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  1. 79961

    First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors by Ignacio I Wistuba, Mamta Kalra, Linus Backert, Martin Wermke, Edwin R Parra, Jason John Luke, Apostolia M Tsimberidou, Sebastian Bunk, Mohammad B Hossain, Andrea Mayer-Mokler, Arun Satelli, Norbert Hilf, Steffen Walter, Cedrik M Britten, Van K Morris, Tobias A W Holderried, Winfried H Alsdorf, Katrin Wetzko, Borje S Andersson, Sandra Grund-Gröschke, Katrin Aslan, Anantha Marisetty, Swapna Satam, Jens Hukelmann, M Alper Kursunel, Karine Pozo, Andreas Acs, Melissa Baumeister, Claudia Wagner, Oliver Schoor, Ali S Mohamed, Delfi Krishna

    Published 2024-07-01
    “…Immune effector cell-associated neurotoxicity syndrome was observed in two patients and was grade 1 in both.Efficacy of IMA202 Of the 16 patients dosed, 11 (68.8%) patients had stable disease (SD) as their best overall response (Response Evaluation Criteria in Solid Tumors V.1.1). Five patients had initial tumor shrinkage in target lesions and one patient with SD experienced continued shrinkage in target lesions for 3 months in total but had to be classified as progressive disease due to progressive non-target lesions. …”
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  2. 79962

    Low light reduces saffron corm yield by inhibiting starch synthesis by Weijing Yang, Weijing Yang, Xin Li, Xin Li, Fei Chang, Fei Chang, Xue Qiu, Xulong Huang, Xulong Huang, Zhan Feng, Zhan Feng, Jie Yan, Jie Yan, Qinghua Wu, Qinghua Wu, Feiyan Wen, Feiyan Wen, Jin Pei, Jin Pei, Tao Zhou, Tao Zhou

    Published 2025-01-01
    “…Despite the marked inhibition of photosynthetic capacity, initial DW, sucrose and glucose concentrations in leaves were comparable to those under NL. …”
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  3. 79963
  4. 79964

    Identification of strengths and weaknesses of the healthcare system for persons living with rare diseases in Catalonia (Spain), and recommendations to improve its comprehensive att... by José Hernández-Rodríguez, Fernando Martínez-Valle, Xènia Acebes, Carmen Alerany, Jordi Antón, Gonzalo Calvo, Marian Corral, Jordi Cruz, M. Antònia Mangues-Bafalluy, José Mateo, Josefa Rivera, Albert Salazar, Roser Francisco, Cristina Mallol, Rita Reig-Viader, Ariadna Tigri-Santiña, Assumpta Ricart, Francesc Palau

    Published 2025-01-01
    “…Objectives The project “acERca las enfermedades raras” (in English: “bringing RDs closer”) is an initiative primary designed to generate a consensus by a multidisciplinary group of experts to detect the strengths and weaknesses in the public healthcare system concerning the comprehensive care of persons living with a RD (PLWRD) in the region of Catalonia, Spain, where a Network of Clinical Expert Units (Xarxa d’Unitats de Expertesa Clínica or XUEC) was created and is being implemented since 2015. …”
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  5. 79965

    Antenatal Care - How to ensure quality! by Lubna Ejaz

    Published 2023-09-01
    “…Pakistan Demographic Health Surveys (PDHS) have shown a significant increase in the number of women having at least one ANC contact with a skilled healthcare provider. …”
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  6. 79966

    Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population: The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Bet... by Andersson A, Bergqvist J, Schiöler L, Bossios A, Farnebo L, Holmlund T, Janson C, Keceli S, Ljunggren M, Malinovschi A, Memarian E, Nihlén U, Nilsson PM, Pesonen I, Sjöström M, Stenfors N, Sundbom F, Werner M, Torén K, Sköld M, Hellgren J

    Published 2025-02-01
    “…In the adjusted regression model, CRS was significantly associated with CAL (OR 1.40), lower airway symptoms (OR 4.59), chronic bronchitis (OR 6.48), asthma (OR 3.08), and COPD (OR 3.10).Conclusion: In this national, randomly chosen population sample of more than 30,000 middle-aged men and women, CRS is associated with CAL, lower airway symptoms, chronic bronchitis, asthma, and COPD. …”
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  7. 79967

