The impact of the COVID-19 pandemic on the research activity and working experience of clinical academics, with a focus on gender and ethnicity: a qualitative study in the UK by Carmen Soto, Jessica Elizabeth Morgan, Paul Crampton, Paul Alexander Tiffin, Gabrielle M Finn, Amelia Kehoe, Ellie Taylor, John AG Buchanan, Abisola Olatokunbo Balogun

“…Four major themes were identified in relation to the initial impact of COVID-19 on clinical academics: opportunities, barriers, personal characteristics and social identity, and fears and uncertainty. …”
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Kinetics, central composite design and artificial neural network modelling of ciprofloxacin antibiotic photodegradation using fabricated cobalt-doped zinc oxide nanoparticles by Asmaa I. Meky, Mohamed A. Hassaan, Mohamed A. El-Nemr, Howida A. Fetouh, Amel M. Ismail, Ahmed El Nemr

“…The optimal parameters of pH 6.486, 134.39 rpm shaking speed, 54.071 mg catalyst dose, and 31.04 ppm CIPF initial concentration resulted in the highest CIPF degradation efficiency (93.99%). …”
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Rationale and design of APOLLO: a personalized rehAbilitation PrOgram in aLLOgeneic bone marrow transplantation by Edith Pituskin, Stephen Foulkes, Rachel J. Skow, Thomas McMurtry, Calvin Kruger, Janet E. Bates, Daena Lamoureux, Joseph Brandwein, Elena Lieuw, Cynthia Wu, Nancy Zhu, Peng Wang, Daniel Sawler, Minakshi Taparia, Marlene Hamilton, Tiffany Comfort-Riddle, Tara Meyer, Gabor T. Gyenes, Ian Paterson, Carla M. Prado, Mark J. Haykowsky, Justin G. Greiner, Margaret L. McNeely, Puneeta Tandon, Richard B. Thompson

“…Patients undergoing allogeneic bone marrow transplantation (allo-BMT) are often critically ill at initial diagnosis and with necessary sequential treatments become increasingly frail and deconditioned. …”
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Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19Research in context by Hui Ying, Xueyan Wu, Xiaojing Jia, Qianqian Yang, Haoyu Liu, Huiling Zhao, Zhihe Chen, Min Xu, Tiange Wang, Mian Li, Zhiyun Zhao, Ruizhi Zheng, Shuangyuan Wang, Hong Lin, Yu Xu, Jieli Lu, Weiqing Wang, Guang Ning, Jie Zheng, Yufang Bi

“…Methods: We conducted a Mendelian randomization (MR) and colocalization analysis using 26,597 single-cell expression quantitative trait loci (sc-eQTL) to proxy effects of expressions of 16,597 genes in 14 peripheral blood immune cells and tested them against four COVID-19 outcomes from COVID-19 Genetic Housing Initiative GWAS meta-analysis Round 7. We also carried out additional validations including colocalization, linkage disequilibrium check and host–pathogen interactome predictions. …”
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Pituitary Stalk Interruption Syndrome: A Case and Literature Review by Anuja Choure, MD, Leena Shahla, MD

“…The magnetic resonance imaging of the brain revealed an ectopic posterior pituitary with a partially empty sella, absence of the pituitary stalk, and a small anterior pituitary. The patient was initiated on replacement hormones with improvement in her symptoms. …”
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Characterization, Molecular Identification and Antimicrobial Susceptibility Testing of Diarrheagenic Escherichia coli Isolated from Diarrhea Infected Patients Around Dhaka City by Fahima Akter, Md. Shamimuzzaman, Susmita Roy Chowdhury, Faria Islam, Rajib Kanti Roy

“…Objective: This research aimed to determine and evaluate the vulnerability of diarrheagenic E. coli to certain antibiotics isolated from hospitalized diarrhea-infected patients in Dhaka city. Methodology: After initial cultural isolation and identification through BAM, E. coli species were identified automatically via VITEK 2 COMPACT ID-GN card. …”
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The prevalence and correlates of biomarker positive unhealthy alcohol use among women living with and without HIV in San Francisco, California. by Jennifer P Jain, Yifei Ma, Carol Dawson-Rose, Glenn-Milo Santos, Alvina Han, Jennifer Price, Judith A Hahn, Phyllis C Tien

“…To optimize alcohol related health care, there is a need to consider approaches to improve ascertainment of unhealthy alcohol use, especially among Black/African American women and those living with liver disease, so that interventions can be initiated.…”
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Current Situation of Illegal Usage of Special Expertise while Investigating Thefts by O. V. Haidar

“…The emphasis has been placed on the objects that should be initially examined during the investigation of the secret theft of someone else’s property, combined with the penetration into the premises. …”
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Towards quantifying exfiltration from in situ sanitary sewer pipes by John F. Griffith, Joshua A. Steele, Adriana Gonzalez-Fernández, Kenneth C. Schiff

“…This study represents an initial effort at measuring exfiltration from in situ sanitary pipes. …”
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Continuous Speech-Based Fatigue Detection and Transition State Prediction for Air Traffic Controllers by Susmitha Vekkot, Surya Teja Chavali, Charan Tej Kandavalli, Rama Sai Abhishek Podila, Deepa Gupta, Mohammed Zakariah, Yousef Ajami Alotaibi

