Prothrombin complex concentrate for reversal of oral anticoagulants in patients with oral anticoagulation-related critical bleeding: a systematic review of randomised clinical tria... by Christian Ovesen, Jan Purrucker, Josefine Grundtvig, Theis Bech Mikkelsen, Christian Gluud, Janus Christian Jakobsen, Hanne Christensen, Thorsten Steiner

“…Results Three trials, randomising a total of 291 participants, evaluated PCC against two different active comparators in participants with VKA-related critical bleeding, and two trials, randomising a total of 534 participants, evaluated PCC against two different active comparators in participants with factor Xa-related critical bleeding. …”
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Delta large-channel endoscopy versus unilateral biportal endoscopy decompressive laminectomy for lumbar spinal stenosis: a prospective randomized controlled trial by Rushuo Wei, Weiqiang Liu, Mingdong Yu, Yushan Zhu, Ruzhan Yao, Bingwu Wang, Jesse Li-Ling

“…This randomized controlled trial aims to compare their perioperative outcomes, focusing on postoperative recovery and complications over time. …”
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Effect of motivational interviewing to promote advance care planning among palliative care patients in ambulatory care setting: a randomized controlled trial by Helen Yue-Lai Chan, Doris Yin-Ping Leung, Po-Tin Lam, Polly Po-Shan Ko, Raymond Wai-Man Lam, Kin-Shan Chan

“…Methods A two-arm parallel randomized controlled trial was conducted between January 2018 and December 2019 in the palliative care clinics of two hospitals. …”
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Comparative Assessment of 0.5% Levobupivacaine and 0.5% Ropivacaine for Anaesthetic Potency in Mandibular Third Molar Extractions: A Randomised Controlled Trial by Prachi Surolia, Rajanikanth Kambala, Nitin Bhola, Anchal Agarwal

“…Both Levobupivacaine and Ropivacaine showed similar efficacy in achieving the depth of anaesthesia during surgery, with no statistically significant difference observed (p=1.00). …”
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Cocktail of Ropivacaine, Morphine, and Diprospan Reduces Pain and Prolongs Analgesic Effects after Total Knee Arthroplasty: A Prospective Randomized Controlled Trial by Zhenyu Luo, Weinan Zeng, Xi Chen, Qiang Xiao, Anjing Chen, Jiali Chen, Haoyang Wang, Zongke Zhou

“…Results. The two groups showed no differences in terms of characteristics (P > 0.05). …”
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The Effect of Postoperative Tranexamic Acid and Dexamethasone on Quality of Recovery After Arthroscopic Rotator Cuff Repair: a Double-Blinded, Randomized Controlled Trial by Jiang X, Xu C, Yuan C, Gao W, Liu W, Wang Y, Wang H, Yu W, He Y

“…VAS scores at 5– 8 (placebo vs TXA+DEX, p = 0.014; TXA vs TXA+DEX, p = 0.002), 9– 12 (placebo vs TXA+DEX, p = 0.008; TXA vs TXA+DEX, p < 0.001), and 13– 16 (placebo vs TXA+DEX, p = 0.035; TXA vs TXA+DEX, p = 0.013) hours postoperatively showed a significant decrease for the TXA+DEX group compared with the control or TXA group. …”
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Does coenzyme Q10 improve semen quality and circulating testosterone level? a systematic review and meta-analysis of randomized controlled trials by Tunmise M. Akhigbe, Tunmise M. Akhigbe, Fabrael B. Fidelis, Fabrael B. Fidelis, Adebayo O. Adekunle, Adebayo O. Adekunle, Victory J. Ashonibare, Victory J. Ashonibare, Bolaji A. Akorede, Bolaji A. Akorede, Mansur S. Shuaibu, Mansur S. Shuaibu, Suliat A. Hassan, Cecilia A. Adegbola, Cecilia A. Adegbola, Precious J. Ashonibare, Precious J. Ashonibare, Opeyemi M. Oladapo, Opeyemi M. Oladapo, Adetomiwa E. Adeogun, Adetomiwa E. Adeogun, Adetomiwa E. Adeogun, Seun G. Bamidele, Seun G. Bamidele, Precious A. Oyedokun, Precious A. Oyedokun, Mungala Mukolokota, Mungala Mukolokota, Omotolani S. Kukoyi, Omotolani S. Kukoyi, Ayoola A. Oladipo, Ayoola A. Oladipo, Olayinka E. Adelowo, Olayinka E. Adelowo, Marvelous D. Akangbe, Marvelous D. Akangbe, Jennifer R. Hughes, Albert M. Ricken, Martine Culty, Maria C. W. Avellar, Roland E. Akhigbe, Roland E. Akhigbe

