Antihypertensive strategies for the prevention of secondary stroke: a systematic review and meta-analysis by ChunQi Wang, Ling Feng, ShuangYan Tu, Dan Wei, Rui Wang, ZhiQiang Deng, YiPing Luo

“…Methods A systematic search of PubMed, Embase, Cochrane Central Register of Controlled Trials, and Web of Science databases was conducted through January 12, 2024. …”
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Effect of proprioceptive neuromuscular facilitation on patients with chronic ankle instability: A systematic review and meta-analysis. by Yikun Yin, Jialin Wang, Qihan Lin, Yinghang Luo, Yongsheng Liu, Junzhi Sun

“…<h4>Results</h4>① A total of 12 randomized controlled trials were included, encompassing 405 patients with Chronic Ankle Instability, demonstrating a generally high methodological quality of the literature.② Meta-analysis results indicate that compared to the control group, Proprioceptive Neuromuscular Facilitation (PNF) significantly enhanced the balance ability of patients with Chronic Ankle Instability as measured by the Y Balance Test (YBT) (Weighted Mean Difference (WMD) = 3.61, 95% CI [2.65, 4.56], z = 7.42, P<0.001) and the Star Excursion Balance Test (SEBT) (WMD = 5.50, 95% CI [3.80, 7.19], z = 6.36, P<0.001), with improvement in all eight directions of SEBT balance ability surpassing that of the control group (P<0.05); muscle strength around the ankle (SMD) = 0.19, 95% CI [0.03, 0.36], z = 2.26, P = 0.024), with both Plantar flexion and Dorsal flexion muscle strength improvements exceeding those of the control group (P<0.05); Visual Analog Scale (VAS) (WMD = -1.39, 95% CI [-1.72, -1.06], z = 8.23, P<0.001); Ankle instability questionnaire (WMD = 2.91, 95% CI [1.92, 3.89], z = 5.78, P<0.001).③Descriptive analysis results showed that the differences in Inversion Joint Position Sense and Dorsiflexion range of motion between the PNF and control groups were not statistically significant (P>0.05), however, the effects of PNF training persisted for a certain period even after cessation of treatment.…”
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The effect of exercise intervention on inhibitory function in obese and overweight children and adolescents: a systematic review and meta-analysis by Aona Chen, Chenggen Guo, Shuhua Qu

“…Results The analysis included 24 randomized controlled trials (RCTs) with a total of 1,247 participants. …”
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Crossroad of Tradition and Innovation – The Application of Lactic Acid Fermentation to Increase the Nutritional and Health-Promoting Potential of Plant-Based Food Products – a Revi... by Anna Maria Ogrodowczyk, Natalia Drabińska

“…However, still more clinical trials evaluating the effect of their consumption on the human health are in demand.…”
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Cricoid chondroma presenting as upper airway obstruction: A report of a rare case by Samuel Sisay Hailu, MD, Eyoel Degafu, MD, Tequam Debebe, MD, Yonas Shumiye, MD, Bizunesh Dires, MD, Bethlehem Tesfasilassie Kibrom, MD

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Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway by Xin-peng Fan, Ji-rong Wang, Si-yu Chen, Xiao-ran Li, Jin-long Cao, Hua-bin Wang, Li-yun Ding, Tuan-jie Che, Li Yang

“…Analysis of multiple BLCA datasets consistently showed the group with reduced PROS1 expression was linked to cancer-promoting pathways, more aggressive characteristics, and a greater chance of responding positively to immunotherapy. …”
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Advancing Multiple Myeloma Immunotherapy: A Review of Chimeric Antigen Receptor T-Cell and Bispecific T-Cell Engagers Cell Therapies in Revolutionizing Treatment by Rahul Navab, Pragyat Futela, Verkha Kumari, Jayesh Valecha, Ramansh Bandhu Gupta, Rohit Jain

“…These therapies exhibit impressive efficacy in clinical trials, leading to FDA approvals for specific MM patient populations. …”
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Immunogenicity and safety of the 15-valent pneumococcal conjugate vaccine, a systematic review and meta-analysis by Gernot Wagner, Gerald Gartlehner, Kylie Thaler, Dominic Ledinger, Johanna Feyertag, Irma Klerings, KM Saif-Ur-Rahman, Declan Devane, Kate Olsson, Karam Adel Ali, Sabine Vygen-Bonnet, Heini Salo, Dace Zavadska, Marta Grgič Vitek, Marje Oona, Robert Cunney, David Tuerlinckx, Frederikke Kristensen Lomholt, Isolde Sommer

“…We identified 20 randomized controlled trials (RCTs). A meta-analysis of six RCTs in infants showed that PCV15 was non-inferior compared with PCV13 for 12 shared serotypes. …”
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Glutamate enhances shrimp antibacterial ability by boosting its cellular immunity by Lei Ma, Wenyong Jiang, Zhiyao Lu, Yanmei Tong, Qingyun Liu, Zhonghua He, Xiuli Chen, Yongzhen Zhao, Fan Wang

