Beneficial Effects of Ursodeoxycholic Acid on Metabolic Parameters and Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind, Placebo-Controlled Cli... by Biljana Lakić, Ranko Škrbić, Snežana Uletilović, Nebojša Mandić-Kovačević, Milkica Grabež, Mirna Popović Šarić, Miloš P. Stojiljković, Ivan Soldatović, Zorica Janjetović, Anastasija Stokanović, Nataša Stojaković, Momir Mikov

“…The eight-week UDCA administration showed beneficial effects on metabolic and oxidative stress parameters in patients with T2DM. …”
Get full text

Comparing simple and functional jejunal interposition with preserved duodenal passage after total gastrectomy by Xue-Lu Zhou, Yan-Qing Deng, Pei-Jie Zhang, Hai Huang, Huan-Bin Zhang, Hong-Shuai Li, You-Hua Wang, Jian-Hua Luo

“…Objective: This prospective randomized controlled trial aimed to compare the effectiveness of functional jejunal interposition (FJI) and simple jejunal interposition (SJI) as reconstruction methods following total gastrectomy for gastric cancer. …”
Get full text

Screening Selected Solanum Plants as Potential Rootstocks for the Management of Root-Knot Nematodes (Meloidogyne incognita) by Benjamin A. Okorley, Charles Agyeman, Naalamle Amissah, Seloame T. Nyaku

“…-infested field in a two-year trial (2015–2016), to identify RKN-resistant rootstock(s), which can be utilized in tomato grafting as a management measure against these nematodes. …”
Get full text

Effect over coagulation and fibrinolysis parameters of a prolonged release 24 + 4 daily use regime contraceptive formulation containing 2 mg dienogest/0.02 mg ethinylestradiol... by Pedro-Antonio Regidor, Alicyoy Angulo, Enrico Colli

“…All other parameters showed no significant differences before and after the treatment for both groups.Conclusion The COC 2 mg DNG/0.02 mg EE was not associated with any meaningful changes in the analyzed coagulation and fibrinolytic parameters indicating that a prolonged release formulation does not impact on these factors.Clinical trial registry EudraCT: 2019-0018-77-97…”
Get full text

Study on the Analgesic Efficacy of Femoral Nerve Block for Post-Hip Arthroscopy Pain by Mengwen Xue, Li Zhang, Ruiping Bai, Rui An, Jiarui Li, Xin Shen

“…However, it requires specialized equipment and technical support and carries a certain risk of puncture. Trial Registration Chinese Clinical Trials Registry (ChiCTR2400091579).…”
Get full text

Effect and safety of ethanolamine oleate in sclerotherapy in patients with difficult-to-resect venous malformations: A multicenter, single-arm study. by Mine Ozaki, Tadashi Nomura, Keigo Osuga, Masakazu Kurita, Ayato Hayashi, Shunsuke Yuzuriha, Noriko Aramaki-Hattori, Makoto Hikosaka, Taiki Nozaki, Michio Ozeki, Junko Ochi, Shimpei Akiyama, Yasumasa Kakei, Keiko Miyakoda, Naoko Kashiwagi, Takahiro Yasuda, Yuki Iwashina, Tsuyoshi Kaneko, Kiyoko Kamibeppu, Takafumi Soejima, Kiyonori Harii

“…<h4>Design and setting</h4>This investigator-initiated clinical trial employed a multicenter, single-arm design and was conducted in Japan.…”
Get full text

Venetoclax added to CLAG regimen might improve the outcome of patients with relapsed/refractory acute myeloid leukemia by Yu Zhang, Zhao Yin, Zurong Yao, Dan Xu, Xuejie Jiang, Xiaqi Nie, Dandan Chen, Hongsheng Zhou, Pengcheng Shi, Hui Liu, Qifa Liu, Guopan Yu

“…Although not statistically significant, patients in the CLAG + Ven group showed a potential survival advantage compared to the CLAG group. …”
Get full text

Long-term safety of dexamethasone sodium phosphate encapsulated in autologous erythrocytes in pediatric patients with ataxia telangiectasia by Mary Kay Koenig, Vincenzo Leuzzi, Riadh Gouider, Riadh Gouider, Eppie M. Yiu, Eppie M. Yiu, Barbara Pietrucha, Asbjørg Stray-Pedersen, Susan L. Perlman, Steve Wu, Trudy Burgers, Rupam Borgohain, Rukmini Mridula Kandadai, Isabelle Meyts, Giorgia Bucciol, Anaita Udwadia-Hegde, Ravi Yadav, Donna Roberts, Aaron Dane, Maureen Roden, Dirk Thye, Biljana Horn, Howard M. Lederman, William P. Whitehouse

“…The mean bone mineral density (BMD) z-score showed a decline of 0.4 points over the 24 months of treatment. …”
Get full text

A network-based analysis anticipates time to recovery from major depression revealing a plasticity by context interplay by Claudia Delli Colli, Aurelia Viglione, Silvia Poggini, Francesca Cirulli, Flavia Chiarotti, Alessandro Giuliani, Igor Branchi

“…In this study, we aimed to show that measuring patients’ plasticity – that is the susceptibility to modify the mental state – identifies at baseline who will recover, anticipating the time to transition to wellbeing. …”
Get full text

Analysis and Engineering Practice of Factors Affecting Top-Coal Recovery in a Large Dip Coal Seam by Xinglong Huang, Ying Chen, Yang Li, Fengshuo Jia, Shengjian Liang, Xiufeng Zhang, Yang Chen, Qianjia Hui, Zhiwen Wang, Zhaoju Zhang, Zhijie Zhu, Dequan Sun

