Low-Dose Ketamine Infusion for Perioperative Pain Management in Patients Undergoing Laparoscopic Gastric Bypass: A Prospective Randomized Controlled Trial by Mitchell T. Seman, Shawn H. Malan, Matthew R. Buras, Richard J. Butterfield, Kristi L. Harold, James A. Madura, David M. Rosenfeld, Andrew W. Gorlin

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Comparative efficacy and safety of GLP-1 receptor agonists for weight reduction: A model-based meta-analysis of placebo-controlled trials by Haoyang Guo, Juan Yang, Jihan Huang, Ling Xu, Yinghua Lv, Yexuan Wang, Jiyuan Ren, Yulin Feng, Qingshan Zheng, Lujin Li

“…The FDA has approved glucagon-like peptide-1 (GLP-1) receptor agonists such as Liraglutide, Semaglutide, and the GLP-1/gastric inhibitory polypeptide (GIP) dual agonist Tirzepatide for the treatment of obesity. Clinical trials of GLP-1/GIP/glucagon(GCG) triple agonists are ongoing. …”
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Spirituality-based palliative care education on quality of life, death anxiety, and resilience of heart failure patients: Randomized controlled clinical trial by Roghayeh Balaghi Inaloo, Mostafa Bijani, Leila Nikrouz, Azizallah Dehghan, Abdulhakim Alkamel, Ali Taghinezhad, Zahra Khiyali

“…The intervention group showed significant improvements in quality of life, death anxiety, and resilience scores both immediately after the intervention and at the three-month follow-up (p < 0.05). …”
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Remimazolam for the prevention of emergence agitation in adults following nasal surgery under general anesthesia: a prospective randomized clinical controlled trial by Yanfei Lu, Qiaomin Xu, Hong Dai, Jimin Wu, Mengting Ai, Haiyan Lan, Xiaoli Dong, Gongchen Duan

“…Trial registration The trial was registered, before patient enrollment, in the Chinese Clinical Trial Registry ( www.chictr.org.cn ) (clinical trial number: ChiCTR2300075300; Principal Investigator: Gongchen Duan; date of registration: 31 August 2023; https://www.chictr.org.cn/bin/project/edit?…”
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Safety and efficacy of CD33-targeted CAR-NK cell therapy for relapsed/refractory AML: preclinical evaluation and phase I trial by Ruihao Huang, Xiaoqi Wang, Hongju Yan, Xu Tan, Yingying Ma, Maihong Wang, Xiao Han, Jia Liu, Li Gao, Lei Gao, Guangjun Jing, Cheng Zhang, Qin Wen, Xi Zhang

“…CD33 CAR-NK cells demonstrated efficacy comparable to that of CD33 CAR-T cells but showed limited toxicity to hematopoietic stem cells (HSCs). …”
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Comparative analysis of integer factorization algorithms by G. Kimsanova, R. Ismailova, R. Sultanov

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Safety and efficacy of oral cancer vaccine B440 in patients with PD-1/PD-L1 inhibitor-resistant advanced urothelial cancer: a study protocol for a phase 1 multicenter, open-label,... by Junya Furukawa, Yasumasa Kakei, Sae Murakami, Hiroshi Kita, Hideto Ueki, Takuto Hara, Jun Teishima, Nobuyuki Hinata, Hideaki Miyake, Masato Fujisawa, Toshiro Shirakawa

“…Secondary outcomes are the presence or absence of a response, the best overall response and PFS. Discussion If this trial shows B440 to be safe and effective, it may lead to a late phase randomized controlled trial in advanced urothelial cancer. …”
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A park-based group mobility program for older adults with difficulty walking outdoors: a qualitative process evaluation of the Getting Older Adults Outdoors (GO-OUT) randomized con... by Kristina M. Kokorelias, Jacquie Ripat, Ruth Barclay, C. Allyson Jones, Nancy E. Mayo, Theresa Grant, Stephanie Scodras, Kyla Alsbury-Nealy, Charlotte Ryder-Burbidge, Nancy M. Salbach

“…Abstract Background The Getting Older Adults Outdoors (GO-OUT) randomized controlled trial showed that a workshop and 10-week park-based outdoor walk group (OWG) was superior to the workshop and 10 weekly reminders (WR) with increasing walking capacity, but not outdoor walking activity, health-promoting behavior, or successful aging, among older adults with difficulty walking outdoors. …”
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Levilactobacillus brevis CD2 as a multifaceted probiotic to preserve oral health: results of a double-blind, randomized, placebo-controlled trial in healthy adults by Serena Altamura, Francesca Lombardi, Francesca Rosaria Augello, Antonella Barone, Mario Giannoni, Benedetta Cinque, Davide Pietropaoli

“…Results After four weeks, the probiotic group showed significant improvements in BoP and PI compared to baseline and placebo. …”
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Feasibility of a pragmatic randomized adaptive clinical trial to evaluate a brief negotiational interview for harmful and hazardous alcohol use in Moshi, Tanzania. by Catherine A Staton, Kaitlyn Friedman, Ashley J Phillips, Mary Catherine Minnig, Francis M Sakita, Kennedy M Ngowi, Brian Suffoletto, Jon Mark Hirshon, Monica Swahn, Blandina T Mmbaga, Joao Ricardo Nickenig Vissoci

