Suicidality and Illness Course Worsening in a Male Patient with Bipolar Disorder during Tamoxifen Treatment for ER+/HER2+ Breast Cancer by Claudia Carmassi, Francesco Pardini, Valerio Dell’Oste, Annalisa Cordone, Virginia Pedrinelli, Marly Simoncini, Liliana Dell’Osso

“…The clinical picture showed poor response to treatment trials based on various associations of mood-stabilising, antidepressants, and antipsychotic drugs. …”
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Efficacy of PD-1/PD-L1 Inhibitors versus Chemotherapy in Lung Cancer with Brain Metastases: A Systematic Review and Meta-Analysis by Xiaojun Yang, Yihong Zeng, Qinquan Tan, Zhihua Huang, Jun Jia, Guanming Jiang

“…We included 694 patients with BM from lung cancer from 11 randomized controlled trials. Statistical analysis showed that compared with chemotherapy, PD-1/PD-L1 inhibitors could significantly prolong OS (hazard ratio HR=0.75, 95%confidence interval 95%CI=0.51–0.99) and PFS (HR=0.65, 95%CI=0.51–0.80). …”
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Effect of home-based interventions on basic activities of daily living for patients who had a stroke: a systematic review with meta-analysis by Ping Qin, Canxin Cai, Xuan Chen, Xijun Wei

“…Objectives To investigate the effectiveness of home-based interventions in improving the ability to do basic activities of daily living in patients who had a stroke.Methods Randomised controlled trials were searched through MEDLINE, Embase and CINAHL from their inception to 31 December 2021. …”
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Effective treatment of severe acute pancreatitis and COVID-19 pneumonia with tocilizumab by Piotr Zielecki, Magdalena Kaniewska, Mariusz Furmanek, Tomasz Bulski, Grażyna Rydzewska

“…Food and Drug Association (FDA)-approved phase III randomised controlled trials on tocilizumab are ongoing [15]. We report the first (to date) case study of a patient with severe acute pancreatitis and COVID-19 pneumonia treated effectively with tocilizumab.…”
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African animal trypanocide resistance: A systematic review and meta-analysis by Keneth Iceland, Kasozi, Ewan, Thomas MacLeod, Susan, Christina Welburn

“…ISM (SMD = −0.41, 95% CI: −0.96, 0.14; I2 = 5%, P = 0.38) showed multiple cross-resistance. Clinical studies also showed evidence of multi-drug resistance on DA and ISM (RR = 1.01, 95% CI: 0.71–1.43; I2 = 46%, P = 0.16). …”
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Acupuncture for somatosensory deficits after stroke: a systematic review and meta-analysis by Shumeng Ren, Yuhang Chen, Yu Liu, Qiuyi Lv, Jing Peng, Lei Song, Yihuai Zou, Hua Zhang, Xing Chen

“…ObjectiveThis meta-analysis aimed to evaluate the randomized controlled trials (RCTs) of acupuncture for somatosensory deficits after stroke to provide the current best evidence for clinical practice.MethodsA systematic search was performed for eligible articles on the acupuncture for somatosensory deficits after stroke based on 14 databases. …”
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Is the Use of Tourniquets More Advantageous than Other Bleeding Control Techniques in Patients with Limb Hemorrhage? A Systematic Review and Meta-Analysis by Roberto Cirocchi, Dominica Prigorschi, Luca Properzi, Matteo Matteucci, Francesca Duro, Giovanni Domenico Tebala, Bruno Cirillo, Paolo Sapienza, Gioia Brachini, Sara Lauricella, Diletta Cassini, Antonia Rizzuto, Andrea Mingoli

“…Further research, including high-quality randomized controlled trials, is required, as well as awareness and education campaigns relating to proper tourniquet use in the prehospital setting.…”
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Investigating the Relationship between Automatic Negative Thoughts and Experiential Avoidance with Psychological Distress and the Mediating Role of Cognitive Emotion Regulation in... by Ahmad Alipour, Afsaneh Rahimi, Shahin Shadnia, Mitra Rahimi, Peyman Erfan Talab Evini, Sayed Masoud Hosseini, Babak Mostafazadeh

“…Additionally, experiential avoidance showed a significant positive relationship with maladaptive cognitive emotion regulation (β = 0.22, P < 0.01). …”
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Postoperative Harris Hip Score Versus Harris Hip Score Difference in Hip Replacement: What to Report? by Nikolai Ramadanov, Maximilian Voss, Robert Hable, Hassan Tarek Hakam, Robert Prill, Mikhail Salzmann, Dobromir Dimitrov, Roland Becker

“…Conclusion The present study showed that there is no relevant difference between reporting of the HHS only postoperatively or HHSdiff when comparing two hip replacement treatment groups in RCTs. …”
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System Evaluation of Buyang Huanwu Decoction in Treatment of Acute Ischemic Stroke by TANG Qiang, ZHANG Shiqiang, ZHU Luwen, TANG Yizhou, LI Hongyu

