Coastal drowning: A scoping review of burden, risk factors, and prevention strategies. by William Koon, Amy Peden, Jasmin C Lawes, Robert W Brander

“…<h4>Objective</h4>Coastal drowning is a global public health problem which requires evidence to support safety initiatives. The growing multidisciplinary body of coastal drowning research and associated prevention countermeasures is diverse and has not been characterised as a whole. …”
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Development and validation of the age-associated dementia policy (AgeD-Pol) computer simulation model in the USA and Europe by Anand Viswanathan, Lee H Schwamm, Krishna P Reddy, Emily P Hyle, Fatma M Shebl, Kenneth A Freedberg, Julia H A Foote, Yiqi Qian, Shibani S Mukerji, Nattanicha Wattananimitgul, Ankur Pandya

“…We compared model-projected AAD cumulative incidence and mortality with published cohort data using mean absolute percentage error (MAPE) and root-mean-square error (RMSE).Results In internal validation, the AgeD-Pol model provided a good fit to the ACT cohort for cumulative AAD incidence, 10.4% (MAPE, 0.2%) and survival, 66.5% (MAPE, 8.8%), after 16 years of follow-up among those initially aged 65–69 years. In the external validations, the model-projected lifetime cumulative incidence of AAD was 30.5%–32.4% (females) and 16.7%–23.0% (males), using data from the Framingham and Rotterdam cohorts, and AAD cumulative incidence was 21.5% over 14 years using KPNC data. …”
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Tibial tubercle transfer SurgeRy and physiothErapy Versus physIotherapy only for chronic paTellofemorAL paIn: study protocol for a randomiSed controllEd trial (REVITALISE) by Myrthe P. F. van de Ven, Martin Ophey, Victor van de Graaf, Sebastiaan A. W. van de Groes, Marijn Sinkeldam, Charlotte H. W. Wijers, Sander Koëter

“…However, to date, no randomised controlled trials (RCT) have compared TTT combined with a physiotherapy (PT) programme to PT alone as the initial treatment for PFP. Methods A single-centre nonblinded RCT in 40 patients with chronic PFP (> 1 year) and tibial tubercle-trochlear groove (TT-TG) > 15 mm will be randomised to either TTT followed by PT or to PT alone in a 1:1 ratio in a concealed manner. …”
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Brief Report: Clinical Characteristics and Outcomes of Patients With Thoracic SMARCA4-Deficient Undifferentiated Tumors by Alissa J. Cooper, MD, Andrea Arfe, PhD, Biagio Ricciuti, MD, Andréanne Gagné, MD, PhD, Lynette M. Sholl, MD, Alessandro Di Federico, MD, Mark M. Awad, MD, PhD, Mihaela Aldea, MD, PhD, Maria Rosa Ghigna, MD, Miruna Grecea, MD, Phoebe Clark, MS, Jamie E. Chaft, MD, Mark G. Kris, MD, Gregory J. Riely, MD, Charles M. Rudin, MD, PhD, Ibiayi Dagogo-Jack, MD, Mari Mino-Kenudson, MD, Lingzhi Hong, MD, PhD, Neda Kalhor, MD, Natalie Vokes, MD, Anita Bowman, MS, Soo-Ryum Yang, MD, Natasha Rekhtman, MD, PhD, Adam J. Schoenfeld, MD

“…Results: We identified 92 patients with SMARCA4-UTs; 58 (63%) had stage IV disease at diagnosis and 16 (17%) developed recurrent or metastatic disease after initial diagnosis. Median overall survival from metastatic diagnosis was 7.3 (95% confidence interval [CI]: 4.6–12.8) months. …”
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Conservative Treatment of Spontaneous Rectus Sheath Hematomas: Single Center Experience and Literature Review by Banu Karapolat, Halil Afsin Tasdelen, Hatice Ayca Ata Korkmaz

“…The most common triggering factor was severe cough and the most common initial symptom acute abdominal pain (71.4%). In physical examinations, the entire patients had generalized abdominal tenderness, 10 (71.4%) voluntary guarding and 7 (50%) a right lower quadrant mass. …”
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Hyperglycemia and Correlated High Levels of Inflammation Have a Positive Relationship with the Severity of Coronavirus Disease 2019 by Wen Zhang, Chuanwei Li, Yu Xu, Binfeng He, Mingdong Hu, Guoqiang Cao, Li Li, Shuang Wu, Xia Wang, Chun Zhang, Jianping Zhao, Jungang Xie, Zihui Xu, Qi Li, Guansong Wang

