Electronic patient-reported outcome measures using mobile health technology in rheumatology: A scoping review. by Jaclyn Shelton, Sierra Casey, Nathan Puhl, Jeanette Buckingham, Elaine Yacyshyn

“…<h4>Conclusion</h4>The use of ePROMs in rheumatology is a growing area of research and shows significant utility in clinical practice, particularly in inflammatory arthritis. …”
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Pharmacological and structural insights into nanvuranlat, a selective LAT1 (SLC7A5) inhibitor, and its N-acetyl metabolite with implications for cancer therapy by Chunhuan Jin, Xinyu Zhou, Minhui Xu, Hiroki Okanishi, Ryuichi Ohgaki, Yoshikatsu Kanai

“…Nanvuranlat (JPH203/KYT-0353), a LAT1 inhibitor, has shown antitumor activity in preclinical studies and efficacy in biliary tract cancer during clinical trials. This study provides a comprehensive pharmacological characterization of nanvuranlat and its N-acetyl metabolite, including structural insights into their LAT1 interactions. …”
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Systematic review of interventions for improving the performance of community health workers in low-income and middle-income countries by Paul Montgomery, Madeleine Ballard

“…Randomised controlled trials evaluating interventions to improve CHW performance in low- and middle-income countries were included and appraised for risk of bias. …”
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Comparative efficacy of sleep positional therapy, oral appliance therapy, and CPAP in obstructive sleep apnea: a meta-analysis of mean changes in key outcomes by Yunjun Gao, Sixiang Zhu, Wenjun Li, Youqing Lai

“…This study aimed to compare the efficacy and safety of SPT with CPAP, oral appliance therapy (OAT), and placebo.MethodsNineteen randomized controlled trials (RCTs) with 1,231 participants were included. …”
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Associations between sleep traits and colorectal cancer: a mendelian randomization analysis by Xiangyue Meng, Enshuo Fan, Dan Lv, Yongjing Yang, Shixin Liu

“…Additionally, we conducted sensitivity analyses to minimize possible biases and verify the consistency of our results.ResultsMendelian randomization analyses showed that an morning chronotype reduces the risk of CRC with the IVW method, hence, odds ratio (OR) of 1.21 and 95% confidence interval (CI) of 0.67-0.93, which is statistically significant at P = 5.74E-03. …”
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Effect of Adding Silica Nanoparticles on the Physicochemical Properties, Antimicrobial Action, and the Hardness of Dental Stone Type 4 by Navid Aghbolaghi, Solmaz Maleki Dizaj, Ramin Negahdari, Amir Reza Jamei Khosroshahi, Yashar Rezaei, Sepideh Bohlouli, Mohammad Ali Ghavimi

“…Then, at least 2% silica nanoparticles are needed for a significant increase. Clinical trials are needed to enlarge for dental stone type 4 containing silica nanoparticles in the future.…”
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Effects of proton pump inhibitors and histamine-2 receptor antagonists on response to fidaxomicin or vancomycin in patients with Clostridium difficile-associated diarrhoea by Thomas Louie, Karl Weiss, Mark A Miller, Kathleen Mullane, Derrick W Crook, Sherwood L Gorbach

“…However, it is not known whether the use of PPIs or histamine-2 receptor antagonists (H2RAs) concurrently with CDAD-targeted antibiotic treatment affects clinical response or recurrence rates.Design In two phase 3 trials, patients with toxin-positive CDAD were randomised to receive fidaxomicin 200 mg twice daily or vancomycin 125 mg four times daily for 10 days. …”
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Comparison of GLP-1RAs vs Other Pharmacotherapy for Obesity by Andrew Overholser, Eric Czech, Linda Speer, Joel Wilson, Alex Overholser

“…Results: The literature showed that over 52 weeks, liraglutide reduced mean body weight percentage by 4.81% (95% CI: 4.23%-5.39%). …”
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Universal capillary screening for chronic autoimmune, metabolic and cardiovascular diseases: feasibility and acceptability of the UNISCREEN study by Sara Angiulli, Aurora Merolla, Elisa Borgonovo, Rebecca De Lorenzo, Serena Spadoni, Barbara Fontana, Giuseppina Manganaro, Elena Rela, Alberto Bongiovanni, Rita Peracino, Chiara Bellino, Giulia Pata, Eleonora Bianconi, Sabina Martinenghi, Francesca Ulivi, Cristina Renzi, Cristina Renzi, Emanuele Bosi, Emanuele Bosi, UNISCREEN Study Group, Sara Angiulli, Aurora Merolla, Alberto Bongiovanni, Rebecca De Lorenzo, Elena Rela, Rita Peracino, Chiara Bellino, Giuseppina Manganaro, Elisa Borgonovo, Sara Critelli, Aldo Fici, Martina Mallus, Giulia Morocutti, Giulia Pata, Clara Soggetti, Chiara Calabrese, Alberico Di Resta, Maria Pia Ruggiero, Antonella Spano’, Francesca Biasco, Manuel Stocchi, Pietro Melodia, Giuseppe Ancona, Andrea Laurenzi

“…The study was registered as ClinicalTrials.gov NCT05841719.ResultsThe study included 1,535 participants (50.1% of local population). …”
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Strategies for Selecting Potentially Effective Biofumigant Species for Optimal Biofumigation Outcomes by Juan Manuel Arroyo, Jose Soler, Rubén Linares, Daniel Palmero