“…Patients with acute ischemic stroke with Qi deficiency and blood stasis syndrome differentiation in traditional Chinese medicine were included in the randomized controlled trials (RCTs), who were treated with Buyang Huanwu decoction. …”
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Assessment of Bowel Preparation Using Low-Volume Sulphate-Based Preparations in Comparison with Macrogols: A Multicenter, Randomized, Comparative Clinical Study of the 3rd Phase by Evgeny D. Fedorov, Viktor V. Veselov, Sergey V. Kashin, Ekaterina V. Tikhomirova, Alexey V. Veselov, Dmitry V. Zavyalov, Anne Kornowski, Tatyana Gorskaya, Magali Volteau, Thierry Ponchon

“…Despite the higher incidence of nausea in the OSS group, the patients showed significantly higher compliance with the OSS mode as compared to that of Macrogol.This study is registered with the ClinicalTrials.gov Registry of Clinical Trials, No. …”
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MECHANISMS AND CLINICAL PERSPECTIVES OF ALLERGEN-SPECIFIC IMMUNOTHERAPY by Leila Akhvlediani, Marina Izmailovich, Meruyert Gazaliyeva, Anna Skvortsova, Kanan Tanriverdiev

“…The "unified airways" concept emphasizes the interconnected nature of upper and lower airway inflammation, with ASIT showing promise in mitigating these effects. Materials and Methods: A systematic review included 51 articles published between 2013 and 2024, selected from databases such as PubMed and Scopus. …”
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Effects of proprioceptive training in the recovery of patients submitted to meniscus surgery: systematic review and meta-analysis by Song Jin, Xiaoxiao Liu, Di Zhang, Ju Wang, Tianyu Zhao, Jiang Ma, Huaimin Lu

“…Objective To evaluate the effects of proprioceptive training on rehabilitation of knee after arthroscopic partial meniscectomy (APM).Design PubMed, EMBASE, The Cochrane Library, Web of Science, China National Knowledge Infrastructure, Technology Periodical Database, WanFang Data and China Biology Medicine were searched until December 2021 for randomised controlled trials.Participants Patients who have undergone APM for meniscus injury caused by traumatic tear.Results A total of 9 studies with 453 patients were included in this study for meta-analysis, and 2/9 with high quality, 6/9 with moderate quality. …”
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Chimerism in Myeloid Malignancies following Stem Cell Transplantation Using FluBu4 with and without Busulfan Pharmacokinetics versus BuCy by Shatha Farhan, Michael Bazydlo, Klodiana Neme, Nancy Mikulandric, Edward Peres, Nalini Janakiraman

“…This will need to be examined in larger retrospective multicenter studies and prospective clinical trials.…”
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Evaluation and comparison of drying models in open sun drying and photovoltaic and LPG burner assisted hybrid solar drying system by Tubagus Rayyan Fitra Sinuhaji, Suherman Suherman, Hadiyanto Hadiyanto, Ardi Ardan, Sulistia Rahmawati

“…Results showed that HSD achieved superior performance, reducing drying times to 3–4 hours compared to 23 hours for OSD. …”
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Structure- and Ligand-Based Virtual Screening for Identification of Novel TRPV4 Antagonists by Atefeh Saadabadi, Linda Wilkman, Marja Rantanen, Ari-Pekka Koivisto, Outi M. H. Salo-Ahen

“…All tested compounds inhibited hTRPV4 at 30 µM, with compound Z1213735368 showing an IC₅₀ of 8 µM at a concentration of 10 µM. …”
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Systematic review and meta-analysis of propranolol in the prevention and treatment of post-traumatic stress disorder by Haipeng Li, Zhengrong Zhang, Shaojie Yang, Guoqi Zhu

“…The studies included randomized controlled trials (RCTs) investigating pharmacological treatments for PTSD. …”
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Factors Affecting Growth and Survival of <i>Salmonella</i> in Onion Extracts and Onion Bulbs by Emmanuel Kiplagat, Moazzameh Ramezani, Subas Malla, Luis Cisneros-Zevallos, Vijay Joshi, Alejandro Castillo

“…Onions exposed to blue, red, and white LED light during curing produced extracts with variable antimicrobial effects (<i>p</i> < 0.05), with those exposed to blue light showing the strongest inhibitory effect on red and white onions only. …”
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Preoxygenation strategies before intubation in patients with acute hypoxic respiratory failure: a network meta-analysis by Na Ye, Na Ye, Chen Wei, Jiaxiang Deng, Yingying Wang, Hongwen Xie

“…Model selection was based on the deviance information criterion (DIC).ResultsA total of 11 randomized controlled trials involving 2,874 patients were included. NIV preoxygenation significantly reduced the likelihood of SpO2 &lt;80% during intubation compared to COT (RR 0.28, 95% CI 0.070–0.71). …”
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Balancing CIK Cell Cancer Immunotherapy and PPAR Ligands: One Potential Therapeutic Application for CNS Malignancies by Kira Vordermark, JingJing Pu, Amit Sharma, Jarek Maciacyzk, Ingo G. H. Schmidt‐Wolf

“…ABSTRACT Background Cytokine‐induced killer (CIK) cell therapy has proven successful in clinical trials regarding glioblastoma. Equally important are the hints suggesting peroxisome proliferator‐activated receptors (PPARs) ligands being co‐expressed in the central nervous system (CNS). …”
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