Prevalence of prescribing topical corticosteroids to patients with lichen sclerosus following surgery for vulvar cancer: a survey among gynaecologic oncologists in The Netherlands by Féline O. Voss, Karelina L. Groenewegen, Hester Vermaat, Maaike C.G. Bleeker, Marc van Beurden

“…TCS were prescribed more often to patients with LSnoVSCC as compared to patients with LSVSCC (86% versus 52%, respectively, p < 0.001). If treatment was initiated, ultra-potent (class IV) TCS were most commonly prescribed for an indefinite period of time for both patient groups. …”
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No Effect of Anodal tDCS on Verbal Episodic Memory Performance and Neurotransmitter Levels in Young and Elderly Participants by Annegret Habich, Johannes Slotboom, Jessica Peter, Roland Wiest, Stefan Klöppel

“…While stimulation gains are more consistent in initial low performers, relying solely on behavioural measures to predict treatment benefits does not suffice for a reliable implementation of this method as a therapeutic option. …”
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General practitioner-centered rural obesity management: Design, protocol and baseline data of the German HAPpEN pragmatic trial by Marika Haderer, Reiner Hofmann, Tina Bartelmeß, Laura König, Constanze Betz, Mirna Al Masri, Alisa Bader, Natascha von Schau

“…Methods: HAPpEN is a 12-month, pragmatic single-arm, multicenter trial, informed by a formative survey, and initiated in April 2023 with 98 obese participants (body mass index, BMI ≥ 30 kg/m2) in Kulmbach, Germany. …”
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Donkey milk supplementation alleviates renal fibrosis of chronic kidney disease by enhancing anti-inflammatory ability by Cui Huimin, Wang Peng, Chen Man, Lin Hong, Zhao Yuxin, Pu Zhiyu, Yang Jianjun

“…ABSTRACT: Donkey milk, rich in essential nutrients, is not only able to meet the nutritional needs of patients with chronic kidney disease (CKD) according to the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative Clinical Practice Guideline for Nutrition in CKD, but also has strong anti-inflammatory properties. …”
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Influence of high-load shocks on achieving mainstream partial nitrification: Microbial community succession by Chenjie Jia, Jialin Li, Zhaoyang Li, Liang Zhang

“…High-throughput sequencing results showed that community diversity remained consistently high, and the community composition returned to its initial state following a minor succession during HLS1. …”
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Insights Into Antimicrobial Resistance From Dental Students in the Asia–Pacific Region by Saba Ghafoor, Gabriela Salvadori, Shiho Kino, Vy Thi Nhat Nguyen, Tam Thi-Thanh Nguyen, Miho Ishimaru, Antônio Pedro Ricomini-Filho, Cassiano Kuchenbecker Rösing, Dileep De Silva, Jun Aida, Belinda Farias Nicolau, Ratilal Lalloo, Roger Junges

“…To mitigate this issue, the implementation (followed by assessment) of local educational and antibiotic stewardship initiatives is warranted.…”
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A20 as a Potential Therapeutic Target for COVID‐19 by Yongyao Wu, Lilan He, Rong Li, Jiuxuan Li, Qing Zhao, Bin Shao

“…Patients suffering from COVID‐19 may exhibit immunosuppression in the initial stage of infection, while a cytokine storm can occur when the disease progresses to a severe stage. …”
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Impact of Soybean Bioactive Peptides on Growth, Lipid Metabolism, Antioxidant Ability, Molecular Responses, and Gut Microbiota of Oriental River Prawn (<i>Macrobrachium nipponense<... by Chang Yang, Bo Liu, Liangkun Pan, Dong Xia, Cunxin Sun, Xiaochuan Zheng, Peng Chen, He Hu, Qunlan Zhou

“…Three isonitrogenic and isolipidic diets were prepared as follows: R (reference diet with 32% fishmeal), CT (control diet with 22% fishmeal), and SBP (22% fishmeal with 1.25 g/kg soybean bioactive peptides). The prawns (initial biomass per tank 17 g) were randomly divided into three groups with four replicates. …”
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FTIR: A novel method for identifying fish gut contents by Abolfazl Aminimehr, Mohammad Amini Chermahini, Laleh Moosavi Dehmoordi

“…Introduction: If the composition of ingested food changes along the digestive tract in such a way that fish feces reflect the initial composition of the consumed food, there would be no need to sacrifice fish to identify the contents of their gut. …”
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Different influences of Mo and Mo2C additions on microstructure and properties of TiC-based cermets by Xiao-Dong Kang, Guo-Hua Zhang, Kuo-Chih Chou

