Comparative Evaluation of the Effectiveness of Manual and Electric Toothbrushes in Blind Children: A Randomised Controlled Trial by PS Thanalakshme, R Ramesh

“…Results: Over the course of six months, the study showed that manual toothbrushes were superior to electronic toothbrushes in enhancing oral health in blind children. …”
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Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial by Xiaoyang Hong, Yongjian Guo, Wenbo Shi, Kangshun Zhu, Licong Liang, Liteng Lin, Ye Chen, Jingwen Zhou, Jingjun Huang, Jiabai Huang, Yaozhu Wu, Wensou Huang, Mingyue Cai

“…Methods This was a single-center, single-arm phase II trial recruiting patients with BCLC stage C HCC. …”
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Patient and Caregiver Perceptions of Caregiving Contributions During Cancer Clinical Trials: A Mixed‐Methods Study by Janine Cerutti, Maria C. Lent, Randall F. Holcombe, Maija Reblin

“…However, little is known regarding how caregivers support patients during cancer clinical trials. The aim of this study was to gain insight into the caregiver experience of rural and urban patients enrolled in cancer clinical trials. …”
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Vibration therapy as an intervention for trochanteric hip fractures – A randomized double-blinded, placebo-controlled trial by Ronald Man Yeung Wong, Pui Yan Wong, Chaoran Liu, Chun Sing Chui, Wing Hong Liu, Ning Tang, James Griffith, Ning Zhang, Wing Hoi Cheung

“…X-rays showed fractures healed at 12 months. LMHFV group had significantly higher quadriceps muscle strength compared to placebo group on affected leg using maximum reading (week 26: 8.8 ± 3.6 kg vs. 6.1 ± 4.1 kg; p = 0.011) and average reading (week 26: 8.0 ± 3.7 kg vs. 5.2 ± 3.3 kg; p = 0.008) amongst 3 trials. …”
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An online intervention relationship enhancement couple therapy program versus systematic desensitization on sexual performance anxiety in women undergoing infertility treatment wit... by Maryam Afzal Dehkordi, Tahmineh Farajkhoda, Mahdi Khanabadi, Farimah Shamsi

“…Materials and Methods: A parallel randomized clinical trial was conducted on 68 women with infertility in Shahrekord, Iran, in January 2022. …”
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WHEAT GENETIC RESOURCES IN KYRGYZSTAN by M. Dzhunusova, D. Ten, N. Aubekerova

“…Botanical and ecological study of material collected in different areas of Kyrgyzstan showed a broad variability of ecological and morphological forms in wheat landraces. …”
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The potential of an integrated pharmaceutical care model with telepharmacy in adherence and knowledge about pharmacological treatment in patients with mental disorders: A clinical... by Núbia Cristina Burgo Godoi de Carvalho, Ana Carolina Figueiredo Modesto, Mércia Pandolfo Provin

“…A parallel randomized clinical trial was conducted with a two-arm study in two Psychosocial Care Centers located in a state capital in Brazil. …”
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Polyethylene Glycol (PEG) Application Triggers Plant Dehydration but Does Not Accurately Simulate Drought by Gulnar Kylyshbayeva, Nazira Bishimbayeva, Sativaldy Jatayev, Serik Eliby, Yuri Shavrukov

“…In all cases, at the final stage, results of experiments in controlled conditions have to be verified in field trials with naturally occurring drought.…”
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Evaluating the Effectiveness, Safety, and Satisfaction Rates of Phenol 90%, Trichloroacetic Acid 100%, and Radiofrequency in Lateral Matricectomy for the Treatment of Ingrown Toena... by Mohammadreza Ghassemi, Zahra Keshavarz, Elham Behrangi, Afsaneh Sadeghzadeh Bazargan, Alireza Jafarzadeh, Azadeh Goodarzi

“…Phenol exhibited high success rates, minimal complications, faster healing, and excellent aesthetic outcomes. Trial Registration IRCT, IRCT20220228054152N1. Registered 03 January 2023, https://www.irct.behdasht.gov.ir/trial/65907.…”
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Can oral caffeine decrease postoperative opioid consumption following posterior spinal fusion in adolescent idiopathic scoliosis? A randomized placebo-controlled trial by Anne Stuedemann, MSN, RN, CPNP, Richard M Schwend, MD FAAP FAOA, Kenneth A. Shaw, MD, Nicolette Saddler, MSN, APRN, FNP-C, Michon Huston, PA-C, Michael Benvenuti, MD, Julia Leamon, MSN, RN, CPN, Ashley K. Sherman, MA, John Anderson, MD

