Membrane Fouling and Chemical Cleaning in Three Full-Scale Reverse Osmosis Plants Producing Demineralized Water by Florian Beyer, Judita Laurinonyte, Arie Zwijnenburg, Alfons J. M. Stams, Caroline M. Plugge

“…TOC measurements and SEM showed that none of cleaning procedures applied could remove foulants completely from the membrane elements. …”
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Photobiomodulation in ocular therapy: current status and future perspectives by Hasan Chichan, Iftkhar Hamzah Aldujaly, Konstantinos Michalakis, Levent Kanal

“…Hence the future of photobiomodulation holds significant potential in medicine especially in ocular diseases characterized by progress in research, technology, and clinical trials.…”
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Different Strategies for the Treatment of Age-Related Macular Degeneration in China: An Economic Evaluation by Bin Wu, Jin Li, Houwen Lin, Haixiang Wu

“…One-way sensitivity analysis showed considerably influential factors, such as utility values and effectiveness data. …”
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A Meta-Analysis of Statin Use and Risk of Hepatocellular Carcinoma by Yikai Wang, Wenjun Wang, Muqi Wang, Juanjuan Shi, Xiaoli Jia, Shuangsuo Dang

“…Conclusion. Our meta-analysis shows that the use of statins is associated with a lower risk of liver cancer.…”
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The impact of dietary patterns on gut microbiota for the primary and secondary prevention of cardiovascular disease: a systematic review by Junwen Yu, Yue Wu, Zheng Zhu, Hongzhou Lu

“…Conclusions Different dietary patterns showed distinct impacts on gut microbiota composition. …”
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Fortifying plant fortresses: siderophores in defense against Cercospora leaf spot disease in Vigna radiata L. by Anushree Kamath, Abhishek Sharma, Arpit Shukla, Arpit Shukla, Arpit Shukla, Paritosh Parmar, Dhara Patel

“…Similarly, PR10 expression showed moderate upregulation in S15 and significantly higher levels in SP15, reflecting enhanced pathogen defense. …”
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Endovascular therapy versus best medical care for acute ischemic stroke with distal medium vessel occlusion: a systematic review and meta-analysis by Ziyue Wang, Jiacheng Li, Qianqian Kong, Hao Yan, Yi Zhang, Xirui Zhou, Zhiyuan Yu, Hao Huang, Xiang Luo

“…Those patients with PCA occlusion showed no significant difference in functional outcomes. …”
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Clinical characteristics of and growth hormone treatment effects on short stature with type 1 insulin-like growth factor receptor (IGF1R) gene alteration by Yuki Kawashima-Sonoyama, Keisuke Wada, Kei Yamamoto, Masanobu Fujimoto, Noriyuki Namba, Takeshi Taketani

“…Promoting genetic testing and clinical trials on GH administration for this condition is recommended.…”
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The efficacy of platelet-rich plasma in ankle disease: a systematic review and meta-analysis by Qixin Ding, Xu Wang, Yurong Liu, Yuefang Li, Di Zhang, Heling Wang, Shenhong Ma, Qiaohua Han, Weisheng Zhuang

“…Regarding the AOFAS score, a meta-analysis that included five randomized controlled trials (each study extracted the score results at the last follow-up time) showed no statistically significant differences between the platelet-rich plasma intervention group and the control group, and there was a great deal of heterogeneity in the results, with subgroup analyses based on disease type. …”
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Absence of Standard Modifiable Risk Factors in Middle Eastern Patients with Atherosclerotic Cardiovascular Disease. The Jordan Absence of Standard Modifiable Risk Factors (SMuRF-Le... by Hammoudeh AJ, Aldalal’ah M, Smadi EA, Alrishoud D, Alomari A, Alkhawaldeh M, Rizik A, Okour MF, Araydah M

“…SMuRF-less patients were younger, had less comorbid disease, received less secondary prevention pharmacotherapy and had higher rate of one year mortality than those with SMuRFs.Clinical Trials: The study is registered with ClinicalTrials.gov, unique identifier number NCT06199869.Keywords: atherosclerotic cardiovascular disease, standard modifiable risk factors, SMuRF-less patients, Middle Eastern patients…”
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Selection of In Vivo Relevant Dissolution Test Parameters for the Development of Cannabidiol Formulations with Enhanced Oral Bioavailability by Nathan Koch, Quentin Bourcy, Olivier Jennotte, Patrice Chiap, Anna Lechanteur, Jean-Michel Cardot, Brigitte Evrard

