Unloader brace or high tibial osteotomy in the treatment of the young patient with medial knee osteoarthritis: a randomized controlled trial by Mark Stam, Joost Verschueren, Mark V van Outeren, Reinoud W Brouwer, Robert D A Gaasbeek, Sorin G Blendea, Eline M van Es, Max Reijman, Sita M A Bierma-Zeinstra

“…Methods: We recruited patients from 9 Dutch hospitals between August 2014 and February 2019 for an open-labeled multi-center randomized controlled trial (Dutch Trial Register NL4200). Patients aged 18 to 65 years with symptomatic medial compartmental knee OA were randomized to either a valgus unloader brace or an HTO. …”
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The Efficacy of Functional and Traditional Exercise on the Body Composition and Determinants of Physical Fitness of Older Women: A Randomized Crossover Trial by Antônio Gomes de Resende-Neto, José Carlos Aragão-Santos, Bruna Caroline Oliveira-Andrade, Alan Bruno Silva Vasconcelos, Clodoaldo Antônio De Sá, Felipe José Aidar, Josimari Melo DeSantana, Eduardo Lusa Cadore, Marzo Edir Da Silva-Grigoletto

“…This is a randomized clinical trial in which participants performed two 12-week periods of different training methods, separated by eight weeks of washout. …”
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Investigating the effectiveness of ailurophobia treatment using virtual reality technique compared to metacognitive therapy: a randomized clinical trial by Alireza Ebrahimi, Farzad Akbarzadeh, Negar Asgharipour, Razie Salehabadi, Malihe Arjamandi

“…Registry Iranian Registry of Clinical Trials.…”
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Effect of Nebulized Morphine on Dyspnea of Mustard Gas-Exposed Patients: A Double-Blind Randomized Clinical Trial Study by Majid Shohrati, Mostafa Ghanei, Asghar Amini Harandi, Soniya Foroghi, Ali Amini Harandi

“…Conclusion. Our results showed the clinical benefit of nebulized morphine on respiratory complaints of patients due to exposure to SM without significant side effects.…”
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Cognitive Training and Transcranial Direct Current Stimulation for Mild Cognitive Impairment in Parkinson’s Disease: A Randomized Controlled Trial by Blake J. Lawrence, Natalie Gasson, Andrew R. Johnson, Leon Booth, Andrea M. Loftus

“…Interventions lasted 4 weeks, with cognitive and functional outcomes measured at baseline, post-intervention, and follow-up. The trial was registered with the Australian New Zealand Clinical Trials Registry (ANZCTR: 12614001039673). …”
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Procedure-Related Access Site Pain Multimodal Management following Percutaneous Cardiac Intervention: A Randomized Control Trial by Liuda Brogiene, Aiste Urbonaite, Giedre Baksyte, Andrius Macas

“…To address this, a randomized controlled trial was conducted in Hospital of Lithuanian University of Health Sciences Kauno klinikos in 2018. …”
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Electroacupuncture for mild-to-moderate dry eye: study protocol for a multicentre, randomised, single-blind, sham-controlled trial by Yue Zhao, Guang Yang, Yun-Qiong Lu, Mei-Yan Li, Jue Hong, Yan-Ting Yang, Xue-Jun Wang, Xie-He Kong, Zhao Ma, Xin-Yun Huang, Yue-Lan Zou, Xing-Tao Zhou, Xiao-Peng Ma

“…Currently, there is no recognised long-term, effective treatment to alleviate DE. Clinical evidence shows that electroacupuncture (EA) can improve DE symptoms, tear secretion and tear film stability, but it remains controversial whether it is just a placebo effect. …”
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The Effects of Confiding on Shift Work Nurses’ Emotion Regulation and Self-Perceived Well-Being: An Online Randomized Controlled Trial by Cui Lu, Yawen Sun, Chunyan Wang, Tianyong Chen, Yi Tang

“…Furthermore, self-rated general health and sleep quality showed significant improvement in the intervention group compared to pre-test levels, but no significant differences were observed between the experimental and control groups. …”
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The effect of telephone counseling with a positive psychology approach on quality-of-life in postmenopausal women: A randomized controlled trial by Shifteh Hashemzadeh, Traneh Emamgholi Khoshechin, Leila Rastegari, Saeedeh Zenoozian

“…Methods: This randomized controlled trial was conducted on 70 eligible postmenopausal women (each group=35). …”
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Clinical trials since 2020 of rapid anti-suicidal ideation effects of ketamine and its enantiomers: a systematic review by Sumra Sajid, J. John Mann, Michael F. Grunebaum

