Carrageenan-Free Diet Shows Improved Glucose Tolerance and Insulin Signaling in Prediabetes: A Randomized, Pilot Clinical Trial by Leo Feferman, Sumit Bhattacharyya, Erin Oates, Nicole Haggerty, Tianxiu Wang, Krista Varady, Joanne K. Tobacman

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A scoping review of randomized trials assessing the impact of n-of-1 trials on clinical outcomes. by Joyce P Samuel, Susan H Wootton, Travis Holder, Donald Molony

“…One trial showed a statistically significant benefit in the primary outcome. …”
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A Simple Spatial Working Memory and Attention Test on Paired Symbols Shows Developmental Deficits in Schizophrenia Patients by Wei Song, Kai Zhang, Jinhua Sun, Lina Ma, Forrest Fabian Jesse, Xiaochun Teng, Ying Zhou, Hechen Bao, Shiqing Chen, Shuai Wang, Beimeng Yang, Xixia Chu, Wenhua Ding, Yasong Du, Zaohuo Cheng, Bin Wu, Shanguang Chen, Guang He, Lin He, Xiaoping Chen, Weidong Li

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Experience in conducting clinical trials in Cienfuegos by Olga Lidia Cuevas Pérez, Diana Rosa Fernández Ruíz, Gredsy Escandón López, Mayra Quirós Enrique, Yuleidis García Rodríguez

“…This is the reason of the importance of showing the growth achived in the province in this activity.…”
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Indirect Comparison Showed Survival Benefit from Adjuvant Chemoradiotherapy in Completely Resected Gastric Cancer with D2 Lymphadenectomy by Qiong Yang, Ying Wei, Yan-Xian Chen, Si-Wei Zhou, Zhi-Min Jiang, De-Rong Xie

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Impaired Hepatitis B and COVID-19 vaccination responses show strong concordance in hemodialysis patients with end stage renal disease by Karsten Lürken, Anna Meinecke, Luis A. Manthey, Anne Cossmann, Metodi V. Stankov, Frank Klawonn, Anna Zychlinsky Scharff, Sandra Steffens, Alexandra Dopfer-Jablonka, Frank Müller, Georg M. N. Behrens, Christine Happle

“…These results may help to adapt vaccination strategies in this highly vulnerable population. Trial registration: German Clinical Trial Registry, DRKS00021152.…”
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The Effectiveness and Safety of Probiotic Supplements for Psoriasis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Preclinical Trials by Liuting Zeng, Ganpeng Yu, Yang Wu, Wensa Hao, Hua Chen

“…The databases were utilized to search the randomized controlled trials (RCTs) and preclinical trials about probiotic supplement in the treatment of psoriasis. …”
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Discrepancies in safety reporting for chronic back pain clinical trials: an observational study from ClinicalTrials.gov and publications by Nick Boyne, Alison Duke, Jack Rea, Adam Khan, Alec Young, Jared Van Vleet, Matt Vassar

“…Serious adverse events (SAEs) were reported differently in 15 (37.5%) publications; 80% reported fewer SAEs than ClinicalTrials.gov. Other adverse events (OAEs) showed discrepancies in 37 (92.5%) publications, with 43.2% reporting fewer and 54.1% reporting more OAEs. …”
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Proceedings of clinical trials on bile tract cancer by XIONG Yichen, YANG Ziyi, SANG Yuer, GONG Wei

“…The results of several large-scale multicenter prospective clinical trials about BTC were published. All of these are significant for optimizing therapeutic strategies for BTC. …”
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The Right to a Fair Trial Under Article 6 ECHR During the Covid-19 Pandemic: by Andrzej Paduch

“…Public hearing is in fact a crucial aspect of the right to a fair trial. However, in order to mitigate the effects of a pandemic, states may introduce such solutions which – within the limits of art. 6 sec. 1 ECHR – modify the law. …”
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Insights from serial cardiovascular magnetic resonance imaging show early progress in diastolic dysfunction relates to impaired right ventricular deformation by Sören J. Backhaus, Alexander Schulz, Torben Lange, Simon F. Rösel, Lennart S. Schmidt-Schweda, Shelby Kutty, Johannes T. Kowallick, Julia Treiber, Andreas Rolf, Samuel Sossalla, Gerd Hasenuß, Andreas Schuster

