, Alessio Cortellini, Raffaele Giusti, Michele De Tursi, Federica Zoratto, Marco Russano, Rita Chiari, Biagio Ricciuti, Andrea De Giglio, Alain Gelibter, Giuseppe Tonini, Amin H Nassar, Alessandra Curioni-Fontecedro, Eleni Karapanagiotou, Emilio Bria, Jack Bell, Paolo Bironzo, Joao V Alessi, Alessandro Morabito, David J Pinato, Francesco Passiglia, Carlo Genova, Francesca Mazzoni, Alessandro Inno, Francesco Grossi, Luca Cantini, Lorenza Landi, Luigi Della Gravara, Margarita Majem, Uma Mukherjee, Federica Biello, Alessandro Leonetti, Annalisa Guida, Marianna Macerelli, Gabriele Minuti, Giulio Metro, Thomas Newsom-Davis, Eleni Josephides, Andrea Camerini, Elisa Roca, David O’Reilly, Mingjia Li, Laura Mezquita, Teresa Gorría, Claudia A M Fulgenzi, Lauren Young, Joel W Neal, Javier Baena, Francesco Pantano, Jacobo Rogado, Mary Jo Fidler, Teresa Beninato, Federica Pecci, Alessandro Di Federico, Kazuki Takada, Leonardo Brunetti, Talal El Zarif, Laura Moliner, Alberto Servetto, Sukumar Kalvapudi, Sai Yendamuri, Edoardo Garbo, Giuseppina Rita Di Fazio, Monica Loza, Ritujith Jayakrishnan, Michele Montrone, Nichola O Awosika, Bartlomiej Tomasik, Maximilian Rost, Isabelle Monnet, Francesco Agustoni, Artur Katz, Dwight Hall Owen, Michele Ghidini, Armida D’Incecco, Gianpaolo Spinelli, Monica Verrico, Manuel Dupont, Rafael Di Marco Barros, Diego Luigi Cortinovis, Chiara Bennati, Frank Aboubakar Nana, Anne-Marie Dingemans, Taher Abu Hejleh

“…Neither the overall study population nor the KN024 look-alike cohort exhibited significantly different OS compared with the KN024 IPD cohort. …”
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Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade by Shaoyong Peng, Minshan Wu, Qian Yan, Gaopo Xu, Yumo Xie, Guannan Tang, Jinxin Lin, Zixu Yuan, Xiaoxia Liang, Ze Yuan, Jingrong Weng, Liangliang Bai, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo, Xiaoxia Liu

“…Cancer‐associatedfibroblasts (CAFs) are significant in immune escape and resistance toimmunotherapy, emphasizing the urgent need for new treatment strategies. …”
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Characterisation of pregnancy-induced alterations in apolipoproteins and their associations with maternal metabolic risk factors and offspring birth outcomes: a preconception and l... by Li Chen, Karen Mei-Ling Tan, Melvin Khee-Shing Leow, Kok Hian Tan, Jerry Kok Yen Chan, Shiao-Yng Chan, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Markus R. Wenk, Sartaj Ahmad Mir

“…Higher maternal ApoC-I and ApoC-III concentrations at preconception were significantly associated with shorter gestational age of the offspring. …”
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Effect of acupoint application combined with acupoint massage on constipation of liver-qi stagnation after replantation of severed fingers (穴位贴敷联合按摩在断指再植术后肝郁气滞型便秘患者中的应用效果研究)... by TIAN Miaomiao (田苗苗), XIAO Junyan (肖俊艳)

“…Conclusion Acupoint application combined with massage has a significant effect on liver-qi stagnation constipation after finger replantation, which can effectively improve the constipation symptoms and relieve patients' negative emotion such as anxiety and depression. …”
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[Artículo traducido] Análisis retrospectivo de supervivencia del uso de vástagos modulares cónicos no cementados para la revisión en fracturas periprotésicas tipo B de Vancouver. ¿... by J. Lixa, P. Vieira, P. Pereira, A. Pinho, M. Seara, A. Sousa, L. Vieira