“…Conclusions: Oral caffeine use resulted in an average reduction of 5 MME opioid consumption, equivalent to 5 mg of hydrocodone. While this trial was underpowered to definitively assess the outcome, oral caffeine shows potential as an adjunct medication for opioid stewardship in AIS patients. …”
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« On ne devrait exiger de personne de parler dans un micro ». Les débats autour de la présence des micros dans les prétoires dans la RFA des années 1950 by Nathalie Le Bouëdec

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The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis by Felicity S. E. Spencer, Richard J. Elsworthy, Leigh Breen, Jon R. B. Bishop, Connor Dunleavy, Sarah Aldred

“…Randomised controlled trials have investigated whether the strongest genetic risk factor for Alzheimer’s disease, APOE4, impacts the effectiveness of exercise on health. …”
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The effect of oxytocin, sublingual, and intrauterine misoprostol on blood loss in cesarean delivery: A randomized clinical trial by Mahdieh Masoumzadeh, Vahideh Rahmani, Manizheh Sayyah-Melli, Anis Sani

“…Results: The baseline characteristics showed no significant differences among the groups. …”
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Safety and Immunogenicity of Pertussis Vaccine Immunization during Pregnancy: A Meta-Analysis of Randomized Clinical Trials by Aidibai Simayi, Liguo Zhu, Hui Jin

“…The pooled OR of SAEs of women and infants did not show a statistical difference; the pooled ORs were 1.26 (95% CI: 0.78, 2.05); P=0.35) and 0.61 (95% CI: 0.37, 1.01); p=0.053), respectively. …”
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The Efficacy of Chimeric Antigen Therapy in Viral Infectious Diseases: A Systematic Review of Randomized Controlled Trials by Hossein Hatami, Elnaz Ataei, Mohammadjavad Nasiri, Hamed Ghorani

“…The primary objectives of these trials were to assess the safety and feasibility of adoptive transfer of CAR T-cells in patients with viral infections. …”
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A Randomized Controlled Clinical Trial of Lifestyle Intervention and Pioglitazone for Normalization of Glucose Status in Chinese with Prediabetes by Yingying Luo, Hongyuan Wang, Xianghai Zhou, Cuiqing Chang, Wei Chen, Xiaohui Guo, Jinkui Yang, Linong Ji, Sanjoy K. Paul

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A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma by Josefina Navarrete-Solís, Juan Pablo Castanedo-Cázares, Bertha Torres-µlvarez, Cuauhtemoc Oros-Ovalle, Cornelia Fuentes-Ahumada, Francisco Javier González, Juan David Martínez-Ramírez, Benjamin Moncada

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From Clinical Trial Evidence to Clinical Guidelines: Perspectives on REWIND from Clinicians in the Gulf and Levant Region by Talal Ashour, Sami Azar, Akram Echtay, Muhammad Farooqi, Tarek Fiad, Mohamed Hassanein, Ahmed Hassoun, Abdul Jabbar, Amin Jayyousi, Kari Ranta, Hani Sabbour, Fatih Tangi, Ibrahim Turfanda

“…Summary: Only one GLP-1 RA – dulaglutide – has demonstrated superiority versus placebo in reducing cardiovascular risk in patients with T2D with or without a history of CVD in a cardiovascular outcomes trial (CVOT). This trial – REWIND – is the only GLP-1 RA-based CVOT that recruited patients with a CVD prevalence (31%) that is similar to the estimated prevalence in primary care T2D populations in the Gulf and Levant region. …”
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Target trial emulation to evaluate the effect of immune-related adverse events on outcomes in metastatic urothelial cancer by Renate Pichler, Josef Fritz, Sarah Maier, Melanie R. Hassler, Johanna Krauter, David D`Andrea, Ekaterina Laukhtina, Kilian Gust, Keiichiro Mori, Karl H. Tully, Dora Niedersuess-Beke, Lea Korber, Jasmin Alija Spiegelberg, Thomas Bauernhofer, José D. Subiela, Roman Mayr, Andreas Kronbichler, Marco Moschini, Jeremy Teoh, Benjamin Pradere, Shahrokh F. Shariat, Hanno Ulmer, Laura S. Mertens, European Association of Urology–Young Academic Urologists (EAU-YAU): Urothelial Carcinoma Working Group

“…The aim of this study was to assess the effect of irAEs on outcomes while correcting for immortal time bias, using target trial emulation (TTE). Methods TTE was contrasted to adjusted naïve and time-updated Cox models. …”
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The Effectiveness of Fluorescent Light Energy as Adjunct Therapy in Canine Deep Pyoderma: A Randomized Clinical Trial by Andrea Marchegiani, Alessandro Fruganti, Andrea Spaterna, Matteo Cerquetella, Adolfo M. Tambella, Susan Paterson

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