“…The influences of the coal seam’s dip angle, mining direction, and coal caving mode and interval on the recovery were analyzed using PFC2D simulation. Field trials were also carried out. The results of the numerical calculations show that the recovery of top coal is clearly affected by the dip angle, with recovery decreasing as the dip angle is increased. …”
Get full text

The Effect of Therapeutic Blockades of Dust Particles-Induced Ca2+ Signaling and Proinflammatory Cytokine IL-8 in Human Bronchial Epithelial Cells by Ju Hee Yoon, Sung Hwan Jeong, Jeong Hee Hong

“…PM10-mediated Ca2+ signal and IL-8 expression were attenuated by several pharmacological blockades such as antioxidants, IP3-PLC blockers, and TRPM2 inhibitors. Our results show that blockades of PLC or TRPM2 reduced both of PM10-mediated Ca2+ signal and IL-8 expression, suggesting that treatment with these blockades should be considered for potential therapeutic trials in pulmonary epithelium for inflammation caused by environmental events such as seasonal dust storm.…”
Get full text

The effect of allergic rhinitis treatment on asthma control: a systematic review by Ellen Tameeris, Arthur M. Bohnen, Patrick J. E. Bindels, Gijs Elshout

“…Quality of life (QoL) showed a significant and clinically relevant improvement in five studies. …”
Get full text

Effectiveness of the Laser Application in Temporomandibular Joint Disorder: A Systematic Review of 1172 Patients by Abdalwhab Zwiri, Manal Ahmad Alrawashdeh, Mohammad Khan, Wan Muhamad Amir W. Ahmad, Nur Karyatee Kassim, Jawaad Ahmed Asif, Khoo Suan Phaik, Adam Husein, Zuryati Ab-Ghani

“…Therefore, laser therapy can be recommended for the TMD patients’ better outcome. This trial is registered with PROSPERO (CRD42020177562).…”
Get full text

Estimating Complex Signals With a Fuzzy-Enhanced Kalman Filter: A Note on &#x201C;the Output Regulation and the Kalman Filter as the Signal Generator&#x201D; by Jesus Alberto Meda-Campana, Juan Carlos Garcia-Hernandez, Rodolfo Daniel Velazquez-Sanchez, Luis Alberto Paramo-Carranza, Tonatiuh Hernandez-Cortes, Ricardo Tapia-Herrera

“…This typically requires a trial-and-error process, often resulting in an excessively large filter dimension that complicates the method&#x2019;s practical application. …”
Get full text

Autologous CIK Cell Immunotherapy in Patients with Renal Cell Carcinoma after Radical Nephrectomy by Yajing Zhang, Jin Wang, Yao Wang, Xue-Chun Lu, Hui Fan, Yang Liu, Yan Zhang, Kai-Chao Feng, Wen-Ying Zhang, Mei-Xia Chen, Xiaobing Fu, Wei-Dong Han

“…This trial is registered with Clinicaltrials.gov NCT01799083.…”
Get full text

Challenges of Assessing Maltreated Children Coming into Foster Care by Rachel Pritchett, Harriet Hockaday, Beatrice Anderson, Claire Davidson, Christopher Gillberg, Helen Minnis

“…The child’s engagement in the cognitive task showed associations with the child’s attainment on the task. …”
Get full text

Application of Stem Cell Therapy for ACL Graft Regeneration by Canlong Wang, Yejun Hu, Shichen Zhang, Dengfeng Ruan, Zizhan Huang, Peiwen He, Honglu Cai, Boon Chin Heng, Xiao Chen, Weiliang Shen

“…In the clinic, 4 relevant completed trials have been reported, but only one trial with BMSCs showed improved outcomes, while 5 relevant trials are still in progress. …”
Get full text

The Potential of Night Jasmine (Nyctanthes arbor-tristis) Flower Extract as a Functional Ingredient in Yogurt Production: The Effects on Fermentation, Rheology, Sensory, and Antiox... by Pal Anil Kumar, Agarwal Aparna, Tripathi Abhishek Dutt, Khosravi-Darani Kianoush, Nandan Alisha, Tripathi Arunima, Hooda Ankita

“…The NJF-fortified yogurt was evaluated for sensory, textural, and physicochemical analyses, along with an ESI-MS assessment of bioactive components. Results showed that properties varied with NJF extract percentage, with trial T18 (3.68% NJF extract, 1.5 ml inoculum size, and 41°C temperature) achieving the highest sensory score and acceptability, as well as superior textural and antioxidant properties compared to control yogurt. …”
Get full text

Knowledge, practice, and information sources regarding infectious diseases among Chinese children and adolescents: a National-Level cross-sectional study by Yuan Zeng, Feifei Li, Wei Liang, Yinyue Liu, Zhiyong Zou, Julien S. Baker, Yanhui Dong, Jun Ma, Jie Hu, Yide Yang, Bin Dong

“…Methods This study used data collected from the baseline survey of a China national multi-centered cluster-randomized controlled trial in 2013. A total of 30,287 children completed a questionnaire package that included measures for knowledge, preventive practice and information sources related to infectious diseases. …”
Get full text

Home-based transcranial direct current stimulation paired with cognitive training to reduce fatigue in multiple sclerosis by Leigh Charvet, Judith D. Goldberg, Xiaochun Li, Pamela Best, Matthew Lustberg, Michael Shaw, Lana Zhovtis, Josef Gutman, Abhishek Datta, Marom Bikson, Giuseppina Pilloni, Lauren Krupp

“…A total of 117 participants were randomized, with 92% completing all treatment sessions. Both groups showed significant reductions in fatigue, with no significant difference between them. …”
Get full text