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    Navigating large-volume subcutaneous injections of biopharmaceuticals: a systematic review of clinical pipelines and approved products by Philip Green, Andreas Schneider, Jakob Lange

    Published 2024-12-01
    “…In contrast, non-cancer LVSCs (n = 107), which are typically self-administered monthly, show more significant dosing variability, with < 5.0 mL being the predominant volume range. …”
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  4. 1204

    Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light Spectroscopy by Barbara Marschollek, Mathias Nelle, Martin Wolf, Stephan Baumgartner, Peter Heusser, Ursula Wolf

    Published 2010-01-01
    “…Clinical trials have reported statistically significant and clinically relevant effects of homeopathic preparations. …”
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  5. 1205

    Fortified Iodine Milk Improves Iodine Status and Cognitive Abilities in Schoolchildren Aged 7–9 Years Living in a Rural Mountainous Area of Morocco by Fatima Ezzahra Zahrou, Mehdi Azlaf, Imane El Menchawy, Mohamed El Mzibri, Khalid El Kari, Asmaa El Hamdouchi, Fatima-Zahra Mouzouni, Amina Barkat, Hassan Aguenaou

    Published 2016-01-01
    “…In a double-blind controlled trial conducted on schoolchildren, children were divided into two groups to receive fortified milk (30% of cover of RDI iodine) or nonfortified milk for 9 months. …”
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  6. 1206

    Endothelial Progenitor Cells for Diagnosis and Prognosis in Cardiovascular Disease by Caterina Oriana Aragona, Egidio Imbalzano, Federica Mamone, Valentina Cairo, Alberto Lo Gullo, Angela D’Ascola, Maria Adriana Sardo, Michele Scuruchi, Giorgio Basile, Antonino Saitta, Giuseppe Mandraffino

    Published 2016-01-01
    “…Due to their capability of proliferation, circulation, and the development of functional progeny, great interest has been directed to therapeutic use of progenitor cells in atherosclerotic diseases. This trial is registered with registration number: Prospero CRD42015023717.…”
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  7. 1207

    Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients... by Ken Sugimoto, Tomohiro Katsuya, Kei Kamide, Tomomi Fujisawa, Izumi Shimaoka, Mitsuru Ohishi, Ryuichi Morishita, Toshio Ogihara, Hiromi Rakugi

    Published 2010-01-01
    “…We performed a prospective study to examine the genetic effect on the response to a calcium (Ca) channel blocker, azelnidipine and an ACE inhibitor, temocapril treatment in patients with hypertension, as a part of the prior clinical trial, the Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study (ATTEST). …”
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  8. 1208
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  10. 1210

    Extensive Use of Interventional Therapies Improves Survival in Unresectable or Recurrent Intrahepatic Cholangiocarcinoma by Ricarda Seidensticker, Max Seidensticker, Kathleen Doegen, Konrad Mohnike, Kerstin Schütte, Patrick Stübs, Erika Kettner, Maciej Pech, Holger Amthauer, Jens Ricke

    Published 2016-01-01
    “…Median survival was 33.1 months from time of diagnosis and 16.0 months from first therapy. UICC stage analysis showed a median survival of 15.9 months for stage I, 9 months for IIIa, 18.4 months for IIIc, and 13 months for IV. …”
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  11. 1211
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    Effect of sowing date and irrigation norms on yield components of different sweet corn hybrids by Tupajić Ivan, Moravčević Đorđe, Ćosić Marija, Stojiljković Jelena, Stevanović Dragana, Sudimac Maja, Luković Kristina, Šević Biljana

    Published 2024-01-01
    “…This experimental trial was conducted during the 2022/23 growing season in the Bresje village area near Velika Plana, on anthropogenized soil, using a randomized block design with four replications. …”
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  14. 1214

    Volatile organic compounds of hoary stock are responsible for suppressing downy mildew of grape in an intercropping system by Weiping Deng, Fei Du, Rongliang Yang, Hanyang Yao, Min Yang, Xinyue Mei, Chen Ye, Su Li, Yixiang Liu, Huichuan Huang, Shusheng Zhu

    Published 2025-01-01
    “…The field results showed that intercropping effectively suppressed grape downy mildew, particularly during the blooming stage of hoary stock. …”
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  15. 1215

    Amorphous silica reduces N2O emissions from arable land at the field plot scale by Mathias Hoffmann, Oscar Rodrigo Monzon Diaz, Isabel Zentgraf, Wael Al-Hamwi, Maren Dubbert, Mathias Stein, Maire Holz, Jörg Schaller, Jörg Schaller

    Published 2025-01-01
    “…Both factors are known to directly and indirectly affect N2O emissions from agroecosystems.MethodsIn this study we conducted a field plot trial on arable soil depleted in ASi and fertilized this soil to its pre-agricultural ASi level.ResultsOur data clearly shows that increasing soil ASi to a pre-agricultural level decreased seasonal N2O emissions by ∼30%.DiscussionThis reduction of N2O emissions due to ASi might be of global relevance as agricultural practice has reduced the ASi content in agricultural soils. …”
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  16. 1216

    Optimizing the frequency of question items for bird species in quiz-style online training by Yui Ogawa, Keita Fukasawa, Akira Yoshioka, Nao Kumada, Akio Takenaka, Takashi Kamijo

    Published 2025-03-01
    “…We then evaluate the effectiveness of the algorithms in a randomized controlled trial, based on test scores and questionnaire responses. …”
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  17. 1217

    Real-World Data for Lenvatinib in Radioiodine-Refractory Differentiated Thyroid Cancer (RELEVANT): A Retrospective Multicentric Analysis of Clinical Practice in Austria by G. Rendl, B. Sipos, A. Becherer, S. Sorko, C. Trummer, M. Raderer, W. Hitzl, M. Ardelt, H. J. Gallowitsch, C. Pirich

    Published 2020-01-01
    “…The effects were comparable to the registration trial, although patients had a higher median age and, more commonly, dose reductions.…”
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  18. 1218

    Electrogenic amino acid transport in the intestine of sea bream (Sparus aurata): From functional characterization to physiological effects of Lysophospholipids in aquafeeds by Rocio Robles-Arozarena, Juan Antonio Martos-Sitcha, Laura Bermúdez, Waldo Nuez-Ortín, Juan Fuentes

    Published 2025-03-01
    “…The LPL-inclusion was without effects on fish growth in a short-term feeding trial, although there was a significant improvement of hepatosomatic and viscerosomatic indices. …”
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  19. 1219

    Disparities in response to mRNA SARS-CoV-2 vaccines according to sex and age: A systematic review by Michelle Bachmann, Nejla Gültekin, Zeno Stanga, Jan S. Fehr, Ismail I. Ülgür, Patricia Schlagenhauf

    Published 2025-02-01
    “…Results: After screening, 15 studies satisfied the inclusion criteria. The results showed that the COVID-19 mRNA vaccines typically elicit robust immune responses, and that younger people have higher antibody levels. …”
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  20. 1220

    Proinflammatory Cytokine IL-6 and JAK-STAT Signaling Pathway in Myeloproliferative Neoplasms by Vladan P. Čokić, Olivera Mitrović-Ajtić, Bojana B. Beleslin-Čokić, Dragana Marković, Marijana Buač, Miloš Diklić, Nada Kraguljac-Kurtović, Svetozar Damjanović, Pavle Milenković, Mirjana Gotić, Puri K. Raj

    Published 2015-01-01
    “…The recent JAK1/2 inhibitor trial in myeloproliferative neoplasms (MPNs) showed that reducing inflammation can be more beneficial than targeting gene mutants. …”
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