Effect of Vaginal Cream with the Combination of Honey, Olive, and Propolis on the Symptoms of Uterine Cervicitis Symptoms in Women: A Double-Blind Randomized Controlled Clinical Tr... by Hamideh Parsapour, Arezoo Shayan, Mehrnoosh Hosseinpoor, Seyedeh Zahra Masoumi, Farideh Kazemi, Shirin Moradkhani, Seyed Mohammad Hossein Oliaei, Zeinab Assareh, Mohammad Kazem Rashidi

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Effect of Millets Once a Day on Glycaemic Control among Women with Gestational Diabetes Mellitus in a Tertiary Care Setting – A Randomized Controlled Trial by Mahadevan Duraiswamy, Venkatachalam Jayaseelan, Jayalakshmy Ramakrishnan, Sasirekha Rengaraj, Yuvaraj Krishnamoorthy, Mohammed Kais, Murali Subbaiah

“…Adherence to the protocol was high. Trial Registration: CTRI Registry CTRI/2022/04/042013.…”
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Role of adductor canal block and genicular nerve block on postoperative pain and enhanced recovery in patients undergoing total knee arthroplasty: A randomized clinical trial by Bassel Mohammed Elfokery, Mustafa Seet, Tareef Ashour, Hatem Alharbi, Mujeeb Ashraf, Hatim Alshareef, Mohammad Nyaz, Rayan Bakhreba, Atif Sait

“…Patients and Methods: This randomized trial was conducted on 50 subjects aged 40–75 years who underwent TKA under spinal anesthesia. …”
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Impact of ELKa, the Electronic Device for Prandial Insulin Dose Calculation, on Metabolic Control in Children and Adolescents with Type 1 Diabetes Mellitus: A Randomized Controlled... by Agnieszka Kowalska, Katarzyna Piechowiak, Anna Ramotowska, Agnieszka Szypowska

“…The ELKa system improves metabolic control in children with T1DM under regular usage. The trial is registered at ClinicalTrials.gov, number NCT02194517.…”
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Clinical Comparison between HD-tDCS and tDCS for Improving Upper Limb Motor Function: A Randomized, Double-Blinded, Sham-Controlled Trial by Yaqin Zeng, Ruidong Cheng, Li Zhang, Shan Fang, Shaomin Zhang, Minmin Wang, Qian Lv, Yunlan Dai, Xinyi Gong, Feng Liang

“…This randomized, sham-controlled clinical trial included 69 patients with subcortical stroke. …”
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Cardiopulmonary fitness in children/adolescents with chronic kidney disease and the impact of exercise training: a systematic review and meta-analysis of observational study and ra... by Fan Zhang, Yan Bai, Liuyan Huang, Yifei Zhong

“…The results of a meta-analysis based on a pre-post single-arm trial showed that compared to baseline, exercise training improved the 6MWD by approximately 58.17 m (95% CI 16.27–100.06), with very low evidence.Conclusions This systematic review and meta-analysis of observational studies and clinical trials that included children/adolescents with CKD found that cardiorespiratory fitness is severely reduced in this population and that exercise training may be an effective strategy for improvement. …”
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Effect of Oral Vasopressors Used for Liberation from Intravenous Vasopressors in Intensive Care Unit Patients Recovering from Spinal Shock: A Randomized Controlled Trial by Ahmed Talaat Ahmed Ali, Mervat Anwar Abd EL-Aziz, Ahmed Mohamed Abdelhafez, Amr Mohamed Ahmed Thabet

“…A randomized controlled trial was conducted in the trauma ICU at the Assiut University Hospital in Egypt in patients with spinal shock who required intravenous vasopressor for ≥24 h. …”
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Does a multimedia education program work as a remedy for stress and burden in family caregivers of elderly heart attack patients? A clinical trial study by Maliheh Abbasi, Nadia Kolbadinezhad, Somayeh Rostami, Mahya Ahmadi

“…Accordingly, we designed a randomized controlled clinical trial to assess the effect of an educational program on perceived stress and care burden among family caregivers of elderly heart attack patients. …”
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Evaluation of Pain Intensity Caused by Nickel-Titanium Archwires of Different Sizes in the First Stage of Fixed Orthodontic Treatment: A Double-Blind Randomized Clinical Trial by Aydin Sohrabi, Shabnam Tahamtan, Sana Seyed Shariatdoust, Ali Rafighi

“…The aim of the present study was to comparatively assess pain induced by different-sized nickel-titanium archwires during the first stage of fixed orthodontic therapy.Methods and Materials: This double-blind randomized clinical trial included a total of 81 patients who received fixed orthodontic therapy. …”
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Achillea millefolium capsule improved liver enzymes and lipid profile compared to placebo in patients with type 2 diabetes: a double-blind randomized clinical trial by Shole Daneshvar-Ghahfarokhi, Hassan Ahmadinia, Tabandeh Sadeghi, Elham Basirat, Vahid Mohammadi-Shahrokhi