“…Conclusion: Survivorship of an uncemented modular stem (MRP-Titan) in revision for PHF is significantly reduced by episodes of instability.…”
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Xixin Decoction’s novel mechanism for alleviating Alzheimer’s disease cognitive dysfunction by modulating amyloid-β transport across the blood–brain barrier to reduce neuroinflamma... by Chaokai Yang, Enlong Zhao, Hu Zhang, Liqi Duan, Xinyue Han, Hongli Ding, Yan Cheng, Dengkun Wang, Dengkun Wang, Dengkun Wang, Xiaojing Lei, Xiaojing Lei, Xiaojing Lei, Yongchang Diwu, Yongchang Diwu, Yongchang Diwu

“…Modern clinical studies have demonstrated its significant therapeutic effects in treating Alzheimer’s disease (AD) without notable adverse reactions. …”
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Exometabolomic exploration of culturable airborne microorganisms from an urban atmosphere by R. Jin, W. Hu, W. Hu, P. Duan, M. Sheng, D. Liu, Z. Huang, M. Niu, L. Wu, J. Deng, P. Fu, P. Fu

“…These microbial exometabolites predominantly comprised aliphatic/peptide-like and carboxyl-rich alicyclic molecule (CRAM)-like compounds. Significant variations in metabolites were observed among different microbial strains. …”
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Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis by Bing Xia, Yan-lin Lu, Jin Peng, Jing-wei Liang, Fang-qin Li, Jiu-yang Ding, Chang-wu Wan, Cui-yun Le, Jia-lin Dai, Jie-Wang, Bing Guo, Jiang Huang

“…Following DNMT1 inhibition, the DC05 group displayed a significant decrease in methylation across all six CpG sites compared to the C57 and AS groups. …”
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Макроморфологічні та мікроморфологічні дослідження ґрунтів Консулівського городища (І ст. до н. е. – ІІ ст. н. е.)... by Жанна Матвіїшина, Анатолій Кушнір, Надія Гаврилюк, Матера Марчин

“…The purpose of this article is to present new results of the study of soil samples from the Konsulivske settlement (1st century BC – 2st century AD), carried out by means of macromorphological and micromorphological analyses, and to show their significance for the archaeological characterisation of this settlement. …”
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Clinical observation of Shenfu injection in treating patients with internal watershed cerebral infarction (参附注射液治疗内分水岭脑梗死临床观察) by YANG Junhang (杨俊行), LI Jie (李杰), HU Zhe (胡哲), FU Jingna (付景娜), FENG Huimin (冯慧敏)

“…Conclusion Shenfu injection can significantly improve the blood flow velocity of the distal artery responsible for internal watershed cerebral infarction caused by middle cerebral artery stenosis, and reduce the severity of neurologic impairment. …”
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Surgeons are apprehensive to use DCD lungs despite similar post-transplant outcomes: A 20-year UNOS retrospective analysis by J. Sam Meyer, MSc, Oliver K. Jawitz, MD, MHS, Yury Peysakhovich, MD, Dan Aravot, MD, Matthew G. Hartwig, MD, MHS, Yaron D. Barac, MD, PhD

“…Odds of lung non-use between DBD and DCD donors were significantly associated with blood type, alcohol use, cause of death, smoking history, drug use, death circumstance, ethnicity, gender, hypertension, cancer, age, and lung pO2 on 100% P/F ratio (P < 0.001 for all variables). …”
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Impact de l’évaluation de la sédation sur la durée de ventilation mécanique en réanimation pédiatrique [Impact of sedation assessment on duration of mechanical ventilation in pedia... by Zakaria Zoheir Addou, Nabil Tabet Aoul, Abdessamad DALI ALI Dali-Ali

“…The average doses of hypnotics and analgesics were not significantly different. Conclusion-The use of a COMFORT B sedation scale allowed a reduction in the duration of mechanical ventilation with no change in the doses of hypnotics and analgesics. …”
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Analysis of depression status and nursing interventions in 163 patients with liver disease (163例肝病患者抑郁状况调查及护理干预效果分析) by WANG Yundan (望运丹), WANG Weixian (王伟仙), HU Deying (胡德英), LIU Yilan (刘义兰)

