A Randomized Placebo-Controlled Dose-Response Trial of Muvz™ for Knee and Low-Back Support in Physically Active Adults by Kalman D, Srivastava S, Desale A, Chatte Snr MD, Nalavade RJ, Shah Snr KM, Karvir S, Bhasale S

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Anaesthetic efficacy of intraligamentary injection compared to incisive nerve block using 3% mepivacaine hydrochloride: a randomized clinical trial by Suzan Salem, Islam Saad, Ramy Elmoazen, Ghada Amin Khalifa

“…The results suggest that ILI can be used as a sole anaesthetic technique during extraction of lower anterior and premolar teeth. Trial registration This trial was retrospectively registered on 27/01/2023 with the identifier ISRCTN83272316 in Isrctn.com.…”
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Efficacy and safety of Lutai Danshen Baishao granules for treating female melasma: A randomized, double-blind, placebo-controlled trial by Meiyu Lyu, Yi Yang, Jinlian Liu, Wenting Fei, Min Fu, Yunting Hong, Hongguo Rong, Chun Wang, Linyuan Wang, Jianjun Zhang

“…Methods: A randomized, double-blind, placebo-controlled trial was conducted at the Third Central Hospital of Tianjin, China from March to December 2023. …”
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Effect of conservative treatment on greater trochanteric pain syndrome: a systematic review and network meta-analysis of randomized controlled trials by Si-Qi Wang, Ning-Yi Guo, Wei Liu, Hong-jie Huang, Bing-bing Xu, Jian-quan Wang

“…Additionally, injection therapy showed significant advantages in improving functional outcomes measured by using the Harris Hip Scale. …”
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The Effectiveness and Safety of Mesenchymal Stem Cells in the Treatment of Osteoarthritis: A Systematic Review and Meta-analysis of 28 Randomized Controlled Trials by Zhiyong Long, Mingsheng Zhang, Tianqing Zhang, Liuting Zeng, Kailin Yang, Tiejun Yang, Ganpeng Yu, Jun Li, Yang Wu, Hua Chen

“…The primary outcomes showed that MSCs may reduce WOMAC pain and VAS at the 3rd-month follow-up [WOMAC pain: -3.81 (-6.95, -0.68), P=0.02. …”
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Validating a digital depression prevention program for adolescents in Jordan: cultural adaptation and user testing in a randomized controlled trial by Latefa Ali Dardas, Obada Al-leimon, Tracy Gladstone, Abd Arrahman Dabbas, Insaf Alammouri, Benjamin Van Voorhees

“…Future implementations should consider strategies to actively engage parents to foster a supportive environment that promotes the well-being of adolescents.Clinical trial registrationhttps://doi.org/10.1186/ISRCTN14751844, identifier ISRCTN14751844.…”
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Inspiratory muscle training facilitates liberation from mechanical ventilation in subacute critically ill patients—a randomized controlled trial by Shu-Jane Wang, Tien-Pei Fang, Tien-Pei Fang, Daniel D. Rowley, Nan-Wei Liu, Jui-O Chen, Jui-Fang Liu, Jui-Fang Liu, Hui-Ling Lin, Hui-Ling Lin, Hui-Ling Lin

“…A moderate correlation between increased creatinine levels and respiratory muscle strength was observed, suggesting that creatinine may be a potential biomarker for muscle recovery during IMT.Clinical trial registrationThis study was registered at ClinicalTrials.gov (NCT06611683).…”
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Differential effects of left DLPFC anodal and cathodal tDCS interventions on the brain in children with autism: A randomized controlled trial by Jiannan Kang, Juanmei Wu, Xinping Huang, Wenqin Mao, Xiaoli Li

“…Further correlation analysis revealed that in children who received anodal tDCS intervention, non-periodic exponent showed correlations with behaviors such as social communication. …”
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Impact of subgingival periodontal treatment on systemic markers of inflammation in patients with metabolic syndrome: a systematic review of randomized clinical trials by Marie Chavez, Asshly Ramirez, Akram Hernández-Vásquez, Daniel Comandé, Diego Azañedo

“…The other, with unclear risk of bias, showed no differences in CRP up to 12 months. Findings suggest that subgingival periodontal treatment with antibiotics reduces systemic inflammation for up to 6 months in patients with MS and PD. …”
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Yishenyangsui granule for degenerative cervical myelopathy: a randomized, double-blind, placebo-controlled trial with long-term follow-up by He Yin, Xin Chen, Zhiwei Liu, Zhiwei Liu, Bo Xu, Zhefeng Jin, Yan Liu, Baoyu Qi, Bin Tang, Ping Wang, Fanping Xu, Xu Wei, Jie Yu, Liguo Zhu, Liguo Zhu

