Issues of Recruitment and Rationale for Conducting Clinical Trials on Mutans Streptococci Suppression in Mothers by Walter A. Bretz, Odila P. S. Rosa, Salete M. B. Silva, Patricia Corby, Lisa Weissfeld, Walter J. Loesche

“…Recent studies in industrialized countries showed a negative coefficient for linear tests indicating significant decline overtime in the levels of MS in mothers. …”
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Normative examination of the considerations of pre-trial judge on distortion of the value of the instruments of evidence by Fadlan Fadlan, Apridony Apridony

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Activated Protein C Does Not Alleviate the Course of Systemic Inflammation in the APCAP Trial by Lea Kyhälä, Panu Mentula, Leena Kylänpää, Eeva Moilanen, Pauli Puolakkainen, Ville Pettilä, Heikki Repo

“…Our finding is in accordance with the clinical findings in the APCAP trial indicating that the intervention did not affect evolution of multiple organ dysfunctions.…”
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ENDOSCOPIC SURGERY FOR TREATING SPINAL STENOSIS: AN INTEGRATIVE REVIEW OF RANDOMIZED CLINICAL TRIALS by Rafael Augusto da Silva Aparício, Rodrigo Freitas Maringoni de Oliveira, Felipe de Almeida Pinto, Carlos Gorios, Lorran Azevedo Zanon, Alessandra Masi

“…Only randomized clinical trials published in the last 10 years were included in the sample. …”
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A network meta-analysis of therapies for hyperphosphatemia in CKD based on randomized trials by Congyang Zheng, Jia Liu, Tao Wang, Haiyang Hu, Yuanyuan Chen

“…All randomized controlled trials on hyperphosphatemia published from January 2013 to November 2023 were searched from CNKI, VIP database, Wanfang database, PubMed, Scopus, and Cochrane databases. …”
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The Effects of Vestibular Rehabilitation on Poststroke Fatigue: A Randomized Controlled Trial Study by Amin Ghaffari, Bahador Asadi, Armin Zareian, Malahat Akbarfahimi, Gholam Reza Raissi, Fahimeh Fathali Lavasani

“…Patients with a history of stroke took part voluntarily in a single-blind clinical trial. The participants were allocated to control and experimental groups randomly. …”
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Advancements in Managing Anthracycline-Induced Cardiotoxicity: Insights from Interventional Clinical Trials by Zhao M, Zhang X, Zhou D, Song J

“…This study aimed to evaluate interventional clinical trials targeting AIC and identify effective strategies.Methods: We reviewed clinical trials on AIC from International Clinical Trial Registration Platform (ICTRP), focusing on intervention strategies. …”
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Preferences and Attitudes Towards Digital Communication and Symptom Reporting Methods in Clinical Trials by McDowell B, Dumais KM, Gary ST, de Gooijer I, Ward T

“…Respondents preferred to communicate with friends/family via text messages (80.4%) over other methods. In clinical trial settings, participants are willing to use messaging methods to communicate with their physician. …”
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Hydrophobic and Hydrophilic IOLs in Patients with Uveitis – A Randomised Clinical Trial by Pålsson S, Schuborg C, Sterner B, Andersson Grönlund M, Zetterberg M

“…This randomised controlled trial compares inflammation, improvement in vision, and possible complications in patients that received two differing types of intraocular lenses. …”
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Deciphering the effect of exercise timing on glucose metabolism: a randomised controlled trial by Fabienne Bruggisser, Denis Infanger, Henner Hanssen, Raphael Knaier

“…Pairwise comparisons of the exercise groups showed varying magnitudes of differences in AUC, likewise accompanied by considerable uncertainty. …”
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Beneficial and harmful effects of duloxetine versus placebo, ‘active placebo’ or no intervention for adults with major depressive disorder: a systematic review with meta-analysis a... by Christian Gluud, Marija Barbateskovic, Joanna Moncrieff, Faiza Siddiqui, Janus C Jakobsen, Mathias Maagaard, Sophie Juul, Johanne Juul Petersen, Caroline Barkholt Kamp, Mark Abie Horowitz, Kiran Kumar Katakam

“…Trial sequential analysis showed that we did not have enough information to assess the effects of duloxetine on serious adverse events (SAEs) (OR 0.67, 95% CI 0.44 to 1.02; I2=0.0%; 19 trials) or suicide or suicide attempts (OR 1.08, 95% CI 0.37 to 3.16; six trials). …”
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Protocol for visual-acoustic intervention with service delivery in-person and via telepractice (VISIT) non-inferiority trial for residual speech sound disorder by Tara McAllister, Jonathan L. Preston, Elaine R. Hitchcock, Nina R. Benway, Jennifer Hill

