Activated Protein C Does Not Alleviate the Course of Systemic Inflammation in the APCAP Trial by Lea Kyhälä, Panu Mentula, Leena Kylänpää, Eeva Moilanen, Pauli Puolakkainen, Ville Pettilä, Heikki Repo

“…Our finding is in accordance with the clinical findings in the APCAP trial indicating that the intervention did not affect evolution of multiple organ dysfunctions.…”
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ENDOSCOPIC SURGERY FOR TREATING SPINAL STENOSIS: AN INTEGRATIVE REVIEW OF RANDOMIZED CLINICAL TRIALS by Rafael Augusto da Silva Aparício, Rodrigo Freitas Maringoni de Oliveira, Felipe de Almeida Pinto, Carlos Gorios, Lorran Azevedo Zanon, Alessandra Masi

“…Only randomized clinical trials published in the last 10 years were included in the sample. …”
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A network meta-analysis of therapies for hyperphosphatemia in CKD based on randomized trials by Congyang Zheng, Jia Liu, Tao Wang, Haiyang Hu, Yuanyuan Chen

“…All randomized controlled trials on hyperphosphatemia published from January 2013 to November 2023 were searched from CNKI, VIP database, Wanfang database, PubMed, Scopus, and Cochrane databases. …”
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Use of the consort-ai protocol in reporting artificial intelligence applications in clinical trials by Mustafa Agah Tekindal, Melike Tekindal, Mert Demirsöz, Zeynep Özel

“…<p> <b>Results: </b>The obtained findings showed that the agreement between raters was statistically significant. …”
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The Effects of Vestibular Rehabilitation on Poststroke Fatigue: A Randomized Controlled Trial Study by Amin Ghaffari, Bahador Asadi, Armin Zareian, Malahat Akbarfahimi, Gholam Reza Raissi, Fahimeh Fathali Lavasani

“…Patients with a history of stroke took part voluntarily in a single-blind clinical trial. The participants were allocated to control and experimental groups randomly. …”
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Advancements in Managing Anthracycline-Induced Cardiotoxicity: Insights from Interventional Clinical Trials by Zhao M, Zhang X, Zhou D, Song J

“…This study aimed to evaluate interventional clinical trials targeting AIC and identify effective strategies.Methods: We reviewed clinical trials on AIC from International Clinical Trial Registration Platform (ICTRP), focusing on intervention strategies. …”
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Effect of floral therapy in mothers of premature newborns: A randomized controlled trial by Tatiana Carneiro de Resende, Karla Oliveira Marcacine, Erika de Sá Vieira Abuchaim, Marcia Barbieri, Maria Cristina Gabrielloni, Ana Cristina Freitas de Vilhena Abrão

“…Methods: The randomized, triple-blind, placebo-controlled clinical trial was conducted with 117 postpartum women. They were divided into intervention (with five-flower) and control groups. …”
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Preferences and Attitudes Towards Digital Communication and Symptom Reporting Methods in Clinical Trials by McDowell B, Dumais KM, Gary ST, de Gooijer I, Ward T

“…Respondents preferred to communicate with friends/family via text messages (80.4%) over other methods. In clinical trial settings, participants are willing to use messaging methods to communicate with their physician. …”
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Hydrophobic and Hydrophilic IOLs in Patients with Uveitis &ndash; A Randomised Clinical Trial by Pålsson S, Schuborg C, Sterner B, Andersson Grönlund M, Zetterberg M

“…This randomised controlled trial compares inflammation, improvement in vision, and possible complications in patients that received two differing types of intraocular lenses. …”
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Deciphering the effect of exercise timing on glucose metabolism: a randomised controlled trial by Fabienne Bruggisser, Denis Infanger, Henner Hanssen, Raphael Knaier

“…Pairwise comparisons of the exercise groups showed varying magnitudes of differences in AUC, likewise accompanied by considerable uncertainty. …”
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Efficacy and Safety of Risankizumab in Patients with Psoriasis Showing Suboptimal Response to Secukinumab or Ixekizumab: Results from a Phase 3b, Open-Label, Single-Arm (aIMM) Stud... by Richard B. Warren, Lev Pavlovsky, Antonio Costanzo, Michael Bukhalo, Neil J. Korman, Yu-Huei Huang, Georgios Kokolakis, Andreas Pinter, Nadia Ibrahim, Yanbing Zheng, Leonidas Drogaris, Vassilis Stakias, Ahmed M. Soliman, Simone Rubant, Diamant Thaçi

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Beneficial and harmful effects of duloxetine versus placebo, ‘active placebo’ or no intervention for adults with major depressive disorder: a systematic review with meta-analysis a... by Christian Gluud, Marija Barbateskovic, Joanna Moncrieff, Faiza Siddiqui, Janus C Jakobsen, Mathias Maagaard, Sophie Juul, Johanne Juul Petersen, Caroline Barkholt Kamp, Mark Abie Horowitz, Kiran Kumar Katakam

