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1881
Exploring nurse-led cystoscopy: A systematic review of safety, efficacy, and applicability in urogynecology
Published 2024-01-01“…Further research and randomized controlled trials are needed to strengthen the evidence in this field.…”
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1882
The Impact of Polyunsaturated Fatty Acid Supplementation on Inflammatory Markers in Preterm Infants – A Literature Review
Published 2025-01-01“…Research consistently shows that PUFA supplementation lowers IL-6 levels, a cytokine considered a risk factor for sepsis in preterm infants. …”
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1883
Severe Necrotizing Adenovirus Tubulointerstitial Nephritis in a Kidney Transplant Recipient
Published 2013-01-01“…Cidofovir is considered the agent of choice for AdV infection in immunocompromised despite lack of randomized trials, and the addition of intravenous immunoglobulin may aid in resolution of infection while help prevention of rejection.…”
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1884
Tirosin Kinase Inhibitors in Chronic Graft versus Host Disease: From Bench to Bedside
Published 2011-01-01“…Translation to the clinical setting revealed that treatment with Imatinib can achieve encouraging responses in patients with autoimmune diseases and steroid-refractory cGVHD, showing a favourable toxicity profile. While the exact mechanisms leading to such efficacy are still under investigation, use of TKIs in the context of clinical trials should be promoted, aiming to evaluate the biological changes induced in vivo by TKIs and to assess the long term outcome of these patients. …”
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1885
An sveir model for assessing potential impact of an imperfect anti-SARS vaccine
Published 2006-04-01“…Owing to the recent ongoing clinical trials ofsome candidate anti-SARS vaccines, this study aims to assess, via mathematical modelling, the potential impact of a SARS vaccine,assumed to be imperfect, in curtailing future outbreaks. …”
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1886
Minimally invasive lateral, posterior, and posterolateral sacroiliac joint fusion for low back pain: a systematic review and meta-analysis
Published 2025-02-01“…Methods The PubMed, Web of Science, Embase, Cochrane Library, and ClinicalTrials.gov databases were comprehensively searched for studies up to 31 August 2024. …”
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1887
Survival Analysis of Diabetic Colorectal Cancer Patients on Metformin
Published 2023-12-01“…However, the association between cancer progression and metformin use requires further investigation, and high-powered clinical trials are needed to support these findings. …”
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1888
Application of ectoine in diseases of the skin and mucous membranes
Published 2024-06-01“…Additionally, ongoing research shows its potential in pulmonary, gastroenterological, and neurological treatment. …”
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1889
Environmental Enrichment Therapy for Autism: Outcomes with Increased Access
Published 2016-01-01“…We have previously shown in two randomized clinical trials that environmental enrichment is capable of ameliorating symptoms of autism spectrum disorder (ASD), and in the present study, we determined whether this therapy could be effective under real-world circumstances. 1,002 children were given daily Sensory Enrichment Therapy, by their parents, using personalized therapy instructions given over the Internet. …”
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1890
Deciphering the potential of plant metabolites as insecticides against melon fly (Zeugodacus cucurbitae): Exposing control alternatives to assure food security
Published 2025-01-01“…The control compound, malathion, showed lower binding affinities across all three proteins. …”
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1891
Measurement of Voice Onset Time in Maxillectomy Patients
Published 2014-01-01“…We examined voice onset time for /ka/ and /ta/ in 13 maxillectomy patients by calculating the number of valid measurements of voice onset time out of three trials for each syllable. Wilcoxon’s signed rank test showed that voice onset time measurements were more successful for /ka/ and /ta/ when a prosthesis was used (Z=−2.232, P=0.026 and Z=−2.401, P=0.016, resp.) than when a prosthesis was not used. …”
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1892
Dietary Fatty Acids and Predementia Syndromes
Published 2009-01-01“…However, recent findings from clinical trials with n-3 PUFA supplementation showed efficacy on depressive symptoms in non–Vapolipoprotein E (APOE) ε4 carriers, and on cognitive symptoms only in very mild Alzheimer's disease (AD) subgroups, MCI patients, and cognitively unimpaired non-APOE ε4 carriers. …”
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1893
Comparative analysis of Oreochromis niloticus responses to Chlorella vulgaris and Lactobacillus-fermented Azolla economic feed supplements in biofloc and green systems: An in silic...
Published 2025-03-01“…The fermentation process, involving Lactobacillus plantarum KU985433 and L. rhamnosus KU985437, enhances Azolla’s protein, phenolic, and antioxidant content while reducing carbohydrates and lipids. Comparative trials in biofloc and green water systems showed that fish fed with fermented Azolla exhibited improved growth, feed utilization, and immune response, demonstrating the potential of fermented plant-based feed as a sustainable alternative to conventional soybean meal. …”
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1894
Autologous Bone Marrow Mononuclear Cells in Ischemic Cerebrovascular Accident Paves Way for Neurorestoration: A Case Report
Published 2014-01-01“…The striking fact was that the hand functions, which are the most challenging deficits, showed significant recovery. Functional Independence Measure scores and quality of life improved. …”
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1895
The Role of Platelet Concentrates and Growth Factors in Facial Rejuvenation: A Systematic Review with Case Series
Published 2025-01-01“…The case series that goes with it shows real-world examples of how to improve skin elasticity, texture, and general facial appearance with little negative side effects. …”
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1896
The Role of Angiotensin Antagonism in Coronary Plaque Regression: Insights from the Glagovian Model
Published 2021-01-01“…Analysis from various trials utilizing ARB showed a significant plaque regression using olmesartan and telmisartan as evaluated by IVUS studies. …”
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1897
Effects of virtual reality technology on early mobility in critically ill adult patients: a systematic review and meta-analysis
Published 2025-02-01“…To evaluate the quality of the included studies, the risk of bias was assessed using the RevMan 5.4 tool.ResultsA total of 11 randomized controlled trials (RCTs) published over 10 years were included, involving 880 critically ill adult patients: 435 in the experimental group and 445 in the control group. …”
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1898
The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation
Published 2025-01-01“…However, the optimal combination of genetic modifications and their expression levels for initial clinical trials remains unclear. This study investigates the generation of TKO/hCD55/hTM/hEPCR (6GE) pigs and evaluates their compatibility with human immune and coagulation systems.MethodsThe 6GE pigs were generated through iterative genome editing and F1 generation breeding. …”
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1899
The Antiobesity Effect of GLP-1 Receptor Agonists Alone or in Combination with Metformin in Overweight /Obese Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Ana...
Published 2021-01-01“…All randomized controlled trials (RCTs) which reported the efficacy of GLP-1RAs and MET in overweight/obese PCOS patients in Medline (from Pubmed), Embase, Cochrane Central Register of Controlled Trials, Web of Science, and Scopus databases were independently searched by two reviewers. …”
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1900
CDK4/6 inhibitors promote PARP1 degradation and synergize with PARP inhibitors in non-small cell lung cancer
Published 2025-02-01“…Despite widespread deregulation of CDK4/6 activity in non-small cell lung cancer (NSCLC), clinical trials with CDK4/6 inhibitor (CDK4/6i) as a monotherapy have shown poor antitumor activity. …”
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