“…<b>Background:</b> Cannabidiol (CBD) shows interesting therapeutic properties but has yet to demonstrate its full potential in clinical trials partly due to its low solubility in physiologic media. …”
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Dual Inhibition of CDK4/6 and CDK7 Suppresses Triple‐Negative Breast Cancer Progression via Epigenetic Modulation of SREBP1‐Regulated Cholesterol Metabolism by Yilan Yang, Jiatao Liao, Zhe Pan, Jin Meng, Li Zhang, Wei Shi, Xiaofang Wang, Xiaomeng Zhang, Zhirui Zhou, Jurui Luo, Xingxing Chen, Zhaozhi Yang, Xin Mei, Jinli Ma, Zhen Zhang, Yi‐Zhou Jiang, Zhi‐Min Shao, Fei Xavier Chen, Xiaoli Yu, Xiaomao Guo

“…This suggests a new treatment approach for TNBC by simultaneously targeting CDK4/6 and CDK7, warranting additional clinical trials.…”
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PNPO‐Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β‐Catenin Pathway by Zhendong Deng, Shanliang Sun, Nian Zhou, Yumeng Peng, Long Cheng, Xichao Yu, Yuxia Yuan, Mengjie Guo, Min Xu, Yuexin Cheng, Fan Zhou, Nianguang Li, Ye Yang, Chunyan Gu

“…In addition, the experiments showed its efficacy in mouse models. Eltrombopag inhibited the growth of MM cells and reduced bone lesions by disrupting the interaction between PNPO and DVL3, as supported by preliminary clinical trials. …”
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Probiotics Reduce Postoperative Infections in Patients Undergoing Colorectal Surgery: A Systematic Review and Meta-Analysis by Peng Cheng Liu, Yu Ke Yan, Yu Jing Ma, Xiang Wen Wang, Jie Geng, Man Cai Wang, Feng Xian Wei, Ya Wu Zhang, Xiao Dong Xu, You Cheng Zhang

“…According to the results, only randomized controlled trials that compared the efficacy of probiotics on patients with colorectal resection were included for meta-analysis. …”
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Calpain 2 regulates IL-1α secretion and inhibits tumor development via modulating calpain 1 expression in the tumor microenvironment by Zuhairah Binte Hanafi, Yu Mei, Huey Yee Teo, Ying Zhu, Chew Chin Yong Lionel, Jing Wen Chiu, Jinhua Lu, Haiyan Liu

“…Tumor-promoting inflammation significantly impacts cancer progression, and targeting inflammatory cytokines has emerged as a promising therapeutic approach in clinical trials. Interleukin (IL)-1α, a member of the IL-1 cytokine family, plays a crucial role in both inflammation and carcinogenesis. …”
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Classifying vocal responses of broilers to environmental stressors via artificial neural network by T. Lev-ron, Y. Yitzhaky, I. Halachmi, S. Druyan

“…Additionally, the study evaluated the impact of majority vote decision-making across the three ANN model sizes, showing improvement in mean average precision (mAP), particularly for models with shorter audio inputs. …”
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Safety of Dupilumab Therapy for Atopic Dermatitis during Pregnancy: A Systematic Review and Meta-analysis by Verónica Sánchez-García, Eva de-Miguel-Balsa, José-Manuel Ramos-Rincón, Isabel Belinchón-Romero

“…The sensitivity analyses showed no significant differences in weighted prevalences. …”
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The Impact of Creatine Supplementation on Physical Performance, Cognitive Functions, and Safety – A Literature Review by Adam Sobiński, Matylda Czerwonka, Zuzanna Kościuszko, Katarzyna Kurza, Silvia Ciraolo, Julianna Podolec, Agnieszka Kulczycka-Rowicka, Katarzyna Lesiczka-Fedoryj, Joanna Wojda, Anna Walczak

“…Research Materials and Methods: The study is based on clinical trials, meta-analyses, and systematic reviews from the past decade. …”
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Continuous Inhibition of Sonic Hedgehog Signaling Leads to Differentiation of Human-Induced Pluripotent Stem Cells into Functional Insulin-Producing β Cells by Song Lee, Jae Hyun Joo, Ju Yun Oh, Eun Ha Seo, Yang Hee Kim, Eunsung Jun, In Kyong Shim, Song Cheol Kim

“…Images of the 2D culture showed that IPCs formed spheroids from day 5 and continuously secreted insulin. …”
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The Potential of Virtual Reality for Inducing Neuroplasticity in Children with Amblyopia by María B. Coco-Martin, David P. Piñero, Luis Leal-Vega, Carlos J. Hernández-Rodríguez, Joaquin Adiego, Ainhoa Molina-Martín, Dolores de Fez, Juan F. Arenillas

“…Several clinical researches on this issue have been conducted, showing the potential of promoting visual acuity, contrast sensitivity, and stereopsis improvement. …”
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