    油脂对植物基冰淇淋乳液性质及产品品质的影响 "Effect of vegetable oil on the properties of plant-based ice cream emulsion and the quality of products" by 张贵金1,范军营2,尹永智2,逯彩云2,张晖1, 王兴国1,吴港城1 ZHANG Guijin1, FAN Junying2, YIN Yongzhi2, LU Caiyun2, ZHANG Hui1, WANG Xingguo1, WU Gangcheng1"

    Published 2025-01-01
    “…All ice cream emulsions were non-Newtonian fluids, and after the addition of modified soy protein isolate and freezing stirring, fat flocculation and partial aggregation occurred, significantly increasing the viscosity of the ice cream emulsion. …”
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  8. 79968

    Profil Kasus Tuberkulosis Paru di Instalasi Rawat Inap Paru RSUP Dr. M. Djamil Padang Periode 1 Januari 2010 - 31 Desember 2011 by Muhammad Gamal Eddin, Oea Khairsyaf, Elly Usman

    Published 2015-09-01
    “…Data analyzed resultswith Chi Square results on X 2  is 2,5  and suggested that statistically there is no relationship between gender and acid- fast bacilii examination (p &gt; 0,05). There is significant relationship between<br />smoking history and gender (X 2 = 41,6; p ≤ 0,05). …”
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  9. 79969

    The concerted actions of microRNA-29a and interferon-β modulate complete Freund's adjuvant-induced inflammatory pain by regulating the expression of type 1 interferon receptor, int... by Chien-Cheng Liu, Kuo-Chuan Hung, Yu-Yu Li, Eagle Yi-Kung Huang, Chin-Chen Chu, Lok-Hi Chow, Ping-Heng Tan

    Published 2025-03-01
    “…Results: Our results demonstrated elevated miR-29a expression (CFA 3 days: mean difference [95% confidence interval, CI]: 0.860 [0.657–1.062]; CFA 5 days: mean difference [95% CI]: 1.120 [0.917–1.322], P<0.001, n=6) and decreased IFNR1 expression (CFA 3 days: mean difference [95% CI]: −0.300 [−0.470 to −0.130]; CFA 5 days: mean difference [95% CI]: −0.330 [−0.515 to −0.145], P=0.004, n=6) from Days 3–5 post-CFA induction, with IFN-ß expression showing a significant increase from Day 2 (F [3.30, 16.5]=34.3 for factor time, P≤0.01, n=6). …”
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  10. 79970

    Association of extreme high temperature weather with non-accidental deaths among residents of Yichang city: a time-stratified case-crossover analysis by Xiaoyan MING, Yang HAN, Zhongcheng YANG, Zaoxia WANG, Shuguang XIE, Chuangang FAN

    Published 2024-10-01
    “…The P92.5-1 d, P92.5-2 d, and P92.5-3 d events had significant effects on non-accidental deaths only in residents aged 70 – 79 and ≥ 80 years, with the ORs (95%CI) of 1.17 (1.06 – 1.29) and 1.19 (1.10 – 1.29) for P92.5-1 d at lag day 0 for residents aged 70 – 79 and ≥ 80 years, followed by 1.15 (1.05 – 1.28) and 1.19 (1.10 – 1.29) for P92.5-2 d, 1.15 (1.04 – 1.29) and 1.23 (1.13 – 1.34) for P92.5-3 d. …”
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  11. 79971

    WRF-Chem simulations of snow nitrate and other physicochemical properties in northern China by X. Wang, X. Wang, T. Che, T. Che, X. Ruan, S. Yue, S. Yue, J. Wang, J. Wang, C. Zhao, C. Zhao, C. Zhao, L. Geng, L. Geng, L. Geng

    Published 2025-02-01
    “…<p>Snow is a key component of the cryosphere and has significant impacts on surface energy balance, hydrology, atmospheric circulation, etc. …”
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  12. 79972