“…Trial sequential analysis showed that we did not have enough information to assess the effects of duloxetine on serious adverse events (SAEs) (OR 0.67, 95% CI 0.44 to 1.02; I2=0.0%; 19 trials) or suicide or suicide attempts (OR 1.08, 95% CI 0.37 to 3.16; six trials). …”
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Weight loss for overweight and obese patients with prostate cancer: a study protocol of a randomised trial comparing clinic-based versus Telehealth delivered EXercise and nutrition... by Robert U Newton, Daniel A Galvão, Dennis R Taaffe, Suzanne K Chambers, David Joseph, Amanda Devine, Colin I Tang, Nigel Spry, Emily Jeffery, Dickon Hayne, Pedro Lopez, P Lyons-Wall, Christine Kudiarasu

“…Outcomes from the study will be published in academic journals and presented in scientific and consumer meetings.Trial registration number ACTRN12621001312831.…”
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Efficacy and safety of Jianpi Qinghua granules for non-erosive reflux disease with spleen deficiency and damp-heat syndrome: a multicenter, randomized, double-blind, placebo-contro... by Tai Zhang, Tai Zhang, Tai Zhang, Tai Zhang, Guang Bai, Wei Wang, Lin Liu, Zhenghua Zhou, Haijie Ji, Beihua Zhang, Beihua Zhang, Beihua Zhang, Xudong Tang, Xudong Tang

“…Current treatments like proton pump inhibitors show limited efficacy for many NERD patients, necessitating alternative approaches. …”
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Short-term effects of 448 kilohertz radiofrequency stimulation on plantar fascia measured by quantitative ultrasound elastography and thermography on active healthy subjects: an op... by Daniel Aguilar-Nuñez, Pablo Cervera-Garvi, Ana Gonzalez-Muñoz, Santiago Navarro-Ledesma

“…Objective: This study is an open clinical trial. The aim of this study was to show the changes that occur in the viscoelastic properties of the plantar fascia (twenty healthy volunteers) measured by SEL and the changes in the plantar fascia temperature measured by thermography after the application of a 448 kHz capacitive resistive monopolar radiofrequency (CRMR) in active healthy subjects immediately after treatment and at the 1-week follow-up.Methods: Furthermore, to analyze if an intervention with 448 kHz CRMR in the plantar fascia of the dominant lower limb produces a thermal response in the plantar fascia of the non-dominant lower limb. …”
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Blind adaptive matching pursuit algorithm for signal reconstruction based on sparsity trial and error by Wen-biao TIAN, Zheng FU, Guo-sheng RUI

“…Compressed sensing is a novel signal processing theory that it introduces a novel way of acquiring compressible signals,the test times of existing sparsity trial and error algorithms were always large.The novel algorithm,blind sparsity adaptive matching pursuit (BSAMP) was proposed,could recover the original signal fast in the case of unknown sparsity.Firstly,the range of sparsity was determined,and each time half of values in current range were eliminated by trial and error test.Secondly,the number of atoms was twice the sparsity,which was united with the set of signal approximation support (got by last iteration) and then reconstructed the signal by solving least-squares problems.Last but not least,the least-squares approximation was pruned by weakly matching for next iteration.The results of simulation show that the novel algorithm can reconstruct signal faster and get larger recovery probability than other similar algorithms in the same conditions.…”
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Protocol for visual-acoustic intervention with service delivery in-person and via telepractice (VISIT) non-inferiority trial for residual speech sound disorder by Tara McAllister, Jonathan L. Preston, Elaine R. Hitchcock, Nina R. Benway, Jennifer Hill

“…Discussion By comparing outcomes in children randomized to receive a standard course of biofeedback treatment either via telepractice or in-person, this study will provide evidence-based guidance for clinicians seeking flexible service delivery options for a challenging and prevalent condition. Trial registration ClinicalTrials.gov identifier NCT06517225, 07/23/2024. …”
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Helicobacter pylori Eradication in Idiopathic Thrombocytopenic Purpura: A Meta-Analysis of Randomized Trials by Bum Jun Kim, Hyeong Su Kim, Hyun Joo Jang, Jung Han Kim

“…We performed the first meta-analysis of randomized trials to gain a better insight into the effect of H. pylori eradication in ITP patients. …”
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Use of amantadine in traumatic brain injury: an updated meta-analysis of randomized controlled trials by João Félix, Luísa Araújo, Antônio Henriques, Ana Pereira, Saul Carneiro

“…However, the efficacy of this drug in TBI patients remains poorly defined.MethodsWe performed a systematic review and meta-analysis of randomized trials (RCTs) evaluating the effects of amantadine in TBI patients. …”
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Where authority, speech acts and modality meet: A pragmatic analysis of the trial record of King Charles I by Minako Nakayasu, Michi Shiina

“…On the other hand, the authority of the Court, which is manifested in the Lord President’s speech, stays the same throughout the course of the trial. To summarise, this research shows how the judge and the defendant interacted with each other in a fluctuating power relationship in the courtroom, at the interfaces between authority, speech acts and modality, where their viewpoints and attitudes are reflected. …”
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