“…The transverse rupture strength (TRS) initially increased but then decreased as the increase of Mo2C content. …”
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Prediction of Visual Acuity after anti-VEGF Therapy in Diabetic Macular Edema by Machine Learning by Ying Zhang, Fabao Xu, Zhenzhe Lin, Jiawei Wang, Chao Huang, Min Wei, Weibin Zhai, Jianqiao Li

“…Six different machine learning algorithms were used to predict VA in patients after anti-VEGF therapy. After the initial detailed investigation, we designed an optimization model for convenient application. …”
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Virtual screening assisted identification of a phytocompound as potent inhibitor against Candida lusitaniae; an in-silico study by Rimsha Timotheous, Habiba Naz, Usman Arif, Momna Toqeer Dar, Muhammad Farhan Sarwar, Mudassar Fareed Awan, Sajed Ali, Safia Obaidur Rab

“…Considering this fact, different phyto-compounds were opted in this research work to estimate their therapeutic efficiency against the secreted aspartyl proteinase (SAP) of C. lusitaniae since, it assists this pathogen in developing the infections. Initially, the structure of SAP was modelled for subsequent docking analysis. …”
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Bisecting GlcNAc modification of vesicular GAS6 regulates CAFs activation and breast cancer metastasis by Jing Li, Xueting Ren, Lin Cao, Kaixiang Min, Meng Wang, Shuai Lin, Lei Lei, Zengqi Tan, Xiaoliang Cheng, Xiang Li, Feng Guan

“…Abstract Background Cancer-associated fibroblasts (CAFs) are a pivotal component of the tumor microenvironment (TME), playing key roles in tumor initiation, metastasis, and chemoresistance. While glycosylation is known to regulate various cellular processes, its impact on CAFs activation remains insufficiently explored. …”
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Analysis of the Impact of Media on Premarital Sex in Central Division Kabale Municipality. by Kamusiime, Phabith

“…The study recommended that there should be implementation of religious education programs that focus on teaching the principles of the respective faith, including the importance of morality, chastity, and the sanctity of marriage because these programs should be tailored to different age groups and should involve active participation from religious leaders and community members, there should be establishment of youth empowerment initiatives that provide young people with opportunities for personal and spiritual development as this can include mentorship programs, skills training, and extracurricular activities that promote positive values and self-esteem and there should be fostering of community engagement through workshops, seminars, and discussions that address the challenges of premarital sex and provide guidance on building healthy relationships based on mutual respect and understanding.…”
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A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda by Keneth Iceland, Kasozi, Anne, Laudisoit, Lawrence Obado, Osuwat, Gaber El-Saber, Batiha, Naif E. Al, Omairi, Eric, Aigbogun, Herbert Izo, Ninsiima, Ibe Michael, Usman, Lisa M., DeTora, Ewan Thomas, MacLeod, Halima, Nalugo, Francis P., Crawley, Barbara E., Bierer, Daniel Chans, Mwandah, Charles Drago, Kato, Kenedy, Kiyimba, Emmanuel Tiyo, Ayikobua, Linda, Lillian, Kevin, Matama, Shui Ching, Nelly Mak, David, Onanyang, Theophilus, Pius, Linda, Lillian, Kevin, Matama, Shui Ching, Nelly Mak, David, Onanyang, Theophilus, Pius, David Paul, Nalumenya, Robinson, Ssebuufu, Nina Olivia, Rugambwa, Grace Henry, Musoke, Kevin, Bardosh, Juma John, Ochieng, Fred, Ssempijja, Patrick, Kyamanywa, Gabriel, Tumwine, Khalid J., Alzahrani, Susan Christina, Welburn

“…There is a need to increase transparency and inclusive participation to address these issues before new trials of COVID-19 vaccines are initiated…”
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Grow-out of spiny lobster Panulirus sp. with high stocking density in controlled tanks by Rio Yusufi Subhan, Eddy Supriyono, Widanarni, Widanarni, Daniel Djokosetiyanto

“…The experimental spiny lobsters have the initial average weight of 130.39 ± 0.32 g and initial average total length of 140.70 ± 0.06 mm. …”
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Preoperative and intraoperative neuromonitoring and mapping techniques impact oncological and functional outcomes in supratentorial function-eloquent brain tumours: a systematic re... by Asfand Baig Mirza, Amisha Vastani, Rishabh Suvarna, Sami Rashed, Aws Al-Omari, Engelbert Mthunzi, Feras Fayez, Nicala Rampersad, Josephine Jung, Alba Díaz Baamonde, José Siado Mosquera, Ali Elhag, Francesco Marchi, Richard Gullan, Keyoumars Ashkan, Ranjeev Bhangoo, Francesco Vergani, Ana Mirallave-Pescador, José Pedro Lavrador