    Stimulation of gonad maturation in mullet fish Mugil dussumieri using MT, E2, hCG, and Ovaprim hormone by Tatak Dwi Cahyono, Muhammad Zairin Junior, Odang Carman

    Published 2019-02-01
    “…Blood glucose, blood cholesterol, testosterone and estradiol hormone level in the first and second experiment showed no significant difference. The results showed that estradiol-17β and 17α-methyltestosterone induction in 9-14.7 cm body length mullet increase gonad maturity to stage II while hCG induction in 10-31 cm body length mullet increase gonad maturity to stage III.   …”
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  13. 79973

    HERA: a high-resolution pan-European hydrological reanalysis (1951–2020) by A. Tilloy, D. Paprotny, S. Grimaldi, G. Gomes, A. Bianchi, S. Lange, H. Beck, C. Mazzetti, L. Feyen

    Published 2025-01-01
    “…This has resulted in significant changes in hydrological conditions. The availability of consistent estimates of river flow at the global and continental levels is a necessity for assessing changes in the hydrological cycle. …”
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  14. 79974

    Editorial by Ann-Kristin Kölln, Antony Mason, Maria Lenk, Jörg Tremmel, Markus Rutsche

    Published 2018-12-01
    “…This is because the young have unique concerns that are significant and because their concerns might be affected by representatives’ behaviour. …”
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  15. 79975

    Navigating Ethical Dilemmas Of Generative AI In Medical Writing by Qurrat Ulain Hamdan, Waleed Umar, Mahnoor Hasan

    Published 2024-10-01
    “…Data Hallucinations The tendency of generative AI chatbots to create false information or “data hallucinations” has been a cause of grave concern in the field of academia.4 Although ChatGPT declares that “it can make mistakes and users should consider checking important information”, unregulated false results generated by chatbots can significantly degrade the integrity and authenticity of medical research, which is a field characterized by strict ethical and moral guidelines. …”
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  16. 79976

    Wetland birds of middle Vistula River during breeding season: the impact of human activities on the distribution, abundance and richness of species by Dariusz Bukaciński, Monika Bukacińska, Arkadiusz Buczyński

    Published 2020-12-01
    “…The comparison of bird richness revealed significant differences between adjoining fragments of the river (Table 3). …”
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  17. 79977

    Investigate of preoperative hope level and analysis of influencing factors in elderly patients with femoral neck fracture (老年股骨颈骨折患者术前希望水平及影响因素分析)... by ZHANG Caixia (张彩侠), LI A Min (李阿敏), PAN Rusheng (潘如胜), LI Ling (李玲), CHE Xia (车侠)

    Published 2023-09-01
    “…The results of multiple stepwise regression analysis showed that age, comorbidity index, economic status, housing status, and self-efficacy were significant predictors of the preoperative hope level of elderly patients with femoral neck fractures (p<0. 05). …”
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  18. 79978

    Journal of Health and Social Sciences: A reputable, DOAJ-indexed, free, open access journal by Francesco Chirico

    Published 2019-03-01
    “…In a time when it is difficult to give voice to voiceless people, JHSS provides room for discussions and views from researchers from poor and disadvantages countries on issues that have a significant health impact on all people, from climate change to other themes in global public health. …”
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  19. 79979

    Bio-impedancemetry an essential tool in the obesity screening of patients with chronic renal failure [La bio-impédancemétrie un outil indispensable dans le dépistage de l’obésité c... by Samia BOUDANI, Faiza ZERDOUMI, Naouel FZ. BOUMANSOUR, Abbou KADDOUS, Bachir M. GUELLIL

    Published 2024-12-01
    “…Traditional BMI measurement identifies significantly fewer CKD patients as obese, compared to nutritional endpoints based on estimating body fat percentage by impedance measurement. …”
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  20. 79980

    Investigating and Completing Khanlari’s Theory on Metrical Units by Abbas Jahed Jah

    Published 2024-12-01
    “…Khanlari is one of the scholars who has made significant efforts to address the challenges of traditional prosody. …”
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