A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma by Josefina Navarrete-Solís, Juan Pablo Castanedo-Cázares, Bertha Torres-µlvarez, Cuauhtemoc Oros-Ovalle, Cornelia Fuentes-Ahumada, Francisco Javier González, Juan David Martínez-Ramírez, Benjamin Moncada

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Target trial emulation to evaluate the effect of immune-related adverse events on outcomes in metastatic urothelial cancer by Renate Pichler, Josef Fritz, Sarah Maier, Melanie R. Hassler, Johanna Krauter, David D`Andrea, Ekaterina Laukhtina, Kilian Gust, Keiichiro Mori, Karl H. Tully, Dora Niedersuess-Beke, Lea Korber, Jasmin Alija Spiegelberg, Thomas Bauernhofer, José D. Subiela, Roman Mayr, Andreas Kronbichler, Marco Moschini, Jeremy Teoh, Benjamin Pradere, Shahrokh F. Shariat, Hanno Ulmer, Laura S. Mertens, European Association of Urology–Young Academic Urologists (EAU-YAU): Urothelial Carcinoma Working Group

“…The aim of this study was to assess the effect of irAEs on outcomes while correcting for immortal time bias, using target trial emulation (TTE). Methods TTE was contrasted to adjusted naïve and time-updated Cox models. …”
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The Effectiveness of Fluorescent Light Energy as Adjunct Therapy in Canine Deep Pyoderma: A Randomized Clinical Trial by Andrea Marchegiani, Alessandro Fruganti, Andrea Spaterna, Matteo Cerquetella, Adolfo M. Tambella, Susan Paterson

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Satisfactory Evaluation of Call Service Using AI After Ureteral Stent Insertion: Randomized Controlled Trial by Ukrae Cho, Yong Nam Gwon, Seung Ryong Chong, Ji Yeon Han, Do Kyung Kim, Seung Whan Doo, Won Jae Yang, Kyeongmin Kim, Sung Ryul Shim, Jaehun Jung, Jae Heon Kim

“…Otherwise, most of the other variables showed no significant differences (P.>05). …”
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Kidney REPLACEment therapies in patients with acute kidney injury and RHABDOmyolysis (ReplaceRhabdo): a pilot trial by Lorenz Weidhase, Antonia Borrmann, Anja Willenberg, Meinhard Mende, Christina Scharf-Janßen, Sirak Petros, Jonathan de Fallois

“…Conclusions All tested modes showed an effective myoglobin elimination capacity. …”
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Gut microbiota differences between sports and non-sports major students: a population-controlled trial by Benlong Ma, Yifang Zhang, Wenbo Yuan, Nan Hu, Shanshan Li

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Laparoscopic suture repair for perforated peptic ulcer disease: a meta-review and trial sequential analysis by S. I. Panin, T. V. Nechay, I. V. Sazhin, K. Yu. Melnikov-Makarchuk, A. V. Sazhin, A. V. Puzikova, A. N. Akinchits, A. V. Bykov

“…Meta-epidemiology, as a form of evidence synthesis, allows for the pooling of data and assessment of the diversity present in multiple and overlapping SRs.Aim of the researchThis study aimed to summarize evidence from systematic reviews of randomized controlled trials and reanalyze outcome data on laparoscopic suture repair of perforated peptic ulcers using trial sequential analysis (TSA).Materials and methodsThe Cochrane Library, PubMed, Embase, CINAHL, eLibrary, and ClinicalTrials.gov were searched before 1 June 2024. …”
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Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial by Judith Bellapart, Vinesh Appadurai, Melissa Lassig-Smith, Janine Stuart, Christopher Zappala, Rob Boots

“…Single center, randomized control trial with consecutive recruitment over 5 years. …”
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Assessing the comparative effectiveness of ECHO and coaching implementation strategies in a jail/provider MOUD implementation trial by Todd Molfenter, Jessica Vechinski, Jee-Seon Kim, Jingru Zhang, Lionel Meng, Jessica Tveit, Lynn Madden, Faye S. Taxman

“…Trial registration number: NCT04363320. Date of registration: 2020–07-30. …”
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Game theory and weight loss: Harmonic evidence from randomized controlled trials in Appalachia, KY and Jordan. by Daniel E Zoughbie, Dillon Huddleston, Eric L Ding