“…Hyperglycemia was positively correlated with higher inflammation levels and more severe illness, and it is a risk factor for the increased severity of COVID-19. The initial measurement of plasma glucose levels after hospitalization may help identify a subset of patients who are predisposed to a worse clinical course.…”
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Challenges and Strategies Adopted for Remote Teaching of Biochemistry During the COVID-19 Pandemic: Protocol for a Scoping Review by Tatiane Iembo, Helena Landim Gonçalves Cristóvão, Emerson Roberto dos Santos, André Bavaresco Gonçalves Cristóvão, Nathália Bavaresco Gonçalves Cristóvão, Cíntia Canato Martins, Natália Almeida de Arnaldo Silva Rodrigues Castro, Fernando Nestor Facio Júnior, Antônio Hélio Oliani, Alba Regina de Abreu Lima, Vânia Maria Sabadoto Brienze, Doroteia Rossi Silva Souza, Júlio César André

“…ResultsStarting in February 2022, the scoping review protocol was scheduled for completion by July 2024. From an initial pool of 1171 results, 85 articles were selected, with duplicate verification pending for the subsequent phase of the project. …”
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A novel cryopreservation solution for adipose tissue based on metformin by Yaping Deng, Xin Liu, Xichao Jian, Yan Zhang, Yinchi Hou, Suyun Hou, Fang Qi, Shune Xiao, Chengliang Deng

“…This study investigated the protective effect of a new cryopreservation solution combining trehalose, glycerol, and metformin on adipose tissue. Methods This study initially examined the effect of various concentrations of metformin (0, 1, 2, 4, and 8 mM) on oxidative damage in adipose tissue to identify the optimal concentration. …”
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Vers un alpinisme expérimental ? by Anne-Laure Amilhat Szary

“…En 2011 et 2012, deux alpinistes ont fait le projet de parcourir les frontières politiques d’un pays alpin, sans avoir particulièrement connaissance du fait que ces initiatives se trouveraient liées par la coïncidence des calendriers. …”
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Time-dependent, patient-centered perceptions of quality measures for total joint arthroplasty: a cross-sectional, choice modeling study by Jacie L. Lemos, Jessica M. Welch, Derek F. Amanatullah, Lauren M. Shapiro, Alex H. S. Harris, Robin N. Kamal

“…Conclusions Matching outcome assessments with how patients assess their quality of care throughout the TJA recovery process can inform phase-specific quality improvement initiatives and value definitions. Activities of daily living should be measured across phases of care and into long-term recovery. …”
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The interphase period “germination–heading” of 8x and 6x triticale with different dominant Vrn genes by P. I. Stepochkin, A. I. Stasyuk

“…It was shown that plants of the hybrid populations 8xVrnA1× ‘Sears 57’ and 8xVrnD1× ‘Sears 57’ carrying the dominant alleles Vrn-A1a and Vrn-D1a, respectively, have a shorter duration of the “germination–heading” interphase period than the initial parental forms of primary 8x triticale. The short interphase period of “germination–heading” of the 6x triticale is a valuable breading trait for the creation of early maturing and productive genotypes of triticale.…”
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Propiedades y aplicaciones de los cementos alcalinos Properties and uses of alkali cements by Ana Fernández-Jiménez, Ángel Palomo

“…So depending on the type of alkali activator that is used and after a previous thermal curing, the resulting material will show an interesting list of properties and features that includes: high initial mechanical strengths (under flexure and compression), low drying shrinkage, and a very good matrix-steel bonding, as well as an excellent strength to acid attack and an excellent behaviour when is exposed to fire. …”
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Examining the effect of direct-from-blood bacterial testing on antibiotic administration and clinical outcomes: a protocol and statistical analysis plan for a pragmatic randomised... by Li Wang, Wesley H Self, Todd W Rice, Matthew W Semler, Karen F Miller, Cheryl L Gatto, Andrea Fletcher, Romney M Humphries, Joanna L Stollings, Adrienne Baughman, Jakea Johnson, Edward T Qian, Mary Lynn Dear, David C Gaston, Ariel A Lewis, George E Nelson, Benjamin J Ereshefsky, Matthew A Christensen, Ritu Banerjee, Dan Albert, Alison Benton, Laura Bobbitt, Carleigh Burns, Timothy Duff, David C. Gaston, MLS Sharon Glover, Allyson Hobbie, Austin Ing, Gabriel Kemp, Sheryl Mangrum, Geoff Mavrak, Kelly Moser, David Mulherin, Shannon Pugh, Matthew Rodgers, Chrissie Schaeffer, Adam Turner, Sabrina Shipman, Halden Z VanCleave, Hamilton Wen Li Wang, LaKeysha Wiggins

