The spatially informed mFISHseq assay resolves biomarker discordance and predicts treatment response in breast cancer by Evan D. Paul, Barbora Huraiová, Natália Valková, Natalia Matyasovska, Daniela Gábrišová, Soňa Gubová, Helena Ignačáková, Tomáš Ondris, Michal Gala, Liliane Barroso, Silvia Bendíková, Jarmila Bíla, Katarína Buranovská, Diana Drobná, Zuzana Krchňáková, Maryna Kryvokhyzha, Daniel Lovíšek, Viktoriia Mamoilyk, Veronika Mancikova, Nina Vojtaššáková, Michaela Ristová, Iñaki Comino-Méndez, Igor Andrašina, Pavel Morozov, Thomas Tuschl, Fresia Pareja, Jakob N. Kather, Pavol Čekan

“…This technique ensures tumor purity, unbiased whole transcriptome profiling, and explicitly quantifies intratumoral heterogeneity. Here we show mFISHseq has 93% accuracy compared to immunohistochemistry. …”
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Benefits, limits, and risks of ChatGPT in medicine by Jonathan A. Tangsrivimol, Jonathan A. Tangsrivimol, Erfan Darzidehkalani, Hafeez Ul Hassan Virk, Zhen Wang, Zhen Wang, Jan Egger, Michelle Wang, Sean Hacking, Benjamin S. Glicksberg, Markus Strauss, Markus Strauss, Chayakrit Krittanawong, Chayakrit Krittanawong

“…ChatGPT represents a transformative technology in healthcare, with demonstrated impacts across clinical practice, medical education, and research. Studies show significant efficiency gains, including 70% reduction in administrative time for discharge summaries and achievement of medical professional-level performance on standardized tests (60% accuracy on USMLE, 78.2% on PubMedQA). …”
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Perfusion mode as a factor of appearance of cognitive dysfunction in patients after on-pump coronary artery bypass grafting by S.M. Sudakevych, О.А. Loskutov, І.P. Shlapak, V.V. Babenko, B.М. Todurov

“…The test battery consisted of a Mini Mental State Examination, a Grooved Pagboard and a Trial Making Test Part A. Results. The results of the Trial Making Test Part A tests showed that patients of the 1st group were spending 21.6 (18.4, 32.1) % more time for testing (as compared to the initial time) on day 7 and by 7.9 (5.3, 15.6) % more time in 3 months at that time, as in the second group, this indicator was 13.8 (11, 16.5) % on day 7 and 3.3 (0, 5.7) % after 3 months. …”
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Public health care system, a quasi-experimental study: Acceptance and attitude to implicate clinical services by Gillani Syed Wasif, Abdul Mohi Iqbal Mohammad

“…A 3-phase objective structured clinical examination (OSCE) design was utilized for evaluation of acceptance and attitude of pharmacy students towards clinical pharmacy services. The pre-OSCE survey showed increased disagreement with the role of clinical pharmacists, compared to a significant positive shift in attitude towards their services in the healthcare team after 6 months of the trial. …”
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RESEARCH ON COOLING PERFORMANCE OF HIGH POWER POWER BATTERY PACK BASED ON MULTI-OBJECTIVE GENETIC ALGORITHM by TONG GaoPeng, WANG ZhiFeng

“…The optimization results showed that the maximum temperature decreased by 9.7%, the maximum temperature difference decreased by 12.5%, and the cell spacing decreased by 7.1%. …”
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Effect of Soil Amendments to Survival Rate of Bidara Laut (Strychnos lucida R.Br.) in the Mount Tunak Natural Tourism Park, West Nusa Tenggara by Ali Setyayudi, Ryke Nandini, Krisnawati Krisnawati

“…Each block included ten replication plants (in total 750 plants), and the trial lasted 19 months. The results showed an insignificant growth increase after 19 months of planting in all treatments. …”
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Bayesian Estimation of Ammunition Demand Based on Multinomial Distribution by Kang Li, Xian-ming Shi, Juan Li, Mei Zhao, Chunhua Zeng

“…In view of the small sample size of combat ammunition trial data and the difficulty of forecasting the demand for combat ammunition, a Bayesian inference method based on multinomial distribution is proposed. …”
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Clinical Efficacy of Bhramari Pranayama on Serum Cortisol in Anidra (insomnia) by Nisha Garg, Srikanta Kumar Panda

“…Statistical analysis using an unpaired t-test showed significant differences between both groups (P < 0.05). …”
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Treatment of posterolateral tibial plateau fractures through the articular line approach by Jinxi Hu, Hexin Zhang

“…Postoperative assessments showed normal knee extension, with patients returning to pre-injury work levels. …”
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Predicted missing information biases ensemble perception of temporally ordered facial expressions by Jiahao Lu, Jun Wang