“…Discussion By comparing outcomes in children randomized to receive a standard course of biofeedback treatment either via telepractice or in-person, this study will provide evidence-based guidance for clinicians seeking flexible service delivery options for a challenging and prevalent condition. Trial registration ClinicalTrials.gov identifier NCT06517225, 07/23/2024. …”
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Overview of Novel Antipsychotic Drugs: State of the Art, New Mechanisms, and Clinical Aspects of Promising Compounds by Letizia Biso, Marco Carli, Marco Scarselli, Biancamaria Longoni

“…Moreover, in the past few decades, discoveries in the pathophysiology of psychotic disorders have opened the way for experimenting with novel compounds that have alternative mechanisms of action, with some of them showing promising results in early trials. The scope of this review was to summarize the novel antipsychotics developed, their current experimental status, and their mechanisms of action. …”
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Efficacy and Safety of Risankizumab in Patients with Psoriasis Showing Suboptimal Response to Secukinumab or Ixekizumab: Results from a Phase 3b, Open-Label, Single-Arm (aIMM) Stud... by Richard B. Warren, Lev Pavlovsky, Antonio Costanzo, Michael Bukhalo, Neil J. Korman, Yu-Huei Huang, Georgios Kokolakis, Andreas Pinter, Nadia Ibrahim, Yanbing Zheng, Leonidas Drogaris, Vassilis Stakias, Ahmed M. Soliman, Simone Rubant, Diamant Thaçi

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Where authority, speech acts and modality meet: A pragmatic analysis of the trial record of King Charles I by Minako Nakayasu, Michi Shiina

“…On the other hand, the authority of the Court, which is manifested in the Lord President’s speech, stays the same throughout the course of the trial. To summarise, this research shows how the judge and the defendant interacted with each other in a fluctuating power relationship in the courtroom, at the interfaces between authority, speech acts and modality, where their viewpoints and attitudes are reflected. …”
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A randomized controlled trial on the effect of smartphone-based mental health application among outpatients with depressive and anxiety symptoms: A pilot study in Malaysia by Sharon Tan, Mohammad Ayob Bin Ismail, Tuti Iryani Mohd Daud, Rozita Hod, Norfazilah Ahmad

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Effects of Manual Acupuncture Versus Sham Acupuncture in patients with Post-Stroke Depression: A Randomized Clinical Trial by Conghui Wei, Jinling Chen, Qu Yang, Jingjing Xu, Qingsong Li, Fulin Li, Yu Liu, Jun Luo

“…Methods From October 28, 2022 to May 16, 2023, this single-center, single-blind, randomized clinical trial was conducted at the Second Affiliated Hospital of Nanchang University. …”
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An empowerment programme to improve diet quality during pregnancy – the Power 4 a Healthy Pregnancy cluster randomised controlled trial by Renske M. van Lonkhuijzen, Jeanne H. M. de Vries, Elske Brouwer-Brolsma, Susanne Cremers, Janine P. M. Faessen, Edith J. M. Feskens, Annemarie Wagemakers

“…This study lays the foundation for future empowerment-based interventions in maternal health contexts. Trial registration International Clinical Trial Registry Platform NL-OMON23191, date of registration: 19/05/2021.…”
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Weight loss for overweight and obese patients with prostate cancer: a study protocol of a randomised trial comparing clinic-based versus Telehealth delivered EXercise and nutrition... by Robert U Newton, Daniel A Galvão, Dennis R Taaffe, Suzanne K Chambers, David Joseph, Amanda Devine, Colin I Tang, Nigel Spry, Emily Jeffery, Dickon Hayne, Pedro Lopez, P Lyons-Wall, Christine Kudiarasu

“…Outcomes from the study will be published in academic journals and presented in scientific and consumer meetings.Trial registration number ACTRN12621001312831.…”
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Helicobacter pylori Eradication in Idiopathic Thrombocytopenic Purpura: A Meta-Analysis of Randomized Trials by Bum Jun Kim, Hyeong Su Kim, Hyun Joo Jang, Jung Han Kim

“…We performed the first meta-analysis of randomized trials to gain a better insight into the effect of H. pylori eradication in ITP patients. …”
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