“…However, CoQ10 supplementation had no significant effect on semen volume (SMD 0.12 [95% CI: −0.13, 0.37] P= 0.34) and sperm concentration (SMD -6.69 [95% CI: −16.28, 2.90] P= 0.17).ConclusionOur study shows that CoQ10 supplementation increases total sperm count, total and progressive sperm motility, and the proportion of normally formed sperm in association with higher serum testosterone and inhibin B levels. …”
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Long-Term Safety and Efficacy of Lenabasum, a Cannabinoid Receptor Type 2 Agonist, in Patients with Dermatomyositis with Refractory Skin Disease: Follow-Up Data from a 3-Year Open-... by Caroline J. Stone, Geeta Ahuja, Lais Lopes Almeida Gomes, Joy Poroye, Daniella Forman Faden, Lillian Xie, Rui Feng, Barbara White, Victoria P. Werth

“…Methods: The phase 2 lenabasum trial enrolled patients with treatment-resistant, skin-predominant DM. …”
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Effectiveness and tolerability of lactic acid vaginal gel compared to oral metronidazole in the treatment of acute symptomatic bacterial vaginosis: a multicenter, randomized-contro... by Fiona Tidbury, Grégory Brülhart, Gabriela Müller, Elena Pavicic, Susanna Weidlinger, Gerrit Eichner, Michael von Wolff, Petra Stute

“…Trial registration number NCT02042287 (22.01.2014).…”
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Quality of the systematic reviews in cochrane multiple sclerosis related articles by Masoud Zeynalzadeh, Nasim Mahdavi, Morteza Atayi, Hanieh Salehi-Pourmehr, Sakineh Hajebrahimi

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Safety and effects of anti-obesity medications on weight loss, cardiometabolic, and psychological outcomes in people living with overweight or obesity: a systematic review and meta... by Leiling Liu, Zhiqi Li, Wenrui Ye, Pu Peng, Yurong Wang, Luqing Wan, Jiangnan Li, Mei Zhang, Yihua Wang, Runqi Liu, Danyan Xu, Jingjing Zhang

“…Methods: This systematic review and meta-analysis included searches of Web of Science, PubMed, and Cochrane Central Register of Controlled Trials from inception to June 8, 2024. Randomised controlled trials evaluating weight-loss pharmacotherapies approved by the Food and Drug Administration (FDA) or European Medicines Agency (EMA) for treating overweight or obesity were included. …”
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Les accompagnateurs dans l’enseignement supérieur. Quel apprentissage suite aux affordances saisies dans un environnement multiculturel ? by Patricia Rached

“…They make use of 4 modes of learning : praxis, social interaction, trial and error, and self-documentation.…”
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Analysis of Tobacco Cessation Programs in Dental Settings by Niharika Benjamin, Varsha Choubey, Meenakshi Bhasin, Bedkekar Sushma, Anushree Choudhary, Pallavi Ammu Thomas

