Fecal Microbiota Transplantation as Therapy for Treatment of Active Ulcerative Colitis: A Systematic Review and Meta-Analysis by Xiaolei Liu, Yan Li, Kaichun Wu, Yongquan Shi, Min Chen

“…Randomized controlled trials (RCTs) recruiting adults with active UC, which compared FMT with controls, were eligible. …”
Get full text

Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system by Jingrong Yang, Mengfan You, Jingxin Wang, Rongfei Sun, Lili Han, Xiaonan Liu, Kaibin Niu, Kaidi Xing, Juanping Sun, Wenge Su, Yifei Wang

“…The Weibull distribution analysis showed a median onset time of 5 days for intravenous administration compared to 74 days for oral administration. …”
Get full text

Diagnostic Accuracy of Procalcitonin for Bacterial Infection in Liver Failure: A Meta-Analysis by Xinchun He, Liang Chen, Haiou Chen, Yuqing Feng, Baining Zhu, Caixia Yang

“…In this study, we included prospective observational studies or randomized controlled trials on PCT. The quality of the studies was evaluated using the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool. …”
Get full text

PARP inhibitor‐based treatment in metastatic, castration‐resistant prostate cancer (mCRPC): A systematic review and meta‐analysis by Michela Roberto, Mattia Alberto Di Civita, Daniele Marinelli, Andrea Torchia, Nertila Cara, Giulia Maltese, Iolanda Speranza, Daniele Santini

“…Abstract Background We present a systematic review and meta‐analysis of randomized clinical trials (RCTs) with PARPi either as monotherapy or in combination with an androgen receptor‐targeted agent (ARTA) in first‐ and second‐line settings. …”
Get full text

Low-Dose Caffeine Supplementation Is a Valuable Strategy for Increasing Time to Exhaustion, Explosive Power, and Reducing Muscle Soreness in Professional Male Kickboxers by Maziar Saremi, Fatemeh Shahriari, Mohammad Hemmatinafar, Rasoul Rezaei, Alireza Niknam, Michael Nordvall, Alexei Wong, Reza Bagheri

“…A 1-wk washout period occurred between exercise trials. Caffeine was supplemented 60 min before each exercise session. …”
Get full text

DADmax/NADmax Ratio: Criterion for the Production and Selection of Demolition Aggregates with Low-Water Absorption by Kamel Akroum, Bouzidi Mezghiche

“…Similarly, DA fractions reconstituted from DA sub-fractions of the same PC showed a decrease in minimum values of 21% to 43% compared to average values and 31% to 58% compared to maximum values. …”
Get full text

Efficacy and retention rate of secukinumab in psoriatic arthritis across different clinical phenotypes: insights from the Italian GISEA Registry by Giuseppe Lopalco, Maria Morrone, Fabiola Atzeni, Chiara Bazzani, Francesco Paolo Bianchi, Francesco Paolo Cantatore, Roberto Caporali, Antonio Carletto, Alberto Cauli, Maria Sole Chimenti, Sergio Colella, Fabrizio Conti, Addolorata Corrado, Ennio Giulio Favalli, Alberto Floris, Marco Fornaro, Rosario Foti, Roberta Foti, Elena Fracassi, Bruno Frediani, Stefano Gentileschi, Roberto Gorla, Elisa Gremese, Emanuela Praino, Roberta Ramonda, Cinzia Rotondo, Marco Sebastiani, Angelo Semeraro, Gianfranco Ferraccioli, Giovanni Lapadula, Florenzo Iannone

“…Background: Randomized clinical trials have demonstrated the efficacy of secukinumab (SECU) in reducing disease activity in psoriatic arthritis (PsA), while real-world studies prove a broader perspective on SECU’s usefulness in everyday clinical practice. …”
Get full text

Effects of Nutritional Strategies on Glucose Homeostasis in Gestational Diabetes Mellitus: A Systematic Review and Network Meta-Analysis by Shixiao Jin, Liyan Sha, Jianli Dong, Jing Yi, Yang Liu, Zhongxian Guo, Bing Hu

“…We conducted a literature search using PubMed, EMBASE, and the Cochrane Library to identify randomized controlled trials (RCTs) comparing the differences between different nutritional strategies in women with GDM. …”
Get full text

Supervised vs. Self-Managed Exercise Therapy for Improving Shoulder Function After Traumatic Dislocation and Sprain: A Systematic Review and Meta-Analysis by Daniel Koska, Robert Zetzsche, Tobias A. Mayer, Christian Maiwald

“…Further high-quality trials with standardized protocols and improved adherence tracking are needed to establish more definitive conclusions and guide clinical decision-making.…”
Get full text

Safety and efficacy of anti-CD30 CAR-T cell therapy in relapsed/refractory classic Hodgkin lymphoma: a systematic review and meta-analysis by Fanqiao Meng, Maoyuan Xiang, Yu Liu, Dongfeng Zeng

“…Methods A systematic literature search of PubMed, Cochrane, Embase, ClinicalTrials.gov, and Web of Science databases was conducted until February 2024. …”
Get full text

Ivermectin as a promising therapeutic option for onchocerciasis‐associated epilepsy by Mohammad Amin Manavi, Razieh Mohammad Jafari, Hamed Shafaroodi, Mohammad Sharifzadeh, Ahmad Reza Dehpour