“…., cultivated in central Spain. Field trials across two growing cycles assessed biomass production, glucosinolate (GSL) concentration, photosynthetically active radiation (PAR) interception, and radiation use efficiency (RUE). …”
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Nutritional Counseling During Chemotherapy Treatment: A Systematic Review of Feasibility, Safety, and Efficacy by Shalet James, Alexie Oppermann, Kaitlin M. Schotz, Mackenzie M. Minotti, Gautam G. Rao, Ian R. Kleckner, Brenton J. Baguley, Amber S. Kleckner

“…Among 44 publications, 39 studies recruited 98 ± 80 participants (range 15–360); 38/39 (97%) were randomized controlled trials. One-third (31%) were among patients with breast cancer. …”
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Testing Multi-Theory Model (MTM) in Predicting Physical Activity Behavior Among Upper Elementary School Children in Northern India by Poonam KHANNA, Tejinder Pal SINGH, Tarundeep SINGH, Rekha KAUSHIK, Manoj SHARMA

“…More empirical work needs to be undertaken in India, using randomized controlled trials that operationalize expanded form of this model.…”
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Mesenchymal Stem Cells Enhance Pulmonary Antimicrobial Immunity and Prevent Following Bacterial Infection by Wenchao Li, Weiwei Chen, Saisai Huang, Xiaojun Tang, Genhong Yao, Lingyun Sun

“…As a promising substitution/adjunct, mesenchymal stem cells (MSCs) are currently being tested in several clinical trials. However, their influence on the recipients’ antimicrobial immunity remains unclear. …”
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Association of Inflammatory Profile During Ex Vivo Lung Perfusion With High-Grade Primary Graft Dysfunction: A Systematic Review and Meta-Analysis by Andrea Costamagna, Eleonora Balzani, Matteo Marro, Erika Simonato, Alessandro Burello, Mauro Rinaldi, Luca Brazzi, Massimo Boffini, Vito Fanelli

“…This systematic-review and meta-analysis of non-randomized controlled trials on patients undergoing Ltx with reconditioned lungs via EVLP, aims to assess the association between the levels of proinflammatory biomarkers during EVLP and PGD3 development within the firsts 72 h post-Ltx. …”
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Neurovascular bundle sparing in hypofractionated radiotherapy maintained with realistic treatment uncertainties by Roel C. Kwakernaak, Victor J. Brand, Jesús Rojo-Santiago, Femke E. Froklage, Mischa S. Hoogeman, Steven J.M. Habraken, Maaike T.W. Milder

“…The clinical impact of the achieved sparing is subject of ongoing clinical trials.…”
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Extracellular Vesicles Derived from Human Umbilical Mesenchymal Stem Cells Transfected with miR-7704 Improved Damaged Cartilage and Reduced Matrix Metallopeptidase 13 by Kun-Chi Wu, Hui-I Yang, Yu-Hsun Chang, Raymond Yuh-Shyan Chiang, Dah-Ching Ding

“…Therefore, miR-7704-overexpressed EVs derived from HUCMSCs showed potential as an innovative therapeutic strategy for treating OA. …”
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TraxVBF: A hybrid transformer-xLSTM framework for EMG signal processing and assistive technology development in rehabilitation by Seyyed Ali Zendehbad, Athena Sharifi Razavi, Marzieh Allami Sanjani, Zahra Sedaghat, Saleh Lashkari

“…The fact that people with mobility impairments often have great difficulties in performing essential Activities of Daily Living (ADL) shows the importance of developing effective rehabilitation strategies. …”
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Fibrin Glue Enhances Adipose-Derived Stromal Cell Cytokine Secretion and Survival Conferring Accelerated Diabetic Wound Healing by Ursula Hopfner, Matthias M. Aitzetmueller, Philipp Neßbach, Michael S. Hu, Hans-Guenther Machens, Zeshaan N. Maan, Dominik Duscher

“…Although several vehicles have shown to successfully act as cell carrier systems in preclinical trials, regulatory issues have prohibited clinical usage for chronic wounds. …”
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Recent advances in systemic therapy for advanced biliary tract cancer: A systematic review and meta-analysis using reconstructed RCT survival data by Zhihao Li, Daniel Aliseda, Owen Jones, Luckshi Rajendran, Christian Magyar, Robert Grant, Grainne M. O’Kane, Anna Saborowski, Gonzalo Sapisochin, Arndt Vogel

“…Following positive results from the TOPAZ-01 and KEYNOTE-966 trials, immune checkpoint inhibitors (ICIs) combined with chemotherapy are now the standard of care. …”
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Assessment of Bowel Preparation Using Low-Volume Sulphate-Based Preparations in Comparison with Macrogols: A Multicenter, Randomized, Comparative Clinical Study of the 3rd Phase by E. D. Fedorov, V. V. Veselov, S. V. Kashin, E. V. Tikhomirova, A. V. Veselov, D. V. Zavyalov, A. Kornowski, T. E. Gorskaya, M. Volteau, T. Ponchon

“…Despite the higher incidence of nausea in the OSS group, the patients showed significantly higher compliance with the OSS mode as compared to that of Macrogol. …”
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