“…The main contributions of this work are the creation of a continuous speech ATC dataset and the identification of a lightweight optimum feature set for fatigue classification from ATC speech. For the initial task, the classification of raw speech signals into fatigue and non-fatigue categories was performed using the top-10 best features selected from the openSMILE feature set. …”
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Romanul Arhanghelii și „epoca de aur” a mineritului din Țara Moților by Alexandru Dumitriu

“…The writer who established this topos is Ion Agârbiceanu, in his novel The Archangels from 1913–1914, the first literary work of such magnitude dedicated to the Romanian mining. The novel was initially published in instalments, in the “Luceafărul” literary magazine (Sibiu) in 1913. …”
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Do community-based digital health inclusion programmes contribute to tackling health inequalities in disadvantaged population groups?: a qualitative study of experiences of a city-... by Shoba Poduval, Lily Arnold, Emma Carta, Danielle Nimmons, Irene Stratton, Michael Shaw, Katherine Bradbury, Fiona Stevenson

“…Our data add to the public health, primary care and digital health research by proposing an initial programme theory for how Digital Health Hubs may reduce health inequalities, and recommendations for evaluation which consider short-, medium- and long-term outcomes, and contextual factors which are likely to be crucial to Digital Health Hubs’ effectiveness.…”
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Evaluation of a transdiagnostic mental health intervention in German primary care: study protocol for a parallel-group, two-arm, cluster randomised controlled pilot study by Christopher Ebert, Marie Vogel, Jochen Gensichen, Hanna Reif, Lena Grögor, Lukas Junker, Thomas Ehring, Alkomiet Hasan, Stefan Leucht, Kirsten Lochbühler, for the POKAL-Group

“…Self-report questionnaires will be completed before treatment initiation (only patients) and after treatment completion (patients and general practitioners) to assess feasibility and acceptability (i.e., treatment recruitment, delivery, response, effectiveness, unintended consequences and maintenance) as well as potential effectiveness (i.e., change in transdiagnostic factors). …”
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Real-world data of dacomitinib as first-line treatment for patients with EGFR-mutant non-small-cell lung cancer by Ji Eun Shin, Hyun Ae Jung, Sehhoon Park, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn, Byoung Yong Shim

“…Grade 3 or higher adverse events were observed in 7.2% of patients. Initially administered at a dose of 45 mg, dose reduction was necessary for 85.6% of patients, with a final dosage of 30 mg in 49.0% and 15 mg in 36.6% of cases. …”
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Characterization, Molecular Identification and Antimicrobial Susceptibility Testing of Diarrheagenic Escherichia coli Isolated from Diarrhea Infected Patients Around Dhaka City by Fahima Akter, Md. Shamimuzzaman, Susmita Roy Chowdhury, Faria Islam, Rajib Kanti Roy

“…Objective: This research aimed to determine and evaluate the vulnerability of diarrheagenic E. coli to certain antibiotics isolated from hospitalized diarrhea-infected patients in Dhaka city. Methodology: After initial cultural isolation and identification through BAM, E. coli species were identified automatically via VITEK 2 COMPACT ID-GN card. …”
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“It’s a delicate balance”: clinicians’ experiences of providing heroin-assisted treatment by Rune Ellefsen, Silvana De Pirro, Vegard Haukland, Linda Elise Couëssurel Wüsthoff, Espen Ajo Arnevik

“…The challenging aspects were dosing and overdose risk; rule enforcement and aggression management; and the difficulty of initiating treatments beyond medication and harm reduction. …”
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Spleen tyrosine kinase inhibitors disrupt human neutrophil swarming and antifungal functions by Alex Hopke, Adam L. Viens, Natalie J. Alexander, Seok Joon Mun, Michael K. Mansour, Daniel Irimia

“…We show that inhibitors that interfere with PI3Ky signaling disrupt the regulation of the initiation of swarming, while the activation of JNK signaling is essential for the activation of biochemical antifungal functions. …”
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Dissolved Mn(III) is a key redox intermediate in sediments of a seasonally euxinic coastal basin by R. Klomp, R. Klomp, O. M. Żygadłowska, M. S. M. Jetten, V. E. Oldham, N. A. G. M. van Helmond, N. A. G. M. van Helmond, C. P. Slomp, C. P. Slomp, W. K. Lenstra, W. K. Lenstra

“…Modeled benthic release of Mn mainly occurs as dMn(III)-L when bottom waters are oxic, as Mn(II) upon initial bottom-water euxinia and as both Mn(II) and dMn(III)-L when the euxinia becomes persistent. …”
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Real-world use of tafasitamab preceding CD19-directed chimeric antigen receptor T-cell therapy for relapsed or refractory diffuse large B-cell lymphoma by Narendranath Epperla, Loretta J. Nastoupil, Bruce Feinberg, John Galvin, Prathamesh Pathak, Theresa Amoloja, Danielle Gentile, Kim Saverno

“…Median (first quartile [Q1]–third quartile [Q3]) follow-up time since tafasitamab initiation was 26.1 (18.0–28.0) and after CAR-T was 9.3 (1.9–16.7) months. …”
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Effect of the host-specific toxin SnTOX3 from Stagonospora nodorum on ethylene signaling pathway regulation and redox-state in common wheat by S. V. Veselova, G. F. Burkhanova, T. V. Nuzhnaya, S. D. Rumyantsev, I. V. Maksimov

“…Our results suggest that NE SnTox3 influences ethylene biosynthesis and signaling, thereby regulating redox metabolism in infected wheat plants as necessary for successful host colonization at the initial phases of infection, which ultimately leads to extensive lesions due to fast pathogen reproduction.…”
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