“…The screening scale has positive significance for screening patients with depression due to liver disease, and nursing intervention measures for patients with moderate to severe and severe depression due to liver disease have achieved certain results. …”
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Study on the application of modified Baduanjin exercise in accelerating rehabilitation of patients with tuberculosis of lumbar spine (改良八段锦在腰椎结核患者加速康复中的应用研究)... by TANG Ling (唐玲), TAN Jiarong (谭佳容), TANG Yang (唐阳), HE Jing (何静), MU Lianghai (穆浪海)

“…The VAS score of rest pain at affected limb in the study group was lower than that in the control at 1, 2 and 4 weeks after intervention, respectively (P＜0. 05). There was a significant difference in degree of limitation of straight-leg raising between two groups at 1, 2 and 4 weeks after intervention, respectively (P＜0. 05). …”
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Kontribusi Mazhab Teologis Mu'tazilah Dalam Perkembangan Sastra Arab Era Aabbasiyah Studi Analisis Kritis Historis by Zulhelmi Zulhelmi, Hajjah Rafidah binti Haji Abdullah, Shuhaida Hanim binti Mohamad Suhane, Ashwaq Ismail S Batubara, Ashwaq Ismail S Batubara, Delami

“…The researcher concludes that the Mu'tazilah made significant contributions to the development of Arabic literature. …”
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Genetic Analysis of Reciprocal Crosses of Silkworm in New Iranian Lines and Hybrids by Shahla Nematollahian, Seyed Hossein Hosseini Moghaddam, Babak Rabiei, Seyed Ziaeddin Mirhoseini

“…In the other 22 pairs, either none of the traits or at most one trait had a significant difference (P<0.05). The results showed that the characteristics of cocoon weight and cocoon shell weight were more affected by reciprocal crossing. …”
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Combined Age with Mean Decrease Rates of Total Bilirubin and MELD Score as a Novel and Simple Clinical Predictor on 90-Day Transplant-Free Mortality in Adult Patients with Acute Li... by Di Jin, Kai Kang, Bing-zhu Yan, Jian-nan Zhang, Jun-bo Zheng, Zhi-hui Wang, Di Wu, Yu-jia Tang, Xin-tong Wang, Qi-qi Lai, Yang Cao, Hong-liang Wang, Yang Gao

“…Univariate analysis showed a significant difference in age, mean decrease rates of total bilirubin and MELD score mean increase rate of prothrombin activity, decrease rates of total bilirubin and MELD score, and increase rate of prothrombin activity after the first PE between the death group and survival group. …”
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Analysis of compliance with wearing hospital gowns and its influencing factors among inpatients in a certain third-grade class-A hospital in Changsha (长沙市某三甲医院住院患者病服穿着依从性及影响因素分析)... by HUANG Siting (黄思婷), HAN Huiwu (韩辉武), LI Bingfa (李兵发), ZHANG Jinghui (张京慧)

“…Totally 1520 patients (40. 97%) reported the poor compliance with wearing hospital gowns. There was a significant difference in compliance with wearing hospital gowns between patients from general departments (60. 53%) and severe departments (39. 47%), female (59. 21%) and male patients (40. 79%), patients aged less than 18 years (54. 62%) and 18 years or older (34. 52%) and patients with junior-high-school or lower education level (59. 87%) and with senior-high-school or higher education level (40. 13%)(P<0. 05, respectively). …”
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Ophthalmological monitoring in patients with hypertension and coronary heart disease by L.K. Moshetova, I.V. Vorobyeva, A. Dgebuadze, O.D. Ostroumova, A.V. Arablinskiy, E.P. Delver, A.A. Belogurov

“…</i> </p> <p> <i><b>Conclusions</b>: in patients with hypertension and CHD with coronary artery stenosis, significant (p&lt;0.05) reduction in BCVA, MS, SCP VD, DCP VD, and choriocapillaris VD and increase in CMT and FAZ area were detected compared to healthy individuals. …”
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