Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management by Laura M. S. Seeber, Ronald P. Zweemer, René H. M. Verheijen, Paul J. van Diest

“…Preliminary data shows encouraging results for these agents. Further work is needed to identify selective HIF-1 inhibitors and to translate these into clinical trials.…”
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The role of anti-inflammatory diets and supplementation in metabolic syndrome and symptom remission in adults with schizophrenia: a systematic review by Elizabeth Suschana, Thea Anderson, Catriona Hong, Arun Narikatte, Jillian Silverberg, Manu Suresh Sharma

“…Prebiotic, probiotic, and fish oil supplementation showed improvements in metabolic markers. Fish oil and vitamin D supplementation demonstrated symptom remission in some trials.ConclusionIt is important to consider that people with schizophrenia may experience common external barriers that hinder adherence to dietary interventions. …”
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Vitamin D Supplementation Ameliorates Metabolic Dysfunction in Patients with PCOS: A SystematicReview of RCTs and Insight into the Underlying Mechanism by Shan Guo, Reshef Tal, Haoyu Jiang, Tao Yuan, Ying Liu

“…Literature research was conducted in Pubmed, Embase, Web of Science, Clinical Trials, and Cochrane Library to identify relevant randomized controlled trials (RCTs) up to March 2020. …”
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High-Flow Nasal Cannula in Hypercapnic Respiratory Failure: A Systematic Review and Meta-Analysis by Yongkang Huang, Wei Lei, Wenyu Zhang, Jian-an Huang

“…We used the Cochrane risk-of-bias tool and the Newcastle–Ottawa Quality Assessment Scale to assess the quality of randomized controlled trials (RCTs) and cohort studies, respectively. Data from eligible trials were extracted for the meta-analysis. …”
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Cardiovascular safety of Janus kinase inhibitors in inflammatory bowel disease: a systematic review and network meta-analysis by Huibin Yang, Ting An, Yuxuan Zhao, Xiaojing Shi, Bangmao Wang, Qingyu Zhang

“…P-score was applied to rank interventions.Results A total of 26 trials involving 10,537 IBD patients were included, and results showed no significantly increased risk of MACE, VTE and CVE was associated with JAKinibs. …”
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Comparison of the efficacy of seven non-surgical methods combined with mechanical debridement in peri-implantitis and peri-implant mucositis: A network meta-analysis. by Yingjie Bai, Shengao Qin, Bingshuai Lu, Weiyi Wang, Guowu Ma

“…We employed a frequency random effects network meta-analysis model to combine the effect sizes of the trials using standardized mean difference (SMD) and 95% confidence intervals (CIs). …”
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Identifying P100 and N170 as electrophysiological markers for conscious and unconscious processing of emotional facial expressions by Lennard Herzberg, Julia Schräder, Julia Schräder, Han-Gue Jo, Ute Habel, Ute Habel, Lisa Wagels, Lisa Wagels

“…While varying primer presentation time (16.7 ms for unconscious; 150 ms for conscious perception), either congruent or incongruent primer / target emotions were displayed.ResultsThe N170 was significantly larger in trials with conscious compared to unconscious primer presentation, while the P100 showed opposite results displaying higher amplitudes in unconscious versus conscious trials. …”
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L’essai by Franck Renucci, David Galli

“…What makes this paper different is that it shows how researchers today are bereft of biological, psychological, and social guidance. …”
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Mobiliser son réseau en justice à Dijon à la fin du Moyen Âge by Rudi Beaulant

“…The criminal archives of the Dijon town hall are full of information, investigations and trials brought against people under its jurisdiction throughout the 15th century. …”
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The Effect of Locomotor Training on Gait Parameters in Pediatric Patients with Cerebral Palsy: a Systematic Review and Meta-analysis by Emilija Strazdaitė, Dovilė Kielė