“…However, there is a need for more randomized controlled trials specifically evaluating ivermectin's impact on seizures in O. volvulus‐infected epileptics on ASMs. …”
Get full text

The Effect of Autologous Platelet Rich Plasma on Endometrial Receptivity: A Narrative Review by Milan Stefanović, Predrag Vukomanović, Ranko Kutlesic, Milan Trenkić, Vanja Dimitrov, Aleksa Stefanović, Vladimir Cvetanović

“…Obtained articles were screened, and suited studies (randomized controlled trials, case reports, case series, pilot studies, and reviews) were included in the present review. …”
Get full text

Performance of 1-year-old camel calves fed a basal ration of alfalfa hay supplemented with different levels of concentrate by Ahmed R. Askar, Rawia Darwesh, Sabbah Allam, Galal M. Abdul Aziz, Afaf A. El Shereef, Ehab Y. Eid, Hamedi M. Kandil, Samir S. Abou El Ezz, Mohsen M. Shoukry

“…The experiment lasted for 6 months, in which digestibility trials took place at 14, 16, and 18 months of age, which corresponded to 2, 4, and 6 months of the experimental period. …”
Get full text

Aldosterone Blockade in Acute Myocardial Infarction: A Systematic Review and Meta-Analysis by Qiao Chen, Die Zhao, Jie Sun, Chengzhi Lu

“…Articles were identified through PubMed, Embase, Cochrane Library, Ovid (Medline1946-2021), and ClinicalTrials.gov databases from their inception to December 31, 2020. …”
Get full text

Effectiveness and safety of PD-1/L1 inhibitors as first-line therapy for patients with advanced or metastatic urothelial carcinoma who are ineligible for platinum-based chemotherap... by Weiming Liang, Weiming Liang, Zhijing Wang, Zhilong Huang, Yanping Huang, Chunyan Li, Yiwen Liang, Miaoyan Huang, Duo Zhang, Chenchen Li

“…Specifically, the combination of Enfortumab vedotin (EV) and pembrolizumab (Pembro) showed more effectiveness in treating patients compared to trials using the current standard treatment, suggesting that it could be a promising alternative treatment option.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024510152.…”
Get full text

Effects of exercise interventions on fatigue of hematopoietic stem cell transplantation patients: A Meta-analysis (运动干预对造血干细胞移植患者疲乏影响的Meta分析)... by ZHOU Min (周敏), ZHANG Qing (张清), HU Shaoyan (胡绍燕), ZHOU Xuemei (周雪梅)

“…Methods Randomized controlled trials on exercise intervention in patients with HSCT were retrieved from Cochrane library, PubMed, Web of Science, Embase, CINAHL, CNKI, Wanfang Data, VIP, and CBM databases from the establishment to February 2024; ReMan 5. 3 software was used for meta-analysis. …”
Get full text

Direct anterior approach (DAA) vs. conventional approaches in total hip arthroplasty: A RCT meta-analysis with an overview of related meta-analyses. by Philip Lazaru, Simon Bueschges, Nikolai Ramadanov

“…<h4>Objectives</h4>Several systematic reviews and meta-analyses on short-term outcomes between total hip arthroplasty (THA) through direct anterior approach (DAA) compared to THA through conventional (including anterior, anterolateral, lateral transgluteal, lateral transtrochanteric, posterior, and posterolateral) approaches (CAs) in treatment of hip diseases and fractures showed contradicting conclusions. Our aim was to draw definitive conclusions by conducting both a fixed and random model meta-analysis of quality randomized controlled trials (RCTs) and by comparison with related meta-analyses.…”
Get full text

Efficacy and safety of gut microbiome-targeted treatment in patients with depression: a systematic review and meta-analysis by Bo Pan, Yiming Pan, Yu-Song Huang, Meng Yi, Yuwei Hu, Xiaoyu Lian, Hui-Zhong Shi, Mingwei Wang, Guifen Xiang, Wen-Yi Yang, Zhong Liu, Fangfang Xia

“…The overall pooled estimates showed that MTT significantly improved depression symptoms (SMD −0.26, 95% CI [−0.32, −0.19], I 2  = 54%) with acceptable safety. …”
Get full text

Clinicopathological and Prognostic Significance of CD47 Expression in Lung Neuroendocrine Tumors by Mario Orozco-Morales, Alejandro Avilés-Salas, Norma Hernández-Pedro, Rodrigo Catalán, Graciela Cruz-Rico, Ana Laura Colín-González, Elsa Dosal-Mancilla, Pedro Barrios-Bernal, Oscar Arrieta

“…The mean age at diagnosis was 57.6 (±11.6) years; 30 patients were women (59%). 27.5% of patients were positive for CD47 expression, and 72.5% of patients showed a CD47 expression of less than 1% and were considered as negatives. …”
Get full text

Molecular-genetic pathways of hepatitis C virus regulation of the expression of cellular factors PREB and PLA2G4C, which play an important role in virus replication by E. L. Mishchenko, A. A. Makarova, E. A. Antropova, A. S. Venzel, T. V. Ivanisenko, P. S. Demenkov, V. A. Ivanisenko

“…Among the viral proteins, NS3 showed the  greatest number of regulatory linkages. …”
Get full text