Mouthwash with Active Oxygen (blue®m) Reduces Postoperative Inflammation and Pain by Bruna Marca Mattei, Soraia A. W. Imanishi, Grasieli de Oliveira Ramos, Paloma Santos de Campos, Suyany Gabriely Weiss, Tatiana Miranda Deliberador

“…Then, the level of tissue inflammation was assessed, by the number of pixels, using ImageJ® software. The main results show that the blue®m mouthwash was widely accepted by patients, reducing their pain. …”
Get full text

Prefrontal cortex synchronization with the hippocampus and parietal cortex is strategy-dependent during spatial learning by Francisca García, Maria-José Torres, Lorena Chacana-Véliz, Nelson Espinosa, Wael El-Deredy, Pablo Fuentealba, Ignacio Negrón-Oyarzo

“…However, the mechanism underlying the prefrontal coordination with HPC and PPC during spatial learning is poorly understood. Here we show that during navigation trials, mice displayed two sequential behavioral stages: searching and exploration. …”
Get full text

Busting the Breast Cancer with AstraZeneca’s Gefitinib by S. Chemmalar, A. R. Intan Shameha, Che Azurahanim Che Abdullah, Nor Asma Ab Razak, Loqman Mohamad Yusof, Mokrish Ajat, Kim Wei Chan, Md Zuki Abu Bakar Zakaria

“…Unfortunately, in clinical trials, GEF did not show the outcomes expected with complete response and disease progress. …”
Get full text

Gamma delta T cells in acute myeloid leukemia: biology and emerging therapeutic strategies by Venkata Lokesh Battula, Abhishek Maiti, Adishwar Rao, Akriti Agrawal, Gautam Borthakur

“…Clinical trials leveraging γδ T cell biology have used unmodified and modified allogeneic cells as well as bispecific engagers and monoclonal antibodies. …”
Get full text

Control of Magnetic Manipulator Using Reinforcement Learning Based on Incrementally Adapted Local Linear Models by Martin Brablc, Jan Žegklitz, Robert Grepl, Robert Babuška

“…However, having a model brings benefits, mainly in terms of a reduced number of unsuccessful trials before achieving acceptable control performance. …”
Get full text

From Bench to Bedside to Bug: An Update of Clinically Relevant Advances in the Care of Persons with Helicobacter pylori Associated Diseases by N Chiba, ABR Thomson, P Sinclair

“…The role of H pylori eradication in persons with uninvestigated dyspepsia remains controversial. New clinical trials of H pylori treatment show symptom relief and improvement in the quality of life of persons with functional dyspepsia, especially in those with ulcer-like or reflux-like dyspepsia. …”
Get full text

Effect of implant abutment surface treatments on bacterial biofilm composition and structure by Eduardo Anitua, Alia Murias-Freijo, Roberto Tierno, Ricardo Tejero, Mohammad Hamdan Alkhraisat

“…Titanium nitride (TiN) coatings show antimicrobial properties. Nevertheless, there is a lack of clinical trials that assess the biofilm formation on TiN abutments in the context of clinical practice. …”
Get full text

Research on treatment-related aspects of depression from India in the preceding decade (2014–2023): An updated systematic review by Alankrit Jaiswal, S Umesh, Nishant Goyal

“…Neuro-modulation studies show promise, but larger-scale studies are needed. …”
Get full text

Natural products as anticancer agents and enhancing their efficacy by a mechanism-based precision approach by Stephen Safe

“…Many of the compounds perform poorly in clinical trials due to pharmacokinetic consideration and limited uptake (e.g., curcumin) and these are issues that can be addressed. …”
Get full text

Bolder together: conformity drives behavioral plasticity in eastern gartersnakes by Morgan Skinner, Gokulan Nagabaskaran, Tom Gantert, Noam Miller

“…Pairs were assigned based on the data from the solo trials, such that each snake was paired once with a bolder and once with a less bold partner. …”
Get full text

Adjuvant Hormonal Therapy in Postmenopausal Women with Breast Cancer: Physician’s Choices by Asim Jamal Shaikh, Shiyam Kumar, Sajjad Raza, Maria Mehboob, Osama Ishtiaq

“…Clinical trials leading to firm recommendations to set standards from which patients benefit the most are needed.…”
Get full text

Temperature and Humidity Monitoring in Hydroponic Cultivation Based on Internet of Things: Dataset Development for Smart Agriculture by Simon Prananta Barus, Jeriko Ichtus Seo

“…The results of the research show that the developed system can monitor temperature and humidity in real-time with a good level of accuracy. …”
Get full text