“…Systematic review with meta-analysis revealed a non-significantly higher average GTR rates for POM&IONM (49.13%) and POM (50.79%) compared to IONM alone (41.23%). …”
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A pharmacoinformatic approach for studying Atractylodes Lancea DC’s anticancer potential and control ROS-mediated apoptosis against prostate cancer cells by Chi-Hoon Ahn, Ji Soo Myong, Kazi Rejvee Ahmed, Md Ataur Rahman, Md. Maharub Hossain Fahim, Min Choi, Muntajin Rahman, Jinwon Choi, Kiryang Kim, Seungjoon Moon, Seungjoon Moon, Mohammed Dalli, Mohammed Dalli, Rony Abdi Syahputra, Sang-Won Shin, Abdel Halim Harrath, Moon Nyeo Park, Bonglee Kim, Hwa-Seung Yoo

“…Colony formation assays revealed a significant reduction in prolif-eration, while TUNEL and annexin V-FITC/PI staining indicated enhanced apoptosis. …”
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Global burden of metabolic dysfunction-associated steatotic liver disease, 2010 to 2021 by Gong Feng, Giovanni Targher, Christopher D. Byrne, Yusuf Yilmaz, Vincent Wai-Sun Wong, Cosmas Rinaldi Adithya Lesmana, Leon A. Adams, Jerome Boursier, George Papatheodoridis, Mohamed El-Kassas, Nahum Méndez-Sánchez, Silvia Sookoian, Laurent Castera, Wah-Kheong Chan, Feng Ye, Sombat Treeprasertsuk, Helena Cortez-Pinto, Hon Ho Yu, Won Kim, Manuel Romero-Gómez, Atsushi Nakajima, Khin Maung Win, Seung Up Kim, Adriaan G. Holleboom, Giada Sebastiani, Ponsiano Ocama, John D. Ryan, Monica Lupșor-Platon, Hasmik Ghazinyan, Mamun Al-Mahtab, Saeed Hamid, Nilanka Perera, Khalid A. Alswat, Qiuwei Pan, Michelle T. Long, Vasily Isakov, Man Mi, Marco Arrese, Arun J. Sanyal, Shiv Kumar Sarin, Nathalie Carvalho Leite, Luca Valenti, Philip N. Newsome, Hannes Hagström, Salvatore Petta, Hannele Yki-Järvinen, Jörn M. Schattenberg, Marlen I. Castellanos Fernández, Isabelle A. Leclercq, Gulnara Aghayeva, Abdel-Naser Elzouki, Ali Tumi, Ala I. Sharara, Asma Labidi, Faisal M. Sanai, Khaled Matar, Maen Al-Mattooq, Maisam Waid Akroush, Mustapha Benazzouz, Nabil Debzi, Maryam Alkhatry, Salma Barakat, Said A. Al-Busafi, John Rwegasha, Wah Yang, Agyei Adwoa, Christopher Kenneth Opio, Mohammadjavad Sotoudeheian, Yu Jun Wong, Jacob George, Ming-Hua Zheng

“…Impact and implications: This research provides a comprehensive analysis of the global burden of MASLD, highlighting its rising prevalence and incidence, particularly in countries with varying sociodemographic indices. The findings are significant for both clinicians and policymakers, as they offer critical insights into the regional disparities in MASLD burden, which can inform targeted prevention and intervention strategies. …”
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Investigation on the situation of hospital accompanying visitors and patient satisfaction under the nursing management in orthopedic wards in the post-epidemic era (后疫情时代骨科病房护理管理下住... by CHEN Liping (陈丽萍), WANG Fengmei (王凤美), LI Nannan (李南南), LI Jing (李靖)

“…Results The escort rate in June-July 2020 was significantly lower than that of the same period in 2019 (44. 57% vs 68. 26%, P=0. 001); whether there was family support during the hospitalization period did not affect patient satisfaction (F=1. 32, P=0. 182) ; Gender (t=3. 787, P<0. 001), occupation (t=2. 498, P=0. 014), and the impact of the epidemic on life (t=-2. 618, P=0. 010) are the main factors affecting satisfaction. …”
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