“…The trial will enrol 500 adult patients presenting to the emergency department at Vanderbilt University Medical Center with suspected bacterial infection who have been initiated on empiric intravenous vancomycin. Eligible patients are randomised 1:1 to receive Food and Drug Administration-approved direct-from-blood bacterial testing in addition to blood cultures or blood cultures alone. …”
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Persistence and emergence of X4 virus in HIV infection by Ariel D. Weinberger, Alan S. Perelson

“…Our analysis shows that X4 avoids competitive exclusion from an initially fitter R5 virus due to X4v unique ability to productively infect nave CD4+ T cells. …”
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Engineering Soil Quality and Water Productivity Through Optimal Phosphogypsum Application Rates by Anrong Luo, Jun Li, Yanan Xiao, Zijian He, Jiaping Liang

“…The comprehensive benefits of phosphogypsum initially increased and then decreased, with an optimal application rate of 0.45% determined through TOPSIS, a method that ranks alternatives based on their proximity to an ideal solution, considering factors including soil quality, crop yield and IWP. …”
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Numerical Simulation of Two-Phase System of “Combustible Liquid – Solid Fuel” Combustion in a Fixed Bed by K. V. Dobrego, I. A. Koznacheev

“…But the time of establishing the quasi-stationary velocity of the front to the steady-state value at the initial stage is much less in case of bottom side ignition. …”
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Disclosure of oral pre-exposure prophylaxis use for HIV prevention among women enrolled in a contraceptive study: qualitative findings from Durban, South Africa by Ivana Beesham, Mags Beksinska, Cecilia Milford, Cecilia Milford, Leila E. Mansoor

“…Here, we describe disclosure of PrEP use among young women enrolled in a contraceptive study.MethodsIn this qualitative study, we conducted semi-structured, in-depth, face-to-face interviews with 13 women aged 18–25 years who initiated oral PrEP for HIV prevention during the Evidence for Contraceptive Options and HIV Outcomes (ECHO) Trial. …”
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Artificial intelligence in suicide prevention: Utilizing deep learning approach for early detection by Vikas Gaur, Gaurav Maggu, Khushboo Bairwa, Suprakash Chaudhury, Sana Dhamija, Tahoora Ali

“…Aim: Our primary objective was to construct an artificial intelligence (AI) model employing an artificial neural network (ANN) architecture to predict students at risk of suicidal tendencies. This initiative was prompted by the necessity to implement a proactive and technologically driven strategy for identifying competitive exam-bound students facing heightened vulnerability. …”
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Prevalence and Factors Associated with Drooling in Parkinson’s Disease: Results from a Longitudinal Prospective Cohort and Comparison with a Control Group by Diego Santos-García, Teresa de Deus Fonticoba, Carlos Cores Bartolomé, Maria J. Feal Painceiras, Maria Cristina Íñiguez-Alvarado, Silvia Jesús, Maria Teresa Buongiorno, Lluís Planellas, Marina Cosgaya, Juan García Caldentey, Nuria Caballol, Ines Legarda, Jorge Hernández Vara, Iria Cabo, Lydia López Manzanares, Isabel González Aramburu, Maria A. Ávila Rivera, Víctor Gómez Mayordomo, Víctor Nogueira, Víctor Puente, Julio Dotor García-Soto, Carmen Borrué, Berta Solano Vila, María Álvarez Sauco, Lydia Vela, Sonia Escalante, Esther Cubo, Francisco Carrillo Padilla, Juan C. Martínez Castrillo, Pilar Sánchez Alonso, Maria G. Alonso Losada, Nuria López Ariztegui, Itziar Gastón, Jaime Kulisevsky, Marta Blázquez Estrada, Manuel Seijo, Javier Rúiz Martínez, Caridad Valero, Mónica Kurtis, Oriol de Fábregues, Jessica González Ardura, Ruben Alonso Redondo, Carlos Ordás, Luis M. L. López Díaz, Darrian McAfee, Pablo Martinez-Martin, Pablo Mir, Study Group COPPADIS

“…Drooling is frequent in PD patients even at the initial onset of the disease and is associated with a greater motor severity and NMS burden.…”
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Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes by Laura J. Andreasen, Rikke K. Kirk, Christian Fledelius, Mark A. Yorek, Jens Lykkesfeldt, Thorbjorn Akerstrom

“…During the 12-week treatment period, blood glucose and body weight were monitored weekly, whereas Hargreaves’ test was performed four, eight, and 12 weeks after treatment initiation. At study termination, several blood parameters, body composition, and neuropathy endpoints were assessed. …”
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