“…A systematic review with meta-analysis was conducted based on the results of the PubMed (MEDLINE) and the CINAHL Ultimate (EBSCOhost) searches for randomized clinical trials. Results. Fifteen eligible randomized clinical trials involving 375 pediatric patients with cerebral palsy were included. …”
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Safety and efficacy of dual versus triple antithrombotic therapy (DAT vs TAT) in patients with atrial fibrillation following a PCI: a systematic review and network meta-analysis by Abdulaali R Almutairi, Renad M Altoukhi, Reema A Alshouimi, Shahad M Al Rammah, Mohammed Y Alzahrani, Abdulmajeed M Alshehri, Osamah M Alfayez, Majed S Al Yami, Omar A Almohammed

“…However, there are no head-to-head trials comparing the DAT regimens to each other. We aimed to compare the efficacy and safety of DAT regimens using a network meta-analysis (NMA) approach.Design A systematic review and NMA of randomised clinical trials.Methods We conducted a systematic literature review to identify relevant randomised clinical trials and performed a Bayesian NMA for International Society on Thrombosis and Haemostasis (ISTH) major or clinically relevant non-major (CRNM) bleeding, all-cause mortality, stroke, myocardial infarction (MI) and stent thrombosis outcomes. …”
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Patent Foramen Ovale Closure for Treating Migraine: A Meta-Analysis by Yu Zhang, Haijiao Wang, Ling Liu

“…In total, three randomized controlled trials, one pooled study, and eight retrospective case series including 1,165 participants were included in the meta-analysis. …”
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Mirror therapy to reduce phantom limb pain. Systematic review by Jesús Sánchez Lozano, Sandra Martínez Pizarro

“…All studies showed safety, and no major side effects occurred. …”
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A Systematic Review and Network Meta-Analysis on the Efficacy of Medications in the Treatment of Chronic Idiopathic Constipation in Japan by Atsushi Nakajima, Ayako Shoji, Kinya Kokubo, Ataru Igarashi

“…The present systematic review and meta-analyses included 1460 patients in 6 randomized clinical trials: 2 on linaclotide, 3 on elobixibat, 2 on lubiprostone, and 1 on lactulose. …”
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A systematic review of the effect of personal health records on patient activation by Irina Osovskaya, Ann Blandford, Henry WW Potts

“…Conclusion Most studies showed little impact on activation, but one study found a large effect. …”
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Efficacy of fish oil supplementation on metabolic dysfunction-associated steatotic liver disease: a meta-analysis by Like Zhou, Dongmei Sun, Houqiao Bai

“…Outcomes measured were aspects of liver injury, lipid profile, insulin resistance, anthropometric measurements, and more.ResultsSeven randomized controlled trials (RCTs) involving 439 participants were incorporated into the analysis. …”
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Meta-analysis on the entomological effects of differentially treated ITNs in a multi-site experimental hut study in sub-Saharan Africa by Natalie Lissenden, John Bradley, Benjamin Menze, Charles Wondji, Constant Edi, Benjamin Koudou, Raphael N’Guessan, Koama Bayili, Abdoulaye Diabaté, Njelembo Mbewe, Basiliana Emidi, Jacklin Mosha, Alphaxard Manjurano, Graham Small, Welbeck Oumbouke, Sarah Jane Moore, Derric Nimmo, Janneke Snetselaar

“…The combined data from these trials were analysed in a meta-analysis, and odds ratios for the effect of the different net designs on mortality and blood-feeding were estimated using mixed effects logistic regression. …”
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DEPEND study protocol: early detection of patients with pancreatic cancer – a pilot study to evaluate the utility of faecal elastase-1 and 13C-mixed triglyceride breath test as scr... by Christopher D Byrne, Sam Wilding, Paul Remi Afolabi, Declan McDonnell, Victoria Goss, Jocelyn Walters, Zaed Z Hamady

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Components of cognitive–behavioural therapy for mitigating core symptoms in attention-deficit hyperactivity disorder: a systematic review and network meta-analysis by Sayo Hamatani, Kazuki Matsumoto, Yoshihiko Kunisato, Yoshifumi Mizuno

“…This review included only randomised controlled trials.Findings 43 trials with 3817 participants were included in the network meta-analyses. …”
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A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer by Li-Li Xie, Zhi-Hong Xu, Deng-Hui Wei, Chun-Sen Xu

“…More randomized trials are needed for further study due to limited randomized trials.…”
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