“…Results: At 6 months, the intervention group showed a significantly higher quit rate (45%) compared to the control group (20%) (P < 0.001). …”
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Multi-environmental traits selection and farmer's participatory assessment of mean performance and stability of orange-fleshed sweet potato genotypes in Benin by Idrissou Ahoudou, Nicodeme V. Fassinou Hotegni, Dêêdi E.O. Sogbohossou, Tania L.I. Akponikpè, Charlotte O.A. Adjé, Françoise Assogba Komlan, Ismail Moumouni-Moussa, Enoch G. Achigan-Dako

“…The across-environment likelihood ratio test (LRT) showed significant differences across environments, genotypes, and GEIs for all traits studied, except for the number of marketable roots (NMR). …”
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Feasibility and preliminary efficacy of a physical activity intervention in adults with lymphoma undergoing treatment by Juliana V. Costa, Alexander R. Lucas, Shannon L. Mihalko, Peter H. Brubaker, Alexandra Marshall, Brianna Leitzelar, Brianna R. Wolle, Samuel Norton, R. Lee Franco, Jeremy Via, Victor Yazbeck, Rakhee Vaidya, Mary Beth Seegars, Ralph D’Agostino, Lynne Wagner, W. Gregory Hundley

“…Potential Implications for Cancer Survivors: Physical activity may be beneficial for improving exercise capacity and health-related quality of life in patients undergoing chemotherapy. Trial registration #NCT01719562 ClinicalTrials.gov. …”
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Real-Time fMRI Neurofeedback Modulation of Dopaminergic Midbrain Activity in Young Adults With Elevated Internet Gaming Disorder Risk: Randomized Controlled Trial by Anqi Gu, Cheng Lam Chan, Xiaolei Xu, Joseph P Dexter, Benjamin Becker, Zhiying Zhao

“…We show that, after 2 sessions of neurofeedback training, participants successfully downregulated their brain responses to gaming cues, suggesting the therapeutic potential of rt-fMRI NF for IGD (Trial Registration: ClinicalTrials.gov NCT06063642; https://clinicaltrials.gov/study/NCT06063642).…”
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Effects of Meaningful Action Observation Therapy on Occupational Performance, Upper Limb Function, and Corticospinal Excitability Poststroke: A Double-Blind Randomized Control Tria... by Aryan Shamili, Afsoon Hassani Mehraban, Akram Azad, Gholam Reza Raissi, Mohsen Shati

“…Method. A randomized control trial was designed to compare between experimental (n=13) and control groups (n=14). …”
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The Effect of Zinc Supplementation on Glycemic, Weight, and Blood Pressure Control in Patients With Type 2 Diabetes Mellitus: A Double‐Blind Randomized Controlled Trial by Mehrab Sayadi, Sara Javadpour Nowbandegani, Fatemeh Balaghi Inalou, Bahman Nazemzadegan, Shirzad Javidi Alsaadi, Mohammadreza Eskandari, Matin Sepehrinia

“…Trial Registration This trial was registered on the Iranian Registry of Clinical Trials (IRCT) website with code number 29627 on September 18, 2018.…”
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An mHealth Intervention With Financial Incentives to Promote Smoking Cessation and Physical Activity Among Black Adults: Protocol for a Feasibility Randomized Controlled Trial by Adam Alexander, Michael Businelle, Marshall Cheney, Amy Cohn, Lorna McNeill, Kevin Short, Summer Frank-Pearce, David Bradley, Kimberly Estrada, Iván Flores, Jack Fronheiser, Darla Kendzor

“…Trial RegistrationClinicalTrials.gov NCT05188287; https://clinicaltrials.gov/ct2/show/NCT05188287 International Registered Report Identifier (IRRID)PRR1-10.2196/69771…”
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Effects of a social participation-focused virtual reality intervention for community-dwelling stroke survivors with physical disabilities: a randomised controlled trial protocol by Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Vivian Wing Yan Lee, Kai Chow Choi, Alexander Yuk Lun Lau, David R Thompson, Eddie Chi Fai Kwok

“…Introduction Studies show that stroke survivors encounter physical and psychological limitations that restrict their participation in social and community activities. …”
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