Prediction-based prompt levothyroxine replacement to prevent a hypothyroid state after immune-related adverse events involving the thyroid gland by Ichiro Yamauchi, Takuro Hakata, Taku Sugawa, Daisuke Kosugi, Haruka Fujita, Kentaro Okamoto, Yohei Ueda, Toshihito Fujii, Daisuke Taura, Norio Harada, Nobuya Inagaki

“…We treated 4 such patients with prompt LT4 replacement, characterized by LT4 initiation after thyrotoxicosis improvement and quick dose titration. …”
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Data sharing: experience of accessing individual patient data from completed randomised controlled trials in vascular and cognitive medicine by Philip M Bath, Alan A Montgomery, Lisa J Woodhouse, Polly Scutt

“…Following contact, positive initial responses were received from 92 researchers, resulting in IPD being shared for 78 trials. …”
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Intermittent versus daily oral iron folic acid supplementation and pregnancy outcome in low- and middle-income countries: a systematic review and meta-analysis of experimental stud... by Serawit Lakew Chillo, Endrias Markos Woldesemayat, Mesay Hailu Dangisso

“…However, either early initiation or frequently intermittent regimen in the subgroup analysis showed no difference in hemoglobin levels. …”
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Transcriptional landscape and predictive potential of long noncoding RNAs in peritoneal recurrence of gastric cancer by Xiao-Xia Cai, Guo-Ming Chen, Zi-Qi Zheng, Yi-Xin Yin, Shuang Wang, Li Qiao, Xiao-Jiang Chen, Bai-Wei Zhao, Jin-Ling Duan, Cheng-Cai Liang, Ruo-Peng Zhang, Cheng-Zhi Wei, Fei-Yang Zhang, Bo-Wen Huang, Ze-Xian Liu, Zhi-Wei Zhou, Dan Xie, Mu-Yan Cai, Shu-Qiang Yuan, Yuan-Fang Li, Run-Cong Nie

“…Subsequently, we demonstrated that one of these lncRNAs, CASC15, promoted the invasion and migration of GC cells in vitro and facilitated the PM of GC cells in vivo, initially verifying that lncRNAs contribute to the PM of GC. …”
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Empowering medical students with AI writing co-pilots: design and validation of AI self-assessment toolkit by Laleh Khojasteh, Reza Kafipour, Farhad Pakdel, Jayakaran Mukundan

“…Next, an analysis of medical students' reflection papers was undertaken to gain insights into their experiences using AI-powered tools for writing feedback. Based on these initial steps, a preliminary version of the self-assessment toolkit was devised. …”
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Unveiling The Myth of High Recurrence Rate of Extracranial Arteriovenous Malformations of The Head and Neck: Systematic Review of Case Reports and Case Series [version 2; peer revi... by Sagung Rai Indrasari, Danu Yudistira, Camelia Herdini, Agustian Winarno Putra

“…Our analysis focused on key endpoints, specifically the recurrence rates of head and neck AVMs following various treatment approaches. Results Out of the initial pool of 108 screened articles, a total of 83 patients were deemed suitable for inclusion in the literature review. …”
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Acute Attack of Pseudogout with the Wide Lesion in Lumbar Spondylolytic Spondylolisthesis by Hironari Kaneyama, Yuichiro Morishita, Osamu Kawano, Takuaki Yamamoto, Takeshi Maeda

“…The patient was suspected of having pyogenic arthritis of the lumbar spine in initial diagnosis. A total of 1.2 ml of fluid with a murky, pus-like synovial effusion was aspirated from the L3-4 interspinous space under the fluoroscopic image. …”
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MAO-B Polymorphism Associated with Progression in a Chinese Parkinson’s Disease Cohort but Not in the PPMI Cohort by Shi-Shuang Cui, Ling-Yu Wu, Gen Li, Juan-Juan Du, Pei Huang, Jin Liu, Yun Ling, Kang Ren, Zhong-Lue Chen, Sheng-Di Chen

“…This study investigated genetic associations with progression based on 30 PD risk loci common in a longitudinal cohort of Chinese PD patients and the Parkinson’s Progression Markers Initiative (PPMI) cohort. Methods. PD patients from the true world (TW) Chinese PD longitudinal cohort and the PPMI cohort with demographic information and assessment scales were assessed. …”
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Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans by Mariano A. Aufiero, Li-Yin Hung, De'Broski R. Herbert, Tobias M. Hohl

“…However, when we compared Mpeg1−/− mice with co-housed Mpeg+/+ littermate controls, these differences were no longer observed, indicating that initial findings were likely influenced by differences in the murine genetic background or the microbiota composition. …”
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Dynamic reconfiguration of default and frontoparietal network supports creative incubation by Ziyi Li, Ze Zhang, Tengteng Tan, Jing Luo

“…Using an incubation paradigm, we temporarily disengaged participants from the initial creative ideation task and required them to conduct two different distraction activities (moderately-demanding: 1-back working memory task, non-demanding: 0-back choice reaction time task), then returned them to the previous creative task. …”
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Saudi urologists’ treatment pattern for high-risk Bacillus Calmette–Guérin naïve and Bacillus Calmette–Guérin unresponsive nonmuscle invasive bladder cancer by Mohammad Alghafees, Mohamad Abou Chakra, Abdullah Alkhayal, Mohamad Moussa, Mohammad Alkhamees, Bader Alsaikhan, Ahmed Alasker, Abdulrahman Alsayyari, Abdullah Alsaghyir, Ali Alkahtani, Michael A. O'Donnell

