Comparative efficacy and safety of first-line neoadjuvant therapy for early-stage non-small cell lung cancer based on immune checkpoint inhibitor therapy: a systematic review and n... by Linfeng Wang, Guangda Zheng, Yue Hu, Ayidana Maolan, Yue Luo, Yue Li, Rui Liu

“…Methods We searched PubMed, EMBASE, Cochrane Library, ClinicalTrials.go and randomised controlled trials (RCTs) from major international conferences for literature related to neoadjuvant immunotherapy combinations published as first-line treatment options for non-small cell lung cancer from the start of the library to 20 February 2024, and performed a systematic review and network meta-analysis. …”
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Effectiveness of cupping therapy for musculoskeletal pain: an umbrella review by Mohamed Magdy ElMeligie, Amr M. Yehia, Mahmoud Hamada Mohamed, Manna Mahmoud, Mohamed N. AlKholui, Ghada I. Mohamed

“…Most reviews included trials of low quality (i.e., high risk of bias). …”
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Systematic Review and Meta-Analysis of the Evaluation of the Efficacy of Manipulation and Cervical Traction in the Treatment of Radical Cervical Spondylosis by Jianquan Chen, Rongbin Chen, Yong Li, Maoshui Chen, Zhouming Lv, Haobin Zeng, Qiang Lian

“…The literature related to this study was included according to selective criteria and inhibitory elimination criteria, and valuable information was selected for statistical analysis, resulting in a total of 11 randomized controlled trials with 994 subjects. Results. The short-term efficacy of manual treatment for CSR was superior to that of cervical traction alone (P<0.05); subgroup analysis showed that the short-term efficacy of pulling or rotational manipulation was superior to that of cervical traction (P<0.05). …”
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The combination treatment of RC48 and STAT3 inhibitor acts as a promising therapeutic strategy for basal bladder cancer by Jingxian Li, Kun Shan, Wei Huang, Qiang Su, Yuanjiong Qi, Zhihong Zhang, Jianqiang Zhu, E. Du

“…In addition, luminal cells showed higher sensitivity to RC48 than basal cells. …”
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Fosaprepitant as combination therapy to prevent chemotherapy-induced vomiting in children: a meta-analysis by Yanshuo Shi, Yanshuo Shi, Yuanyuan Yue, Yuanyuan Yue, Yue Zhang, Guoxun Pang

“…ObjectiveTo systematically evaluate the clinical efficacy and safety of fosaprepitant combined with 5-hydroxytryptamine 3 receptor antagonists (5-HT3RA) (with or without dexamethasone) on the chemotherapy-induced vomiting in pediatric cancer patients.MethodsPubMed, Embase, Cochrane Library, China Journal full-text database (CNKI), Wanfang data knowledge service platform (Wanfang) and VIP Chinese sci-tech Journal full-text database (VIP) were searched by computer (retrieval time from database establishment to Apr. 2024), randomized controlled trials (RCTs) and cohort studies about fosaprepitant and 5-HT3RA with or without dexamethasone (observation group) versus 5-HT3RA, with or without dexamethasone, as the control group for chemotherapy-induced vomiting were collected, after data extraction and quality evaluation, meta-analysis was carried out by Rev Man 5.3 software.ResultsA total of 731 patients were included in 7 trials. …”
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High-intensity statin therapy in patients with chronic kidney disease: a systematic review and meta-analysis by Jing Wang, Ling Wu, Yu-Ling Yan, Bo Qiu, Song-Bai Deng, Xiao-Dong Jing, Jian-Lin Du, Ya-Jie Liu, Qiang She

“…Objective To evaluate the efficacy and safety of high-intensity statin therapy in patients with chronic kidney disease (CKD).Design A systematic review and meta-analysis.Data sources Randomised controlled trials (RCTs) comparing high-intensity statin therapy (atorvastatin 80 mg or rosuvastatin 20/40 mg) with moderate/mild statin treatment or placebo were derived from the databases (PubMed, Embase, Ovid, the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, and ISI Web of Knowledge).Outcome measure Primary end points: clinical events (all-cause mortality, stroke, myocardial infarction and heart failure); secondary end points: serum lipid, renal function changes and adverse events.Results A total of six RCTs with 10 993 adult patients with CKD were included. …”
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Can we prevent poststroke cognitive impairment? An umbrella review of risk factors and treatments by Clare Flach, Abdel Douiri, Vibhore Prasad, Majed Obaid, Iain Marshall