“…Trial registration Iranian Registry of Clinical Trials IRCT20230612058459N1 Registered on 2023–06–24.…”
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Secukinumab in the treatment of psoriatic arthritis: efficacy and safety results through 3 years from the year 1 extension of the randomised phase III FUTURE 1 trial by Philip J Mease, Arthur Kavanaugh, Andreas Reimold, Hasan Tahir, Jürgen Rech, Stephen Hall, Piet Geusens, Pascale Pellet, Evie Maria Delicha, Shephard Mpofu, Luminita Pricop

“…Objective To assess the long-term (3 year) efficacy and safety of secukinumab in patients with active psoriatic arthritis (PsA) in the extension phase of the FUTURE 1 study (NCT01892436).Methods Following the 2-year core trial, eligible patients receiving subcutaneous secukinumab 150 or 75 mg entered a 3-year extension phase. …”
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Comparative efficacy of lumbar and pelvic support on pain, disability, and motor control in women with postpartum pelvic girdle pain: a three-armed randomized controlled trial by Fahimeh-Sadat Jafarian, Mahmonir Jafari-Harandi, Gillian Yeowell, Ebrahim Sadeghi-Demneh

“…Clinical trial registration Iranian Registry of Clinical Trials IRCT20150210021034N11. …”
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Effectiveness of potent topical corticosteroids versus mild ones in primary care for children with moderate flare-ups of atopic dermatitis; results of a randomised controlled trial by Patrick J E Bindels, Arthur M Bohnen, Gijs Elshout, Suzanne G M A Pasmans, Karlijn F van Halewijn

“…Improvement in the QoL was significant at 4 weeks (1.0 vs 4.5, p=0.014) and 24 weeks (0.0 vs 2.0, p=<0.000).Conclusion Despite the small sample size, the data suggests a clinical benefit from starting with a potent TCS rather than a mild TCS when a flare-up of AD is moderate.Trial registration The Netherlands National Trial Register: NTR6679.…”
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A prospective randomized controlled trial comparing biphasic cartilage repair implant with microfracture in small chondral lesions of knee: findings at five-year-follow-up by Yao-Yi Kuo, Si-Qi Chiu, Wen-Pei Chang, Chih-Yu Chen, Chih-Hwa Chen, Chen-Kun Liaw, Cheng-Aun Tan, Pei-Wei Weng

“…Methods This randomized controlled clinical trial enrolled patients with symptomatic knee chondral lesions smaller than 3 cm2. …”
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Smartphone-Based Intervention Targeting Norms and Risk Perception Among University Students with Unhealthy Alcohol Use: Secondary Mediation Analysis of a Randomized Controlled Tria... by Joseph Studer, John A Cunningham, Elodie Schmutz, Jacques Gaume, Angéline Adam, Jean-Bernard Daeppen, Nicolas Bertholet

“…This study is a follow-up mediation analysis of the primary and secondary outcomes of a randomized controlled trial testing the effect of a smartphone-based intervention to reduce alcohol use. …”
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Evaluating the Impact of Pharmacotherapy in Augmenting Quit Rates Among Hispanic Adults in an App-Delivered Smoking Cessation Intervention: Secondary Analysis of a Randomized Contr... by Margarita Santiago-Torres, Kristin E Mull, Brianna M Sullivan, Ana Paula Cupertino, Ramzi G Salloum, Matthew Triplette, Michael J Zvolensky, Jonathan B Bricker

“…However, this combined approach was not effective with the US clinical guideline–based app (QuitGuide). Trial RegistrationClinicalTrials.gov NCT02724462; https://clinicaltrials.gov/study/NCT02724462 International Registered Report Identifier (IRRID)RR2-10.1001/jamainternmed.2020.4055…”
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Application of K-means algorithm based on A-D model in calling abnormal customer mining by Jian ZHOU, Yongge SHI, Meibin HE

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Advantages and challenges of using arterial spin labelling MRI to monitor cerebral blood flow in multi-centre clinical trials of neurodegenerative disease: Experience from the RADA... by Lina Jarutyte, Jan Petr, Nicholas Turner, Patrick G. Kehoe, Henk-Jan Mutsaerts, David L. Thomas

“…ASL was used in the Reducing Pathology in Alzheimer's Disease through Angiotensin TaRgeting (RADAR) multi-centre trial to pilot the assessment of the effects of the anti-hypertension drug losartan on cerebral blood flow (CBF). …”
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Comparative Evaluation of the Safety and Efficacy of Long-Term Use of Imidafenacin and Solifenacin in Patients with Overactive Bladder: A Prospective, Open, Randomized, Parallel-Gr... by Masayoshi Zaitsu, Koji Mikami, Noriko Ishida, Takumi Takeuchi

“…This study is the first long-term trial to show differences in the properties of anticholinergics that were not detected in short-term studies. …”
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Evaluating Meaningful Changes in Patient‐Reported Outcome Measurement Information System–Fatigue Scores from Three Phase 3 Clinical Trials of Sarilumab for Patients With Rheumatoid... by Clifton O. Bingham, Emily Molina, Amy Praestgaard, Stefano Fiore, David Cella

“…Methods Data from three phase 3 randomized controlled trials of patients with RA who received sarilumab—MOBILITY, TARGET, and MONARCH—were evaluated. …”
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