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Female Sprague Dawley Rats Show Impaired Spatial Memory in the 8-Arm Radial Maze under Dim Blue and Red Light by Michael Pirchl, Georg Kemmler, Christian Humpel

“…The aim of the present study was to explore if dim white (7.6–17.7 lux) , blue (1.3–2.3 lux), and red light (0.8–1.4 lux) affect spatial memory of male and female Sprague Dawley rats in the 8-arm radial maze. Our data show that spatial memory significantly improved within 5 daily learning sessions (each 5 trials) under dim white light, which was not different between male and female rats. …”
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The Effect of Diacerein on Type 2 Diabetic Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis by Shizhe Guo, Xianshan Guo, Hongya Zhang, Xuan’e Zhang, Zhen Li

“…An electronic search was processed on Pubmed, Embase, and Cochrane library for randomized controlled trials (RCTs) comparing the efficacy of diacerein with placebo on T2DM. …”
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Efficacy of 2‐Mercaptoethane Sulfonate Sodium (MESNA) in the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography: A Randomized Open Label Trial by Amir Sadeghi, Hesamoddin Samar, Mohammad Abbasinazari, Parvaneh Mohammadi, Ali Abazarikia, Shadi Ziaie

“…Methods An open‐labeled clinical trial was done on 698 participants undergoing endoscopic retrograde cholangiopancreatography (ERCP). …”
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VOLUNTEER ORGANIZATION AS A SCHOOL OF STUDENTS’ VOCATIONAL TRIALS by V. A. Starodubtsev, Р. V. Rodionov

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Single-Cell Analyses Reveal Necroptosis’s Potential Role in Neuron Degeneration and Show Enhanced Neuron-Immune Cell Interaction in Parkinson’s Disease Progression by Xiaomei Zeng, Zhifen Han, Kehan Chen, Peng Zeng, Yidan Tang, Lijuan Li

“…Our analyses provide insights into the causes of neuron death and inflammation in PD from single-cell resolution, which could be seriously considered in clinical trials.…”
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Self-administered active versus sham acupressure for diarrhea predominant irritable bowel syndrome: a nurse-led randomized clinical trial by Maha Gamal Ramadan Asal, Ahmed Abdelwahab Ibrahim El-Sayed, Samira Ahmed Alsenany, Zahraa Hassan Ramzy, Rasha Fathy Ahmed Dawood

“…Aim This randomized controlled trial aimed to evaluate the effect of active acupressure compared to sham acupressure on primary and secondary outcomes among IBS-D patients. …”
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Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study by Anna Persson, Anna Persson, Daniel Wallhed Finn, Alice Broberg, Amanda Westerberg, Åsa Magnusson, Åsa Magnusson, Olof Molander

“…Negative effects were reported in terms of increased adverse emotional experiences.DiscussionThe investigated integrated treatment for co-occurring depression and alcohol use disorder continues to show promise. Randomized clinical trials are needed to evaluate its effectiveness.…”
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The Bipolar Depression Electrical Treatment Trial (BETTER): Design, Rationale, and Objectives of a Randomized, Sham-Controlled Trial and Data from the Pilot Study Phase by Bernardo de Sampaio Pereira Junior, Gabriel Tortella, Beny Lafer, Paula Nunes, Isabela Martins Benseñor, Paulo Andrade Lotufo, Rodrigo Machado-Vieira, André R. Brunoni

“…We describe a randomized, sham-controlled, double-blinded trial using tDCS for refractory, acutely symptomatic BD (the bipolar depression electrical treatment trial, BETTER). …”
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Tailored exercise and manual therapy versus standardised exercise for patients with shoulder subacromial pain: a feasibility randomised controlled trial (the Otago MASTER trial) by J Haxby Abbott, Daniel C Ribeiro, Zohreh Jafarian Tangrood, Gisela Sole, Ross Wilson

“…Adverse events (n=2, only in the tailored group) were minor in nature and included skin injury or pain following taping.Conclusions Our feasibility trial showed that additional strategies are required for improving recruitment, enrolment and minimising drop-out of participants into the trial and making it feasible to conduct a full trial.Trial registration number ANZCTR: 12617001405303.…”
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