“…Patient-reported outcomes including surgical treatment data, re-treatment data, and patient-reported condition were collected for long-term follow-up. This trial was approved by the ethics committee of WangJing Hospital of China Academy of Chinese Medical Sciences (WJEC-KT-2016-004-P001) and was registered at the Chinese Clinical Trials Registry (ChiCTR-INR-16009723) on 03 November 2016 (Check out at https://www.chictr.org.cn/indexEN.html for a more comprehensive overview).ResultsThe results showed that the improvement in JOA score at week 8 was significantly better in the Yishenyangsui granule group than in the placebo group (1.47 vs. 0.43; P < 0.001). …”
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Integrating univariate and multivariate stability indices for breeding clime-resilient barley cultivars by Ammar Elakhdar, Ahmed A. El-Naggar, Sally El-Wakeell, Anas H. Ahmed

“…Therefore, evaluating both yield performance and stability across diverse environments is essential in yield trials to identify high-yield potential and stable cultivars. …”
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Efficacy and cost-effectiveness of an ACT and compassion-based intervention for women with breast cancer: study protocol of two randomised controlled trials {1} by Inês A. Trindade, Andreia Soares, David Skvarc, Diogo Carreiras, Joana Pereira, Óscar Lourenço, Filipa Sampaio, Bruno de Sousa, Teresa C. Martins, Paula Boaventura, Joana Marta-Simões, Mind Project Team, Helena Moreira

“…Interventions based on Acceptance and Commitment Therapy (ACT) and compassion-based approaches show promise in improving adjustment and quality of life in people with cancer. …”
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An Analysis of the Impact of Digital Therapeutic Interventions on Attention and Working Memory in Children with Attention-Deficit/Hyperactivity Disorder: A Randomized Controlled Tr... by Seon-Chil Kim, Hojun Lee

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Comparative analysis of integer factorization algorithms by G. Kimsanova, R. Ismailova, R. Sultanov

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Safety and efficacy of oral cancer vaccine B440 in patients with PD-1/PD-L1 inhibitor-resistant advanced urothelial cancer: a study protocol for a phase 1 multicenter, open-label,... by Junya Furukawa, Yasumasa Kakei, Sae Murakami, Hiroshi Kita, Hideto Ueki, Takuto Hara, Jun Teishima, Nobuyuki Hinata, Hideaki Miyake, Masato Fujisawa, Toshiro Shirakawa

“…Secondary outcomes are the presence or absence of a response, the best overall response and PFS. Discussion If this trial shows B440 to be safe and effective, it may lead to a late phase randomized controlled trial in advanced urothelial cancer. …”
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Levilactobacillus brevis CD2 as a multifaceted probiotic to preserve oral health: results of a double-blind, randomized, placebo-controlled trial in healthy adults by Serena Altamura, Francesca Lombardi, Francesca Rosaria Augello, Antonella Barone, Mario Giannoni, Benedetta Cinque, Davide Pietropaoli

“…Results After four weeks, the probiotic group showed significant improvements in BoP and PI compared to baseline and placebo. …”
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Feasibility and safety of targeted focal microwave ablation of the index tumor in patients with low to intermediate risk prostate cancer: Results of the FOSTINE trial. by Nicolas Barry Delongchamps, Alexandre Schull, Julien Anract, Jean-Paul Abecassis, Marc Zerbib, Mathilde Sibony, Léa Jilet, Hendy Abdoul, Vincent Goffin, Michaël Peyromaure

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Evaluating the effects of time-restricted eating on overweight and obese women with polycystic ovary syndrome: A randomized controlled trial study protocol. by Hui Liu, Fuliang Shangguan, Fen Liu, Yu Guo, Huixi Yu, Hanbing Li, Yinhua Su, Zhongyu Li

“…Although an 8:00 a.m. to 16:00 p.m. time frame is reported to show positive results in most weight loss trial, its safety and efficacy in overweight and obese women with polycystic ovary syndrome (PCOS) is uncertain. …”
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Effects of specific inspiratory muscle training combined with whole-body endurance training program on balance in COPD patients: Randomized controlled trial. by Bilel Tounsi, Amal Acheche, Thierry Lelard, Zouhair Tabka, Yassine Trabelsi, Said Ahmaidi

“…We suggest that inspiratory muscle training might be introduced as additional training to pulmonary rehabilitation programs aimed at improving balance in COPD patients.<h4>Trial registration</h4>The trial registry name: Clinical Trials; Registration number: NCT04084405; URL: https://clinicaltrials.gov/ct2/show/NCT04084405.…”
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Comparison of the Effects of Articaine and Lidocaine Anesthetics on Blood Pressure after Maxillary Infiltration Technique: A Triple-Blind Randomized Clinical Trial by Amirhossein Moaddabi, Parisa Soltani, Maryam Zamanzadeh, Kamran Nosrati, Mojtaba Mollamirzaei, Mariangela Cernera, Gianrico Spagnuolo

“…In this randomized clinical trial, 102 patients were randomly assigned into two groups. …”
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