“…To properly select treatment for this condition, there is an urgent need to implement initiatives to open clinical trials and provide guideline-based protocols to Saudi Arabia and throughout the Arab world.…”
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A systemic approach to identifying sustainable community-based interventions for improving adolescent mental health: a participatory group model building and design protocol by Megan Keenan, Leanne Freeman, Ediane Santana de Lima, Katie Potter, Tim Hobbs, Ellis Ballard, Peter Fonagy

“…Kailo responds to this issue with a community-based participatory and systemically informed strategy, perceiving mental health and well-being as a dynamic state shaped by the interplay of broader health determinants. The initiative works to explore, define and implement locally relevant solutions to challenges shaping the mental health and well-being of young people. …”
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À la recherche des points-clefs de Gilbert Simondon autour d’un système d’information géographique by Stephan Kowal

“…The main topic of this article is the development of the Canada Geographic Information System (CGIS) initiated in 1962, an integrated computer system capable of combining national statistical information and cartographic documents, specifically intended for decision-making in regional planning. …”
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Unravelling the transcriptomic symphony of muscle ageing: key pathways and hub genes altered by ageing and caloric restriction in rat muscle revealed by RNA sequencing by Gulam Altab, Brian J. Merry, Charles W. Beckett, Priyanka Raina, Inês Lopes, Katarzyna Goljanek-Whysall, João Pedro de Magalhães

“…This data may provide the initial evidence for several targets for potential future therapeutic interventions against sarcopenia.…”
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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlle... by Jeremy Chataway, Suvankar Pal, Charis Wong, Elizabeth Elliott, Jenna M Gregory, Siddharthan Chandran, Judith Newton, Shuna Colville, Maria Stavrou, Christopher J Weir, Nigel Stallard, Malcolm R Macleod, Michelle Steven, Richard Anthony Parker, Arpan R Mehta, Robert J Swingler, Mahesh K B Parmar, Rachel S Dakin, Jill Williamson

“…The first two drugs selected for evaluation in MND-SMART are trazodone and memantine.Methods and analysis Initially, up to 531 participants (177/arm) will be randomised 1:1:1 to oral liquid trazodone, memantine and placebo. …”
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KIDS CLUB: CHILD-FRIENDLY HOTEL MARKETING STRATEGY by Dian Pramita Sugiarti, I Gede Anom Sastrawan

“…Kids Club is an activity for child tourists offered by the hotel to provide children with activities to fill their free time while at the hotel. Kids Club is the initial consideration for family travelers before deciding which hotel to stay at. …”
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Investigation of Fe-Doped Graphitic Carbon Nitride-Silver Tungstate as a Ternary Visible Light Active Photocatalyst by Eid H. Alosaimi, Nadia Azeem, Noor Tahir, Asim Jilani, Muhammad Zahid, Salman. S. Alharthi, Javed Iqbal, Muhammad Yaseen, Zulfiqar Ahmad Rehan, Imran Shahid

“…The ternary nanocomposite (Fe-CN-AW) showed increased photodegradation efficiency (97%) within 120 minutes, at optimal conditions of pH = 8, catalyst dose = 50 mg/100 ml, an initial RhB concentration of 10 ppm, and oxidant dose 5 mM under sunlight irradiation. …”
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Resource potential of some species of the genus Miscanthus Anderss. under conditions of continental climate of West Siberian forest-steppe by O. V. Dorogina, O. Yu. Vasilyeva, N. S. Nuzhdina, L. V. Buglova, Yu. A. Gismatulina, E. V. Zhmud, G. A. Zueva, O. V. Kominа, Е. A. Tsybchenko

“…Introduction and investigation of Miscanthus species were initiated in the Central Siberian Botanical Garden of the Siberian Branch of the Russian Academy of Sciences (CSBG SB RAS, Novosibirsk, Russia) based on the grass and ornamental plant collection in the late 1990s. …”
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Pearl Millet Cover Crop Extract Inhibits the Development of the Weed <i>Ipomoea grandifolia</i> by Inducing Oxidative Stress in Primary Roots and Affecting Photosynthesis Efficienc... by Gislaine Cristiane Mantovanelli, Adriano Antônio Silva, Letycia Lopes Ricardo, Fernanda Lima Kagami, Jéssica Dario de Almeida, Mauro Cezar Barbosa, Márcio Shigueaki Mito, Isabela de Carvalho Contesoto, Paulo Vinicius Moreira da Costa Menezes, Gabriel Felipe Stulp, Beatriz Pereira Moreno, Francielli Alana Pereira Valeze, Rubem Silvério de Oliveira Junior, Debora Cristina Baldoqui, Emy Luiza Ishii Iwamoto

“…In roots of <i>I. grandifolia</i> seedlings, at the initial development stage, EAF induced oxidative stress and increased electrolyte leakage. …”
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Severe Lipoatrophy in a Growth Hormone Deficient Toddler Girl Treated with a Non-Pegylated Long-Acting Growth Hormone by Atilla Büyükgebiz, And Demir

“…Methods: This case report discusses a 5.5-year-old girl born at 40 weeks of gestation with a birth weight of 2300 g, diagnosed with idiopathic short stature and borderline GH secretion, along with a history of mild intrauterine growth retardation. Results: After initiating treatment with somatrogon, a non-pegylated fusion protein formulation of LAGH at the standard dose of 0.66 mg/kg body weight weekly, administered by her family, she developed localized lipoatrophy at the injection site within eleven weeks. …”
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