“…For the first time, we are showing increased cooperative behaviors causally associated with these trials.…”
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Multicenter Randomized Clinical Trial of Brief Psychotherapy versus Usual Treatment for Common Mental Disorders in Adults by Marco A. Luengo-Castro, Javier Fernández-Méndez, José M. García-Montes, Pedro J. Caunedo-Riesco, Juan M. García-Haro, Begoña Braña-Menéndez, Dolores González-Díaz, Andrés Cabero-Álvarez, Marcelino Cuesta-Izquierdo

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Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover Trial by Anuwat Amatachaya, Narong Auvichayapat, Niramol Patjanasoontorn, Chanyut Suphakunpinyo, Niran Ngernyam, Benchaporn Aree-uea, Keattichai Keeratitanont, Paradee Auvichayapat

“…Measures of CARS, ATEC, and CGAS were administered before treatment and at 7 days posttreatment. The result showed statistical decrease in CARS score (P<0.001). …”
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Efficacy and Adverse Effects of Atropine for Myopia Control in Children: A Meta-Analysis of Randomised Controlled Trials by ChunWen Chen, JingYan Yao

“…We selected randomised controlled trials (RCTs) that evaluated the efficacy of atropine for controlling myopia progression in children. …”
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From Lab to Clinic: Effect of Academia–Industry Collaboration Characteristics on Oncology Phase 1 Trial Entry by Wonseok Yang, Sang‐Won Lee

“…ABSTRACT This study investigated the success rate of Phase 1 clinical trial entry and the factors influencing it in oncology projects involving academia–industry collaboration during the discovery and preclinical stages. …”
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Autologous Stem Cell Therapy in Critical Limb Ischemia: A Meta-Analysis of Randomized Controlled Trials by Baocheng Xie, Houlong Luo, Yusheng Zhang, Qinghui Wang, Chenhui Zhou, Daohua Xu

“…A systematic literature search was performed in the SinoMed, PubMed, Embase, ClinicalTrials.gov, and Cochrane Controlled Trials Register databases from building database to January 2018. …”
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A Randomized Clinical Trial of Nutrition Education for Improvement of Diet Quality and Inflammation in Iranian Obese Women by Majid Mohammadshahi, Fatemeh Haidari, Majid Karandish, Sara Ebrahimi, Mohammad-Hosein Haghighizadeh

“…Sixty obese women voluntarily participated in this randomized clinical trial and were randomly assigned to intervention or control group (n=30). …”
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Effect of application of the thoracoabdominal rebalancing (TAR) method in moderate premature children: randomized and controlled clinical trial by Jaqueline Lomônaco Lemos, Denise Iunes, Aline Roberta Danaga, Carmélia Rocha, Juliana Bassalobre Carvalho Borges

“…Methods: This randomized clinical trial was conducted in a neonatal intensive care unit. …”
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The use of dance to improve the health and wellbeing of older adults: A global scoping review of research trials. by Martha Waugh, Gregory Youdan, Courtney Casale, Rachel Balaban, Emily S Cross, Dafna Merom

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Impact of telephone follow-up on COPD outcomes in pulmonary rehabilitation patients: A randomized clinical trial by Stefanie Tonguino Rosero, Juan Carlos Ávila Valencia, Jhonatan Betancourt Peña

“… # Methods Double-blind randomized controlled clinical trial in patients with COPD in a PR program in Cali-Colombia, allocation by randomization tables. …”
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Methodological insights into intervention and outcomes in randomised controlled trials of herbal medicine for obesity: a scoping review by Janice Sue Wen Chan, Mei Siu Lau, Siti Hajar Muhamad Rosli, Siti Khadijah Mustapha Kamal, Wan Nurul Nadia Wan Seman, Nurul Hidayah Ali, Terence Yew Chin Tan, Ida Farah Ahmad, Puspawathy Krishnan, Marisa Khatijah Borhan, Ami Fazlin Syed Mohamed, Xin Yi Lim

“…Background: With rising obesity rates worldwide, clinical trials focused on identifying effective treatments are increasing. …”
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