“…In Experiment 1a and 1b, we manipulated the amount of prior information from local regularity by varying the position of the missing expression in the temporal sequence (1a: Neutral to Disgust and/or Disgust to Neutral,1b: Neutral to Happy and/or Happy to Neutral) within a trial. Results showed that ensemble estimates were towards the mean of expressions including both the presented and the missing faces, only when sufficient predictability (e.g. a missing expression in the late position) informed by local regularity. …”
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Time is Confidence: Monetary Incentives Metacognitive Profile on Duration Judgment by Mitra Taghizadeh Sarabi, Eckart Zimmermann

“…To test this question, we collected trial-based confidence reports in a task where participants made categorical decisions about probe durations relative to the reference duration. …”
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The Shoot Growth of Several Selected Clones of Teak after Coppicing in the Nursery by Hamdan Adma Adinugraha, Tri Maria Hasnah, Waris Waris

“…Teak hedge garden was established to multiply several selected clones of teak from clonal test trial. It was usually established on a certain arable land. …”
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White Spot Disease in Black Tiger Shrimp (Penaeus Monodon Fab.) : Infection of White Spot Virus at 20, 100 and 200 uG/Ml by Dipping Method within 120 Minutes Exposure Time by M. Alifuddin, D. Dana, M. Eidman, M.B. Malole, F.H. Pasaribu

“… An infection trial of white spot disease on tiger shrimp was conducted by water borne inoculation with the different of  viral concentration. …”
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Laser Assisted New Attachment Procedure: An Adjunct to Scaling and Root Planing in Moderate to Deep Periodontal Pockets Treatment by Arif Siddiqui, Zoya Chowdhary, Anamika, Disha Gupta, Monika Loitongbam, Vikas Singh

“…Introduction: In order to assess the effectiveness of a laser-assisted new attachment method (LANAP) employing a diode in treating moderate to deep periodontal pockets, a split-mouth randomized controlled trial was carried out. Methods: Ten participants, aged 18–65, with moderate to deep periodontal pockets were included in the research. …”
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Short-Acting Beta-Agonist Research: A Perspective by Malcolm R Sears

“…A randomized controlled trial of regular inhaled fenoterol versus as-needed bronchodilator use showed worsened asthma control during regular treatment despite concomitant use of inhaled corticosteroids. …”
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Projeto de Turismo de Base Comunitária Tartaruga Imbricata, Brasil / Guiana Francesa by Nádia Bandeira Sacenco Kornijezuk

“…The experience included: catraias (little motor boats) crossings, passages in inflatable boats, truck trips on dangerous highways, and the best: long stretches of river aboard the Peixe-boi boat, thatwould become our hotel, transportation, cafeteria and the stage of the intense “se découvrir en Terres Inconnues” seminar. In general, the trial showed positive results. I concluded that community-based tourism, as it was held in Cabo Orange National Park, has two main effects: the unique experience of living with coastal communities and the deepening of relations between the national park and its surroundings. …”
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Development of UHPC Mixtures Utilizing Natural and Industrial Waste Materials as Partial Replacements of Silica Fume and Sand by Shamsad Ahmad, Ibrahim Hakeem, Mohammed Maslehuddin

“…A base mixture of UHPC without replacement of silica fume or sand was selected and a total of 24 trial mixtures of UHPC were prepared using different percentages of NP, FA, LSP, CKD, and PSS, partially replacing the silica fume and sand. …”
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The neuroscientific basis of flow: Learning progress guides task engagement and cognitive control by Hairong Lu, Dimitri Van der Linden, Arnold B. Bakker

“…Building on computational theories of intrinsic motivation, this study examines how learning progress predicts engagement and directs cognitive control. Results showed that task engagement, indicated by feelings of flow and low distractibility, is a function of learning progress. …”
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Application of a 3D Fusion Model to Evaluate the Efficacy of Clear Aligner Therapy in Malocclusion Patients: Prospective Observational Study by Chaofeng Liu, Yan Liu, Chunyan Yi, Tao Xie, Jingjun Tian, Peishen Deng, Changyu Liu, Yan Shan, Hangyu Dong, Yanhua Xu

“…The construction and application of a 3D fusion model in clear aligner orthodontics represent a significant leap forward, offering substantial clinical benefits while establishing a new standard for precision, personalization, and evidence-based treatment planning in the field. Trial RegistrationChinese Clinical Trial Registry ChiCTR2400094304, https://www.chictr.org.cn/hvshowproject.html?…”
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Utilization of donor CLL-1 CAR-T cells for the treatment of relapsed of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation by Meng Zhang, Meng Zhang, Xiaomei Zhang, Xiaomei Zhang, Jiaxi Wang, Wenyi Lu, Xia Xiao, Hairong Lyu, Xiaoyuan He, Yedi Pu, Juanxia Meng, Cuicui Lyu, Xinping Cao, Mingfeng Zhao, Mingfeng Zhao

“…And adjusting the ratio of CD4+ CAR-T cells and CD8+ CAR-T cells prior to infusion may help mitigate CAR-T cell-related side effects.Clinical trial registrationhttps://www.chictr.org.cn/, identifier ChiCTR2000041054.…”
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