“…Methods We conducted a systematic review of clinical trials (CT) since 2020 of racemic ketamine or one of its enantiomers’ (R/S) potential to reduce suicidal ideation or behavior (SIB). …”
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Effects of prenatal exercise interventions on maternal body composition: A secondary analysis of the FitMum randomized controlled trial. by Caroline Borup Roland, Parisa Seyedhosseini, Signe de Place Knudsen, Anne Dsane Jessen, Ida Karoline Bach Jensen, Jane M Bendix, Gerrit van Hall, Stig Molsted, Saud Abdulaziz Alomairah, Ellen Løkkegaard, Bente Stallknecht, Tine D Clausen

“…This study presents secondary outcomes of the FitMum randomized controlled trial, which included healthy inactive pregnant women at gestational age ≤ 15+0 weeks. …”
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Comparison of Maylard and Cherney incisions' outcomes in hysterectomy surgery for benign indications: a double-blind randomized controlled trial by Maryam Vaezi, Roghayeh Zarei, Hosein Azizi

“…Materials and methods A randomized controlled trial was conducted in Al-Zahra Women’s Tertiary Referral University Hospital. …”
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Effects of exercise intensity on nutritional status, body composition, and energy balance in patients with COPD: a randomized controlled trial by Tomoyuki Ikeuchi, Kazuya Shingai, Katsuyuki Ichiki, Takeo Jimi, Tetsuya Kawano, Kaori Kato, Toru Tsuda

“…Results The analysis included 30 participants (AA, n = 15; AB, n = 15). The AA group showed significant increases in body composition, dietary intake, nutritional status, muscle strength, and exercise capacity at week 4 than at week 2, with no significant changes in the AB group. …”
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Comparing the effect of bananas and dates on the reactivity of the non-reactive fetus non-stress test: A randomized clinical trial by Sheida Shabanian, Shirin Moazen Dehkordi, Mahboubeh Taghipour, Afsaneh Malekpour

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Efficacy of Wii-Fit on Static and Dynamic Balance in Community Dwelling Older Veterans: A Randomized Controlled Pilot Trial by Kalpana P. Padala, Prasad R. Padala, Shelly Y. Lensing, Richard A. Dennis, Melinda M. Bopp, Christopher M. Parkes, Mark K. Garrison, Patricia M. Dubbert, Paula K. Roberson, Dennis H. Sullivan

“…A prospective randomized controlled parallel-group trial was conducted at Veterans Affairs Medical Center. …”
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Effects of Hook Maneuver on Oxygen Saturation Recovery After −40 m Apnea Dive—A Randomized Crossover Trial by Francisco DeAsís-Fernández, Álvaro Reina-Varona, Evangelos Papotsidakis, Juan Lafuente, José Fierro-Marrero

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Reduction of Hepatic Fat Content by Dulaglutide for the Treatment of Diabetes Mellitus: A Two‐Centre Open, Single‐Arm Trial by Chuanfeng Liu, Yu Xin, Yajing Huang, Lili Xu, Ruizhi Zhou, Yangang Wang, Wei Wang

“…However, the relationship between quantitative reduction in hepatic fat content and improvement of pancreatic islet function by GLP‐1RA is unclear. Methods This trial was a single‐arm open cohort study. A total of 38 patients with T2DM and NAFLD were enrolled in the GLP‐1RA treatment group. …”
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Comprehensive safety evaluation of isatuximab in multiple myeloma using disproportionality analysis of FAERS and meta-analysis of randomized controlled trials by Muhammed Favas Karimbanathottathil, Beema T Yoosuf, M Mamatha, Dipika Bansal

“…For the meta-analysis, safety outcomes of isatuximab in adult patients were reviewed from RCTs sourced from databases such as PubMed, EMBASE, and ClinicalTrials.gov, employing a random-effects meta-analysis to determine the risk ratio (RR) with 95% CI. …”
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Effects of home-based virtual reality upper extremity rehabilitation in persons with chronic stroke: a randomized controlled trial by Hiroyuki Ase, Kaoru Honaga, Mami Tani, Tomokazu Takakura, Futoshi Wada, Yuhei Murakami, Reina Isayama, Akira Tanuma, Toshiyuki Fujiwara

“…Methods This was a single-blind, randomized, controlled trial conducted at two centers. The subjects were 14 outpatients with chronic stroke more than 6 months after the onset of the stroke. …”
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Left ventromedial prefrontal cortex inhibitory rTMS as an anti-stress intervention in opioid use disorder: Trial design by Tabitha E. Moses, Danielle Lenz, Leslie H. Lundahl, Nicholas A. Mischel, Christine Rabinak, Mark K. Greenwald

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