“…In this study, we demonstrate a correlation between plasma glutamate increased the total hemocyte counts in shrimp within two hours, an effect that was reversed by co-injection with a Grik2 inhibitor. Subsequent feeding trials showed that incorporating 0.25 % glutamate into shrimp diets significantly raised the glutamate concentration in muscle tissue, resulting in a 7 % increase in glutamate content. …”
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In Vivo Tracking of Systemically Administered Allogeneic Bone Marrow Mesenchymal Stem Cells in Normal Rats through Bioluminescence Imaging by Juan Cao, Shike Hou, Hui Ding, Ziquan Liu, Meijuan Song, Xiaojing Qin, Xue Wang, Mengyang Yu, Zhiguang Sun, Jinyang Liu, Shuli Sun, Peixin Xiao, Qi Lv, Haojun Fan

“…Recently, mesenchymal stem cells (MSCs) are increasingly used as a panacea for multiple types of disease short of effective treatment. Dozens of clinical trials published demonstrated strikingly positive therapeutic effects of MSCs. …”
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Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential by Lyca R. da Fonseca, Rafaele de A. Rodrigues, Aline de S. Ramos, Jefferson D. da Cruz, José Luiz P. Ferreira, Jefferson Rocha de A. Silva, Ana Claudia F. Amaral

“…Furthermore, the Brazilian Regulatory Health Agency Datavisa, Medicines and Healthcare Products Regulatory Agency of the United Kingdom, and the European Medicines Agency websites were consulted. The results showed that Passiflora species have health benefits but clinical trials are still scarce. …”
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Lutein Leads to a Decrease of Factor D Secretion by Cultured Mature Human Adipocytes by Yuan Tian, Aize Kijlstra, Johan Renes, Martin Wabitsch, Carroll A. B. Webers, Tos T. J. M. Berendschot

“…Complement plays an important role in the pathogenesis of age related macular degeneration (AMD) and trials are currently being conducted to investigate the effect of complement inhibition on AMD progression. …”
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Production technology of poultry sausage-1: the studies on the quality of chemical, microbiological and organoleptic by Nazif Anıl, Yusuf Doğruer, Ümit Gürbüz, Semra Kayaardı, Abdullah Keleş

“…It was detected that the number of total microorganisms and Lactobacillus species increased among aging and storage while coliform bacteria and yeasts-moulds showed significant and Staphylococcus - micrococcus species showed slight decreasing. …”
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Brief Acceptance and Commitment Therapy for Fibromyalgia: Feasibility and Effectiveness of a Replicated Single-Case Design by María Camino Gómez-Pérez, Azucena García-Palacios, Diana Castilla, Irene Zaragozá, Carlos Suso-Ribera

“…The remaining patients showed more modest improvements which affected a reduced number of outcomes. …”
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First‐in‐Man Study of a Novel Peripheral Plaque Atherectomy Device by Hui Wang, Dikang Pan, Shijun Cui, Zhu Tong, Xixiang Gao, Yongquan Gu, Jianming Guo, Lianrui Guo

“…Larger‐scale trials are needed to confirm these outcomes.…”
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Controversial Roles of Regenerating Family Proteins in Tissue Repair and Tumor Development by Luting Yu, Qingyun Wu, Shenglong Jiang, Jia Liu, Junli Liu, Guoguang Chen

“…Successively, short peptides derived from Reg3δ and Reg3α have been employed in clinical trials, showing favorable therapeutic effects in patients with type I and type II diabetes. …”
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How Breathing Exercises Influence on Respiratory Muscles and Quality of Life among Patients with COPD? A Systematic Review and Meta-Analysis by Ruisheng Yun, Yiwen Bai, Yan Lu, Xubo Wu, Shin-Da Lee

“…However, breathing exercises showed no significant improvements on the QoL of patients with COPD.…”
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Open-Label Fosmetpantotenate, a Phosphopantothenate Replacement Therapy in a Single Patient with Atypical PKAN by Yiolanda-Panayiota Christou, George A. Tanteles, Elena Kkolou, Annita Ormiston, Kostas Konstantopoulos, Maria Beconi, Randall D. Marshall, Horacio Plotkin, Kleopas A. Kleopa

“…Conclusions. Fosmetpantotenate showed promising results in a single PKAN patient and should be further studied in controlled trials.…”
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AGENTS USED FOR ENAMEL REMINERALISATION AND REDUCING DENTIN HYPERSENSITIVITY: A COMPREHENSIVE REVIEW by N.V. Yanko

“…Most novel fluoride compounds showed higher remineralising and desensitising abilities as compared to conventional fluorides. …”
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Long-Term Safety and Efficacy of Percutaneous Left Atrial Appendage Closure with the LAmbre Device by Guangji Wang, Bin Kong, Yu Liu, He Huang

“…However, further large-scale trials might be required to confirm our findings.…”
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