Bullous Type 2 Lepra Reaction: A Rare and Significant Case Report by Hrithik Dakssesh Putta Nagarajan, Balakrishnan Kamaraj, Keerthivasan Selvanathan, Pruthvi Raj Kukunoor, Katta Manichandana, Katta Manideep, Biki Kumar Sah

“…ABSTRACT Bullous type 2 lepra reactions are a rare initial presentation in leprosy that can complicate the disease with vesiculo‐bullous lesions. …”
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The Evolutionary Significance of Redundancy and Variability in Phenotypic-Induction Mechanisms of Pierid Butterflies (Lepidoptera) by Arthur M. Shapiro

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Serum Interleukin-6 Expression Level and Its Clinical Significance in Patients with Dermatomyositis by Min Yang, Xiaomin Cen, Qibing Xie, Chuan Zuo, Guixiu Shi, Geng Yin

“…To analyze serum interleukin-6 (IL-6) expression level and its clinical significance in patients with dermatomyositis. Methods. …”
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Clinicopathologic Significance of CXCL12 and CXCR4 Expressions in Patients with Colorectal Cancer by Naomi Yoshuantari, Didik Setyo Heriyanto, Susanna Hilda Hutajulu, Johan Kurnianda, Ahmad Ghozali

“…Our study demonstrated that the mRNA expression of CXCL12 was significantly correlated with rectal location. CXCR4 mRNA expression was inversely correlated in tumours with a lymphatic invasion.…”
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The Clinical Significance of High Antimicrobial Resistance in Community-Acquired Urinary Tract Infections by Maria G. Zavala-Cerna, Midrori Segura-Cobos, Ricardo Gonzalez, Isidro G. Zavala-Trujillo, Silvia F. Navarro-Perez, Jose A. Rueda-Cruz, Fernando A. Satoscoy-Tovar

“…The only clinical variable with significant association to ESBL producers was the presence of comorbidities: hypertension and type 2 diabetes mellitus with an OR (95%CI) of 2.51.3−4.9p<0.01 and 2.81.2−6.7p<0.05, respectively. …”
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Feeding disruptions lead to a significant increase in disease modules in adult mice by Xiaoqin Mou, Pengxing Nie, Renrui Chen, Yang Cheng, Guang-Zhong Wang

“…Our computational analysis indicates that altered feeding schedules significantly increase disease-related modules in adult mouse livers, well before aging and disease onset. …”
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Clinical Significance and Expression of PAF and TNF-alpha in Seminal Plasma of Leukocytospermic Patients by Chaodong Liu, Hongjian Liu, Xianzhong Wang, Sun Xinbo

“…PAF concentration ( ng/mL) of leukocytospermia group was significantly lower than the normal group ( ng/mL, ) while TNF-α ( ng/mL) was significantly higher than that of normal group ( ng/mL). …”
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IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis Bacteremia by Jennifer Paterno, Alessandra Petrillo, David Samuel Dicapua Siegel, Chinwe Ogedegbe

“…This case presents a patient with bacteremia of an unusual organism with a history of monoclonal gammopathy of undetermined significance (MGUS). MGUS is typically thought to be asymptomatic until potential progression of the disease. …”
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Religious Institutions and Personal Injury Compensation Claims for Abuse: The Noteworthy Significance of Insurance by Joseph Lee

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A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial Carcinoma by Masanori Sakakima, Yoshihide Fujigaki, Hideo Yasuda, Akashi Togawa, Tomoyuki Fujikura, Atsushi Otsuka, Seiichiro Ozono, Akira Hishida

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Clinical significance of exosomal noncoding RNAs in hepatocellular carcinoma: a narrative review by Jae Sung Yoo, Min Kyu Kang

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Significance of Preoperative Systemic Immune Score for Stage I Gastric Cancer Patients by Jun Lu, Long-long Cao, Ping Li, Jian-wei Xie, Jia-bin Wang, Jian-xian Lin, Qi-yue Chen, Mi Lin, Ru-hong Tu, Chang-ming Huang, Chao-hui Zheng

“…Compared to surgery alone, AC had no significant effect on survival in both the entire cohort and the IA/IB subgroup. …”
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“Significant Negatives”: Genre and Ethics in Alice Meynell’s Familiar Essays, 1893–1909 by Rachel O’Connell

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The significance of the cestode Joyeuxiella pasqualei (cyclophyllidea: dipylidiidae) for clinical practice and the welfare of cats by Ilić Tamara, Pavlović Jelena, Jovanović Nemanja M., Stepanović Predrag, Nenadović Katarina

“…Data on the etiopathogenesis, diagnosis, and control of this tapeworm are of particular importance for inexperienced diagnosticians, who, due to insufficient knowledge about J. pasqualei parasitism, can make significant errors in clinical diagnosis. Due to its significance for clinical practice and the welfare of cats, it is necessary to include this cestode in the differential diagnosis of intestinal invagination in cats and of other carnivore cestodes, which are species from the genera Diplopylidium and Dipylidium.…”
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Clinical significance of establishing a red blood cell alloantibody detection database by XIAO Xiao, CHEN Long, ZHAO Zhenyu, HE Zhanghan, ZHOU Mengjun, TANG Jie

“…[Objective] To explore the clinical significance and application value of establishing a database for red blood cell alloantibody detection. …”
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The Clinical and Prognostic Significance of Activated AKT-mTOR Pathway in Human Astrocytomas by Elias A. El Habr, Christos Adamopoulos, Georgia Levidou, Aggeliki A. Saetta, Penelope Korkolopoulou, Christina Piperi

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Clinical and Prognostic Significance of Idiopathic Left Bundle-Branch Block in Young Adults by Pietro Delise, Luigi Rivetti, Giuseppe Poletti, Monica Centa, Giuseppe Allocca, Nadir Sitta, Arianna Cati, Giovanni Turiano, Emanuela Lanari, Paolo Zeppilli, Luigi Sciarra

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Growth Hormone-Releasing Hormone and Its Analogues: Significance for MSCs-Mediated Angiogenesis by Xiangyang Xia, Quanwei Tao, Qunchao Ma, Huiqiang Chen, Jian’an Wang, Hong Yu

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SIGNIFICANT LEVELS OF STEEL SLAG CONCRETE PRODUCED WITH VARYING WATER CEMENT RATIOS by SOLOMON IDOWU ADEDOKUN, MUKAILA ABIOLA ANIFOWOSE, SAMSON OLALEKAN ODEYEMI, JOHNSON ROTIMI OLUREMI

“… This study investigated the significance of steel slag concrete created with varying water cement ratios. …”
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The culture of ecological centers as a significant element of urban life in eco-cities by Alina Shaikhieva, Anastasya Korovina, Sergey Tkach, Maya Rusakova

“…Most users regularly come to the center, visit other eco-friendly spaces, and follow this topic on social networks. A significant proportion (47%) of respondents actively pursue environmentally friendly lifestyles, with occasional engagement in environmental organizations and infrequent financial contributions. …”
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