“…Physical activity and cognitive rehabilitation interventions showed evidence of enhancing cognitive function; however, we could not recommend a change in practice yet, due to lack of strong evidence.PROSPERO registration number CRD42018096667.…”
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Artificial intelligence methods applied to longitudinal data from electronic health records for prediction of cancer: a scoping review by Victoria Moglia, Owen Johnson, Gordon Cook, Marc de Kamps, Lesley Smith

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The Efficacy of Parenteral Nutrition and Enteral Nutrition Supports in Traumatic Brain Injury: A Systemic Review and Network Meta-Analysis by Yan Qin, Maoxia Liu, Fengbao Guo, Du Chen, Peng Yang, Xionghui Chen, Feng Xu

“…All randomized controlled trials (RCTs) which compared the effects of different nutritional supports on clinical outcomes and nutritional indicators in patients with TBI were included. …”
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Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer’s Disease by Lenka Hromadkova, Saak Victor Ovsepian

“…Herein, we review recent data showing the occurrence of tau-reactive antibodies in the brain and peripheral circulation and discuss their origin and significance in tau clearance. …”
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Rare epithelial gastric cancers: a review of the current treatment knowledge by Angelica Petrillo, Margaret Ottaviano, Luca Pompella, Emilio Francesco Giunta, Pasquale Pisapia, Gianpaolo Marte, Andrea Tufo, Sara Di Lorenzo, Jessica Orefice, Chiara Miceli, Umberto Malapelle, Bruno Daniele, Ferdinando De Vita

“…Gastric cancer (GC), one of the tumours with the highest mortality worldwide, is not a homogeneous disease, showing different features according to location, macroscopic aspect, histotype and molecular alterations. …”
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Gut Microbiome in Obsessive Compulsive Disorder: Potential of Probiotics as an Adjuvant Therapy by Grace Yong-En Kong, Vengadesh Letchumanan, Loh Teng-Hern Tan, Jodi Woan-Fei Law

“…In vivo animal studies showed that probiotics can potentially improve OCD symptoms. …”
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Acupuncture Efficacy on Acute Stroke Patients:A Meta-analysis by Jiaqing LIU, Tongyan LIU, Yun XIANG, Ning ZHAO, Hong ZHANG

“…The Stata 12.1 software was used for meta-analysis and the GRADE-profile was used to assess the outcome.Results:Eleven trials that represented 1,087 participants were included. …”
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An Update on the Controversies in Anemia Management in Chronic Kidney Disease: Lessons Learned and Lost by Geoffrey Teehan, Robert L. Benz

“…We review three recent randomized trials in anemia in CKD: CHOIR, CREATE, and TREAT. …”
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Long-Term Use of Ruxolitinib in an AML Patient with Posttransplant Steroid Refractory GVHD by Philip T. Sobash, Achuta K. Guddati, Vamsi Kota

“…Of the available literature showing ruxolitinib utilization for srGVHD, most cases lead to resolution and eventual discontinuation. …”
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An Anaplastic Lymphoma Kinase-positive Inflammatory Myofibroblastic Tumor with Rapidly Acquired Resistance to First-line Anaplastic Lymphoma Kinase Inhibitor: A Case and Literature... by Shu-Cheng Wu, Hsing-Wu Chen

“…Early phase clinical trials have demonstrated the efficacy of ALK inhibitors in the treatment of IMTs. …”
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Sequence Learning and Chunk Stability in Guinea Baboons (Papio papio) by Laure Tosatto, Joël Fagot, Arnaud Rey

“…Eighteen Guinea baboons (Papio papio) repeatedly produced the same fixed sequence of nine movements during 1,000 trials by pointing to a moving target on a touch screen. …”
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Acupuncture in the Treatment of a Female Patient Suffering from Chronic Schizophrenia and Sleep Disorders by Peggy Bosch, Sabina Lim, Sujung Yeo, Sook-Hyun Lee, Heike Staudte, Maurits van den Noort

“…In sum, this study showed that acupuncture might be beneficial in the treatment of sleep disorders in patients suffering from chronic schizophrenia, but future, large, randomized (placebo), controlled, clinical trials are needed in order to replicate the present preliminary findings.…”
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Warm and humid environment induces gut microbiota dysbiosis and bacterial translocation leading to inflammatory state and promotes proliferation and biofilm formation of certain ba... by Yinrui Guo, Jianlang He, Shaojie Li, Shiqi Zou, Haiting Zhang, Xin Yang, Jian Wang

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Biological control of Schistocerca gregaria and Locusta migratoria migratorioides using Entomopathogenic bacteria by Jihan Muhammad, Zeinab Fathy, Saad Moussa

“…In field trials, X. nematophila BA2 exhibited the highest nymphal mortality rate of 88.70% at 7 days after spraying. …”
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