Employing the Oncolytic Vesicular Stomatitis Virus in Cancer Virotherapy: Resistance and Clinical Considerations by Alaa A. Abdelmageed, Stephen Dewhurst, Maureen C. Ferran

“…Several VSV-based phase I/II clinical trials show promise; however, addressing resistance and developing novel strategies to enhance therapeutic efficacy are essential for realizing the full potential of VSV oncolytic virotherapy. …”
Get full text

Cost-effectiveness analysis of romosozumab for severe postmenopausal osteoporosis at very high risk of fracture in Mexico. by Juan Pablo Diaz Martinez, Therese Aubry de Maraumont, Elly Natty Sánchez, Luis Miguel Camacho Cordero, Eric Yeh

“…<h4>Conclusions</h4>Results show that romosozumab/ denosumab produces greater health benefits at a lower total cost than teriparatide/ denosumab.…”
Get full text

Effect of Ideal Amino Acid Ratio of Arginine to Lysine on Intake, Nutrient Digestibility, Growth Performance, Antibody Titers of Newcastle Disease and Infectious Bronchitis Disease... by Wahab Liaqat, Urooj Anwar, Asfa Fatima, Azhar Rafique, Riaz Mustafa, Umar Farooq, Faisal Ramzan, Waseem Abbas, Muhammad Farooq Khalid, Muhammad Ashraf, Muhammad Riaz, Muhammad Qamar Bilal, Muhammad Aziz ur Rahman

“…The results of BWG showed that BWG was linearly increased in birds given different Arg/Lys in the grower, finisher, and overall period (<i>p</i> < 0.05). …”
Get full text

Successful Treatment of Hepatitis C with Simeprevir, Sofosbuvir, and Ribavirin in an HIV Coinfected Liver Transplant Patient with Advanced Chronic Kidney Disease by Anna Maruyama, Trana Hussaini, Nilufar Partovi, Siegfried R. Erb, Vladimir Marquez Azalgara, Nadia Zalunardo, Neora Pick, Mark Hull, Eric M. Yoshida

“…The 51-year-old male achieved SVR24, and no specific HIV-related or transplant-related adverse events were documented during the treatment period. The new DAAs show promise for HIV coinfected patients and those with severe to end-stage renal disease (ESRD); however, robust clinical trials or large cohort studies will need to be conducted to confirm the efficacy and safety of these newer agents in this setting.…”
Get full text

Exploring the role of ESR1 mutations in metastatic hormone receptor-positive breast cancer T cell immune surveillance disruption by Morgane Lopez, Laurie Spehner, Fabrice André, Julien Viot, Evan Seffar, Amélie Marguier, Elsa Curtit, Guillaume Meynard, Erion Dobi, Sylvain Ladoire, Romain Boidot, Romain Loyon, Valentin Derangere, François-Clément Bidard, Christophe Borg, Laura Mansi, Marie Kroemer

“…If ESR1 peptides-restricted lymphocytes were detectable in BC patients, ESR1 mutations promote immune escape at advanced stages. Trial registration ClinicalTrials.gov, NCT02838381. …”
Get full text

Syncopes and clinical outcome in heart failure: results from prospective clinical study data in Germany by Djawid Hashemi, Moritz Blum, Meinhard Mende, Stefan Störk, Christiane E. Angermann, Sabine Pankuweit, Elvis Tahirovic, Rolf Wachter, Burkert Pieske, Frank Edelmann, Hans‐Dirk Düngen, the German Competence Network for Heart Failure

Get full text

Analyzing the Effect of Intensive and Low-Input Agrotechnical Support for the Physiological, Phenometric, and Yield Parameters of Different Maize Hybrids Using Multivariate Statist... by A. Illes, C. Bojtor, A. Szeles, S. M. N. Mousavi, B. Toth, J. Nagy

“…Correlation and biplot analysis show that increases in the lipid peroxidation (LP) amount in the plant leaf stages cause a decrease in the oil content of the harvested yield. …”
Get full text

Acute Putrescine Supplementation with Schwann Cell Implantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injured Rats by J. Bryan Iorgulescu, Samik P. Patel, Jack Louro, Christian M. Andrade, Andre R. Sanchez, Damien D. Pearse

“…Schwann cell (SC) transplantation exhibits significant potential for spinal cord injury (SCI) repair and its use as a therapeutic modality has now progressed to clinical trials for subacute and chronic human SCI. Although SC implants provide a receptive environment for axonal regrowth and support functional recovery in a number of experimental SCI models, axonal regeneration is largely limited to local systems and the behavioral improvements are modest without additional combinatory approaches. …”
Get full text