“…<h4>Trial registration</h4>Trial registration number NCT02828267. https://classic.clinicaltrials.gov/ct2/show/NCT02828267.…”
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Effectiveness of an mHealth Intervention With Short Text Messages to Promote Treatment Adherence Among HIV-Positive Mexican Adults: Randomized Controlled Trial by Luis Eduardo Del Moral Trinidad, Jaime Federico Andrade Villanueva, Pedro Martínez Ayala, Rodolfo Ismael Cabrera Silva, Melva Guadalupe Herrera Godina, Luz Alicia González-Hernández

“…MethodsA randomized controlled trial was performed at the Hospital Civil de Guadalajara – Fray Antonio Alcalde on HIV-positive adults who had initiated ART. …”
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Comparing the Efficacy of Triamcinolone Acetonide Iontophoresis versus Topical Calcipotriol/Betamethasone Dipropionate in Treating Nail Psoriasis: A Bilateral Controlled Clinical T... by Nasrin Saki, Shahla Hosseinpoor, Alireza Heiran, Ali Mohammadi, Mehdi Zeraatpishe

“…Results. The results did not show any difference between the therapeutic effects of TI and topical calcipotriol/betamethasone dipropionate regarding the nail bed score (P value =  .356), matrix score (P value =  .137), and total NAPSI (P-value =  .098). …”
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Clinical Trial Assessing the Efficacy of Gabapentin Plus B Complex (B1/B12) versus Pregabalin for Treating Painful Diabetic Neuropathy by Alberto Mimenza Alvarado, Sara Aguilar Navarro

“…This trial is registered with ClinicalTrials.gov NCT01364298.…”
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Psychological interventions for depression among informal caregivers of older adult populations: protocol of a systematic review and meta-analysis of randomised controlled trials by Danelle Pettman, Louise von Essen, Oscar Blomberg, Joanne Woodford, Erika Mårtensson, Renita Sörensdotter

“…This review aims to address this gap and will inform the development of a psychological intervention targeting depression among adult-child caregivers of older parents, given many studies show that among informal caregivers of older adults, adult children experience specific difficulties and needs for psychological support. …”
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The Effect of Autologous Dendritic Cell Immunotherapy on Kidney Function and Endothelial Dysfunction of Patients with Diabetic Kidney Disease (DKD): An Open Label Clinical Trial by Martina Lily Yana, Enda Cindylosa Sitepu, Jonny, Linda Chiuman, I Nyoman Ehrich Lister, Terawan Agus Putranto

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The regular effects of concurrent aerobic and resistance exercise on global cognition in healthy elderly populations: A systematic review with meta-analysis of randomized trials by Liang Ding, Lijie Lou, Mingyang Zhang, Xing Zhang

“…Randomized controlled trials involving healthy older adults aged ≥65 years that assessed the cognitive effects of concurrent exercise were included. …”
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Therapeutic effects of probiotics on symptoms of irritability/emotional lability associated with neurodevelopmental conditions: A systematic review and meta-analysis of placebo-con... by Ping-Wen Huang, Chen Chia-Min, Cheuk-Kwan Sun, Yu-Shian Cheng, Yen-Hsiang Tang, Cheng Liu, Kuo-Chuan Hung

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Augmenting neurocognitive remediation therapy to Preventive Cognitive Therapy for partially remitted depressed patients: protocol of a pragmatic multicentre randomised controlled t... by Huibert Burger, Claudi Bockting, Marlies Brouwer, Gert J Geurtsen, Amanda M Legemaat, Johanne G J van der Stappen, Maria Semkovska, Isidoor O Bergfeld, Nicoline Lous, Damiaan A J P Denys

“…Outcomes will be made publicly available.Trial registration number NL9582.…”
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Effectiveness of a Mobile Health Intervention (DOT Selfie) in Increasing Treatment Adherence Monitoring and Support for Patients With Tuberculosis in Uganda: Randomized Controlled... by Juliet Nabbuye Sekandi, Esther Buregyeya, Sarah Zalwango, Damalie Nakkonde, Patrick Kaggwa, Trang Ho Thu Quach, David Asiimwe, Lynn Atuyambe, Kevin Dobbin

“…This evidence highlights the potential of digital technologies to improve treatment adherence monitoring and support in high TB burden settings with limited human resources. Trial RegistrationClinicalTrials.gov NCT04134689; http://clinicaltrials.gov/ct2/show/NCT04134689…”
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The Combined Effect of Multisensory Stimulation and Therapist Support on Physical and Mental Health of Older Adults Living in Nursing Homes: Pilot Randomized Controlled Trial by Sewar Khatib, Yuval Palgi, Yoni K Ashar, Natalya Polyvyannaya, Pavel Goldstein

“…This brief intervention can be readily implemented to improve well-being and optimize therapeutic resources in nursing home settings. Trial RegistrationClinicalTrials.gov NCT05394389; https://clinicaltrials.gov/ct2/show/NCT05394389…”
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